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http://www.rrcancer.ca/en/publique/accueil
An infrastructure to allow Quebec researchers to have at their disposal tumor banks and the services that support large scale research in genomics and proteomics. The database and the tissue bank of the research network was created to allow rapid access to biological samples and their clinical data. It is spread out over many hospital institutions (in Montreal, Quebec and Sherbrooke). The members of the RRCancer-BTD supply normal, benign and malignant samples from routine surgeries and blood tests. Blood and tissue samples are collected by the provincial biobanks on a regular basis and are coded, classified and stored. The samples can be supplied to a researcher either fresh or frozen or blocks of paraffin or on slices. The sharing of information and biological material is managed according to ethical rules and contributes to increasing the value of research in Quebec. The network has mobilized a significant number of researchers in the area of cancer that unite their efforts to pursue high caliber multidisciplinary research. They are a group of researchers from many different Qu��bec Universities all working in the branch of cancer research. They are located in four hospital centers in Quebec, namely the University of Montreal Hospital Centre (CHUM), the University of Quebec Hospital Centre (CHUQ), the University of Sherbrooke Hospital Centre (CHUS) and the McGill University Hospital Centre (CUSM), as well as in the affiliated research and university centers (Sacr��-Coeur, Maisonneuve-Rosemont and the Montreal Jewish Hospital). The collaborative efforts created and maintained in this network have allowed transfer of knowledge and the sharing of cutting edge technologies. RRCancer favors multidisciplinary cancer research in both fundamental and clinical scopes. The network is based on the desire researchers to work together to prevent cancer and improve therapeutic strategies, all the while continuing the very important task of raining new specialists and graduate students.
Proper citation: Cancer Research Network of the FRSQ (RRID:SCR_004225) Copy
http://www.internationalbiologics.com
International Biologics is a fully accredited American Association of Tissue Banks (����??AATB����??) Tissue Bank and Processing Facility --- Accreditation #00162. It receives 100% of it''s donor tissue from federally licensed Organ Procurement Organizations (OPO����??s) and other AATB accredited donor sources. International Biologics provides multitudinous bone and soft tissue allografts. Clinical applications for these products include: Orthopedic, Spine, Joint Restoration, Oral Maxillofacial, Podiatry, Periodontal, Urology, Trauma The collection and distribution of donated tissue including soft tissue, bone tissue and organ donation of kidneys, livers and hearts (collectively tissue) are controlled by the Government. Organ Procurement Organizations (OPOs) have long been established in every state to recover tissue from donors. Because there is a very short period following death before tissue breaks down rendering it useless for implantation, OPOs maintain round-the-clock presences in hospitals including grief counseling through procurement personnel. OPO tissue is heavily federally regulated and is therefore the most highly sought tissue because it is universally understood to be the safest tissue for transplant. International Biologics has long-term high-volume OPO tissue supply contracts making it one of the largest recipients of cadaveric bone and soft tissue in the world. International Biologics processes its tissue within a state-of-the-art facility located in Scottsdale, Arizona. The facility includes nine -86C ultra low temperature freezers, 14 tray lyophilization, and four validated class 1000 clean rooms including CNC.
Proper citation: International Biologics, LLC (RRID:SCR_004212) Copy
An independent, not-for-profit biobanking and biotechnology foundation designed to facilitate new, high quality medical research. The IBBL collects, stores, and analyzes biological samples and associated data, which are then made available to research organizations investigating new treatments for diseases. It houses a biospecimen collection and biorepository that contains high quality tissues and maintains quality control of the specimens and the clinical data associated with the tissue samples, while maintaining biobanking ethical standards. It also provides biorefinery analyses and research services that can make analytes from tissues (e.g. DNA, RNA and protein), maintains technology for high throughput gene sequencing and gene expression, and conducts biospecimen research. An informatics platform maintains the clinical and biospecimens data in a secure fashion for additional analysis. Samples are collected by IBBL personnel from hospitals in a targeted manner. The IBBL collaborates with research and health organizations in North America, Europe and the Middle East, and with the major international biobanking societies.
