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PathServe Autopsy And Human Tissue Bank is a tissue supplier for bioresearch and educational institutions. It was established in 1990 in order to better satisfy the needs of Bay Area hospitals using inexpensive and reliable postmortem examinations. Today we''ve grown into a multidepartmental organization; serving nationwide as a human tissue supplier to biotech and neuropathological research institutions as well as a centralized autopsy provider to private citizens and local hospitals.
Proper citation: PathServe (RRID:SCR_010695) Copy
THIS RESOURCE IS NO LONGER IN SERVICE, documented on October 6, 2011. A project to collect, store and study DNA samples from tens of thousands of healthy volunteers and patients with diseases of major public importance. It aims to identify genes that are risk factors for the conditions. The network consists of 13 collections led by different clinicians throughout the UK. At its heart is an archive infrastructure which manages the DNA and the information associated with it. The European Collection of Cell Cultures in Porton Down handles the blood, peripheral blood lymphocytes and EBV-transformed cell lines, while the Centre for Integrated Genomic Medical Research at Manchester University manages the DNA. These banked samples are available to UK and international researchers, who can examine data and set up collaborative work by registering at the DNA Network's website. The conditions for which samples are currently collected and stored are: Acute leukemia, Asthma and eczema, Late onset Alzheimer's disease, Breast cancer, Colorectal cancer, Coronary artery disease, Glomerulonephritis, Hypertension, Age-related macular degeneration, Multiple sclerosis, Parkinson's disease, Type 2 diabetes, Unipolar depression.
Proper citation: UK DNA Banking Network (RRID:SCR_010619) Copy
As both the public health survey of Quebec, and the Quebec resource for scientists interested in personalized medicine, genomics and public health, this public resource operates under a governance framework and consists of a databank and a biobank. The database contains environmental, demographic and health data. The biobank contains DNA, blood and urine samples. Access to CARTaGENE will be granted to researchers who are seeking to better understand how genes interact with other genes, with the environment and with lifestyle factors. They have collected in-depth information on over 20 000 Quebecers, including 446 sociodemographic, life-style and health data, 190 physiological parameters, 22 types of biochemical analyses and 41 types of haematological analyses. They have also collected 11 types of blood, plasma, serum and urine samples from most participants. Genealogical reconstruction of recruited participants, in collaboration with BALSAC Project, is also possible. CARTaGENE data and samples include the following: Health Questionnaire, Physical measures, Biochemical and hematological analysis, Biological samples stored in the Biobank. CARTagene is currently contacting participants (who have agreed to be recontacted) to collect additional data on environmental exposure. Data on dietary habits will be collected during the second phase of this component which will begin soon. Any scientific researcher working in a public or private organization at the national or international level may apply for access to CARTaGENE samples or data.
Proper citation: CARTaGENE (RRID:SCR_010614) Copy
http://www.istge.it/crb/english.htm
The Centro di Risorse Biologiche (CRB-IST), institutional facility of IST, has been recently established by the General Director (Deliberation number 624 July 11, 2008). It aims at co-ordinating already existing biobanking activities, and participating in the European Infrastructure of Biobanks and Biomolecular Resources (BBMRI), in preparation in the frame of the 7th FP of the European Community. Aims: * to facilitate high quality translational research dependent on biological material and data * to address ethical issues on biobanking * to promote the project at the population level * to co-ordinate the IST biobanks and cell banks * to harmonize technical and management SOPs, according to international best practices * to help reduce costs for collection and storage of biological material * to favor institutional recognition at a regional, national and international level - to sustain the role of the Institute in the European infrastructure.
Proper citation: Biological Resource Centre - National Institute for Cancer Research (RRID:SCR_010548) Copy
Stroke patient registry containing thousands of patient CT scans, primarily as well as follow up medical information.
Proper citation: Stroke Registry in Chang Gung Healthcare System (RRID:SCR_011083) Copy
http://www.nitrc.org/projects/gig-ica/
Software toolbox for group-information guided Independent Component Analysis (ICA). In GIG-ICA, group information captured by standard Independent Component Analysis (ICA) on the group level is used as guidance to compute individual subject specific Independent Components (ICs) using a multi-objective optimization strategy. For computing subject specific ICs, GIG-ICA is applicable to subjects that are involved or not involved in the computation of the group information. Besides the group ICs, group information captured from other imaging modalities and meta analysis could be used as the guidance in GIG-ICA too.
