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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/2.12/bioc/html/DNAcopy.html
Software that segments DNA copy number data using circular binary segmentation to detect regions with abnormal copy number.
Proper citation: DNAcopy (RRID:SCR_012560) Copy
http://www.scienceexchange.com/facilities/labospace-uk-ltd
LaboSpace is a laboratory service provider with branches in UK and Italy operating in the area of Immunology, Cancer Research, Neuroscience, Cardiovascular Disease, Endocrinology and Target Therapy application. LaboSpace services for the research market cover IHC validation, Multiplex IHC, Luminex and Elisa assays platform, DNA/RNA large HTS extraction. In May 2011 LaboSpace was granted by the Local Government of the accreditation as Diagnostic laboratory. Currently applying for ISO9001:2008 and ISO13485
Proper citation: LaboSpace (RRID:SCR_012404) Copy
https://us.progen.com/About-Us/
ProGen - Protein & Gene Engineering specializes in custom molecular biology services including DNA cloning, sub-cloning, codon optimized artificial gene synthesis, site-directed mutagenesis and large scale custom projects such as DNA isolation and purification. The custom products of the company are used for gene engineering to study gene expression regulatory mechanisms, protein engineering, and analysis of gene and protein function. Customers of the company include research laboratories in academia, clinical researchers in medical institutes and biotechnology companies. In addition to our custom cloning services, as an authorized Israeli representative of SBS Genetech Co., we market molecular biology products of SBS at competitive prices. SBS is one of the largest sources of synthetic oligonucleotides. The range of the products cover biochemicals, enzymes and PCR products. As a young company we are highly motivated to deliver high quality services and products at lowest prices with a rapid schedule of delivery. We guarantee full customer satisfaction on all products and services.
Proper citation: ProGen - Protein and Gene Engineering (RRID:SCR_012405) Copy
https://www.q2labsolutions.com/genomics-laboratories
Core provides whole genome to focused set gene expression and genotyping assays along with DNA sequencings services, sequence enrichment technologies and bioinformatics support. Platforms utilized include Affymetrix GeneChip, Agilent Sure Select, Fluidigm Access Arrays, Illumina BeadChip, iScan, Genome Analyzer and Hi-Seq, RainDance Technologies RDT 1000 and, the Pacific Biosciences PacBio RS. Expression Analysis offers solutions for challenging specimens such as whole blood and FFPE tissues, as well as nucleic acid isolation and data analysis services.
Proper citation: Q Squared Solutions Expression Analysis (RRID:SCR_012497) Copy
https://www.eaglegenomics.com/
Core provides outsourced bioinformatics solutions. Core combines cloud computing and Next Generation Sequencing (NGS) expertise with a track record in building scalable, efficient genomics analysis workflows using both commercial and open source software. Core has provided services to big pharma, crop science, personal hygiene and animal health.
Proper citation: Eagle Genomics Limited (RRID:SCR_012543) Copy
Catalog of published genome-wide association studies. Genome-wide set of genetic variants in different individuals to see if any variant is associated with trait and disease. Database of genome-wide association study (GWAS) publications including only those attempting to assay single nucleotide polymorphisms (SNPs). Publications are organized from most to least recent date of publication. Studies are identified through weekly PubMed literature searches, daily NIH-distributed compilations of news and media reports, and occasional comparisons with an existing database of GWAS literature (HuGE Navigator). Works with HANCESTRO ancestry representation.
Proper citation: GWAS: Catalog of Published Genome-Wide Association Studies (RRID:SCR_012745) Copy
http://www.scienceexchange.com/facilities/lifetein
LifeTein LLC, located in South Plainfield, New Jersey, was founded for its global custom peptide synthesis services, antibody production services and chemical services. LifeTein offers a wide range of custom research services and a staff of scientists with the first-hand campus-core-facility experience necessary to understanding the role of peptide and protein services in large research projects. LifeTein is the only peptide synthesis manufacturer to have developed its own line of PeptideSyn platform for peptide synthesis and AdjuBooster for antibody production.
