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http://biobanknetwork.telethon.it/
Network of non profit association of Italian repositories to form catalogue of biospecimens and associated data. Used to collect, process, preserve and distribute biological samples and related clinical data from individuals affected by rare diseases, their relatives or from healthy control individuals, with standards complying with Italian laws and international recommendations. You may browse sample catalogue by diagnosis or use advanced search option. Request for samples is granted only if project is in agreement with TNGB mission and after receiving signed material transfer agreement form.
Proper citation: Telethon Network of Genetic Biobanks (RRID:SCR_004658) Copy
The foundation biobank-suisse (BBS) is a collaborative network of existing and future research biobanks in Switzerland. The primary goals are: 1. to provide researchers a quick overview of available human biospecimens (by using the web query interface) and up to date person related data; and 2. to provide biobankers with services to further improve the quality of biobanks in Switzerland (e.g. information about up-to-date IT and database software for biobanking; solutions for ethical, legal, and social issues; develop common platform for biobankers; etc.). We maintain a database with data about patients and biospecimens. The database can be queried from our web-site. Once the researcher has found suitable biospecimens we will bring him in contact with the biobanks, which have collected the biospecimen. The researcher and the biobank manager will then discuss the next step without further participation of the foundation biobank-suisse. We provide advice and support to biobank manager, who are in the process to start a biobanking activity for material from humans. Well established biobanks can benefit from our help in realizing specific projects to improve their operations. BBS was founded in December 2005 as an initiative of Oncosuisse and SWISS BRIDGE with the goal to build a collaborative network of existing and future biobanks for research in Switzerland. BBS has currently information from about 60 000 biospecimens and 10 000 patients. This information is provided by the biobanks shown under the Partner biobank menu item and include: * Institut de Pathologie, Centre hospitalier universitaire vaudois (CHUV) * Institut f��r Pathologie Universit��tsspital Basel * Institut f��r Pathologie der Universit��t Bern BBS has entered in a closed collaboration with SAKK''s (Swiss Working Group on Clinical Cancer Research) IT department. BBS''s server is run by SAKK and technical support is provided by the SAKK IT department. BBS is an active member of ISBER (International Society of Biological and Environmental Repositories) the international society of biobanks. BBS also joint BBMRI (an European initiative to build an pan-European network of biobanks.
Proper citation: Biobank Suisse (RRID:SCR_004935) Copy
http://www.tissuebank.dundee.ac.uk/
Tayside Tissue Bank is a secure bio-repository which holds small samples of surplus tissue and other specimens generously donated by patients who have undergone surgery or other more minor medical procedures during the course of their investigations and treatment. Such samples are vital for medical researchers seeking to improve the detection and treatment of many different diseases as well as advance our understanding of how and why they arise. This website is for both patients who wish to know more about how their tissue is used and for researchers who wish to explore the possibility of utilising the donations kindly made by patients to advance medical research. It also explains some of the additional services the Tissue Bank provides to assist researchers with their investigations including: embedding and cutting sections, standard histological staining, immunohistochemistry (IHC), nucleic acid extraction, protein extraction, and generation of Tissue Microarrays. Donations made to the Bank are held within ultra-low temperature (ULT) freezers within the University of Dundee Medical School at Ninewells Hospital, Dundee. The freezers are alarmed and their temperature continuously monitored. The Bank''s location adjacent to the Pathology Department means it is ideally situated for prompt processing and storage of tissue samples after they have been examined by a pathologist. In addition to collecting, logging and storing tissue samples the bank also holds blood specimens and other materials collected as part of national trials. It also plays a role in administering access to the Tayside Type II diabetes cohort. The Bank contains in the region of 30,000 fresh frozen tissue samples from around 6000 different patients. There are also in excess of 5000 blood samples. Storage of the samples is split between separate, continuously monitored freezers. In addition the Bank has access to the Pathology Department''s Histopathology Archive (30,000 new specimens annually).
Proper citation: Tayside Tissue Bank (RRID:SCR_004927) Copy
Collects, processes, and distributes human blood products to hospitals and research-related organizations. They operate donor centers and mobile donor vehicles to collect transfusable blood products from healthy donors, and offer human-derived blood products to research organizations. HemaCare also provides blood related services, principally therapeutic apheresis procedures, stem cell collection and other blood treatments, to patients and in connection with clinical trials.