Proper citation: Group Information Guided ICA (RRID:SCR_009491) Copy
Service that retrieves disease relevant information from Twitter tweets and shows current hotspots of disease outbreaks on an interactive map. It is an ontology-driven system for detecting global health events
Proper citation: BioCaster (RRID:SCR_011869) Copy
http://www.chernobyltissuebank.com/
The CTB (Chernobyl Tissue Bank) is an international cooperation that collects, stores and disseminates biological samples from tumors and normal tissues from patients for whom the aetiology of their disease is known - exposure to radioiodine in childhood following the accident at the Chernobyl power plant. The main objective of this project is to provide a research resource for both ongoing and future studies of the health consequences of the Chernobyl accident. It seeks to maximize the amount of information obtained from small pieces of tumor by providing multiple aliquots of RNA and DNA extracted from well documented pathological specimens to a number of researchers world-wide and to conserve this valuable material for future generations of scientists. It exists to promote collaborative, rather than competitive, research on a limited biological resource. Tissue is collected to an approved standard operating procedure (SOP) and is snap frozen; the presence or absence of tumor is verified by frozen section. A representative paraffin block is also obtained for each case. Where appropriate, we also collect fresh and paraffin-embedded tissue from loco-regional metastases. Currently we do not issue tissue but provide extracted nucleic acid, paraffin sections and sections from tissue microarrays from this material. The project is coordinated from Imperial College, London and works with Institutes in the Russian Federation (the Medical Radiological Research Centre in Obninsk) and Ukraine (the Institute of Endocrinology and Metabolism in Kiev) to support local scientists and clinicians to manage and run a tissue bank for those patients who have developed thyroid tumors following exposure to radiation from the Chernobyl accident. Belarus was also initially included in the project, but is currently suspended for political reasons.
Proper citation: Chernobyl Tissue Bank (RRID:SCR_010662) Copy
An open-source toolkit for cross-sectional and longitudinal atlas building. The CalaTK project develops innovative methods and tools for longitudinal atlases with a focus on neurodevelopment. The computational toolbox is developed with the objective to analyze the neural developmental patterns observed in human and non-human primate structural and diffusion tensor magnetic resonance (MR) images.
Proper citation: CalaTK (RRID:SCR_009547) Copy
A biomaterial supply resource which provides high quality, clinically and neuropathologically well-characterised human brain and spinal cord tissue. The Brain Bank focuses on neurodegenerative diseases such as Alzheimer’s Disease (AD), Frontotemperal dementias (FTD) and Motor Neurone Disease (MND). However, it also contains tissues for the study of HIV, Autism and Schizophrenia, and movement disorders.
Proper citation: MRC London Neurodegenerative Diseases Brain Bank (RRID:SCR_013839) Copy
http://www.oucom.ohiou.edu/Biorepository/biorepository_inventory.htm
Plasma and cell fractions obtained from patients with Diabetes and endocrine diseases and their first degree relatives who agreed to participate in the development of the biorepository. Plasma is aliquoted into multiple specimen containers and stored at -80C. Cell fractions are subjected to DNA and RNA fractionation, aliquoted into multiple specimen containers, and frozen at -70 to -80 degrees centigrade. Anyone who would like to obtain samples from the Biorepository must provide evidence that they have adequate training in the use of bloodborne pathogens, as outlined by OSHA. The investigator must agree to indemnify and hold harmless the Ohio University Diabetes/Endocrine Diseases Biorepository, the Appalachian Rural health Institute, and the Ohio University College of Osteopathic Medicine from any claims, liability, costs, and damages.
Proper citation: Ohio U Diabetes Endocrine Biorepository (RRID:SCR_013435) Copy
A biomaterial resource which stores and distributes dissected human brain samples and topographically oriented tissue blocks. Most brains were removed from the skull and frozen within 2-6 hours after death. The microdissection of 260 different brain nuclei is performed on frozen brains and the samples are kept in -70ºC. Materials must be studied in the course of an approved research project, which has scientific aims and is devoid of any commercial profit for the researches involved and for their respective institutions.
Proper citation: Human Brain Tissue Bank (RRID:SCR_013837) Copy
A biomaterial supply resource which collects, stores, and disseminates biomaterial and clinical data relating to neurological disorders, psychiatric disorders, cardiology pathologies, and pneumology pathologies. NeuroBioTec has 18 collections with a total of 100,000 samples of serum, plasma, cerebrospinal fluid, PBMC, urine, tissue, DNA and RNA. Some samples can be made available to external researchers under certain conditions.
