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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Bamtools
 
Resource Report
Resource Website
100+ mentions
Bamtools (RRID:SCR_015987) software toolkit, software resource, software application, data management software, data analysis software, data processing software Software that provides both a C++ API and a command-line toolkit for reading, writing, and manipulating genome sequence alignment files in the BAM and SAM formats. It is used for research analysis and management of data produced by sequencing technologies. c++, api, sam, bam genome, sequence, alignment, data, analysis, management, command, manipulation, binary, map, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG004719;
NHGRI RC2 HG005552
PMID:21493652
DOI:10.1093/bioinformatics/btr174
biotools:bamtools, OMICS_11315 https://bio.tools/bamtools, https://sources.debian.org/src/bamtools/ SCR_015987 API:Application Programming Interface, BAM:Binary Alignment Map, SAM:Sequence Alignment Map 2026-08-08 12:00:45 344
ALTER
 
Resource Report
Resource Website
100+ mentions
ALTER (RRID:SCR_015968) web application, sequence analysis software, image analysis software, software resource, software application, data analysis software, alignment software, data processing software Web application to perform program-oriented conversion of DNA and protein alignments and transform between multiple sequence alignment formats. ALTER focuses on the specifications of mainstream alignment and analysis programs rather than on the conversion among more or less specific formats. Alignment conversion, genome, sequence, DNA, protein, format alignment, phylogenetics, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
European Research Council ERC-2007-Stg 203161-PHYGENOM to D.P.;
Spanish Ministry of Science and Education BFU2009-08611 to D.P.;
Xunta de Galicia PGIDIT07PXIB310202PR to D.P.;
INBIOMED initiative ;
University of Vigo 09VIB10 to F.F-.R.
PMID:20439312
DOI:10.1093/nar/gkq321
Freely available, Free, Available for download OMICS_19786, biotools:alter https://github.com/sing-group/ALTER, https://bio.tools/alter, https://sources.debian.org/src/alter-sequence-alignment/ SCR_015968 ALTER: ALignment Transformation EnviRonment, ALignment Transformation EnviRonment 2026-08-08 12:00:27 125
AMAP
 
Resource Report
Resource Website
100+ mentions
AMAP (RRID:SCR_015969) image analysis software, software resource, software application, source code, alignment software, data processing software Source code that performs multiple alignment of peptidic sequences. It utilizes posterior decoding and a sequence-annealing alignment, instead of the traditional progressive alignment method. software, peptide, sequence, alignment, annealing, bioinformatics, multiple, svn, posterior, decoding is listed by: Debian
is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
NSF EF 03-31494;
NHGRI R01 HG2362;
NSF CCF0347992
PMID:17237099
DOI:10.1093/bioinformatics/btl311
Free, Available for download OMICS_19787 http://baboon.math.berkeley.edu/amap/, https://sources.debian.org/src/amap-align/ https://sources.debian.org/src/amos-assembler/ SCR_015969 amap-align 2026-08-08 12:00:45 400
Aragorn
 
Resource Report
Resource Website
100+ mentions
Aragorn (RRID:SCR_015974) sequence analysis software, software resource, software application, data analysis software, data processing software Software that detects tRNA genes and tmRNA genes in nucleotide sequences. The program employs heuristic algorithms to predict tRNA secondary structure, based on homology with recognized tRNA consensus sequences and ability to form a base‐paired cloverleaf., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. software, program, nucleotide, sequence, detect, tmRNA, tRNA is listed by: Debian
is listed by: OMICtools
PMID:14704338
DOI:10.1093/nar/gkh152
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04227 https://sources.debian.org/src/arden/ SCR_015974 2026-08-08 12:00:46 474
Arden
 
