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http://www.med.umich.edu/mgpc/cores/pil.htm

Core facility whose services include the following programs: Imaging Core Program, Proteomics Core Program, Protein Folding Core Program, and Consultation.

Proper citation: University of Michigan Center for Gastrointestinal Research Protein Localization, Identification and Folding Core (RRID:SCR_015609) Copy   

•   Source: SciCrunch Registry

http://www.mayo.edu/research/centers-programs/obrien-urology-research-center/cores/biostatics-epidemiology

Core that is responsible for all statistical, data management and epidemiological aspects of studies in the Mayo Clinic O'Brien Urology Research Center. Its services include consultation to project investigators regarding study design, data analysis and interpretation of results, maintanence of the Olmsted County kidney stone database, and development of additional linkable databases and quality control procedures.

Proper citation: Mayo Clinic O'Brien Urology Center Biostatistics and Epidemiology Core (RRID:SCR_015452) Copy   

•   Source: SciCrunch Registry

http://www.med.umich.edu/mgpc/cores/maic.htm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 8,2025. Core whose services include consultation, Nucleic Acid Isolation, Microbiome (16S) Data Analysis, MiSeq-base 16S rRNA Gene Sequencing, Genomic/Metagenomic shotgun sequencing, Bacterial transcriptomics and metatranscriptomics, Multiplatform Metabolomic Profiling, Metabolomic sample preparation, and Germ-free & Gnotobiotic Mouse Facilities.

Proper citation: University of Michigan Center for Gastrointestinal Research Microbiome and Metabolomics Core (RRID:SCR_015611) Copy   

•   Source: SciCrunch Registry

http://mmoc.med.umich.edu/CoreMolecularPhenotyping.php

Core that provides analytical tools to MMOC investigators to permit structural identification and quantification of metabolites as well as perform metabolic studies in in vitro systems. It also provides consultation and collaboration to apply metabolomics platforms in nutrition and obesity research.

Proper citation: University of Michigan Nutrition and Obesity Research Center Molecular Phenotyping Core (RRID:SCR_015456) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/clinical-core

Core facility which aims to provide cystic fibrosis researchers with a biobank of archived biosamples collected during routine clinical visits and research-related visits. Biospecimens include normal and CF specimens including DNA, bronchoalveolar lavage fluid, whole blood, plasma, feces, urine, and bacterial isolates. It also aims to facilitate patient recruitment and enrollment in clinical trials.

Proper citation: University of Iowa Center for Gene Therapy Clinical Core (RRID:SCR_015415) Copy   

•   Source: SciCrunch Registry

http://www.norch.org/center-cores/genomics-and-cell-biology-core/

Core that facilitates the application of genomics, bioinformatics, cell biology, and immunology techniques to nutrition and metabolic research.

Proper citation: Nutrition and Obesity Research Centers at Harvard Genomics and Cell Biology Core (RRID:SCR_015427) Copy   

•   Source: SciCrunch Registry

http://www.medschool.umaryland.edu/norc/Cores/Clinical--Translational-Research-CTR-Core/

Core that facilitates the conduct of clinical nutrition and obesity research. Its team of experts in nutrition, exercise physiology, body composition, metabolism and behavioral therapy aim to assist and train NORCH investigators in the skills necessary to conduct clinical nutrition and obesity research.

Proper citation: Mid-Atlantic Nutrition Obesity Research Center Clinical and Translational Research Core (RRID:SCR_015431) Copy   

•   Source: SciCrunch Registry

http://www.medschool.umaryland.edu/norc/Cores/Biological-Mechanisms-and-Functional-Genomics-BMFG-Core/

Core that provides investigators with access to adipose tissue samples from well-characterized subjects. It also assists investigators with analysis of adipose tissue morphology and metabolism, specialized cell and organ culture methods, and analysis of gene and protein expression.

