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http://www.ncbi.nlm.nih.gov/homologene

Automated system for constructing putative homology groups from complete gene sets of wide range of eukaryotic species. Databse that provides system for automatic detection of homologs, including paralogs and orthologs, among annotated genes of sequenced eukaryotic genomes. HomoloGene processing uses proteins from input organisms to compare and sequence homologs, mapping back to corresponding DNA sequences. Reports include homology and phenotype information drawn from Online Mendelian Inheritance in Man, Mouse Genome Informatics, Zebrafish Information Network, Saccharomyces Genome Database and FlyBase.

Proper citation: HomoloGene (RRID:SCR_002924) Copy   

•   Source: SciCrunch Registry

http://www.ncbi.nlm.nih.gov/protein

Databases of protein sequences and 3D structures of proteins. Collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

Proper citation: NCBI Protein Database (RRID:SCR_003257) Copy   

•   Source: SciCrunch Registry

http://t3db.org/

Database that combines detailed toxin data with comprehensive toxin target information. The database currently houses 3,053 toxins described by 32,276 synonyms, including pollutants, pesticides, drugs, and food toxins, which are linked to 1,670 corresponding toxin target records. Altogether there are 37,084 toxin, toxin target associations. (March 2014) Each toxin record (ToxCard) contains over 50 data fields and holds information such as chemical properties and descriptors, toxicity values, molecular and cellular interactions, and medical information. This information has been extracted from over 5,454 sources sources, which include other databases, government documents, books, and scientific literature. The focus of the T3DB is on providing mechanisms of toxicity and target proteins for each toxin. This dual nature of the T3DB, in which toxin and toxin target records are interactively linked in both directions, makes it unique from existing databases. It is also fully searchable and supports extensive text, sequence, chemical structure, and relational query searches

Proper citation: T3DB (RRID:SCR_002672) Copy   

•   Source: SciCrunch Registry

http://www.drugbank.ca/

Bioinformatics and cheminformatics database that combines detailed drug (i.e. chemical, pharmacological and pharmaceutical) data with comprehensive drug target (i.e. sequence, structure, and pathway) information.

Proper citation: DrugBank (RRID:SCR_002700) Copy   

•   Source: SciCrunch Registry

https://scicrunch.org/scicrunch/data/source/nlx_154697-11/search?q=*

A virtual database indexing video and other multimedia content from: NIH VideoCasting and Podcasting, JoVE: Journal of Visualized Experiments, The Guardian: Science Videos, Biointeractive, goCognitive, UCSF Laboratory for Visual Neuroscience, and Clarity resources.

Proper citation: Integrated Videos (RRID:SCR_003613) Copy   

•   Source: SciCrunch Registry

https://bams1.org/cells/list.php, https://bams1.org/cells/search_bams_ref.php, https://bams1.org/cells/search_by_brain_region.php

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 6, 2023.BAMS is an online resource for information about neural circuitry. The BAMS Cell view focuses on the major brain regions and which cells are contained therein.

Proper citation: BAMS Cells (RRID:SCR_003531) Copy   

•   Source: SciCrunch Registry

https://confluence.crbs.ucsd.edu/display/NIF/DRG

Gene expression data from published journal articles that test hypotheses relevant to neuroscience of addiction and addictive behavior. Data types include effects of particular drug, strain, or knock out on particular gene, in particular anatomical region. Focuses on gene expression data and exposes data from investigations using DNA microarrays, polymerase chain reaction, immunohistochemistry and in-situ hybridizations. Data are available for query through NIF interface.Data submissions are welcome.

Proper citation: Drug Related Gene Database (RRID:SCR_003330) Copy   

•   Source: SciCrunch Registry

http://hendrix.imm.dtu.dk/services/jerne/brede/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 4th, 2023. A database of human data from functional neuroimaging scientific articles containing Talairach coordinates that provides data for novel information retrieval techniques and automated meta-analyses. Each article in this database is identified by a unique number: A WOBIB. Some of the structure of the Brede database is similar to the structure of the BrainMap database (Research Imaging Center, San Antonio). The database is inspired by the hierarchical structure of BrainMap with scientific articles (bib structures) on the highest level containing one or more experiments (exp structure, corresponding to a contrast in general linear model analyses), these in turn comprising one or more locations (loc structures). The information on the bib level (author, title, ...) is setup automatically from PubMed while the rest of the information is entered manually in a Matlab graphical user interface. On the loc level this includes the 3D stereotactic coordinates in either Talairach or MNI space, the brain area (functional, anatomical or cytoarchitectonic area) and magnitude values such as Z-score and P-value. On the exp level information such as modality, scanner and behavioral domain are recorded with external components (such as face recognition or kinetic boundaries) organized in a directed graph and marked up with Medical Subject Headings (MeSH) where possible. The database is distributed as part of the Brede neuroinformatics toolbox (hendrix.imm.dtu.dk/software/brede/) which also provides the functions to manipulate and analyze the data. The Brede Toolbox is a program package primarily written in Matlab. As of 2006/11, 186 papers with 586 experiments.