Proper citation: Integrated Biobank of Luxembourg (RRID:SCR_004211) Copy
http://www.lifeshareoklahoma.org/
LifeShare Transplant Donor Services of Oklahoma strives to recover healthy, transplantable organs and tissues through careful screening and management of donors to provide the maximum number of lifesaving/life-enhancing organs and tissues for patients awaiting transplantation in Oklahoma. It is committed to providing a better quality of life for those people who require organ or tissue transplantation, while respecting and honoring those families who share the gift of life. LifeShare emphasizes a person''s decision to be an organ and tissue donor and whenever possible will honor the decision of the individual to donate. It works hard to provide education to the state of Oklahoma about organ, eye and tissue donation. Education is provided to medical professionals who identify and care for potential organ and tissue donors, and recognize donation as continuing to care for the patient and their family. LifeShare strongly supports research and development to improve the quality and availability of organs and tissues for transplantation and the success of human transplantation in general. It is also committed to providing support and comfort to grieving families who have suffered great loss.
Proper citation: LifeShare Transplant (RRID:SCR_004298) Copy
Biosample processing, management, storage and retrieval infrastructure that operates on a cost-recovery basis to investigators. Services are available to Research Ethics Board (REB) approved studies. They accept any human tissue from appropriately consented subjects for processing to DNA, RNA, serum, plasma, peripheral blood cells, fixed tissue, and tissue blocks. Once your samples have been collected and processed, CBSR will provide short and long-term sample storage, and retrieval(typically within 24hrs) upon request. Their storage services include robust robotic systems for sample aliquoting, tracking, storage, and retrieval to ensure chain of custody on all samples. Their temperature monitoring system ensures that all samples are maintained at the chosen temperature, and provides regulatory-grade audit trail for all samples.
Proper citation: Canadian Biosample Repository (RRID:SCR_004213) Copy
http://www.ncbi.nlm.nih.gov/tools/epcr/
Web tool that identifies sequence tagged sites (STSs) within DNA sequences. Using e-PCR, you can search for sub-sequences that closely match the PCR primers and have the correct order, orientation, and spacing. The software may also be downloaded to run locally.
Proper citation: e-PCR (RRID:SCR_003082) Copy
http://www.themmrf.org/research-programs/for-academic-researchers/tissue-bank.html
Until recently, a scarcity of high-quality myeloma tissue has posed one of the greatest challenges in advancing myeloma research and drug development. Now, with the successful establishment of the MMRC Tissue Bank, researchers for the first time have access to the critical mass of high-quality tissue needed to rapidly validate novel and combination therapies for myeloma. The MMRC Tissue Bank is the only resource of its kind that integrates myeloma tissue samples with corresponding genomic and clinical data. To date, the MMRC Tissue Bank has accrued more than 2,700 samples with matching peripheral blood samples, with ongoing collection of tissue samples at Member Institutions nationwide. To further accelerate accrual, the MMRC has also launched a direct-to-patient program to enable myeloma patients to donate their tissue to the MMRC Tissue Bank. Notably, all tissue accrued into the MMRC Tissue Bank is uniformly collected and stored in adherence with Good Laboratory Practices (GLP) standards and under the governance of more than 50 standard operating procedures. The MMRC has also established a quality assurance unit that performs weekly internal quality assurance reviews and issues quarterly quality assurance reports. In addition, the MMRC Tissue Bank has been audited twice by external organizations since its inception last year. With these stringent practices in place, the MMRC has ensured that all tissue samples in the MMRC Tissue Bank are of the very highest-quality and, as such, has quickly become the premier resource for industry seeking fresh tissue samples to initiate strong validation work.
Proper citation: Myeloma Tissue Bank (RRID:SCR_004291) Copy
Life Alaska Donor Services is the tissue donation organization serving the state of Alaska, offering the option of donation to families who have suffered a death in Alaska. Life Alaska was established in 1991 as the state''s tissue donation program. Since that time, Life Alaska has had many donors and has supplied thousands of tissues for transplantation to Alaskan patients. Life Alaska works in partnership with the federally designated Organ Procurement Organization in Washington (LifeCenter Northwest) to provide education on tissue and organ donation throughout the state. Tissue donations have taken place across the state, from Barrow to Ketchikan. The age criteria for transplantable tissues and organs are generally from birth to 80 years of age, with patients of any age being candidates for research. Tissues donated to Life Alaska are first offered to Alaskan patients and physicians before being made available outside the state. Organs are shared using the federally mandated national sharing system operated by the United Network for Organ Sharing and are first offered to transplant centers in the Pacific northwest.