Proper citation: LifeTein (RRID:SCR_012626) Copy
http://www.brain.northwestern.edu/index.html
The Cognitive Neurology and Alzheimer's Disease Center (CNADC) is a multidisciplinary organization dedicated to conducting research to discover how the brain coordinates mental functions such as memory, language, attention, and emotion; transferring the benefits of this research to patients with brain diseases that impair cognitive function; and training researchers and clinicians who want to work in this field. The CNADC's mission is to investigate the neurological basis of cognitive function, to elucidate causes of dementia, and to ensure that the patients and their families are the beneficiaries of resultant discoveries. * Clinical Services: Neurobehavior and Memory Health Clinical Services * Annual Grant Opportunities: Annual Core Pilot Project Funding Opportunities * Research Areas & Faculty: Alzheimer's Disease / Primary Progressive Aphasia / Frontal Dementia, Brain Endowment (Brains are permanently stored, and requests for tissue for research purposes are submitted to Dr. Bigio for review by the Northwestern Alzheimer's Disease Center); Cognitive Brain Mapping Group, Volunteer For A Study * Fellowships: Neuropathology Fellowship, Behavioral Neurology & Neuropsychiatry Fellowship * Training Programs: Mechanisms of Aging and Dementia (M.A.D.) Training Program; Training Program in the Neuroscience of Human Cognition
Proper citation: Northwestern University Cognitive Neurology and Alzheimers Disease Center (RRID:SCR_012747) Copy
http://www.scienceexchange.com/facilities/intrepid-bioinformatics
Core offers a repository from which researchers can drag and drop genetic sequence data into another application. Core offers a feature-surface to surface interoperation-that enables the system to be the hub for a network of applications researchers need to perform their work; LIMS, analytic tools, content management, workflow engines, visualization, etc. The core's system is optimized for cloud-based operations, and doesn't require users to re-download data.
Proper citation: Intrepid Bioinformatics (RRID:SCR_012625) Copy
Software suite of automated docking tools. Designed to predict how small molecules, such as substrates or drug candidates, bind to receptor of known 3D structure. AutoDock consist of AutoDock 4 and AutoDock Vina. AutoDock 4 consists of autodock to perform docking of ligand to set of grids describing target protein, and autogrid to pre calculate these grids.
Proper citation: AutoDock (RRID:SCR_012746) Copy
http://www.scienceexchange.com/facilities/altabioscience
Founded in 1973, AltaBioscience* is recognised world-wide as a leading manufacturing laboratory providing analysis and synthesis of DNA, proteins and other biochemical molecules to researchers in academia, pharmaceutica and the food industry. *An ISO 9001: 2008 certified UK based laboratory offering CD analysis.
Proper citation: AltaBioscience (RRID:SCR_012593) Copy
http://www.bioconductor.org/packages/release/bioc/html/ExiMiR.html
R functions for the normalization of Exiqon miRNA array data.
Proper citation: ExiMiR (RRID:SCR_012753) Copy
http://sourceforge.net/projects/cnv/
Software for a web-enabled platform for analyzing genome variation such as copy number variation (CNV).
Proper citation: CNV Workshop (RRID:SCR_012635) Copy
A global evaluation of the conservation status of plant and animal species. The IUCN Red List plays a prominent role in guiding conservation activities of governments, NGOs and scientific institutions. The introduction in 1994 of a scientifically rigorous approach to determine risks of extinction that is applicable to all species, has become a world standard. In order to produce The IUCN Red List of Threatened Species, the IUCN Global Species Programme working with the IUCN Survival Commission (SSC) and with members of IUCN draws on and mobilizes a network of scientists and partner organizations working in almost every country in the world, who collectively hold what is likely the most complete scientific knowledge base on the biology and conservation status of species. The IUCN Red List is underpinned by information management tools (the Species Information Service) which facilitate the collection, management and processing of species data from workshop to publication on The IUCN Red List.