Proper citation: HemaCare Corp. (RRID:SCR_004803) Copy
Collects and stores genetic (DNA) samples along with associated healthcare information from patients of Northwestern-affiliated hospitals and clinics. This resource is available to scientists to conduct groundbreaking genetic research. The information and blood samples provided will be used by researchers to examine the role genes play in the development and treatment of common diseases. The NUgene Project seeks to increase the understanding of genetic mechanisms underlying common diseases, assist in the development of DNA-based technology for diagnosis and treatment of disease, and aid physicians and other healthcare providers in the application of genetics to the practice of medicine. NUgene participants are recruited throughout the Northwestern-affiliated healthcare community in order to create an ethnically and medically diverse population for research. Participants must be 18 years of age or older and receive their medical care from a Northwestern-affiliated provider, regardless of health status. Consenting individuals complete all aspects of enrollment in a single meeting with a research coordinator. The enrollment process includes the donation of a single sample of blood and the completion of a self-administered questionnaire. Participants also sign a consent form during this encounter. The NUgene Project is an interdisciplinary project that relies on the expertise of individuals working in a variety of fields, including science, medicine, clinical research, statistics, epidemiology, and computational biology. NUgene''s multidisciplinary approach has spurred collaborations within Northwestern-affiliated institutions and with other outside institutions. This collaboration of ideas is the future of genetics and genomic research., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: NUgene Project (RRID:SCR_007426) Copy
https://nntc.org/content/relationship-charter
THIS RESOURCE IS NO LONGER IN SERVICE, documented April 14, 2017. Clinical trial designed to determine how central and peripheral nervous system complications of HIV are affected by different histories and regimens of antiretroviral therapy (ART). CHARTER is able to provide fluid specimens, pilot data, and analysis and interpretation expertise for qualified investigators.
Proper citation: CHARTER - CNS HIV Antiretroviral Therapy Effects Research (RRID:SCR_008070) Copy
Project to improve data and sample exchanges and to facilitate large scale analysis of data by improving interoperability of French Biological Resources Centres (BRC or biobanks) IT systems and biological databases. The work done in this project will be linked to other national (IBiSA, ANR, R��seau des Biobanques, Club 3C-R), European (BBMRI, ELIXIR) or international project (P3G). In the preliminary phase (2009-2010) I3-CRB has developed a directory of French Biological Resource Centres / Biobanks where one may register their French BRC or perform a search across all of them. Detail by overall data or kingdom is provided as well as many filtering options. Access to biological samples is provided by the participating BRC''''s. Biological Resources Centres (BRC or biobanks) collect annotated biological samples from various sources (human, animal, plant, bacteria...). The type of samples depends on the collection and the associated thematic (DNA, proteins, cells, tissues, blood, serum, organisms...). The aims of these centers are to collect, to store, to transform and to distribute the biological samples. They constitute a vital infrastructure for life science and health research. Goals of the French Biobanks/Biological Resource Centres: * List French biobanks and their biological collections * Improve sample exchanges * Improve the international visibility of the French biological collections MeSH terms have been integrated: Domains, diseases, and location of the disease (Anatomy). Collections/species are based on NCBI Taxonomy.
Proper citation: I3-CRB: Interoperable IT Infrastructure for Biological Resources Centres / Biobanks - France (RRID:SCR_006991) Copy
http://www.uzh.ch/keyinst/loreta
Software package for functional imaging of human brain. Used to compute three dimensional distribution of electric neuronal activity from non-invasive measurements of scalp electric potential differences with high time resolution in millisecond range. Non-invasive intracranial time series are used for studying functional dynamic connectivity.. Current software version includes two new, improved variants of the original method: standardized (sLORETA) and exact (eLORETA). The new methods are characterized by exact localization when tested with point sources. Due to the fact that these methods are multivariate tomographies that are solutions to the inverse EEG problem, and that they are linear in nature, they will produce a low spatial resolution image for any distribution of activity. This property is not shared by naive one-at-a-time single dipole techniques.