Proper citation: Life Alaska Donor Services, Inc. (RRID:SCR_004242) Copy
http://americandonorservices.org/
American Donor Services (ADS) is an independent, non-profit organization specializing in tissue donation. Its mission is to improve lives through the gift of donation. ADS honors the spirit of donation by providing caring support to donor families, employing competent staff, and partnering with organizations that are dedicated to the innovative use of tissue for transplantation and research. We are registered with the Food and Drug Administration (FDA). ADS is also accredited with the American Association of Tissue Banks (AATB) and employs dedicated and experienced leadership and staff to sustain our program. The fundamental objective of ADS is to provide the opportunity of donation to individuals who have designated themselves as a donor and families who have the inclination and the potential to have their loved one become a tissue donor. ADS is dedicated to the cause of all donations and as such will support all other organizations in their parallel undertakings. We are committed to providing the best possible serivce to our Donor Families, Hospitals, Medical Donate Life Examiners, Coroners and Funeral Professionals.
Proper citation: American Donor Services (RRID:SCR_004241) Copy
http://www.bic.mni.mcgill.ca/brainweb/
Database of human brain images derived from a realistic phantom and generated using a sophisticated MRI simulator. Custom simulations may be generated to match a user's selected parameters. The goal is to aid validation of computer-aided quantitative analysis of medical image data. The SBD contains a set of realistic MRI data volumes produced by an MRI simulator. These data can be used by the neuroimaging community to evaluate the performance of various image analysis methods in a setting where the truth is known. The SBD contains simulated brain MRI data based on two anatomical models: normal and multiple sclerosis (MS). For both of these, full 3-dimensional data volumes have been simulated using three sequences (T1-, T2-, and proton-density- (PD-) weighted) and a variety of slice thicknesses, noise levels, and levels of intensity non-uniformity. These data are available for viewing in three orthogonal views (transversal, sagittal, and coronal), and for downloading.
Proper citation: BrainWeb - Simulated Brain Database (RRID:SCR_003263) Copy
Certified by the federal government, LifePoint is the designated Organ Procurement Organization (OPO) for organ recovery services in South Carolina, excepting Aiken and Edgefield counties. LifePoint actively provides organ, tissue and ocular donor services to 62 hospitals throughout the state. We offer professional education about donation to the hospital staff members in order to maximize the amount and quality of donated organs and tissues. LifePoint also helps support and educate families at an emotionally devastating time, so they can make well-informed decisions about organ and tissue donation. Whether they decide for or against donation, our aim is to assure that they will feel they have made the right decision in the months and years to come.
Proper citation: LifePoint, Inc. (RRID:SCR_004235) Copy
http://www.itor-ghs.org/biorepository.php
From the type of mutation causing cancer to specific gene expression levels, genetic biomarkers are becoming an indispensable tool for developing new treatment models for cancer. The ITOR Biorepository Services tissue bank initiatives are critical to the continued development of an organized research infrastructure that will attract leading biotechnology and pharmaceutical companies interested in developing the next generation of cancer therapies. Ultimately, by linking the laboratory and clinical settings through innovative research investigations, USC, Greenville Hospital System University Medical Center, and private partners can identify the most novel ways to find and couple these biomarkers to patient drug trials and eventually, the most effective treatments & cures for cancer. The ITOR Biorepository Services Department ����?����������?? in conjunction with the Greenville Hospital System''s surgical oncologists, pathologists and staff ����?����������?? have developed tissue bank sample processing guidelines for frozen tissue, fresh tissue and peripheral blood and include flash freezing in liquid nitrogen within 15 minutes of harvest to maximize cell viability for basic science research. The department has a dedicated staff, including two research nurses and a data coordinator, which facilitate the logistics of tissue handling and submit outcomes data on participating patients. The ITOR Biorepository staff is in the process of adopting a universal consent for all patients of the Greenville Hospital System to have the option of donating excess tissue for research, should they desire. ITOR of GHS has several tissue-based patient initiatives & programs under development and ongoing. At the forefront of cancer care are two specific programs, Total Cancer Care and Caris Target Now.
