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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.ohsu.edu/multiscale-microscopy-core
Multiscale Microscopy Core at OHSU is electron microscopy core that provides services and training to academic and corporate users.
Proper citation: Oregon Health and Science University Multiscale Microscopy Core Facility (RRID:SCR_009969) Copy
https://www.ohsu.edu/advanced-light-microscopy-core
Provides confocal image analysis and presentation training, microscope training, microscope access service, deconvolution training, super resolution imaging and training service. Offers research scientists access to high-end instrumentation for fluorescence microscopy. Offers support with image acquisition, processing, analysis and presentation.
Proper citation: OHSU Advanced Light Microscopy Core Facility (RRID:SCR_009961) Copy
https://www.ohsu.edu/xd/research/research-cores/advanced-computing-center/index.cfm
Provides technology solutions to meet non enterprise IT needs across OHSU for healthcare including limited clinical research project support, academic, and research missions. ACC is also home to Exacloud HPC cluster.
Proper citation: OHSU Advanced Computing Center Core Facility (RRID:SCR_009959) Copy
https://www.ohsu.edu/research-cores/massively-parallel-sequencing-shared-resource-mpssr
As of January 1, 2024, the Integrated Genomics Laboratory is one shared resource comprising the former Massively Parallel Sequencing Shared Resource, the Gene Profiling Shared Resource, and the DNA Services Core. Please be aware that the reorganization is an ongoing process, particularly regarding our iLab integration.Provides RNA-sequencing for gene expression analysis, DNA resequencing for single nucleotide polymorphism discovery, DNA resequencing for copy number variation discovery, ChiP-sequencing for promoter analysis, DNA methylation analysis, De novo sequencing for unique genomes, Sequence capture service. Offers sequencing including genome resequencing, transcriptome analysis, miRNA analysis, and prometer analysis via ChIP-seq.
Proper citation: OHSU Massively Parallel Sequencing Shared Resource Core Facility (RRID:SCR_009984) Copy
http://www.ohri.ca/stemcore/Default.aspx
StemCore Laboratories is a high-throughput genomics facility within the Ottawa Hospital Research Institute (OHRI). Core is capable of facilitating large-scale scientific research and biotechnology projects.Provides infrastructure for genomics, bioinformatics, and proteomics.
Proper citation: Ottawa Hospital Research Institute StemCore Laboratories Core Facility (RRID:SCR_012601) Copy
https://www.salk.edu/science/core-facilities/integrative-genomics-and-bioinformatics-core/
Core houses state-of-the-art equipment in sequencing and genomics, including high-throughput sequencing systems such as Illumina NovaSeq 6000, NextSeq 2000, MiniSeq, and PacBio Sequel IIe system (long-read sequencing), as well as 10x Genomics Chromium Controller single-cell solution, NanoString nCounter MAX Analyzer, and GeoMx Digital Spatial Profiler instrument, along with QuantStudio Real-Time PCR instruments.
Proper citation: Salk Institute Next Generation Sequencing Core (NGS) (RRID:SCR_014846) Copy
http://www.waksman.rutgers.edu/genomics/home
Equipped with NextSeq500, MiSeq, and Ion Proton performs de novo genome sequencing, genome resequencing, ChIP-Seq and RNA-seq. Performs library construction, template preparation and sequencing of libraries or provides training in library preparation methods.Performs procedures to enrich or remove polyadenylated RNA, rRNA and/or tRNA as needed. Provides bioinformatics support for projects,data management and analysis plan before selecting samples and initiating data collection.
Proper citation: Rutgers University Waksman Institute of Microbiology Genomics Core Facility (RRID:SCR_011042) Copy
https://www.urmc.rochester.edu/research/rochester-genomics-center.aspx
Provides core laboratory support, technical consultation, assistance with experimental design and data analysis for investigators using high throughput genomic sequencing, genotyping and gene expression in their research programs.Provides support for RNA-Seq, ATAC-seq, ChIP-Seq, Single Cell RNA-seq, Spatial Transcriptomics, Exome/Genome sequencing, Whole Genome and Reduced Representation Bisulfite Sequencing (WGBS, RRBS), 16S rRNA Sequencing, Small RNA-Seq, Metatranscriptomics, qRT-PCR, processing of RNA/DNA, as well as custom applications and approaches. Bioinformatic analysis support is also available.
Proper citation: University of Rochester Genomics Research Center Core Facility (RRID:SCR_012359) Copy
http://www.montana.edu/massspec/index.html
Provides access to mass spectrometers and mass spectrometry expertise. The facility currently maintains the following equipment Waters Synapt-XS Q-IMS-TOF with Waters I-Class UHPLC; Agilent 6538 Q-TOF with Agilent 1290 UHPLC;Agilent 7800 Inductively Coupled Plasma with Laser Ablation (193 nm);Bruker micrOTOF with Agilent 1290 UHPLC; Agilent 6490 Triple Quadrupole Mass Spectrometer; Bruker MALDI Autoflex; Agilent GC-MS; Waters Synapt G2S-i Q-TOF with Ion Mobility.
Proper citation: Montana State University Mass Spectrometry Core Facility (RRID:SCR_012482) Copy
https://www.urmc.rochester.edu/research/flow-core.aspx
Provides investigators with instrumentation along with expertise. Core instrumentation includes traditional analytical cytometers, full spectrum cytometer, cell sorters, imaging cytometers, small(nano) particle detection system, metabolomics instrument, and mass cytometer.
