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http://www.scienceexchange.com/facilities/chemodiversity-laboratory-cddi

The chemodiversity core facility offers a library of natural product-derived crude extracts, fractions and pure compounds for screening. Gas chromatography high-resolution mass spectrometry (MS) analysis, liquid chromatography MS targeted separation and high throughput screening (targeting solid tumor cell lines, anti-microbial activity, permeability and drug solubility determination) are provided. The services also include general chromatography (MPLC, HPLC) and spectrometric characterization (UV, IR) as well as microbiology workspace (biosafety cabinets), synthesis activities and training. Our facility offers advanced instrumentation (GC/MS Q-TOF, IR, UV, MPLCs, HPLCs, liquid handling robots, biosafety cabinets, and other essential lab equipment), consultation and services for sample isolation and analysis, derivatization and scale-up. Sample preparation and safety training are also available for commercial and USF clients using our chromatographic and analytical instrumentation.

Proper citation: USF Chemodiversity Laboratory (RRID:SCR_012262) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mass-spectrometry-biological-applications-and-high-throughput-proteomics-facility-cddi

The Mass Spectrometry, Biological Applications and High-Throughput Proteomics Facility is dedicated to the identification and quantification of components associated with complex biological matrices. The main goal of our lab is to produce high quality data related to any biological or environmental sample, i.e. cancer, Alzheimer_������_s, diabetes, cardiovascular disease, and parasitology, to name a few. To see a full list of facility activity, please visit our listed website.

Proper citation: USF Mass Spectrometry Biological Applications and High-Throughput Proteomics Facility (RRID:SCR_012261) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/mcgill-spr-facility

For applications including proteomics, drug discovery, immunogenicity, and food analysis, state-of-the-art Surface Plasmon Resonance (SPR) technology allows for label-free, real-time biomolecular interaction analysis. Using purified preparations or complex mixtures, binding interactions between proteins, lipids, carbohydrates, nucleic acids, small molecules, and cells/viruses can be examined quantitatively in their native state with low sample consumption. In a typical experiment, the ligand (_������������bait_������_) is immobilized to a gold-plated sensor chip and repeated injections of analyte (binding partner _������������target_������_) are then flowed overtop.

Proper citation: McGill SPR Facility (RRID:SCR_012265) Copy   

•   Source: SciCrunch Registry

https://www.usf.edu/arts-sciences/departments/chemistry/research/core-facilities/nmr.aspx

NMR facility provides state-of-the-art ultra-high field (14 and 18 Tesla) instruments that enable researchers to characterize protein structure at atomic resolution (along with the characterization of small molecules). Technical support and training are available for all aspects of project development. Experiments include structure elucidation of small molecules (e.g. synthetic molecules, natural products, and small peptides etc.) to studying advanced protein-ligand interactions.

Proper citation: USF NMR Laboratory (RRID:SCR_012260) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/nuclear-magnetic-resonance-facility--2

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 15,2024. Nuclear Magnetic Resonance Facility (NMR) was established in 2004. The Facility recognizes the important role that NMR plays in molecular structure determination, drug design, protein and nucleic acid characterization, and conformational analysis. The instrumentation serves the high-resolution research needs for investigators from the Departments of Molecular and Cell Biology, Chemistry, and Pharmacy at the University of Connecticut.

Proper citation: UConn Nuclear Magnetic Resonance Facility (RRID:SCR_012347) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/biophysical-analysis-lab-purdue

The purpose of the Biophysical Analysis Lab (BAL) at the Bindley Biosciences Center is to provide complete biophysical analysis of macromolecules. In the lab, there are two analytical ultracentrifuges: Beckman-Coulter XLI and XLA, a Biacore 3000, an ITC, and a SEC-MALS platform. With these instruments we can determine kinetic parameters, stoichiometry of binding, size distribution, shape, oligomerization state and other biophysical measurements. Complementing these traditional biophysical methods, the BAL also provides mass spectrometric analyses at both the protein and peptide levels. The lab strives to establish long-term collaborations and deliver professional quality data that can be used for publications and grant proposals.

Proper citation: Purdue Biophysical Analysis Lab (RRID:SCR_012349) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/protein-x-ray-crystallography-facility

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Protein X-ray Crystallography Facility became operational in October 2010 following the acquisition of a Rigaku HighFlux HomeLab system with funding awarded by the VPR''s Major Equipment Competition in November 2009.

Proper citation: UConn Protein X-Ray Crystallography Facility (RRID:SCR_012348) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bionet-academic-health-center-ahc

BioNet serves the University of Minnesota''''s Academic Health Center (AHC) as a centralized biorepository and bioregistry for patient consent and for the collection, processing, and distribution of de-identified tissue samples, blood and body fluids, purified DNA and specimen-matched clinical data for research. BioNet is becoming a major translational research resource linking clinical medicine, pathology, and basic and applied research to facilitate high quality and cost-conscious clinical and translational research. BioNet leverages the strengths of the Cancer Center''''s Tissue Procurement Facility (TPF), which has become part of BioNet. BioNet currently provides: * an optimized consenting process, * collection of tissue, blood, and fluid samples, * computerized specimen tracking systems that link -specimens to clinical data and other databases, * addition of core pathologist-supported facilities for histologic interpretation, immunohistochemistry, laser capture microdissection, and slide digitalization.

