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https://med-upenn.corefacilities.org/sc/4405/crispr-cas9-mouse-targeting-core/?tab=about

Core facilitates use of CRISPR/Cas9 genome editing technology to generate novel mouse genetic tools.

Proper citation: University of Pennsylvania Perelman School of Medicine CRISPR Cas9 Mouse Targeting Core Facility (RRID:SCR_022378) Copy   

•   Source: SciCrunch Registry

https://www.sbpdiscovery.org/biomedical-research/shared-resources/proteomics

Facility provides mass spectrometry based proteomics services with methods tailored to needs of scientific investigators for routine mass spectrometric analysis of peptides and proteins, identification of novel proteins, characterization of post translational modifications, and quantitative proteomics analysis of simple to complex biological samples. Core identifies, validates and develops new methods designed for characterization and identification of biologically important proteins. Supports users with software applications and development, data analysis and experimental design of proteomics studies. Expands its capabilities in large scale differential proteomics analysis and phosphoproteomics for unbiased discovery of potential biomarkers and mapping protein profiles.

Proper citation: Sanford Burnham Prebys Medical Discovery Institute Proteomics Core Facility (RRID:SCR_022225) Copy   

•   Source: SciCrunch Registry

https://www.research.colostate.edu/csudronecenter/

Offers consultation on drone systems, UAS project guidance, UAS piloting, assistance with UAS pilot training, liaison and navigation of FAA regulations, and as point of contact for UAS inquiries from outside the University. Assists in authorizing flight requests at CSU and managing Christman Airfield use for drone flights. Maintains fleet of sUAS aircraft and air borne sensors.

Proper citation: Colorado State University Drone Center Core Facility (RRID:SCR_022003) Copy   

•   Source: SciCrunch Registry

https://www.research.colostate.edu/samdcore/

Core facility that enables research and development programs by providing expertise and access to equipment for synthesis, processing and testing of materials. Support and enables materials research and education by offering range of materials synthesis, processing, and testing equipment, combined with individualized training and staff expertise.

Proper citation: Colorado State University School of Advanced Materials Discovery Core Facility (RRID:SCR_022002) Copy   

•   Source: SciCrunch Registry

https://www.research.colostate.edu/fcf/

Provides access to flow cytometry and cell sorting instrumentation, services, and expertise for all researchers at Colorado State University. FCF includes spectral flow cytometers Cytek Aurora which enables users to perform more than 25 markers in a sample. FCF also has 10X Genomics chromium controller used to barcode single cells to perform single cell sequencing. Offers data analysis of these complex flow cytmetry and single cell sequencing samples using R programming or bash shell based pipelines.

Proper citation: Colorado State University Flow cytometry, cell sorting, and single cell analysis Core Facility (RRID:SCR_022000) Copy   

•   Source: SciCrunch Registry

https://www.sc.edu/study/colleges_schools/pharmacy/research_and_practice/research_centers_and_facilities/microarray_core_facility/index.php

Services include RNA quality control, amplification and labeling, array hybridization, scanning and data analysis, assisting customers in design and performance of microarray experiments, using Agilent (pre-made and custom) and Affymetrix arrays. Provides support for quantitation and quality assessment of DNA, RNA and protein on Agilent 2100 Bioanalyzer. Provides training and support for Agilent and Affymetrix Hybridization oven users. Provides support for microarray scanning and for data analysis with variety of software packages for both Agilent and Affymetrix platforms.Quantity and quality of your RNA, DNA, proteins and cells are determined with help of Agilent 2100 Bioanalyzer.

Proper citation: University of South Carolina at Columbia College of Pharmacy Microarray Core Facility (RRID:SCR_022211) Copy   

•   Source: SciCrunch Registry

http://uoft.me/AIMS

Core mass spectrometry facility located in Department of Chemistry, University of Toronto, which houses several mass spectrometers. Services include:High resolution, accurate mass determinations of small molecules via EI, ESI and DART ionization;Mass determinations of intact peptides and proteins via ESI-QTOF-MS and MALDI-MS; HPLC-MS/MS analysis of protein digests via ESI-QTOF-MS; Quantitative analysis via HPLC-MS/MS using QqQ instrumentation.

Proper citation: University of Toronto Advanced Instrumentation for Molecular Structure Mass Spectrometry Laboratory Core Facility (RRID:SCR_022210) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/cores/#Xray

Facility encompasses X-ray diffraction, providing crystallographic, structural, and compositional information, and X-ray tomography, enabling nondestructive tomographic imaging and grain reconstruction used to distinguish between phases, identify defects, and provide 3D crystallographic grain reconstructions.

Proper citation: Colorado School of Mines Shared Instrumentation Facility X-ray Diffraction and Computed Tomography Core Facility (RRID:SCR_022053) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/cores/#MT

Provides variety of monotonic, fatigue, temperature, and strain measurement capabilities. These capabilities cover wide range of load capacities and resolutions, displacement rates, loading configurations, and custom fixturing.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Mechanical Testing Core Facility (RRID:SCR_022051) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/corefacilities/cryo-em

Provides equipment, expert technical assistance and image analysis expertise to enable all aspects of macromolecular structure determination by single particle cryo-electron microscopy.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource CryoEM Core Facility (RRID:SCR_021999) Copy   

•   Source: SciCrunch Registry

https://micron.hms.harvard.edu/

Light microscopy core is open to HMS researchers, including Affiliated hospitals. Supports imaging modalities ranging from wide field, TIRF, spinning disk and single point scanning confocal, multiphoton, FLIM and supper resolution. Microscopes are embedded within Departments of Microbiology, Immunology, and Genetics, housed in five microscope rooms on five floors of NRB and HIM.

