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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.nitrc.org/projects/dalan/
Atlas of human white matter diffusion streamlines for predicting medium/long range brain connectivity. The atlas uses the popular Harvard-Oxford (H-O) cortical and subcortical atlas as endpoint targets so that WM connectivity deficits can be analyzed in conjunction with corresponding GM deficits.
Proper citation: DALAN Atlas (RRID:SCR_016262) Copy
http://galaxy.cineca.it/fusion/main
Portal provides an easy access to a comprehensive database designed for storing, displaying and annotating gene fusion events detected from NGS data. It can query a database of somatic fusion genes events predicted and annotated starting from paired-end RNA-seq data.
Proper citation: LiGeA (RRID:SCR_015940) Copy
https://CRAN.R-project.org/package=TrumpetPlots
Software R package to visualize relationship between allele frequency and effect size in genetic association studies.
Proper citation: TrumpetPlots (RRID:SCR_023742) Copy
Commercial medical device company focused on developing minimally disruptive surgical products and procedures for spine.
Proper citation: NuVasive Inc. (RRID:SCR_010564) Copy
http://www.donorsiblingregistry.com/
Registry to assist individuals conceived as a result of sperm, egg or embryo donation that are seeking to make mutually desired contact with others with whom they share genetic ties. They are all about educating, connecting, and supporting donor families. Without any outside support, the DSR has single-handedly pioneered a national discussion about the donor conception industry and families, with it''s many media appearances and interviews. DSR advocates for the right to honesty and transparency for donor kids, and for social acceptance, legal rights and valuing the diversity of all families. The DSR''s core value is honesty, with the conviction that people have the fundamental right to information about their biological origins and identities. The donor conception industry is largely a for-profit enterprise, and after the product has been purchased, most doctors, clinics, egg donation agencies and cryobanks do not engage in discussions and activities which acknowledge the humanity and rights of the donor-conceived. It is our mission to bring these concepts to the public arena for discussion, as has been done in many European countries, as well as New Zealand and parts of Australia. Although you do not need to make a posting to browse the database, it is strongly recommended. Creating a posting in our database is the first step to ensuring the best possible chances of connecting with your biological relatives. If two users with the same donor number browse, but neither post, the connection cannot be made. Many folks are out there waiting to see someone else post for their donor number first! The DSR hope that this will be the first step in connecting with your donor relatives, but please always exercise sensible caution when making contact with those you meet through any internet website, including the DSR.
Proper citation: Donor Sibling Registry (RRID:SCR_010720) Copy
http://alzheimer.ucdavis.edu/research/resources.php#tissue
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. Support research in Alzheimer's disease (AD) offering pilot grants, recruitment of research subjects, access to database, tissue samples, and statistical and research study design consultation for investigators. The scientific effort of the program seeks to: promote research directed at understanding factors that influence the expression and progression of Alzheimer's disease; develop and maintain cohorts of carefully diagnosed and well characterized research subjects available for research studies on Alzheimer's disease and dementia; provide support to investigators in subject recruitment, clinical research, experimental design, and statistical analysis of data; and maintain a variety of samples (brain, DNA, serum) and an extensive electronic database suitable for developing new research and supporting existing programs.
Proper citation: UC Davis Alzheimers Disease Center - Resources (RRID:SCR_010699) Copy
http://www.evocontology.org/site/Main/EvocOntologyDotOrg
THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone., documented September 6, 2016. Set of orthogonal controlled vocabularies that unifies gene expression data by facilitating a link between the genome sequence and expression phenotype information. The system associates labelled target cDNAs for microarray experiments, or cDNA libraries and their associated transcripts with controlled terms in a set of hierarchical vocabularies. eVOC consists of four orthogonal controlled vocabularies suitable for describing the domains of human gene expression data including Anatomical System, Cell Type, Pathology and Developmental Stage. The four core eVOC ontologies provide an appropriate set of detailed human terms that describe the sample source of human experimental material such as cDNA and SAGE libraries. These expression terms are linked to libraries and transcripts allowing the assessment of tissue expression profiles, differential gene expression levels and the physical distribution of expression across the genome. Analysis is currently possible using EST and SAGE data, with microarray data being incorporated. The eVOC data is increasingly being accepted as a standard for describing gene expression and eVOC ontologies are integrated with the Ensembl EnsMart database, the Alternate Transcript Diversity Project and the UniProt Knowledgebase. Several groups are currently working to provide shared development of this resource such that it is of maximum use in unifying transcript expression information.
Proper citation: eVOC (RRID:SCR_010704) Copy
http://www.fisherbioservices.com/
Biological material management services provider including biospecimen storage, biobanking services, specimen collection kits, sample processing, DNA /RNA extraction and amplification, sample storage, distribution, and clinical trial support. They also offer transport and storage of active pharmaceutical ingredient(s) (API and bio-API), including cryogenic. They can assist with public health research, phase I???????????????IV studies, prospective and retrospective studies, IND/NDA submissions to the FDA, and entry of biotherapeutics into the commercial marketplace.