Proper citation: NeuroBioTec (RRID:SCR_013842) Copy
SAPALDIA (Swiss study on Air Pollution and Lung Disease in adults) is a multi-center study in eight geographic areas representing the range of environmental, meteorological and socio-demographic conditions of Switzerland, which studies the effects of air pollution on the respiratory and cardiovascular health in adults. Local centers are: Aarau, Basel, Davos, Geneva, Lugano, Montana, Payerne, and Wald. It was initiated in 1991 (SAPALDIA 1) with a follow-up assessment in 2002 (SAPALDIA 2). This study has allowed to assess 1) prevalence and development of major respiratory and allergic symptoms and diseases and the age-related decline in lung function, 2) the distribution of heart rate variability in the general population over age 50, 3) the association of these health indicators with individual long term exposure to air pollution, other toxic inhalants, life style and molecular factors. Another follow-up examination (SAPALDIA 3) started in January 2010. This study is well positioned to address crucial questions of air pollution epidemiology and important environmental health policy-related questions in the coming years. When SAPALDIA was initiated in 1991, 9''''651 subjects, aged 18 to 60 years, were recruited for a detailed computer-based interview and more than 90% of them underwent lung function and atopy testing. More than 7''''000 of the subjects had bronchial reactivity tested by a methacholine challenge. SAPALDIA shares parts of its study protocol with the European Community Respiratory Health Survey (ECRHS) with which it is linked through the study center of Basel. Since 1991 SAPALDIA has been carefully following address histories of its participants. In the 2002 follow-up, 8''''047 (83%) provided health information, 6''''528 persons underwent physical re-examination, and 6''''345 provided blood samples to establish an extensive blood, plasma, serum and DNA bank. In addition, 1''''813 subjects aged 50 or older participated in 24h-ECG Holter monitoring to provide detailed data on parameters of heart rate variability. With the inclusion of cardiovascular endpoints, SAPALDIA is one of the first studies examining effects from long-term exposure to air pollution on cardiovascular health parameters as well as mutual influence between the respiratory and the cardiovascular system. The SAPALDIA bio-bank has allowed scientific publications on the association between some genetic profiles (gene polymorphism) and the propensity to develop asthma, allergic diseases, or accelerated lung function decline with age. Ongoing studies are focusing on gene-environment interactions a crucial question to understand why some persons suffer more from the effect of air pollution than others.
Proper citation: SAPALDIA (RRID:SCR_013416) Copy
http://www.stritch.luc.edu/depts/path/residency/anatomic_pathology.htm#Neuropathology
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 31, 2016. A medical center with a neuropathology research program focused on the normal and abnormal aging process of the central nervous system and a funding source for research. The center serves as a collection site for brains in order to study normal aging and neurodegenerative diseases like Alzheimer's.
Proper citation: Loyola University Medical Center / Hines VA Brain Bank (RRID:SCR_013277) Copy
http://www.uzh.ch/keyinst/loreta
Software application which computes cortical three-dimensional distribution of current density of the brain based on the scalp-recorded electric potential distribution. The exact low resolution brain electromagnetic tomography method has the property of exact localization to test point sources, yielding images of current density with exact localization, albeit with low spatial resolution. eLORETA has no localization bias even in the presence of structured noise. Deep structures, such as the anterior cingulate cortex and mesial temporal lobes, can be correctly localized with these methods.
Proper citation: exact Low Resolution Electromagnetic Tomography (RRID:SCR_013830) Copy
Nationwide organ and tissue donor registry that is a private, non-profit organization dedicated to the enhancement of organ and tissue donation. They educate the community about the urgent need for donors so no one dies or suffers for lack of donation, honor donors and support organ recipients, living donors and their families. They are cognizant of the many challenges ahead before the day comes when no one will die because a donor organ was not available at the time of need. The Board and Staff of The Living Bank dedicate their efforts to increase the number of registered-informed donors. The programs and services of The Living Bank are: # The Living Donor Bank Program advocates and supports living donors before, during and after the donation process. # Travel Stipend/Donor Support Program assists living donors in arranging transportation and provides stipends if they must travel to donate. # Donor Education Program educates the public regarding the donation and use of organs and tissues and provide donor cards.
Proper citation: Living Bank (RRID:SCR_005018) Copy
http://ki.se/en/imm/the-imse-studies-imse-i-and-imse-ii
Immunomodulatory drugs in multiple sclerosis (IMSE) is a nation-wide pharmacoepidemiological and genetic study on persons treated with Tysabri. The study focuses on response to treatment and development of neutralizing antibodies, and to perform large-scale genetic studies. Sample types * EDTA whole blood * DNA * Plasma Number of sample donors: 1293 (June 2010)
Proper citation: KI Biobank - IMSE (RRID:SCR_005899) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29354&a=31616&l=en
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. The study Genetic Regulation of the End-Stage Clotting Process that leads to Thrombotic Stroke (EuroClot) aims specifically to identify the major genes involved in variations of the end-stage clotting process and investigate the role of these novel genes (and existing candidate genes) in the pathogenesis of stroke across Europe. EuroClot will study stroke intermediate phenotypes in 4500 twins from GenomEUtwin project involving 8 countries and 1000 subjects from extended families from the GAIT2 (Spain) and EuroHead (Finland) studies. Types of samples * EDTA whole blood * DNA * Plasma * Serum Number of sample donors: 601 (sample collection completed)
Proper citation: KI Biobank - EuroClot (RRID:SCR_005932) Copy
Repository of person centered measures that evaluates and monitors physical, mental, and social health in adults and children.
Proper citation: Patient-Reported Outcomes Measurement Information System (RRID:SCR_004718) Copy
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