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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.umassmed.edu/cancercenter/tissuebank/index.aspx
The UMass Cancer Center Tissue and Tumor Bank is a dynamic tissue procurement service: Collection, Storage, Annotation, and Distribution of Human Biologic Specimens. Our goal is to facilitate basic science, clinical research and translational studies by providing researchers with the ability to obtain and study human tissues using a dynamic collection, storage, annotation, and distribution service. * Fresh, diseased tissue is collected and processed immediately after surgery. ** When possible, surrounding healthy tissue is collected as a matched normal control. ** Anonymous, de-identified clinical and pathologic data are linked to the specimens in a secure database. * Bone marrow and blood specimens are collected and available as fresh cell isolates, frozen cell isolates or unprocessed. * A variety of services are available including routine histology, fresh tissue for cell culture, frozen sections, as well as DNA and RNA extraction. * Specific study needs can be met. * Consultation during study design is available and recommended. Contact Us * Assistance in the IRB approval process is offered. ** New: IRB approval is required only if you need identifiable private clinical information and/or patient follow-up for your study. The UMass Cancer Center Tissue and Tumor Bank is an open access biorepository. Specimens are available to investigators both internal and external to UMass. The Tumor Bank ships specimens to researchers worldwide. Please contact us to determine if we have specimens that meet your research needs.
Proper citation: UMass Cancer Center Tissue and Tumor Bank (RRID:SCR_004447) Copy
https://htrn.osu.edu/Services/Biorepository/Pages/default.aspx
The HTRN biospecimen bank is comprised of samples for the Ohio State University Cancer and Leukemia Group B Pathology Coordinating Office (CALGB-PCO) and the Ohio State University Midwestern Division of the Cooperative Human Tissue Network (CHTN). The CALGB-PCO banks biospecimens donated by patients enrolled in clinical trials. Samples can include tumor and normal tissue, plasma, serum, whole blood and white blood cells and urine. All of these samples are used later in correlative studies. The Midwestern Division of the CHTN stores a temporary biospecimen bank of tumor and normal tissue, tissue slides and paraffin embedded tissue blocks for research investigators throughout the country and Canada who are trying to find a cure for cancer. As part of the HTRN biospecimen bank, a Rees Scientific equipment monitoring system helps to secure the integrity and quality of samples stored in the biorepository. Scientific research within the HTRN is currently underway to determine the best methods in tissue storage for long term use. The NCI First-Generation Guidelines for NCI-Supported Biorepositories and the NCI Best Practices for Biospecimen Resources are continuously reviewed and adapted by the HTRN.
Proper citation: Ohio State Biorepository (RRID:SCR_004714) Copy
Established in 1990 as a long term storage cryobank, ReproTech, Ltd. is dedicated to offering safe and effective shipment and long term storage of reproductive tissue that has been originally cryopreserved at another laboratory or cryobank. It is the intent of RTL to provide the physician and client depositors with quality services that fully comply with industry and government Standards and/or Regulations. Our Locations: Florida, Minnesota, Nevada, US Network Administration ReproTech, Ltd. (RTL) is a one-stop resource specializing in effective solutions to the challenges faced in today''s ever changing field of Reproductive Medicine. ReproTech''s experienced staff provides expert consultation services for long term storage of reproductive tissues and donor program management to assist in compliance with regulatory agencies.
Proper citation: ReproTech, Ltd. (RRID:SCR_004319) Copy
http://www.dciinc.org/donors.php
An affiliation of organ and tissue recovery organizations across the United States that is committed to saving and improving lives by connecting one life to another through donation and transplantation. DCI Donor Services (DCIDS) supports families who have sustained the loss of a loved one by providing an opportunity for organ, eye and tissue donation and by facilitating the recovery and transplantation of these gifts to help others in need. They also provide after-care support to donor families while at the same time working to inspire universal acceptance of donation throughout the hospitals and communities we serve to ensure every person in need receives the Gift of Life.
Proper citation: DCI Donor Services (RRID:SCR_004554) Copy
The Southeast Tissue Alliance recovers tissues and provides them to leading tissue processing companies. One of the most important aspects of this process is ensuring that donor families understand tissue donation and are fully supported as they make the gifts that change the lives of others. To promote tissue donation, we also work throughout the community to increase awareness, educate health professionals and further donation-related research. The Southeast Tissue Alliance is accredited by the American Association of Tissue Banks, which ensures that our services are of the highest quality and are provided in the most professional manner.