Proper citation: Mid-Atlantic Nutrition Obesity Research Center Biological Mechanisms and Functional Genomics Core (RRID:SCR_015432) Copy   

•   Source: SciCrunch Registry

http://bnorc.org/cores/transgenic.html

Core that utilizes investigator-derived DNA constructs or investigator derived (or obtained) genetically modified embryonic stem cells to create founder transgenic organisms that can be used to address questions relevant to obesity, diabetes and nutrition, including questions related to brain control of feeding, metabolism and reward.

Proper citation: Boston Nutrition and Obesity Research Centers Transgenic Core (RRID:SCR_015433) Copy   

•   Source: SciCrunch Registry

http://www.medschool.umaryland.edu/norc/Cores/Biostatistics--Medical-Informatics-BMI-Subcore/

Core that provides biostatistical consultation to other investigators who are doing research in the fields of obesity and nutrition at University of Maryland and the Baltimore VA Medical Center. It aims to develop new methods for data collection data from older subjects.

Proper citation: Mid-Atlantic Nutrition Obesity Research Center Biostatistics and Medical Informatics Subcore (RRID:SCR_015434) Copy   

•   Source: SciCrunch Registry

https://www.niddkrepository.org/studies/cpcrn2-rct1/

Clinical trial by the Chronic Prostatitis Collaborative Research Network (CPCRN chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)) that was established to conduct randomized clinical trials of promising therapies for this syndrome. In response to the findings of previous trials, the CPCRN conducted a multicenter, randomized, placebo-controlled trial of alfuzosin to determine whether the symptoms CP/CPPS could be reduced in men who had recently received a diagnosis of CP/CPPS and who had not previously been treated with this class of drug.

Proper citation: Chronic Prostatitis Collaborative Research Network Clinical Trial- Alfuzosin (RRID:SCR_015886) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/assay-core

Core that provides Ussing chamber capabilities and expertise for testing vectoral anion transport in polarized airway epithelial monolayers, and florescent dye-based methods for evaluating CFTR activity in cells grown on coverslips. The core also performs immunolocalization for proteins relevant to cystic fibrosis pathogenesis.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Assay Core (RRID:SCR_015407) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/cfrtc/inflammation/

Core whose objective is to obtain information on relevant parameters of the host response that is unique to cystic fibrosis using a variety of techniques, including in vivo and in vitro imaging, immunohistochemistry, imaging and image analysis, cells and bacteria in tissues, and quantification of chemokines, cytokines, and other factors with ELISA.

Proper citation: Cystic Fibrosis Center - University of Washington Host Response Core (RRID:SCR_015405) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/animal-models-core

Core that provides support to investigators who use animal models to study the pathogenesis of cystic fibrosis and who develop gene and other molecular therapies for cystic fibrosis. Specifically, it provides centralized production, care, breeding, genotyping, and quality control of cystic fibrosis mouse and ferret models used by investigators in the Center.

Proper citation: University of Iowa Center for Gene Therapy Animal Model Core (RRID:SCR_015413) Copy   

•   Source: SciCrunch Registry

https://medicine.uiowa.edu/genetherapy/research-cores/comparative-pathology-core

Core facility which provides comprehensive necropsy, histology, and pathology services for animal models in order to facilitate translational research in animal models of cystic fibrosis. It also houses instrumentation which allows for high-throughput optimization of immunostaining protocols and has access to morphologic equipment that allow for the scanning of large tissue areas and morphometric quantification of histologic endpoints.

Proper citation: University of Iowa Center for Gene Therapy Comparative Pathology Core (RRID:SCR_015411) Copy   

•   Source: SciCrunch Registry

https://www.kaggle.com/rramele/p300samplingdataset

Dataset replicating the experiment done on BNCI-HORIZON 008-2014 dataset. BCI P300 Speller Kaggle Dataset for Healthy subjects

Proper citation: P300-Dataset (RRID:SCR_015977) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/ips-core

The new iPSC Core generates custom-designed iPSCs from mouse and human cells, including disease-specific human iPSCs. iPSCs from other species are currently under development. The Core is currently using both lentiviral- and sendai viral vector systems to deliver reprogramming factors to cells. Both systems are efficient, with the latter system having the advantage to generate iPSCs with a non-DNA-integrating vector system.