Proper citation: Low Resolution Electromagnetic Tomography (RRID:SCR_007077) Copy
http://www.niaid.nih.gov/about/organization/dait/pages/csgadp.aspx
Collaborative network of investigators with a focus on prevention of autoimmune disease, defined as halting the development of autoimmune disease prior to clinical onset by means other than global immunosuppression, and an emphasis on Type 1 diabetes. Its mission is to engage in scientific discovery that significantly advances knowledge for the prevention and regulation of autoimmune disease. The specific goals enunciated in pursuit of this mission are: * To create improved models of disease pathogenesis and therapy to better understand immune mechanisms that will provide opportunities for prevention strategies * To use these models as validation platforms with which to test new tools applicable to human studies * To encourage core expertise and collaborative projects designed for rapid translation from animal to human studies, emphasizing the development of surrogate markers for disease progression and/or regulation which can be utilized in the context of clinical trials
Proper citation: Cooperative Study Group for Autoimmune Disease Prevention (RRID:SCR_006803) Copy
Collection of human embryonic and fetal material (Tissue and RNA) ranging from 3 to 20 weeks of development available to the international scientific community. Material can either be sent to registered users or our In House Gene Expression Service (IHGES) can carry out projects on user''''s behalf, providing high quality images and interpretation of gene expression patterns. Gene expression data emerging from HDBR material is added to our gene expression database which is accessible via our HUDSEN (Human Developmental Studies Network) website. A significant proportion of the material has been cytogenetically karyotyped, and normal karyotyped material is provided for research.
Proper citation: Human Developmental Biology Resource (RRID:SCR_006326) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29346&a=31622&l=en
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 3rd,2023. Secondary prevention of ischemic heart disease in primary care, a randomized controlled intervention study. The study aims to elucidate if an early, active, group-oriented intervention at the primary care level can decrease the probability of developing a new cardiovascular event within three years, when compared to primary care according to standard protocols. The study also aims at analyzing how the intervention affects parameters as physical activity, eating habits, quality of life, blood pressure, waist measure, and smoking habits. Furthermore, changes in biochemical markers related to glucose- and lipid metabolism, stress related hormone production and sub clinic inflammatory activity as well as the presence of DNA polymorphism in the IL-6- and adiponutrin (ADPN) genes, will be investigated. Types of samples * EDTA whole blood * DNA Number of sample donors: 102 (sample collection completed)
Proper citation: KI Biobank - Sodertaljehjartan (RRID:SCR_006047) Copy
http://www.brainresource.com/personalized-medicine/webneuro
An on-line assessment tool for cognitive strengths and weaknesses compared to the normal standards as found in the Brain Resource database. Available to clinicians and employers. The assessment takes approximately 30 minutes and the completed report is then provided within minutes to the individual''s clinician, providing detailed analysis of cognitive strengths and weaknesses., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: WebNeuro (RRID:SCR_006049) Copy
Database and biorepository from a multi-site, multi-disciplinary study characterizing the familial transmission of alcoholism and related phenotypes and identifying susceptibility genes using genetic linkage. Investigators have assembled a collection of over 300 extended families densely affected by alcoholism (more than 3000 individuals), including clinical, neuropsychological, electrophysiological, biochemical, and genetic data, and established a repository of immortalized cell lines from these individuals, to serve as a permanent source of DNA for genetic studies. NIAAA has funded the Collaborative Studies on Genetics of Alcoholism (COGA) since 1989, with the goal of identifying the specific genes underlying this vulnerability. Data and biomaterials are available to qualified investigators in the broader scientific community. Recipients of data and biomaterials will be responsible for defraying the cost of their distribution. Pedigrees densely affected with alcoholism (DSM-III-R) have been ascertained at six sites (SUNY Downstate Health Sciences Center, University of Connecticut, Indiana University, Washington University, University of Iowa, and The University of California at San Diego). Diagnoses of alcohol dependence according to several diagnostic systems (e.g., DSM-III-R, Feighner, ICD-10) are made based on examination of medical records and direct assessment using the Semi-Structured Assessment for Genetics of Alcoholism (SSAGA). Nuclear and extended pedigrees containing at least two alcohol-dependent first-degree relatives in addition to an alcohol dependent proband (with all affected individuals meeting both DSM-IIIR and Feighner criteria) have been ascertained. Clinical data comprises anonymous data on family structure, age, sex, vital status, psychopathology, diagnosis, other clinically relevant information, are stored, maintained, and distributed by Washington University. Research data, consist of data on blood biochemistry and psychological test performance, which are stored, maintained, and distributed by Washington University, and brain electrophysiological data, which are stored, maintained, and distributed by SUNY. Genetic analysis data, consisting of marker genotypes, along with results of previous genetic analyses of COGA data, are stored, maintained, and distributed by Washington University. Biomaterials, consisting of lymphoblastoid cell lines and DNA from participating subjects are stored, maintained, and distributed by Rutgers University. Researchers may gain access to clinical data, research data, genetic analysis data, and biomaterials, subject to NIAAA approval, by completing an application details available from the website. After access certification, the principal investigator will be given access to electronic data files and other documentation.