Proper citation: Southeast Tissue Alliance, Inc. - SETA (RRID:SCR_004675) Copy
https://conticabase.sarcomabcb.org/
This database contains anonymized information describing the tumor, treatment and follow-up as well as tumor sample availability and molecular biology analyses for mesenchymal tumors except GIST and bone tumors. The query tool allows users to ask questions about the overall content of the database in order to evaluate the feasibility of specific collaborative studies. We hope this database will become an important tool for increasing our knowledge on these rare tumors and for developing joint research programs. The tool can be used as a local center database thanks to its rules for access to patient data and material. Conticabase currently contains the following data from 31 out of the 48 registered centers (Last modification on 28/03/2012): * 11518 Patients * 11562 Tumors * 13897 Samples (13636 Paraffin and 5773 Frozen) Use of conticabase data At anytime, a data manager can export data of patients from his (her) Centre or group according to his (her) level of rights. To obtain data from another Centre, a partner should ask the coordinator of the corresponding Centre for these data. To use data for a cooperative study, a member should write a short text describing the project and send it to partners of interest. Each partner may decide whether to participate or not and therefore, whether to send or not the corresponding data to the project leader. In the event that the data from the conticabase result in a publication, acknowledgement is required. Use of tumour material entered in the ConticaBank To obtain material from another Centre for a cooperative study, a partner should write a short text describing the project and send it to the partners of interest. Each partner may decide whether to participate or not and, therefore, whether to send or not the corresponding material to the project leader. In the event that the material used result in a publication, acknowledgement is required.
Proper citation: Conticabase - European Sarcoma Database and Tumour Bank (RRID:SCR_004832) Copy
LifeCenter Organ Donor Network, A Donate Life Organization, encourages and coordinates the donation of human organs and tissues for transplantation. In 1981 LifeCenter began operating as an independent, not-for-profit organ procurement organization (OPO) with a mission to save, enhance and change lives through organ and tissue donation. LifeCenter is accredited by the Association for Organ Procurement Organizations (AOPO) and the American Association of Tissue Banks (AATB), and has been approved and designated by the Centers for Medicare and Medicaid Services (CMS) as the primary OPO serving eight counties in Southwestern Ohio, six counties in Northern Kentucky and two counties in Southeastern Indiana. LifeCenter is an institutional member of the United Network for Organ Sharing (UNOS) and follows all the guidelines for organ sharing. The population of LifeCenter''s service area is approximately two million people. Within this area there are 30 hospitals that LifeCenter works with to facilitate and coordinate organ and tissue donation. The clinical staff provides 24-hour service for referrals, case management, recovery and organ placement. Our education staff provides programs for schools, civic and community groups, religious institutions and healthcare professionals. Additional services offered by LifeCenter include bereavement services for donor families, volunteer opportunities, and donor drives for area businesses and organizations that facilitate the enrollment of donors.
Proper citation: LifeCenter Organ Donor Network (RRID:SCR_004794) Copy
http://www.kamtekinc.com/Repository.php
Biorepository promoting the safe handling, receipt, processing, storage, inventory control, packaging and distribution for all types of infectious and non-infectious biological specimens and reagents. The facility houses ultra-low mechanical freezers, vapor-phase liquid nitrogen freezers and mechanical walk-in freezer and cold rooms. A multi-purpose computerized security system provides around-the-clock secure access, intrusion and fire detection, and electronic monitoring of all freezers and critical building functions. In the past, KamTek managed NIH-NIAID Reference reagent Repository that stored and distributed over 2000 different reagent products including antisera against a wide variety of viruses and other infectious organisms, as well as viral antigens, allergenic, mycoplasma, and immunologic reagents. The NIAID Repository was designated World Health Organization (WHO) Collaborating Center for Antiviral Drugs and Interferon and responsible for the international distribution of the WHO Interferon reference standards. In addition, other government agencies and private sector clients use our repository and there is provision to accommodate new clients as well. BIO-SPECIMEN REPOSITORY SERVICES: * Bio-specimen Acquisition * Bio-specimen Processing * Cryo-preservation * Cryo-storage and Maintenance of Bio-Repository * Shipments * Inventory of stored biological samples * Database management of inventory for each project