Resource Report
Resource Website
10+ mentions
Arden (RRID:SCR_015975) software toolkit, image analysis software, software resource, software application, source code, alignment software, data processing software Software for specificity control of read alignments using an artificial reference. It estimates error rates based on real experimental reads and an additionally generated artificial reference genome. It can be used to optimize parameters for read mappers, to select read mappers for a specific problem or also to filter alignments based on quality estimation. software, alignment, artificial, reference, estimate, error, genome, false, positive, next, generation, sequencing, DNA, python is listed by: Debian
is listed by: OMICtools
Robert Koch-Institute (RKI) PMID:23685787
DOI:10.1093/bioinformatics/btt255
Free, Freely available OMICS_09783 https://sources.debian.org/src/ariba/ SCR_015975 ARDEN: Artificial Reference Driven Estimation of false positives in NGS data, Artificial Reference Driven Estimation of false positives in NGS data 2026-08-08 12:00:27 49
DIAMOND
 
Resource Report
Resource Website
100+ mentions
DIAMOND (RRID:SCR_016071) sequence analysis software, software resource, software application, data analysis software, data processing software Software that performs sequence alignment for protein and translated DNA searches and functions. Used for high performance analysis of big sequence data, protein-protein search, and DNA-protein search. sequence, aligner, high, performance, analysis, big, data, protein, DNA, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
has parent organization: University of Tubingen; Tubingen; Germany
PMID:25402007
DOI:10.1038/nmeth.3176
Free, Available for download OMICS_08011, biotools:diamond https://bio.tools/diamond, https://sources.debian.org/src/diamond-aligner/ SCR_016071 2026-08-08 12:00:48 489
Circlator
 
Resource Report
Resource Website
100+ mentions
Circlator (RRID:SCR_016058) software toolkit, image analysis software, software resource, software application, alignment software, data processing software Software that automates assembly circularization and produces accurate linear representations of circular sequences. It is used for assembling of DNA sequence data of complete bacterial and small eukaryotic genomes. assembly, sequence, genome, DNA, circularization, accurate, bacteria, erukaryote, tool is listed by: Debian
is listed by: OMICtools
Wellcome Trust grant 098051 PMID:26714481
DOI:10.1186/s13059-015-0849-0
Free, Available for download OMICS_09488 https://github.com/sanger-pathogens/circlator, https://sources.debian.org/src/circlator/ SCR_016058 2026-08-08 12:00:28 363
Clearcut
 
Resource Report
Resource Website
10+ mentions
Clearcut (RRID:SCR_016059) software resource, software application, standalone software, data visualization software, data processing software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023.Software as a stand-alone reference implementation for the Relaxed Neighbor Joining (RNJ) algorithm. Used in distance-based phylogenetic tree reconstruction method to process large sequence datasets., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. rnj, phylogenetic, tree, construction, neighbor, joining, distance, method, reference, standalone, implemetation, relaxed, algorithm, phylogenetic, tree, reconstruction, sequence is listed by: Debian
is listed by: OMICtools
is related to: University of Idaho; Idaho; USA
NIH P20 RR16448;
INBRE Program of the National Center for Research Resources ;
NSF EPS 00809035;
NIH P20 RR16454
PMID:16752216
DOI:10.1007/s00239-005-0176-2
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_15083 https://github.com/ibest/clearcut, https://sources.debian.org/src/clearcut/ SCR_016059 2026-08-08 12:00:47 26
Nanopolish
 
Resource Report
Resource Website
100+ mentions
Nanopolish (RRID:SCR_016157) software resource, software application, data analysis software, data processing software Software package for signal-level analysis of Oxford Nanopore sequencing data. Signal level analysis, Oxford Nanopore, sequencing data, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Free, Available for download, Freely available OMICS_16545, biotools:nanopolish https://bio.tools/nanopolish, https://sources.debian.org/src/nanopolish/ SCR_016157 2026-08-08 12:00:29 477
HiLive
 
Resource Report
Resource Website
HiLive (RRID:SCR_016134) sequence analysis software, software resource, software application, data analysis software, data processing software Software tool for performing read mapping that maps Illumina HiSeq sequencer read alignments when they are produced. Used in Next Generation Sequencing in time critical, clinical applications. perform, read, mapping, sequence, alignment, analysis, Illumina, time, critical, clinical, application is listed by: Debian
is listed by: OMICtools
the German Federal Ministry of Health IIA5-2512-FSB-725 PMID:27794555 Free, Available for download OMICS_13393 https://sources.debian.org/src/hilive/ https://sourceforge.net/projects/hilive/ SCR_016134 2026-08-08 12:00:29 0
FSA
 