Proper citation: University of Minnesota Bionet - Academic Health Center (RRID:SCR_012469) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/anti-infectives-screening-and-insectary-core-facilities-nyu

Our insectary produces five rodent malaria strains weekly and will ship live sporozoite infected Anopheles stephensi to investigators for research use (Plasmodium berghei GFP, luciferase or red-star and P. yoelii-GFP) Anti-infective testing including in vitro EC50, in vivo mice infection are available against for major parasitic diseases: Malaria, Leishmaniasis, Chagas and African Trypanosomiasis.

Proper citation: NYU Anti-Infectives Screening and Insectary Core Facilities (RRID:SCR_012350) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/proteomics/index.php

Provides LCMS/MS analysis of proteins in clinical, environmental and other biological samples. As a shared facility of the Bindley Bioscience Center (BBC) in Discovery Park of Purdue University, the facility enables both targeted and global analysis of proteins, their post-translational modifications and analysis of protein complexes and protein-protein interactions. Coupled with different chromatographic separation techniques, modern mass spectrometric instrumentation, and advanced scientific and bioinformatics expertise, the facility provides unique opportunities for researchers at Purdue and beyond to perform quantitative analysis of proteins in complex biological samples using both global, as well as, targeted proteomic approaches.

Proper citation: Purdue University Proteomics Core Facility (RRID:SCR_012351) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/pharmacology/index.php

Purdue Translational Pharmacology (PTP) facility provides in vivo pharmacological evaluation using porcine models. The facility is situated in the Purdue University School of Veterinary Medicine complex, which provides constant care and monitoring of the animals. The PTP uses unique penning systems to automate blood sampling and maintain a humane and stress free environment for test subjects. The PTP synergizes with the Metabolite Profiling Facility in the Bindley Bioscience Center, which facilitates the pharmacological analysis of blood samples collected.

Proper citation: Purdue Translational Pharmacology Core Facility (RRID:SCR_012354) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/flow-cytometry-cell-separation-facility-purdue

The Bindley Bioscience Flow Cytometry and Cell Separation Facility provides advanced cell and particle analysis and sorting using flow cytometry based technology. The facility also provides training in flow cytometry analysis and sorting techniques. The facility also provides expert consultation for assay and protocol development for flow cytometry analysis and cell separation.

Proper citation: Bindley Bioscience Flow Cytometry and Cell Separation Facility (RRID:SCR_012353) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/x-ray-crystallography-facility-purdue

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2024. The laboratory at Purdue is equipped with advanced instrumentation for small molecule crystallography. The main diffractometer is equipped with a micro-focus x-ray source to allow very small crystals (less than 0.1 mm) to be studied. Low temperature data collection is available to a temperature of 95K. The crystallographer has been at Purdue for over 26 years and is widely respected.

Proper citation: Purdue X-Ray Crystallography Facility (RRID:SCR_012356) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/bioscience/facilities/core/bioscience/index.php

Provides instruments and expertise needed to visualize molecules in preparations ranging from single cells to entire animals. All facility users receive individualized instrument training as well as project specific advice for optimal data acquisition. Consultation on sample preparation, image rendering, and data analysis are also available as our knowledge base permits.

Proper citation: Purdue University Bioscience Imaging Core Facility (RRID:SCR_012355) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/epigenome-center-data-production-facility-usc

Core conducts genome-scale epigenetic and genetic data production and analysis, technology development, and epigenomic and population-based genomic research.

Proper citation: University of Southern California Epigenome Center Data Production Facility (RRID:SCR_012476) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/centrillion-biosciences-inc

Centrillion offers a portfolio of genomic services to academic, clinical and industrial researchers. Core provides experimental design consultation, data production services, and bioinformatics analyses for a wide variety of genomic applications. Core offers access to next-gen sequencing, genotyping and bioinformatics analysis.

Proper citation: Centrillion Biosciences Inc. (RRID:SCR_012358) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/plateforme-snp-transcriptome-and-epigenomics

THIS RESOURCE IS NO LONGER IN SERVICE, documented on September 02, 2014. Core facility that plays an active role in the Loire Valley Region''s officially-accredited fields of competitive excellence: plant sciences, medicine and pharmacy, child-oriented research.

Proper citation: University of Angers Plateforme SNP Transcriptome and Epigenomics (RRID:SCR_012478) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-core-rochester

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Offers state-of-the-art Mass Spectrometry and Biomarker Separation and Analysis Services.

Proper citation: URMC Proteomics Core (RRID:SCR_012361) Copy   

•   Source: SciCrunch Registry

http://genepool.bio.ed.ac.uk/

The GenePool is a next-generation genomics and bioinformatics facility based within the School of Biological Sciences, The University of Edinburgh. Which offers collaborative access to DNA sequencing, genotyping and bioinformatics capabilities, using ABI 3730 Sanger, Illumina and Roche 454 technology platforms.

Proper citation: University of Edinburgh GenePool Next Generation Sequencing and Bioinformatics (RRID:SCR_012485) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/gene-targeting-and-transgenic-core-rochester

Currently, the Gene Targeting and Transgenic Core''s services include the production of mouse models using DNA microinjection and embryonic stem cell injection (from gene targeting in mouse ES cells to production of chimeric mice) methodologies. Additional services have included: various analytical techniques, embryo cryopreservation, rederivation of pathogen-free rodents, and assisted reproduction techniques (e.g., in vitro fertilization (IVF), superovulation, and embryo transfer). Specific strains, and alternative species and methods are considered when appropriate for individual research applications.

Proper citation: URMC Gene Targeting and Transgenic Core (RRID:SCR_012367) Copy   

•   Source: SciCrunch Registry