Proper citation: KamTek Biorepository (RRID:SCR_004311) Copy
http://angioma.org/pages.aspx?content=105&id=92
Angioma Alliance has established a DNA/Tissue Bank and matching clinical database for cerebral cavernous malformations (CCM, cavernous angioma, cavernoma). Our goal is to create the world''s largest collection of CCM genetic samples with matching clinical data to be used as a resource to drive research. We are recruiting individuals with a history of cerebral cavernous malformations to participate in the study. Qualified participants donate a blood sample and complete a comprehensive questionnaire or interview. Blood donation kits will be sent in the mail for participants to take to their doctor, clinic or blood draw center to have their blood drawn. The kit is then mailed to a private lab where the sample is processed. If a surgery is scheduled, the Angioma Alliance DNA/Tissue Bank will work with the participant, the surgeon, and the hospital to coordinate tissue donation. If surgery scheduling allows, dry ice will be shipped to the hospital facility along with a tissue collection kit for use and return to the private lab. The Angioma Alliance DNA/Tissue Bank will attempt to acquire Institutional Review Board approvals at facilities where this is required. The Angioma Alliance BioBank will follow up with participants on a yearly basis to update their clinical information. If the participant has not already had documented genetic testing, we will test their DNA sample for possible CCM1, CCM2, or CCM3 mutation or CCM2 exon 2-10 deletion. If additional causative genes are identified for the illness, we will also test for mutations on these. Participants will not be informed of the results of testing, but if a mutation or deletion is found, they will be informed that results can be released to a diagnostic laboratory in order to obtain follow-up confirmatory clinical diagnostic testing. This could mean a substantial cost savings to the patient whose insurance does not cover genetic testing or who is uninsured. All researchers requesting the use of DNA and/or Tissue samples from Angioma Alliance must complete an application form and material transfer agreement.
Proper citation: Angioma Alliance DNA/Tissue Bank and Patient Registry (RRID:SCR_004390) Copy
http://www.ihop-net.org/UniPub/iHOP/
Information system that provides a network of concurring genes and proteins extends through the scientific literature touching on phenotypes, pathologies and gene function. It provides this network as a natural way of accessing millions of PubMed abstracts. By using genes and proteins as hyperlinks between sentences and abstracts, the information in PubMed can be converted into one navigable resource, bringing all advantages of the internet to scientific literature research. Moreover, this literature network can be superimposed on experimental interaction data (e.g., yeast-two hybrid data from Drosophila melanogaster and Caenorhabditis elegans) to make possible a simultaneous analysis of new and existing knowledge. The network contains half a million sentences and 30,000 different genes from humans, mice, D. melanogaster, C. elegans, zebrafish, Arabidopsis thaliana, yeast and Escherichia coli.
Proper citation: Information Hyperlinked Over Proteins (RRID:SCR_004829) Copy
http://www.pxe.org/blood-tissue-bank
The PXE International BioBank and Clinical Data Registry is the centralized sample repository and registry for pseudoxanthoma elasticum (PXE). It enables translational research and treatment discovery. PXE International, Inc. holds the world''''s largest collection of blood and tissue from people affected by PXE and their families. It is the only centralized repository for PXE samples in the world. The PXE International BioBank has tens of thousands of samples, including DNA, tissue from every organ in the body, full body donations postmortem, and many special samples such as eyes, urine, breast tumor tissue and so on. The PXE International Clinical Data Registry ties the biological samples to the clinical record and stores self reported data (surveys and questionnaires), medical records (from any specialist), images (CT scans, MRIs and so on) and anything else that can be scanned or typed in. We are using these samples for genetic research ������?? examining the many mutations, the effect of the mutations on the cell and the future of possible interventions. PXE International established the PXE International Blood and Tissue Bank to make certain that your privacy and confidentiality are protected and your samples are available to any approved research project. Researchers interested in either donating PXE DNA, tissue and cell lines or in applying to use material from the bank should call 202.362.9599 or email Sharon Terry.