Resource Report
Resource Website
1+ mentions
FSA (RRID:SCR_016114) FSA image analysis software, software resource, software application, alignment software, data processing software Software for a statistical multiple sequence alignment algorithm which uses a "distance-based" approach to align homologous protein, RNA or DNA sequences. The GUI, MAD (Multiple Alignment Display), can display the intermediate alignments produced by FSA, where each character is colored according to the probability that it is correctly aligned. multiple, sequence, alignment, algorithm, distance, approach, homologous, protein, DNA, RNA, acurate, fast is listed by: Debian
is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
PMID:19478997 Free, available for download https://sources.debian.org/src/fsa/ SCR_016114 Fast Statistical Alignment, FSA: Fast Statistical Alignment 2026-08-08 12:00:28 3
GARLI
 
Resource Report
Resource Website
100+ mentions
GARLI (RRID:SCR_016117) GARLI software resource, software application, data analysis software, data processing software Software application for inferring phylogenetic trees and analysis of molecular sequence data using the maximum-likelihood criterion. It implements nucleotide, amino acid and codon-based models of sequence evolution. inference, phylogenetic, tree, analysis, molecular, sequence, data, maximum, likelihood, criterion, nucleotide, amino acid, codon, model, evolution is listed by: Debian
is listed by: OMICtools
Free, Available for download, Freely available OMICS_04234 https://code.google.com/archive/p/garli/, https://sources.debian.org/src/garli/ SCR_016117 Genetic Algorithm for Rapid Likelihood Inference 2026-08-08 12:00:28 280
Fsm-lite
 
Resource Report
Resource Website
10+ mentions
Fsm-lite (RRID:SCR_016115) software resource, software application, data analysis software, data processing software Software application as a single-core implementation of frequency-based substring mining. It can be used in bioinformatics to extract substrings that discriminate two (or more) datasets inside high-throughput sequencing data. protein, dna, rna, sequence, analysis, core, implementation, frequency, based, substring, mining, extract, discriminate, dataset, sequencing, high throughput is listed by: Debian
is listed by: OMICtools
Free, Available for download OMICS_28406 https://sources.debian.org/src/fsm-lite/ SCR_016115 fsm, Frequency-based String Mining, Frequency-based String Mining (lite) 2026-08-08 12:00:48 19
gdpc
 
Resource Report
Resource Website
gdpc (RRID:SCR_016119) software resource, software application, data visualization software, data processing software Software application for visualizing output data from molecular dynamics simulations. It can be customized to read almost any input file format, animate it, and output images of each frame. visualizing, output, data, molecular, dynamic, simulation, animation, visualization is listed by: Debian
is listed by: OMICtools
Free, Available for download, Freely available OMICS_19946 https://sources.debian.org/src/gdpc/ http://www.frantz.fi/software/gdpc.php, https://directory.fsf.org/wiki/Gdpc SCR_016119 2026-08-08 12:00:49 0
Edtsurf
 
Resource Report
Resource Website
1+ mentions
Edtsurf (RRID:SCR_016083) software resource, software application, source code, data visualization software, data processing software Software that constructs triangulated surfaces for macromolecules. It generates three major macromolecular surfaces: van der Waals surface, solvent-accessible surface and molecular surface (solvent-excluded surface) and also identifies cavities which are inside of macromolecules. Used in accurate calculation of protein surfaces in the protein structural and functional studies including ligand-protein docking and virtual screening. construct, triangulate, surface, macromolecule, van der Waals, solvent, accessible, molecular, cavities, program is listed by: Debian
is listed by: OMICtools
the Alfred P. Sloan Foundation ;
NIGMS GM083107;
NIGMS GM084222;
NSF 0746198
PMID:19956577 Free, Available for download, Freely available OMICS_16795 https://sources.debian.org/src/edtsurf/ SCR_016083 EDTSurf: Quick and accurate construction of macromolecular surfaces 2026-08-08 12:00:28 4
E-mem
 
