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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/2.12/bioc/html/methVisual.html
Software package that allows the visualization of DNA methylation data after bisulfite sequencing.
Proper citation: methVisual (RRID:SCR_006705) Copy
http://bioconductor.org/packages/2.12/bioc/html/seqbias.html
Software package that implements a model of per-position sequencing bias in high-throughput sequencing data using a simple Bayesian network, the structure and parameters of which are trained on a set of aligned reads and a reference genome sequence.
Proper citation: seqbias (RRID:SCR_006832) Copy
http://bioconductor.org/packages/2.1/bioc/html/arrayMagic.html
Software providing a collection of utilities for quality control and processing of two-colour cDNA microarray data
Proper citation: arrayMagic (RRID:SCR_010933) Copy
http://www.bioconductor.org/packages/devel/bioc/html/CGHnormaliter.html
Software for normalization and centralization of array comparative genomic hybridization (aCGH) data with imbalanced aberrations. The algorithm uses an iterative procedure that effectively eliminates the influence of imbalanced copy numbers. This leads to a more reliable assessment of copy number alterations (CNAs).
Proper citation: CGHnormaliter (RRID:SCR_002936) Copy
http://www.bioconductor.org/packages/release/bioc/html/chimera.html
A Bioconductor package that organizes, annotates, analyses and validates fusions reported by different fusion detection tools. The current implementation can deal with output from bellerophontes, chimeraScan, deFuse, fusionCatcher, FusionFinder, FusionHunter, FusionMap, mapSplice, Rsubread, tophat-fusion, tophat-fusion-post and STAR. The core of Chimera is a fusion data structure that can store fusion events detected with any of the aforementioned tools.
Proper citation: Chimera (RRID:SCR_002959) Copy
http://www.bioconductor.org/packages/release/bioc/html/triplex.html
Software package that provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many canonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D.
Proper citation: Triplex (RRID:SCR_003061) Copy
http://www.bioconductor.org/packages/release/bioc/html/flowWorkspace.html
Software package that facilitates comparison of automated gating methods against manual gating done in flowJo. This package allows you to import basic flowJo workspaces into BioConductor and replicate the gating from flowJo using the flowCore functionality. Gating hierarchies, groups of samples, compensation, and transformation are performed so that the output matches the flowJo analysis.
Proper citation: flowWorkspace (RRID:SCR_001155) Copy
http://www.bioconductor.org/packages/release/bioc/html/rbsurv.html
Software package that selects genes associated with survival.
Proper citation: rbsurv (RRID:SCR_001175) Copy
http://www.bioconductor.org/packages/release/bioc/html/ARRmNormalization.html
Software package to perform the Adaptive Robust Regression method (ARRm) for the normalization of methylation data from the Illumina Infinium HumanMethylation 450k assay.
Proper citation: ARRmNormalization (RRID:SCR_001292) Copy
http://www.bioconductor.org/packages/release/bioc/html/methylMnM.html
Software package to detect different methylation levels (DMR) that gives the exact p-value and q-value of MeDIP-seq and MRE-seq data for different samples comparison.
Proper citation: methylMnM (RRID:SCR_001289) Copy
http://www.bioconductor.org/packages/release/bioc/html/MergeMaid.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2025. R extension whose functions are intended for cross-study comparison of gene expression array data. Required from the user is gene expression matrices, their corresponding gene-id vectors and other useful information, and they could be "list", "matrix", or "ExpressionSet". The main function is "mergeExprs" which transforms the input objects into data in the merged format, such that common genes in different datasets can be easily found. And the function "intcor" calculate the correlation coefficients. Other functions use the output from "modelOutcome" to graphically display the results and cross-validate associations of gene expression data with survival.
Proper citation: MergeMaid (RRID:SCR_001221) Copy
http://www.bioconductor.org/packages/release/bioc/html/iterativeBMAsurv.html
Software package providing a variable selection method for applying survival analysis to microarray data.
Proper citation: iterativeBMAsurv (RRID:SCR_001254) Copy
http://www.bioconductor.org/packages/release/bioc/html/snpStats.html
Software for classes and statistical methods for large single nucleotide polymorphism (SNP) association studies.
Proper citation: snpStats: SnpMatrix and XSnpMatrix classes and methods (RRID:SCR_001249) Copy
https://bioconductor.org/packages//2.12/bioc/html/exomeCopy.html
Software package for detection of copy number variants (CNV) from exome sequencing samples, including unpaired samples. The package implements a hidden Markov model which uses positional covariates, such as background read depth and GC-content, to simultaneously normalize and segment the samples into regions of constant copy count.
Proper citation: exomeCopy (RRID:SCR_001276) Copy
http://www.bioconductor.org/packages/2.14/bioc/html/SMAP.html
Software package providing functions and classes for DNA copy number profiling of array-CGH data.
Proper citation: SMAP (RRID:SCR_001270) Copy
http://www.bioconductor.org/packages/release/bioc/html/wateRmelon.html
Software package for Illumina 450 methylation array normalization and metrics including 15 flavors of betas and three performance metrics, with methods for objects produced by methylumi, minfi and IMA packages.
Proper citation: wateRmelon (RRID:SCR_001296) Copy
https://www.bioconductor.org/packages//2.10/bioc/html/oneChannelGUI.html
Software library that provides a graphical interface for microarray gene and exon level analysis as well as miRNA/mRNA-seq data analysis. The package was developed to simplify the use of Bioconductor tools for beginners having limited or no experience in writing R code.
Proper citation: oneChannelGUI (RRID:SCR_001325) Copy
http://itb.biologie.hu-berlin.de/~futschik/software/R/cycle/index.html
Software package for the identification of periodically expressed genes using Fourier analysis and the statistical assessment of significance using different background models.
Proper citation: CYCLE (RRID:SCR_001328) Copy
https://www.bioconductor.org/packages//2.12/bioc/html/LMGene.html
Software package for Data Transformation and Identification of Differentially Expressed Genes in Gene Expression Arrays.
Proper citation: LMGene (RRID:SCR_001329) Copy
http://bioinf.wehi.edu.au/affylmGUI/
R software package providing a Graphical User Interface for analysis of Affymetrix microarray data, using the limma package (Linear Models for MicroArray data). While not as powerful as limma to the expert user, it offers a simple point-and-click interface to many of the commonly-used limma and affy functions. You need to have R 1.9.0 or later, Tcl/Tk 8.3 or later (ActiveTcl for Windows, Tcl/Tk Source for Linux/Unix, or X11 Tcl/Tk for MacOSX) and the limma, affylmGUI, and tkrplot R packages. It has been succesfully tested on Windows 2000, Windows XP, RedHat/Fedora Linux, and on Mac OSX with X11.
Proper citation: affylmGUI (RRID:SCR_001320) Copy
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