Proper citation: PXE International Registry and BioBank (RRID:SCR_004668) Copy
http://pathology.duke.edu/biospecimen-repository-processing-core
The Duke Institute for Genome Sciences & Policy (IGSP), in partnership with the Duke University School of Medicine Research Foundation and Department of Pathology (SOMRF), has established the Duke IGSP Biospecimen Repository as a centralized and accessible biological resource for Duke Investigators and research programs. The Repository is a standardized, regulatory-compliant and privacy protected repository for fluid and tissue biospecimens, and enables Duke investigators to reduce costs, and eliminate redundancies and significant risks associated with alternative biobanking practices, while facilitating integration of clinical trials and translational research programs with molecular profiling technologies. In order to ensure sample and data integrity and comparability, the Biorepository is developing, evaluating, and implementing evidence-based biobanking ''best practices''. Centralization of activities to a dedicated and expert staff and facility allows small and large research programs to reduce costs through elimination of redundancies and achieving efficiencies and economies of scale. The Duke-IGSP Biorepository is committed to ensuring appropriate consent, approved use, and protection of privacy through compliance with HIPAA regulations and IRB guidelines. The Duke-IGSP Biospecimen Repository will facilitate the integration of clinical research programs with molecular profiling technologies, enabling large-scale ''omic'' research programs that will inform and drive the development of new generations of targeted diagnostics, therapies, and preventions, which in turn will transform clinical outcomes.
Proper citation: Duke Biospecimen Repository (RRID:SCR_004306) Copy
Through the South Dakota Lions Eye Bank, donors can provide the gift of sight and health through the donation of bone, connective tissue, heart valves, veins, skin, and corneas. The option of donation is available to both men and women, up to the age of 95. Since 1990, the South Dakota Lions Eye Bank has restored sight to over 5500 people world wide. In recent statistics the South Dakota Lions Eye Bank has transplanted 2217 corneas since 2001; 1237 transplanted in the United States and 980 transplanted overseas. It is the fondest hope of the South Dakota Lions Eye Bank that you will become an eye, tissue and organ donor and pass along to someone the greatest gift of all, Life.
Proper citation: South Dakota Lions Eye Bank (RRID:SCR_004465) Copy
http://www.bio-vault.com/humantissuebank
Private human tissue processing and storage bank in the UK based in Plymouth on the medical campus of Derriford Hospital, Europe''s 4th largest teaching hospital. The company was set up to serve the UK and private health sectors looking to outsource the processing and storage of human tissue to an accredited, trusted and experienced expert. Storing for human application, they now process and store human tissue for organizations all over the world, including the Plymouth Hospitals NHS Trust. They are also the only private tissue bank of any true scale in the UK with the ability to store well over 1 million human tissue samples on one site. BioVault has achieved a number of accreditations and forged relationships with numerous bodies since 2002, all designed to test the robustness of our internal procedures and reassure clients they are being given the highest levels of quality and service. Many of BioVault''s pioneering systems have been designed to exceed the criteria set out by the Human Tissue Authority (HTA) with whom we work closely. The HTA is the competent authority under the European Tissue and Cell Directive and sets the standards for regulating human tissue application establishments.
Proper citation: BioVault (RRID:SCR_004339) Copy
https://www.ucl.ac.uk/biobank/physicalbloom
The UCL/UCLH Biobank for Studying Health and Disease has been primarily established to support the Research Programme and scientific needs, of the Pathology Department UCLH & the UCL Cancer Institute. The establishment of the core programme enables a centralised approach to the management and integration of all research groups working within these institutions, providing appropriate structure and support. The biobank has policies and guidelines to guarantee compliance with HTA legislation and to ensure quality standards will be maintained. The biobank stores normal and pathological specimens, surplus to diagnostic requirements, from relevant tissues and bodily fluids, as well as human tissue used in xenograft experiments. Stored tissues include; snap-frozen or cryopreserved tissue, formalin-fixed tissue, paraffin-embedded tissues, and slides prepared for histological examination. Tissues include resection specimens obtained surgically or by needle core biopsy. Bodily fluids include; whole blood, serum, plasma, urine, cerebrospinal fluid, milk, saliva and buccal smears and cytological specimens such as sputum and cervical smears. Fine needle aspirates obtained from tissues and bodily cavities (eg. pleura and peritoneum) are also collected. Where appropriate the biobank also stores separated cells, protein, DNA and RNA isolated from collected tissues and bodily fluids described above. Some of the tissue and aspirated samples are stored in the diagnostic archive.