Proper citation: University of Rochester Medical Center Flow Cytometry Core Facility (RRID:SCR_012360) Copy
https://www.urmc.rochester.edu/research/electron-microscope.aspx
Electron Microscopy Resource supports ultra-structural interrogation of tissues, biologic solutions and nanomaterials for investigators utilizing transmission electron microscopy (TEM), scanning electron microscopy (SEM) and cryo-TEM.
Proper citation: University of Rochester Medical Center Electron Microscopy Core Facility (RRID:SCR_012366) Copy
Core provides molecular biotechnology services and current molecular genetic methods. Services include DNA and RNA Extraction, transgenic mouse genotyping, Human Cell line Authentication, Sanger DNA Sequencing, Next-Generation sequencing platforms, Microsatellite DNA Typing, Agena multiplex SNP Genotyping, Real-time PCR, NanoString Gene Expression Analysis. Specializes in custom workflows that couple services with specific research needs.
Proper citation: Arizona Genetics Core (RRID:SCR_012429) Copy
https://cancer.dartmouth.edu/scientists-researchers/clinical-pharmacology
Supports Dartmouth Cancer Center investigators in design, performance, data analysis, and interpretation of pharmacology objectives in preclinical, clinical and epidemiological studies.
Proper citation: Dartmouth College Clinical Pharmacology Shared Resource Core Facility (RRID:SCR_000873) Copy
https://www.colorado.edu/facility/ems/
Core provides access to instruments including:FEI Tecnai 12 Spirit TEM, FEI Tecnai F20 (200kV) FEG-TEM 200kV FEG-TEM,Gatan US4000 4k x 4k CCD, bottom-mount,CryoTEM and electron tomography,High-resolution TEM;FEI Tecnai F20 (200kV) FEG-TEM,300kV FEG-TEM,Gatan US4000 4k x 4k CCD, bottom-mount,CryoTEM and electron tomography,High-resolution TEM,FEI/Phillips CM100 (100kV) TEM,100kV, tungsten TEM,2k x 2k AMT CCD, bottom-mount.
Proper citation: Colorado University at Boulder EM Services Core Facility (RRID:SCR_001432) Copy
https://www.med.upenn.edu/idom/drc/cores/rodent.html
Core (RMPC, formerly MPPMC) is metabolic core. Offers technology and phenotyping services to allow investigators to study metabolism in pre-clinical rodent models. Services include measurements of body composition (fat and lean mass) using NMR and DEXA, energy balance (food intake, locomotor activity, energy expenditure) using indirect calorimetry in either Columbus Instruments CLAMS system or Sable Systems Promethion System (with optional gas analyzer), and other in vivo metabolic phenotyping services (glucose clamps, insulin and glucose tolerance tests, telemetric monitoring of blood glucose or blood pressure, bomb calorimetry).
Proper citation: University of Pennsylvania Perelman School of Medicine Rodent Metabolic Phenotyping Core Facility (RRID:SCR_022427) Copy
https://www.med.upenn.edu/ipsccore/
Provides resources for disseminating human pluripotent stem cell technology within UPenn and surrounding research communities. �Our services include derivation of patient specific iPSCs, genome engineering of stem cell lines using CRISPR/Cas9 technology, and lineage specific differentiation of iPSCs/hESCs in 2D and 3D organoid culture.�Core has large collection of patient derived iPSC lines and cell lines of gastrointestinal tract (esophageal, pancreatic and intestinal) available to users.�Committed to training investigators in stem cell culture techniques and providing quality tested stem cell reagents to users.
Proper citation: University of Pennsylvania Perelman School of Medicine Induced Pluripotent Stem Cell Core Facility (RRID:SCR_022426) Copy
https://www.biotech.cornell.edu/core-facilities-brc/facilities/genomics-innovation-hub
Core complements services provided by BRC Genomics Facility.Working on collaborative model, protocol and method development by early adopters pave the way for larger scale production services.
Proper citation: Cornell University BRC Genomics Innovation Hub Core Facility (RRID:SCR_022547) Copy
https://www.med.upenn.edu/ris/
Shared resource machine shop serving various University of Pennsylvania Schools and Departments. Assists researchers to design and construct both laboratory and clinical instruments.
Proper citation: University of Pennsylvania Perelman School of Medicine Research Instrumentation Shop Core Facility (RRID:SCR_022424) Copy
https://www.dental.upenn.edu/research/core-facilities/
Provides Becton Dickinson LSR II flow cytometer equipped with four lasers.Blue laser can be used to detect forward and side scatter and 4 colors (eg., FITC/Alexa 488, PE, PerCP-CY55, PE-CY7), red laser can be used to detect 2 colors (e.g., APC and APC-CY7), violet laser can be used to detect 2 colors (e.g., Pacific blue, Am cyan) and a UV laser which can also be used to detect 2 colors (e.g., INDO1 blue, Indo1-violet/DAPI). The instrument is located in Room 330 in the Levy Building (240 South 40th Street).
Proper citation: University of Pennsylvania Penn Dental Medicine Flow Cytometry Core Facility (RRID:SCR_022443) Copy
https://www.vet.upenn.edu/research/core-resources-facilities/referral-center-for-animal-models
Core mission is to discover, create, characterize, treat, and share naturally occurring hereditary disorders in dogs and cats that are orthologous to those found in human patients.�Provides expertise in discovering, characterizing, and developing therapies for genetic disease in dogs and cats, which serve as models of same diseases that occur in children.�Specializes in molecular discovery of mutations, clinical phenotyping, biochemical and histological characterization, development of therapies which are translatable to human patients and preclinical trials in animal models of human disease.�
Proper citation: University of Pennsylvania Penn Vet Referral Center for Animal Models of Human Genetic Disease Core Facility (RRID:SCR_022440) Copy
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