Resource Report
Resource Website
10+ mentions
E-mem (RRID:SCR_016081) E-mem image analysis software, software resource, software application, standalone software, alignment software, data processing software Software for an efficient maximal exact match (MEM) computation program that does not use full text indexes, uses less space and is amenable to parallelization. It can be used as a stand alone application or a drop-in replacement for MUMmer3 system for rapidly aligning entire genomes. efficient, maximal, exact, match, compute, program, algorithm, application, sequence, alignment is listed by: Debian
is listed by: OMICtools
has parent organization: Department of Computer Science; University of Western Ontario; London; Ontario; Canada
Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery Grant R3143A01 (L.I.). PMID:25399029 Free, Available for download OMICS_08451 https://github.com/lucian-ilie/E-MEM, https://sources.debian.org/src/e-mem/ SCR_016081 E-mem: Efficient-maximal exact match 2026-08-08 12:00:48 12
GenomeTools
 
Resource Report
Resource Website
100+ mentions
GenomeTools (RRID:SCR_016120) sequence analysis software, software toolkit, software resource, software application, data analysis software, data processing software Software toolkit for biological sequence analysis and -presentation combined into a single binary. It is used for genome analysis, efficient processing of structured genome annotations and contains binaries for sequence and annotation handling, sequence compression, index structure generation and access, annotation visualization. analysis, genome, annotate, sequence, compress, visualization, single, binary, combine, structure, efficient is listed by: Debian
is listed by: OMICtools
PMID:24091398 Free, Available for download OMICS_16119 https://sources.debian.org/src/genometools/ SCR_016120 GenomeTool, Genome Tools, Genome Tool 2026-08-08 12:00:28 150
bioSyntax
 
Resource Report
Resource Website
1+ mentions
bioSyntax (RRID:SCR_016207) data management software, software resource, software application Software for syntax highlighting for computational biology. computation, syntax, language, code, scientific, data, workflow, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
DOI:10.1186/s12859-018-2315-y Free, Available for download biotools:biosyntax, OMICS_25594 https://github.com/bioSyntax/bioSyntax, https://bio.tools/biosyntax, https://sources.debian.org/src/biosyntax/ SCR_016207 2026-08-08 12:00:50 2
lilikoi
 
Resource Report
Resource Website
1+ mentions
lilikoi (RRID:SCR_016361) software toolkit, software resource, software application, data analysis software, data processing software Software tool as an R package for personalized pathway-based classification modeling using metabolomics data. Provides personalized pathway deregulation measurements (PDS scores) and offers a standardized classification model for biomarker prediction. personalized, medicine, metabolomics, data, classification, clustering, biomarker, prediction, algorithm, calculating, microarray, enrichment is listed by: OMICtools
is related to: University of Hawaii; Hawaii; USA
NIEHS K01 ES025434;
NIGMS GM103457;
NLM R01 LM012373;
NICHD R01 HD084633
DOI:https://doi.org/10.1101/283408 Free, Available for download, Freely available https://omictools.com/lilikoi-tool SCR_016361 2026-08-08 12:00:30 3
AbundantOTU+
 
Resource Report
Resource Website
1+ mentions
AbundantOTU+ (RRID:SCR_016527) AbundantOTU sequence analysis software, software resource, software application, data analysis software, data processing software Software tool for analysis of large 16S rRNA pyrosequences by using a consensus alignment algorithm, utilizing the sequence redundancy of abundant species in the pyrosequence dataset. pyrosequencing, 16S, rRNA, gene, operational, taxonomic, unit, abundant, species, dataset is listed by: OMICtools
has parent organization: Indiana University; Indiana; USA
NHGRI R01 HG004908;
NHLBI U01 HL09896001
PMID:22102981 Free, Available for download, Freely available SCR_016527 AbundantOTU:Abundant Operational Taxonomic Unit, Abundant OTU, AbundantOTU+ 2026-08-08 12:00:32 1

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