Proper citation: IUCN (RRID:SCR_012758) Copy
http://www.bioconductor.org/packages/release/bioc/html/motifRG.html
Software tools for discriminative motif discovery using regression methods.
Proper citation: motifRG (RRID:SCR_012602) Copy
We provide high quality Drosophila transgenic service to both research institutions and companies. We offer you partial to full service ranging from DNA preparation, embryo microinjection, screening for white+, yellow+, and/or GFP/RFP phenotypes, to balancing crosses. Most importantly, the cost of our Drosophila embryo injection services is more reasonable compared to that of others. With a large number of facilities and the highly experienced staff, we are able to initiate the process immediately upon receiving your sample. Our friendly web-based database allows you to track your sample status, service history and more.
Proper citation: BestGene (RRID:SCR_012605) Copy
An international professional association of 24,000 neurologists and neuroscience professionals dedicated to promoting the highest quality patient-centered neurologic care. They provide guidance and inspiration through education, information, policy development and advocacy for our members and their patients. The Academy''s professional website is only one of the domains associated with the AAN: * TheBrainMatters.org, public & patient education website * m.AAN.com, mobile AAN.com for members * Neurology journal * Neurology Now, patient magazine * Neurology Today, magazine for neurology professionals The AAN is committed to bringing its members the highest quality continuing medical education and professional education opportunities. The Academy''s Education programs cover the spectrum of neurological disorders, from the most prevalent to newly emerging issues. The AAN also provides a wide range of program formats, including in-depth print, convenient online, and hands-on workshop options. The AAN Annual Meeting brings together more than 10,000 neuroscience professionals for one of the world''s largest neurology gatherings. It has long been a leading showcase for the latest developments in scientific research, and the place to honor peers at the forefront of the work. The AAN offers a variety of publications, news, blogs, jobs, and practice guidelines.
Proper citation: American Academy of Neurology (RRID:SCR_012739) Copy
http://www.bioconductor.org/packages/release/bioc/html/MiRaGE.html
Software package that contains functions for inference of target gene regulation by miRNA, based on only target gene expression profile.
Proper citation: MiRaGE (RRID:SCR_012738) Copy
https://www.nia.nih.gov/alzheimers
Portal for Alzheimer's disease that compiles, archives and disseminates information about current treatments, diagnostic tools and ongoing research for health professions, people with AD, their families and the public. The Center provides informational services and referrals for AD symptoms, diagnosis and treatment for patients; clinical trial information and literature searches for researchers; training materials and guidelines for caregivers; and Spanish language resources.
Proper citation: Alzheimer's Disease Education and Referral Center (RRID:SCR_012787) Copy
The Samuel Roberts Noble Foundation is an independent, nonprofit institute headquartered in Ardmore, Okla. Founded in 1945, the Noble Foundation conducts direct operations, including assisting farmers and ranchers, and conducting plant science research and agricultural programs, to enhance agricultural productivity regionally, nationally and internationally. Employing more than 360 persons, the Noble Foundation conducts its operations through the activities of three operating divisions: * Agricultural Division: Serving a 47-county area within a 100-mile radius of the Noble Foundation''s headquarters in Ardmore, Okla., the Agricultural Division assists more than 1,700 regional farmers and ranchers in achieving their individual financial, production, stewardship and quality-of life goals. * Plant Biology Division: The Plant Biology Division conducts basic biochemical, genetic and genomic plant research for the purpose of improving crop productivity and value, and enhancing animal and human health. * Forage Improvement Division: The Forage Improvement Division translates basic plant science research into tangible plant varieties. Within the institution, the Forage Improvement Division serves as a link between the discoveries in the laboratory and the field, where such discoveries are intended to enhance agricultural outcomes in Oklahoma and around the world. The coordinated efforts of these operating divisions enable the Noble Foundation agricultural specialists and scientists to move science and innovation from the laboratory to the field, giving life to discovery and improving agriculture in Oklahoma, in the United States and around the world.
Proper citation: Samuel Roberts Noble Foundation (RRID:SCR_012794) Copy
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