Proper citation: ITOR Biorepository Services (RRID:SCR_004191) Copy
http://www.serha.ca/moncton_hospital/subsections/surgery/htm/english/tissue_bank.htm
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. Part of the Surgery Program, The Moncton Hospital''s Tissue Bank is a support service that recovers, processes, stores and distributes bone for transplantation. Approximately 175 surgical bone donors and 25 cadaver donors are received by The Moncton Hospital Tissue Bank each year. The Tissue Bank consolidates the recovery, processing, testing, storage and distribution of tissues for transplantation to: * Improve the health of individuals; * Provide the required tissue to surgeons for their patients; * Provide the highest quality tissue for transplantation; * Ensure the safety, efficacy and economy in all aspects of tissue banking practice; * Ensure that the quantity and range of tissue meets the clinical demand; * Develop and use outcome measures to ensure quality and safety of tissue provided; * Contribute to the development and implementation of national standards; and * Provide a clinical support service to clinicians in order for them to help the patients achieve their optimum level of functioning. While South-East Regional Health Authority has led the province of New Brunswick in organ donation for decades, only in 2002 did the health authority officially embark on working towards achieving accreditation. In October, 2006, the American Association of Tissue Banks awarded the prestigious accreditation to the Dr. Donald MacLellan Tissue Bank, making this the sixth tissue bank in Canada to hold this achievement. This service will enable SERHA to provide better care to New Brunswicker''s in the event of a trauma or the need for reconstructive surgery.
Proper citation: Dr. Donald MacLellan Tissue Bank (RRID:SCR_004145) Copy
https://netbio.bgu.ac.il/labwebsite/software/responsenet/
WebServer that identifies high-probability signaling and regulatory paths that connect input data sets. The input includes two weighted lists of condition-related proteins and genes, such as a set of disease-associated proteins and a set of differentially expressed disease genes, and a molecular interaction network (i.e., interactome). The output is a sparse, high-probability interactome sub-network connecting the two sets that is biased toward signaling pathways. This sub-network exposes additional proteins that are potentially involved in the studied condition and their likely modes of action. Computationally, it is formulated as a minimum-cost flow optimization problem that is solved using linear programming.
Proper citation: ResponseNet (RRID:SCR_003176) Copy
Donor Alliance is one of 58 not-for-profit organ recovery organizations federally designated by the U.S. Department of Health & Human Services to facilitate the donation and recovery of organs for people needing transplants. Additionally, Donor Alliance is a recognized leader in facilitating the donation and recovery of transplantable tissues in Colorado and most of Wyoming. Our goal is to save the lives of people in need. To achieve this, Donor Alliance employs effective family approach and recovery programs in more than 100 hospitals in Colorado and Wyoming. Additionally, Donor Alliance dedicates time, funding and effort toward increasing the number of registered organ and tissue donors through active public awareness and educational programs and grassroots public relations campaigns.
Proper citation: Donor Alliance (RRID:SCR_004265) Copy
A non-profit organization dedicated to saving lives through organ and tissue donation in the seven-county greater Los Angeles area. With more than 200 hospitals, 12 transplant centers and a diverse population of 19 million, OneLegacy is the largest organ and tissue recovery organization in the world. OneLegacy saves and heals lives through organ, eye and tissue donation, comforts the families we serve, and inspires our communities to Donate Life. With each day comes a chance for people to say yes to donation and help those on the other side of the bridge, one legacy at a time.
Proper citation: OneLegacy (RRID:SCR_004148) Copy
http://www.startthecure.com/clinical_tumor_bank.php
Biospecimen repository for tumor specimens, available to all researchers actively engaged in cancer research whether they are in University, Academic, or Pharmaceutical industry, with a goal to accelerate the discovery and development of new agents for the treatment and cure of cancer. The START tumor bank was created to make tumor tissue gifted by patients receiving care or treatment at The START Center available to all researchers involved in developing a better understanding of the biology of cancer or those engaged in the discovery of new therapies. The START Tumor Bank is a department within the PK Department and handles skin and tumor biopsies required by clinical trial protocols. A member of the PK Department is present during biopsy procedures for immediate processing of the sample for the trial. Additionally, the Tumor Bank collects and banks the tumor tissues of patients who consent. This tissue is then stored for future use by researchers developing new therapies.