Proper citation: Collaborative Studies on Genetics of Alcoholism (RRID:SCR_006841) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29346&a=80149&l=en
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016. CEFAM: Risk factors for atherosclerosis and cardiovascular disease, a randomized controlled study among women from the Middle East and Latin America. The study aims to analyze how two different physical activity programs in overweight and sedentary immigrant women influence changes in biomarkers related to glucose- and lipid metabolism, stress related hormone production, sub clinical inflammation, chronic cyclooxygenase mediated inflammation and oxidative stress.
Proper citation: KI Biobank - CEFAM (RRID:SCR_006044) Copy
An observational longitudinal clinical study partnership to identify and validate biomarkers of Parkinson disease (PD) progression and provide easy and open web-based access to the comprehensive set of correlated clinical data and biospecimens, information, and biosamples acquired from PD and age and gender matched healthy control subjects to the research community. The data and specimens have been collected in a standardized manner under strict protocols and includes clinical (demographic, motor and non-motor, cognitive and neurobehavioral), imaging (raw and processed MRI, SPECT and DAT), and blood chemistry and hematology subject assessments and biospecimen inventories (serum, plasma, whole blood, CSF, DNA, RNA and urine). All data are de-identified to protect patient privacy. PPMI will be carried out over five years at 21 clinical sites in the United States and Europe and requires the participation of 400 Parkinson's patients and 200 control participants. The PPMI database provides researchers with access to correlated clinical and imaging data, along with annotated biospecimens, all available within an open access system that encourages data sharing (http://www.ppmi-info.org/access-data-specimens/). The website hosts an Ongoing Analysis section to keep the scientific community apprised of analyses being completed, in hopes of stimulating collaborations between researchers who are using PPMI data and specimens.
Proper citation: Parkinson's Progression Markers Initiative (RRID:SCR_006431) Copy
http://ki-su-arc.se/dementia-in-swedish-twins-harmony/
A twin study characterizing the importance of genetic factors for dementia and using discordant twin pairs to study other putative risk factors which control for genetic propensity to develop the disease. Molecular genetic studies have identified a number of mutations and other markers associated with early age of onset Alzheimer''''s disease. However, most cases of late age of onset dementia are considered sporadic, that is, without a clear genetic basis. Twin studies provide a unique opportunity to characterize the importance of genetic factors for dementia. Discordant twin pairs additionally provide the opportunity to study other putative risk factors which controlling for genetic propensity to develop the disease. In the first wave of the Study of Dementia in Swedish Twins, all SATSA twins born before 1935 have been screened for dementia symptoms. Over 190 suspects have been identified. This pilot study has been expanded to the entire registry in the study known as HARMONY. All twins aged 65 and older were invited to participate in a computer assisted telephone screening interview. A total of 13,519 individuals completed the interview (response rate = 75.9%). Dementia screening was based on the TELE, which includes the 10-item MSQ, other cognitive items (counting backwards, recalling three words, and similarities), and questions about health and daily functioning; or on Blessed scores obtained from a proxy interview. Among those screened, 1565 were positive for suspicion of dementia and were referred for complete clinical evaluation by a physician and a nurse. Once the preliminary in-person evaluation suggested that the suspected case was demented, the twin partner was also invited for an identical clinical work-up. Response rate for clinical evaluations is 71.4%. Approximately half of those visited for evaluation have been diagnosed as demented according to DSM-IV criteria, of which two-thirds have Alzheimer''''s disease. An extensive assessment of probable risk exposure is also included. Longitudinal follow-up is yet another feature of the study. Association studies with candidate genes are also being performed. Types of samples * DNA Number of sample donors * 1154 (sample collection completed)
Proper citation: KI Biobank - HARMONY (RRID:SCR_008884) Copy
http://ki.se/en/research/the-swedish-twin-registry-1
The Swedish Registry was established in the 1960s to study how smoking affects our health. Then little was known about the dangers of smoking. There is, at present, information on approximately 85 000 twin pairs, both monozygotic and dizygotic. As described by Lichtenstein et al., 2002, Pedersen et al., 2002 and Lichtenstein et al., 2006, the Swedish Twin Registry (STR) is the largest and most comprehensive twin registry in the world. Founded in 1961, the registry covers all like-sexed twin births since 1886, and all twin births (like- and unlike-sexed) since 1906. There are currently 89,000 pairs of twins registered, of which both members of 65,000 pairs are alive, with regular updates concerning vital status, addresses, hospital discharges, tumors, and causes of death, through subscriptions to national registries. Furthermore, there is extensive epidemiological data (exposures, symptoms and disease through questionnaires or interviews) on all pairs born 1986 or earlier, for most individuals involving 30 year baseline to follow-up information. Furthermore, data from the cohort of twins born since 1991 have been or will be contacted with a telephone interview with the parents of twins as they turn 9 (CATSS). Because the STR is an (inter)national resource, we are receptive to collaboration academic and industry-based researchers. Regardless of the type of research all potential collaborations or data access agreements must be first reviewed Steering Committee of the STR.