Proper citation: CU Denver iPSC Core (RRID:SCR_012176) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/microbiome

Core facility that provides the research community with the facilities and the expertise to characterize complex microbial communities from different environments.Services offered by the Core include metagenomics methods to determine the composition and function of microbial communities using amplicon, Whole Genome Shotgun (WGS) and RNA sequencing, and traditional and high-throughput quantitative (q)PCR.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Microbiome Core (RRID:SCR_012644) Copy   

•   Source: SciCrunch Registry

http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06718

Data set on the prevalence of self-care behaviors by non-institutionalized older adults. Personal interviews were conducted with 3,485 individuals 65 years of age and older, with oversampling of the oldest old. Questions were asked about the type and extent of self-care behaviors for activities of daily living, management of chronic conditions (through self-care activities, equipment use, and environmental modifications), medical self-care for acute conditions, health promotion/disease preventions, social support, health service utilization, and socio-demographic/economic status. A follow-up study by telephone was conducted in 1994 to continue examination of subjects. Many of the same questions from the baseline were asked, along with questions regarding change in health status since baseline and nursing home visits. For subjects who had been institutionalized since baseline (Part 2), information was gathered (by proxy) regarding demographic status, living arrangements prior to institutionalization, and reasons for institutionalization. For subjects who had died since baseline (Part 3), information was again gathered through interviews with proxies. Questions covered nursing home admissions and date and place of death. In both waves, a proxy was substituted if the subject was hospitalized (or institutionalized since baseline), too ill, cognitively not able to respond, or deceased. Survey data were linked to Medicare/Medicaid health utilization records. The baseline data are archived at NACDA as ICPSR Study No. 6718, and the followup data are archived as ICPSR Study No. 2592 and linkable to the baseline data. * Dates of Study: 1990-1994 * Study Features: Longitudinal * Sample Size: ** 1990-1: 3,485 (Baseline) ** 1994: 2,601 (Followup) Links: * 1990-1991 Baseline ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/06718 * 1994 Follow-up ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/02592

Proper citation: National Survey of Self-Care and Aging (RRID:SCR_013456) Copy   

•   Source: SciCrunch Registry

http://clinicaltrials.gov/show/NCT00143949

Randomized, multicenter, double-blind study to determine if renin angiotensin medications, either losartan (angiotensin II blocker) or enalapril (converting enzyme inhibitor), can prevent or delay the onset of diabetic kidney disease in patients with type 1 diabetic patients who do not have hypertension, diabetic nephropathy, or predictive levels of microalbuminuria. Two hundred eight five patients ages 16-61 with 2-20 yrs of Type 1 Diabetes Mellitus and no renal functional abnormalities were randomized into a parallel, double-blind, placebo-controlled study involving 3 groups (95 patients/group). Each group received an angiotensin-converting enzyme inhibitor (ACEI) (enalapril), or an angiotensin II receptor blocker (Losartan), or placebo. All patients had their usual Diabetes Mellitus (DM) management. Baseline studies included measures of glomerular filtration rate (GFR), urinary albumin excretion rate (UAE), blood pressure (BP), and a percutaneous renal biopsy. Patients were followed by quarterly measures of BP, HbA1C, UAE, and drug compliance. There were annual measures of GFR and a repeat renal biopsy after 5 yrs in the study. The main endpoint is kidney structural changes over time, especially mesangial fractional volume (v(Mes/glom)). Secondary endpoints will be other DN structural measures and measures of kidney function (UAE, GFR). These studies will determine whether rennin angiotensin system blockage in the early stages of DN can prevent the early kidney structural changes in this important disorder. Ancillary studies will evaluate the effects of treatment group on the development and progression of diabetic retinopathy and will develop predictors of study participants'''' compliance. Baseline, 2.5 and 5 year retinal fundus photographs in the RASS patients were obtained.

Proper citation: Renin Angiotensin System Study (RRID:SCR_013385) Copy   

•   Source: SciCrunch Registry