Proper citation: Brede Database (RRID:SCR_003327) Copy   

•   Source: SciCrunch Registry

http://blogs.scientificamerican.com/cross-check/

Every week, John Horgan takes a puckish, provocative look at breaking science. A former staff writer at Scientific American, he is the author of four books, the most recent of which is The End of War (to be published by McSweeney''s Books January 17, 2012). He currently directs the Center for Science Writings at Stevens Institute of Technology. He lives in New York State''s Hudson Highlands, where he plays ice hockey each winter to hone his cross-checking skills.

Proper citation: Scientific American Cross-Check (RRID:SCR_004266) Copy   

•   Source: SciCrunch Registry

https://scicrunch.org/scicrunch/data/source/nlx_154697-10/search?q=*&l=

A virtual database currently indexing software and tools from the SciCrunch Registry, Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC), Visiome Platform, Cerebellar Platform, Brain Machine Interface Platform, and Genetic Analysis Software (GAS).

Proper citation: Integrated Software (RRID:SCR_004745) Copy   

•   Source: SciCrunch Registry

http://crcns.org

Website for brain experimental data and other resources such as stimuli and analysis tools. Provides marketplace and discussion forum for sharing tools and data in neuroscience. Data repository and collaborative tool that supports integration of theoretical and experimental neuroscience through collaborative research projects. CRCNS offers funding for new class of proposals focused on data sharing and other resources.

Proper citation: CRCNS (RRID:SCR_005608) Copy   

•   Source: SciCrunch Registry

http://www.ncbi.nlm.nih.gov/clinvar/

Archive of aggregated information about sequence variation and its relationship to human health. Provides reports of relationships among human variations and phenotypes along with supporting evidence. Submissions from clinical testing labs, research labs, locus-specific databases, expert panels and professional societies are welcome. Collects reports of variants found in patient samples, assertions made regarding their clinical significance, information about submitter, and other supporting data. Alleles described in submissions are mapped to reference sequences, and reported according to HGVS standard.

Proper citation: ClinVar (RRID:SCR_006169) Copy   

•   Source: SciCrunch Registry

http://www.ncbi.nlm.nih.gov/pubmedhealth/

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 9, 2022. A consumer health database that provides up-to-date information on diseases, conditions, injuries, drugs, supplements, treatment options, and healthy living, with a special focus on comparative effectiveness research from institutions around the world. PubMed Health includes * consumer guides summarizing comparative effectiveness research * fact sheets on diseases and conditions * information on drugs and supplements * encyclopedic overviews of health topics * links to external Web sites PubMed Health has a special focus on comparative effectiveness research, in particular that research which evaluates the available evidence of the benefits and harms of different treatment options for different groups of people. In Comparative Effectiveness Research, experts often synthesize the evidence from dozens, or even hundreds, of individual studies.

Proper citation: PubMed Health (RRID:SCR_000512) Copy   

•   Source: SciCrunch Registry

http://brancusi.usc.edu/bkms/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 7th, 2019. BAMS is an online resource for information about neural circuitry. The BAMS Nested Regions view focuses on the major brain regions and their relationships.