Proper citation: Swedish Twin Registry (RRID:SCR_008883) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29350&a=31589&l=en
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. The aim of EXT (extinction) is to investigate the relation between specific genetic variations and cognitive control process in fear. Blood samples will be collected from about 300 healthy, young individuals (age 18-35).
Proper citation: KI Biobank - EXT (RRID:SCR_008875) Copy
http://ki.se/en/imm/sheep-the-stockholm-heart-epidemiology-program
DNA from a population-based case-control study designed to investigate causes of myocardial infarction. The study population comprised all Swedish citizens living in the county of Stockholm who were 45 to 70 years of age and free of previously clinically diagnosed MI. Sample types: * DNA Number of sample donors: 2831 (sample collection completed)
Proper citation: SHEEP - Stockholm Heart Epidemiology Program (RRID:SCR_008905) Copy
http://www.nltcs.aas.duke.edu/index.htm
A data set of a longitudinal survey designed to study changes in the health and functional status of older Americans (aged 65+). It also tracks health expenditures, Medicare service use, and the availability of personal, family, and community resources for caregiving. The survey began in 1982, and follow-up surveys were conducted in 1984, 1989, 1994, 1999, and 2004. The surveys are of the entire Medicare-enrolled aged population with a particular emphasis on the functionally impaired. As sample persons are followed through the Medicare record system, virtually 100% of cases can be longitudinally tracked so that declines, as well as increases, in disability may be identified as well as exact dates of death. NLTCS sample persons are followed until death and are permanently and continuously linked to the Medicare record system from which they are drawn. Linkage to the Medicare Part A and B service use records extends from 1982 to 2004, so that detailed Medicare expenditures and types of service use may be studied. Through the careful application of methods to reduce non-sampling error, the surveys provide nationally representative data on: * The prevalence and patterns of functional limitations, both physical and cognitive; * Longitudinal and cohort patterns of change in functional limitation and mortality over 22 years; * Medical conditions and recent medical problems; * Health care services used; * The kind and amount of formal and informal services received by impaired individuals and how it is paid for; * Demographic and economic characteristics like age, race, sex, marital status, education, and income and assets; * Out-of-pocket expenditures for health care services and other sources of payment; * Housing and neighborhood characteristics. In each of the six surveys, large samples (N~20,000) of the oldest-old population (i.e., those 85 and over) are obtained. The survey data (i.e., detailed community and institutional interviews. The linkage to Medicare enrollment files between 1982 and 2004 was 100%, i.e., there was complete follow-up of all cases (including survey non-respondents) for Medicare eligibility (and for most years, detailed Part A and B use), mortality, and date of death. Medicare mortality records (and dates of death) are available for 1982 to 2005. The number of deaths (i.e., about 32,000 from 1982 to 2005) is large enough that detailed mortality analyses can be done. Over the 22 years spanned by the six surveys, a total of 49,242 distinct individuals were followed from and linked to Medicare records. Data Availability: The data are available through ICPSR as Study No. 9681. The data are available only on CD-ROM and only upon completion of a signed Data Use Agreement. Continuously linked Medicare data (1982 through 2004) for the National Long Term Care Surveys are only available from CMS. * Dates of Study: 1982-2004 * Study Features: Longitudinal, Anthropometric Measures * Sample Size: ** 1982: 20,485 ** 1984: 25,401 ** 1989: 17,565 ** 1994: 19,171 ** 1999: 19,907 ** 2004: 20,474 Link: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/09681
Proper citation: National Long Term Care Survey (RRID:SCR_008943) Copy
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