Proper citation: Fisher BioServices (RRID:SCR_010528) Copy
A company which specializes in producing calcium-based products, particularly hydroxyapatite and tricalcium phosphate. Their activities are focussed on synthetic bone graft substitutes, sustained-release drug delivery devices, and applications of HAP for protein purification.
Proper citation: Berkeley Advanced Biomaterials Inc. (RRID:SCR_010539) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 2nd, 2022. Tissue bank and service organization for bioimplants.
Proper citation: Surgical Biologics - a MiMedx Group Company (RRID:SCR_010661) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 2nd, 2022. Manufacturer of Dermagraft, a bio-engineered skin substitute that assists in restoring damaged tissue and supports the body's natural healing process.
Proper citation: Advanced Biohealing, Inc. (RRID:SCR_010630) Copy
An online database for miRNA target prediction and functional annotations.
Proper citation: miRDB (RRID:SCR_010848) Copy
Web tool to predict biological targets of miRNAs by searching for presence of conserved 8mer, 7mer and 6mer sites that match seed region of each miRNA. Nonconserved sites are also predicted and sites with mismatches in seed region that are compensated by conserved 3' pairing. Used to search for predicted microRNA targets in mammals.
Proper citation: TargetScan (RRID:SCR_010845) Copy
https://esp.gs.washington.edu/
Project focused on understanding the contribution of rare genetic variation to heart, lung and blood disorders through the sequencing of well-phenotyped populations.
Proper citation: NHLBI Grand Opportunity Exome Sequencing Project (RRID:SCR_010798) Copy
http://archive.igbmc.fr/recherche/Prog_FGC/Eq_HGron/Polyphemus.html
R package for comparative analysis of RNA Polymerase II ChIP-Seq profiles by non-linear normalization.
Proper citation: POLYPHEMUS (RRID:SCR_010870) Copy
http://adacgh.bioinfo.cnio.es/
A web tool for the analysis of aCGH data sets. They focus on calling gains and losses and estimating the number of copy changes. Note: ADaCGH will continue being maintained, but is deprecated. Their new tool for CGH and CNV is WaviCGH, http://wavi.bioinfo.cnio.es/
Proper citation: ADaCGH (RRID:SCR_010916) Copy
http://www.zi-mannheim.de/en.html
An independent public foundation of the State of Baden-Wuerttemberg associated with the University of Heidelberg, that is one of Europe''s premier research institutions dedicated to mental health. The CIMH combines a clinical inpatient (300 beds) and outpatient program in adult psychiatry, addiction, childhood and adolescent psychiatry and psychotherapy with outstanding research facilities, including two dedicated research fMRI scanners (currently 1.5 Ts and 3 Ts, from next summer 2 3 Ts magnets), an 9.4 Ts animal fMRI scanner, high-throughput facilities for genotyping and molecular biology, neuropsychology and an extensive transgenic animal (both mice and rats) and animal behavior assessment facility.
Proper citation: Central Institute of Mental Health; Mannheim; Germany (RRID:SCR_011144) Copy
https://www.ncbi.nlm.nih.gov/pubmed/18174824
A face-to-face household survey of assessing the prevalence of mental health disorders in a probability sample of 3005 adolescents aged 12-17 years residing in the Mexico City metropolitan area during 2005. The prevalence of mental health disorders and the use of services were assessed with the computer-assisted adolescent version of the World Mental Health Composite International Diagnostic Interview.
Proper citation: Mexican Adolescent Mental Health Survey (RRID:SCR_009654) Copy
http://purl.bioontology.org/ontology/EHDAA
A structured controlled vocabulary of stage-specific anatomical structures of the human. It has been designed to mesh with the mouse anatomy and incorporates each Carnegie stage of development (CS1-20). The abstract version of the human developmental anatomy ontology compresses all the tissues present over Carnegie stages 1-20 into a single hierarchy. The heart, for example, is present from Carnegie Stage 9 onwards and is thus represented by 12 EHDA IDs (one for each stage). In the abstract mouse, it has a single ID so that the abstract term given as just ''heart'' really means ''heart (CS 9-20)''. Timing details will be added to the abstract version of the ontology in a future release.
Proper citation: Human Developmental Anatomy Ontology abstract version 1 (RRID:SCR_010323) Copy
http://link.springer.com/article/10.1007%2Fs11357-003-0002-y
A database that stores information on the biomolecules which are modulated during aging and by caloric restriction (CR). To enhance its usefulness, data collected from studies of CR''''s anti-oxidative action on gene expression, oxidative stress, and many chronic age-related diseases are included. AgingDB is organized into two sections A) apoptosis and the various mitochondrial biomolecules that play a role in aging; B) nuclear transcription factors known to be_sensitive to oxidative environment. AgingDB features an imagemap of biomolecular signal pathways and visualized information that includes protein-protein interactions of biomolecules. Authorized users can submit a new biomolecule or edit an existing biomolecule to reflect latest developments.
Proper citation: AgingDB (RRID:SCR_010226) Copy
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