Proper citation: BAMS Nested Regions (RRID:SCR_000238) Copy   

•   Source: SciCrunch Registry

http://cenblog.org/

Blogs for all things chemistry, hosted by Chemical & Engineering News (C&EN) magazine, where you will find blogs written by both C&EN staff and non-staff contributors on topics ranging from jobs to natural products chemistry to safety to the businesses of chemistry. CENtral Science currently includes the following blogs: * Artful Science: C&EN science writer Sarah Everts peers in to the laboratories that help museums and galleries authenticate, conserve, and restore art and artifacts. * Cleantech Chemistry: C&EN business writer Melody Voith looks at the business and technology strategies of companies that hope to serve the world's need for renewable energy, sustainable agriculture, clean water, and non-polluting manufacturing and transportation, among other cleantech sectors. * IYC 2011: CENtral Science's home for all things IYC 2011. * Just Another Electron Pusher: Contributors Christine Herman and Glenn Ernst profile people who've pursued professions away from the bench. They also write about their own personal quests for satisfying jobs that use their degrees but may not involve running any %$@& columns. * Newscripts: The companion blog to the like-named weekly C&EN column. Written primarily by C&EN science writers Lauren Wolf and Beth Halford, with contributions from the C&EN staff. * Terra Sigillata: Molecular cancer pharmacologist David Kroll writes about natural products, focusing on chemistry and pharmaceutical issues. * The Chemical Notebook: C&EN business writer Alex Tullo shares interesting tidbits from his reporter's notebook. * The Editor's Blog: The companion blog to the weekly print column by editor-in-chief Rudy Baum and deputy editor-in-chief Maureen Rouhi. * The Haystack: C&EN business writer Lisa Jarvis and science writer Carmen Drahl weed through pharma's molecular mountain to pluck out the drug developments worth noting. Also features frequent contributions from SeeArrOh, a Ph.D chemist working in industry. * The Safety Zone: C&EN science writer Jyllian Kemsley and safety consultant Russ Phifer cover chemical safety issues in academic and industrial research labs and in manufacturing. * Transition States: A blog about undergrads, by undergrads. Chiral Jones, a senior working on organic chemistry, and Sidechain Bob, a junior in the field of chemical biology, tell their stories of the graduate school experience. Over time, some blogs will retire and others will be added. Their blog network is intentionally a small one, and bloggers are added on an invitation basis. Proposals or blog suggestions may be submitted. It's not a community without your voice, so please contribute either as a commenter or a blogger.

Proper citation: CENtral Science (RRID:SCR_000652) Copy   

•   Source: SciCrunch Registry

http://www.wired.com/wiredscience/

Wired Science covers what's new on the front lines of science, from deep space to DNA sequencing.

Proper citation: Wired Science (RRID:SCR_000649) Copy   

•   Source: SciCrunch Registry

http://genomics.senescence.info/species/

Curated database of aging and life history in animals, including extensive longevity records and complementary traits for > 4000 vertebrate species. AnAge was primarily developed for comparative biology studies, in particular studies of longevity and aging, but can also be useful for ecological and conservation studies and as a reference for zoos and field biologists.

Proper citation: anage (RRID:SCR_001470) Copy   

•   Source: SciCrunch Registry

https://neuinfo.org/about/nifblog

Blog put out by the Neuroscience Information Framework covering a variety of neuroscience related topics including topics encountered by the Neuroscience Information Framework as a project.

Proper citation: NIF Blog (RRID:SCR_001651) Copy   

•   Source: SciCrunch Registry

https://www.ebi.ac.uk/chebi/beta/

Collection of chemical compounds and other small molecular entities that incorporates an ontological classification of chemical compounds of biological relevance, whereby the relationships between molecular entities or classes of entities and their parents and/or children are specified. The molecular entities in question are either products of nature or synthetic products used to intervene in the processes of living organisms.

Proper citation: CHEBI (RRID:SCR_002088) Copy   

•   Source: SciCrunch Registry

http://www.uniprot.org/help/uniprotkb

Central repository for collection of functional information on proteins, with accurate and consistent annotation. In addition to capturing core data mandatory for each UniProtKB entry (mainly, the amino acid sequence, protein name or description, taxonomic data and citation information), as much annotation information as possible is added. This includes widely accepted biological ontologies, classifications and cross-references, and experimental and computational data. The UniProt Knowledgebase consists of two sections, UniProtKB/Swiss-Prot and UniProtKB/TrEMBL. UniProtKB/Swiss-Prot (reviewed) is a high quality manually annotated and non-redundant protein sequence database which brings together experimental results, computed features, and scientific conclusions. UniProtKB/TrEMBL (unreviewed) contains protein sequences associated with computationally generated annotation and large-scale functional characterization that await full manual annotation. Users may browse by taxonomy, keyword, gene ontology, enzyme class or pathway.

Proper citation: UniProtKB (RRID:SCR_004426) Copy   

•   Source: SciCrunch Registry