Proper citation: Harvard Medical School Microscopy Resources On the North Quad Core Facility (RRID:SCR_022209) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/corefacilities/nmr/home

Core enables study of biomolecular structure, dynamics and interactions in solution at atomic level. Provides NMR spectrometers from 600 MHz to 900 MHz equipped for biomolecular NMR studies. Equipment include 900 MHz Bruker Avance Neo with Oxford 21 T magnet - TCI Cryoprobe 600 MHz Bruker Avance Neo with Bruker Sample Jet (2024) - TCI Cryoprobe 600 MHz Varian Inova with HCN cryoprobe.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource NMR Core Facility (RRID:SCR_021997) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/corefacilities/x-ray-crystallography

Core performs all aspects of structure determination of large biomolecules such as proteins and nucleic acids including macromolecular crystallization, crystal screening, molecular structure and model building.

Proper citation: University of Colorado Anschutz Medical Campus Cancer Center Structural Biology Shared Resource X Ray Crystallography Core Facility (RRID:SCR_021998) Copy   

•   Source: SciCrunch Registry

https://www.biomedicas.unam.mx/servicios/unidad-de-microscopia/

Core is specialized in stereology techniques, live cell imaging, CLSM (confocal microscopy), and STORM. Provided instruments include CONFOCAL microscopes Zeiss LSM 5 Pascal, Olympus BX51-WI,Olympus IX71 inverted microscope, Nikon Labophot-2 microscope,Nikon Optiphot 2 microscope.

Proper citation: National Autonomous University of Mexico Microscopy Core Facility (RRID:SCR_022204) Copy   

•   Source: SciCrunch Registry

http://www.cemib.unicamp.br

Core produces mice and rats for biomedical research. Provides services for customers are researchers from Unicamp and other Institutions from Brazil.

Proper citation: State University of Campinas Multidisciplinary Center for Biological Investigantion on Laboratory Animals Science Core Facility (RRID:SCR_022203) Copy   

•   Source: SciCrunch Registry

https://vtpb.tamu.edu/flow-cytometry/

Provides flow cytometry experimental design, data collection, data analysis and cell sorting services; training for flow cytometers, imaging flow cytometer, and data analysis using IDEAS and FlowJo software;staff assisted flow cytometry and imaging flow cytometry data acquisition, cell sorting, and data analysis, experimental design and consultation services. FCF currently has Beckman Coulter Moflo Astrios cell sorter, Luminex/Amnis Image Stream X Mark II, Luminex/Amnis Cell Stream, and Becton Dickinson Accuri C6 flow cytometer. Astrios cell sorter is housed in ClassII BSC and has 3 lasers (405nm, 488nm, 642nm) and 11 detectors and can sort up to 6 populations simultaneously. Image Stream X Mark II is equipped with 20x, 40x, 60x objectives, 4 lasers (405nm, 488nm, 561nm, 642nm), 10 detection channels, EV mode for small particle detection, and an autosampler.Cell Stream is equipped with 3 lasers (405nm, 488nm, 642nm), 13 detection channels, EV mode for small particle detection, and autosampler. Accuri C6 is equipped with 2 lasers (488nm, 642nm), and 4 detection channels.

Proper citation: Texas A and M University College of Veterinary Medicine and Biomedical Sciences Flow Cytometry Core Facility (RRID:SCR_022169) Copy   

•   Source: SciCrunch Registry

https://mcf.tamu.edu/

Core provides access to instrumentation essential for studies of surface and interfacial properties of materials, such as ion and electron based spectroscopies, electron, optical and scanning probe microscopies. Core provides training to students and faculty on instrumentation as well as consolation of measurements needs and data interpretation, supports educational activities involving lab tours, workshops, hands on demonstrations, outreach and broader impact related activities through our open house and lunchtime seminar series.Supports collaborative research projects with outside industrial users.

Proper citation: Texas A and M University Materials Characterization Core Facility (RRID:SCR_022202) Copy   

•   Source: SciCrunch Registry

https://genome.med.harvard.edu/

Provided core services include Sanger DNA Sequencing, Next Generation DNA Sequencing (Four Illumina MiSeqs, four Illumina NextSeq 500s and one Illumina NovaSeq 6000),Next Generation Automated Library Sample Prep (Perkin Elmer Sciclone Genomic, ChIP, RNAseq and other methods), Single Cell DNA and RNA-Seq (10X Genomics Chromium), Bioanalyzer Analysis DNA and RNA (Two Agilent 2100 BioAnalyzers and two Agilent 2200 TapeStations), Qiagen Qiacube Automated DNA / RNA Prep (single to multiple samples), Oligonucleotide Ordering (IDT Portal), Reagents and Supplies Ordering (multiple vendors / products). Facility web based Laboratory Information Management System provides users with access to order services and supplies as well as retrieve data and review and pay invoices all online.

Proper citation: Harvard Medical School Biopolymers Core Facility (RRID:SCR_007175) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/histopathology-core

Provides routine and customized histology and immunohistochemistry services critical for progress of biomedical research.

Proper citation: OHSU Histopathology Shared Resource Core Facility (RRID:SCR_009977) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/gene-profiling-shared-resource

Full service genomics facility providing research scientists and clinicians with services for RNA expression profiling, DNA variation analysis, and nucleic acid extraction.

Proper citation: OHSU Gene Profiling Shared Resource Core Facility (RRID:SCR_009975) Copy   

•   Source: SciCrunch Registry