Proper citation: UCL/UCLH Biobank for Studying Health and Disease (RRID:SCR_004610) Copy
http://www.biobanque-picardie.com/index_En.php
A secure repository of biological samples and data dedicated for medical and research purposes. These biological samples are linked to consenting patient relative data. Biobanque de Picardie provides quality and traceability services for establishment, conservation and use of biological samples collections. It houses collections of human tissue in a variety of areas of disease. Samples are used in basic research and translational studies, physiopathology of diseases and identification of new diagnostic, and as prognostic or therapeutic biomarkers. Biobanque de Picardie also develops healthy or pathological human primary stem cell banks, such as: mesenchymal stem cells in umbilical cord (HUC-MSC), primary hepatocytes (HPH), peripheral blood mononuclear cells (PBMC), and fibroblasts. Biological samples are stored at - 80 degrees C in electric freezers, at - 196 degrees C in liquid nitrogen or -130 degrees C in nitrogen vapor.
Proper citation: Biobanque de Picardie (RRID:SCR_004731) Copy
Science Care''s whole body donation program supports medical research, training and professional education, which provides enormous benefits to humankind. Given the increasing advancements in medical technologies, donation is of greater importance than ever. A life-affirming choice, donation is also a highly individual decision. In every way possible, Science Care honors that decision by adhering to the strictest guidelines and providing the most compassionate care. Science Care was founded in 2000 with the vision to become the world''s leading whole body donor program. Under the leadership of James Rogers, Founder and CEO, Science Care has accelerated research on many fronts leading to the development of new medical devices and safer, more effective treatments for patients. At Science Care, we provide the opportunity to make a final choice with control and dignity. Our donors know that their last act was donating to the welfare of humankind, and their gift provides a lasting legacy.
Proper citation: ScienceCare (RRID:SCR_004457) Copy
http://www.psychologytoday.com/blog/the-compass-pleasure
A blog written by David J. Linden, Ph.D., professor of Neuroscience at the Johns Hopkins University School of Medicine, focusing on the brain''s pleasure circuits. Topics covered include exercise, pleasure and the brain; and understanding the biology of runners high. The Compass of Pleasure: How Our Brains Make Fatty Foods, Orgasm, Exercise, Marijuana, Generosity, Vodka, Learning, and Gambling Feel So Good is also a book and available for purchase. David J. Linden, Ph.D., is a professor in the Department of Neuroscience at the Johns Hopkins University School of Medicine. His laboratory has worked for many years on the cellular substrates of memory storage in the brain and a few other topics. He has a longstanding interest in scientific communication and serves as the Chief Editor of the Journal of Neurophysiology. He has written two books for a general audience about the biological basis of mental function: The Compass of Pleasure (Viking Press, 2011) and The Accidental Mind (Harvard/Belknap, 2007).
Proper citation: Compass of Pleasure (RRID:SCR_004756) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. The Dana-Farber/Harvard Cancer Center Pathology Specimen Locator (PSL) is a core developed to facilitate translational research requiring human specimens. The PSL is a distributed network of databases containing de-identified pathology reports and other specimen information from IRB-approved repositories within Dana-Farber/Harvard Cancer Center affiliated institutions. Using the PSL, researchers can work with the pathology departments to find appropriate specimens for their research. The Harvard VLS currently contains approximately two million de-identified pathology reports from the four main Harvard Teaching Hospitals.
Proper citation: Dana Farber Tissue Bank (RRID:SCR_004352) Copy
BIO - OPTIONS provides human tissues and biological materials to researchers and scientists for molecular and genomic research. These high quality, well characterized biological specimens are available for drug and biomarker discovery, validation of drug targets and development of diagnostic tests and devices. BIO - OPTIONS specializes in providing fresh tumor tissue, blood and other biological fluids delivered the same day or overnight for your studies. We collect specimens from virtually all disease states through our extensive network of physicians, hospitals, and clinical laboratories. All of our specimens are collected at facilities located in the United States in compliance with all applicable federal and state laws and regulations and ethical guidelines. Collection facilities are located on the East and West coasts and Midwest. The officers of BIO - OPTIONS consist of licensed physicians with extensive medical training and experience. This enables us to work directly with physicians and support staff to insure that collection protocols provide the high quality specimens needed for research without compromising patient care. Protocols are designed to work within the workflow of physician offices and hospital operating rooms so that specimens are timely processed and preserved and well characterized.
Proper citation: Bio-Options (RRID:SCR_004594) Copy
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