Proper citation: START Tumor Bank (RRID:SCR_004258) Copy
http://www.mknt.hu/sites/default/files/NEPSYBANK_0.doc
The Hungarian Society of Clinical Neurgenetics established a nationwide collaboration for prospective collection of human biological materials and databases from patient with neurological and psychiatric diseases. The basic triangle of the NEPSYBANK is the sample, the information and the study management. The present participants of the NEPSYBANK are the Department of Neurology and Psychiatry of the four Medical Universities (in Budapest, Debrecen, Pecs, Szeged) and the National Institute of Psychiatry and Neurology in Budapest. The NEPSYBANK is a disease based biobank collecting both phenotypical and environmental data and biological materials such as DNA/RNA, whole blood, plasma, cerebral spinal fluid, muscle / nerve / skin biopsy, brain, and fibroblast. The target of the diseases is presently (Phase I): stroke syndromes, dementias, movement disorders, motoneuron diseases, epilepsy, multiple sclerosis, schizophrenia, alcohol addiction. In the near future (Phase II.) it is planned to enlarge the scale with headaches, disorders of the peripheral nerves, disorders of neuromuscular transmission, disorders of skeletal muscle, depression, anxiety. DNA/RNA is usually extracted from whole blood, but occasionally different tissues such as muscle, brain etc. can be used as well. The extracting procedures differ among the institutes, but in all cases the concentration and the quality of the DNA/RNA must be registered in the database. Participating institutional biobanks have committed themselves to follow common quality standards, which provide access to samples after prioritization on scientific grounds only. In every case the following data are registered. 1. General data: main bank categories, age, sex, ethnicity, body height, body weight, economic stats, education, type of place of living, marital status, birth complications, alcohol, drugs, smoking. 2. Sample properties (sample ID, type of sample, date of extraction, concentration, and level of purity). General patient data as blood pressure, heart rate, internal medical status, ECG, additional diseases. Disease specific question e.g. in schizophrenia the diagnosis after DSMIV and ICD 10, detailed diagnostic questions after both classification, detailed psychiatric and neurological status, laboratory findings, rating scales, data of neuroimaging, genetic tests, applied medication (with generic name, dose, duration), adverse drug effects and other treatments. The Biobank Information Management System (BIMS) is responsible for linkage of databases containing information on the individual sample donors. If you want to have samples from the NEPSYBANK an application must be submitted containing the following information: short research plan including aims and study design, ethic application with a positive decision, specific demands regarding the right of disposition, agreements with grant organizations which regulate immaterial property, information about financing (academic grants, support from industry). All participants have the right to withdraw their samples through a simple order.
Proper citation: Hungarian Neurological-Psychiatric Biobank (RRID:SCR_003715) Copy
http://www.lifenethealthflorida.org/index.html
Founded in 1982 and headquartered in Virginia Beach, VA, LifeNet Health Inc., is a leading biomedical alloengineering organization and organ and tissue donation agency whose mission is saving lives and restoring health. LifeNet Health of Florida is a fully owned subsidiary dedicated to the recovery of tissue in Northern Florida, improving the awareness of tissue donation and educating the public about donation in the Northern Florida Community. Our mission is to improve upon the awareness of tissue donation within the community as well as to provide human tissue for transplant. We strive to give back to the community by providing an extensive public education program regarding donation, as well as being involved and making contributions that we feel will benefit the local community as a whole. Our efforts with total quality management have solidified our belief that LifeNet Health of Florida, Inc., must be driven by excellence in service and uncompromising quality. By the continuous improvement of processes and services leading to a better understanding of the entire donor process for both hospital personnel and members of our community.
Proper citation: LifeNet Health of Florida (RRID:SCR_004565) Copy
The Cancer Diagnosis Program of the National Cancer Institute (NCI) initiated the Cooperative Human Tissue Network (CHTN) in 1987 to provide increased access to human tissue for basic and applied scientists from academia and industry to accelerate the advancement of discoveries in cancer diagnosis and treatment. This unique resource provides remnant human tissues and fluids from routine procedures to investigators who utilize human biospecimens in their research. Unlike tissue banks, the CHTN works prospectively with each investigator to tailor specimen acquisition and processing to meet their specific project requirements. Because the CHTN is funded by the NCI, the CHTN is able to maintain nominal processing fees for its services. The CHTN is comprised of five adult divisions and one pediatric division. Each of the adult divisions coordinates investigator applications/requests based upon the investigator's geographic location within North America. The Pediatric Division manages all investigators who request pediatric specimens only. The CHTN divisions share coordination for requests from outside North America. The CHTN divisions work both independently with individual investigators and together as a seamless unit to fulfill requests that are difficult to serve by any single division. The CHTN's unique informatics system allows each division to effectively communicate and network the needs of its investigators to all CHTN divisions. The Network as a whole can then help fulfill an investigator's request. Biospecimens from surgeries, autopsies and other routine procedures: Malignant, Benign, Diseased, Normal, Biofluids (urine, serum, plasma, buffy coat) High quality specimens at LOW processing fees: Fresh, Frozen, Floating in fixative, RNAlater, Paraffin embedded or and/or unstained slides, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Cooperative Human Tissue Network (RRID:SCR_004446) Copy
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