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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Core that provides investigators with access to adipose tissue samples from well-characterized subjects. It also assists investigators with analysis of adipose tissue morphology and metabolism, specialized cell and organ culture methods, and analysis of gene and protein expression.
Proper citation: Mid-Atlantic Nutrition Obesity Research Center Biological Mechanisms and Functional Genomics Core (RRID:SCR_015432) Copy
http://bnorc.org/cores/transgenic.html
Core that utilizes investigator-derived DNA constructs or investigator derived (or obtained) genetically modified embryonic stem cells to create founder transgenic organisms that can be used to address questions relevant to obesity, diabetes and nutrition, including questions related to brain control of feeding, metabolism and reward.
Proper citation: Boston Nutrition and Obesity Research Centers Transgenic Core (RRID:SCR_015433) Copy
http://www.medschool.umaryland.edu/norc/Cores/Biostatistics--Medical-Informatics-BMI-Subcore/
Core that provides biostatistical consultation to other investigators who are doing research in the fields of obesity and nutrition at University of Maryland and the Baltimore VA Medical Center. It aims to develop new methods for data collection data from older subjects.
Proper citation: Mid-Atlantic Nutrition Obesity Research Center Biostatistics and Medical Informatics Subcore (RRID:SCR_015434) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/michael-hooker-microscopy-core
Core that provides advanced digital light microscopy, image processing and analysis resources for users from the UNC Chapel Hill campus. It also offers instrumentation and instruction to enable users to acquire, process and analyze images from a wide variety of sample types.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Michael Hooker Microscopy Core Facility (RRID:SCR_015390) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/ClinicalTranslationalCore
Core whose services include biospecimen collection and storage, development of lung imaging outcomes, imaging training, and biostatical analysis.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Clinical Translational Core (RRID:SCR_015391) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/TissueProcurmentandCellCultureCore
Core that provides standardized cell cultures for cystic fibrosis research, notably normal, cystic fibrosis and disease control cells, tissues and fluids. Its functions include tissue procurement, airway epithelial cell isolation and culture, collecting airway surface liquid from in vivo and in vitro samples, genetic manipulation of cell cultures, creating and characterizing novel cell lines, and translation of technology and reagents to the greater cystic fibrosis research community.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Tissue Procurement and Cell Culture Core (RRID:SCR_015394) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/mucuscore
Core that provides a service to quantify the concentration of given mucus samples for both total mucus concentration and the absolute relative contributions of each secreted mucin. It also provides quantitation of extracellular DNA. The mucus biphysics subcore component, provides core users with information on the biophysical properties of the mucus layer and its interaction with the cell surface.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mucus and Mucin Biochemistry and Biophysics Core (RRID:SCR_015393) Copy
http://depts.washington.edu/cfrtc/clinical/
Core that aims to provide preclinical support for novel therapeutics, work with other biomedical cores to enhance and support bacterial and human specimen repositories, and support developmental research and training.
Proper citation: Cystic Fibrosis Center - University of Washington Clinical Core (RRID:SCR_015402) Copy
https://www.uab.edu/medicine/cysticfibrosis/about/assay-core
Core that provides Ussing chamber capabilities and expertise for testing vectoral anion transport in polarized airway epithelial monolayers, and florescent dye-based methods for evaluating CFTR activity in cells grown on coverslips. The core also performs immunolocalization for proteins relevant to cystic fibrosis pathogenesis.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Assay Core (RRID:SCR_015407) Copy
http://depts.washington.edu/cfrtc/inflammation/
Core whose objective is to obtain information on relevant parameters of the host response that is unique to cystic fibrosis using a variety of techniques, including in vivo and in vitro imaging, immunohistochemistry, imaging and image analysis, cells and bacteria in tissues, and quantification of chemokines, cytokines, and other factors with ELISA.
Proper citation: Cystic Fibrosis Center - University of Washington Host Response Core (RRID:SCR_015405) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/animal-models-core
Core that provides support to investigators who use animal models to study the pathogenesis of cystic fibrosis and who develop gene and other molecular therapies for cystic fibrosis. Specifically, it provides centralized production, care, breeding, genotyping, and quality control of cystic fibrosis mouse and ferret models used by investigators in the Center.
Proper citation: University of Iowa Center for Gene Therapy Animal Model Core (RRID:SCR_015413) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core
Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.
Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy
http://www.med.unc.edu/cgibd/cores/advanced-analytics
Core facility provides solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Advanced Analytics Core (RRID:SCR_015613) Copy
https://www.kaggle.com/rramele/p300samplingdataset
Dataset replicating the experiment done on BNCI-HORIZON 008-2014 dataset. BCI P300 Speller Kaggle Dataset for Healthy subjects
Proper citation: P300-Dataset (RRID:SCR_015977) Copy
http://sph.unc.edu/norc/nutrigenetics/
Core facility whose services include grant writing assistance and consultation, laboratory analyses, brokerage services, and analytical services.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Nutrigenetics Core (RRID:SCR_015464) Copy
http://sph.unc.edu/norc/metabolic/
Core whose goals are to encourage and facilitate the use of biomarkers for nutritional epidemiological and intervention studies. It provides access to techniques and equipment to bench scientists, as well as assays for investigators without lab facilities.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Metabolic Molecular Phenotyping Core (RRID:SCR_015463) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/proteomicsCore.html
Core facility that uses mass spectrometry coupled to one (1D) and two (2D) dimensional separations by column chromatography or gel electrophoresis to identify, quantify or characterize proteins and their post-translational modifications, that are expressed in well characterized protein fractions from the small intestine, colon, kidney, liver and pancreas. Techniques such as difference gel electrophoresis (DIGE), isobaric tag for relative and absolute quantitation (iTRAQ), tandem mass tags (TMT) and stable isotope labeling of amino acids in cell culture (SILAC) as well as non-labeling methods (MudPIT, multi-dimensional protein identification technology) are available for quantifying relative differences in protein expression and post-translational modifications, such as acetylation, glycosylation, phosphorylation, nitrosation, ubiquitination and novel cleavage sites.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Proteomics Core (RRID:SCR_015597) Copy
http://www.norc.uab.edu/corefacilities/physicalactivity
Core that provides physical activity services and consultation for UAB investigators. Services include aerobic fitness tests, supervised resistance training, submaximal ease/economy locomotion tests, and strength and functional tests, with respective measurements taken.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Physical Activity Core (RRID:SCR_015474) Copy
http://www.jhugicc.org/GIConteCenter/pages/cores/imagingCore.html
Core facility that provides state-of-art light microscopy technology to the members of the Hopkins Basic Research Digestive Disease Development Center and to the whole Hopkins scientific community.
Proper citation: Hopkins Conte Digestive Diseases Basic and Translational Research Core Center Image Core (RRID:SCR_015593) Copy
https://hddc.hms.harvard.edu/bio-repository-and-data-registry-human-material
Core facility that supports basic, translational, and clinical research in the digestive diseases by providing access to human materials and resources in statistics and study design. It also aims to to forge connections and support collaboration between HDDC Clinical Associates and Members, support a well-organized infrastructure for acquisition and storage of clinical samples, and provide professional support in biostatistics and study design to HDDC members and Clinical Associates.
Proper citation: Harvard Digestive Diseases Center Bio-Repository and Data Registry for Human Material (RRID:SCR_015590) Copy
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