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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
APID Interactomes (Agile Protein Interactomes DataServer) provides information on the protein interactomes of numerous organisms, based on the integration of known experimentally validated protein-protein physical interactions (PPIs). The interactome data includes a report on quality levels and coverage over the proteomes for each organism included. APID integrates PPIs from primary databases of molecular interactions (BIND, BioGRID, DIP, HPRD, IntAct, MINT) and also from experimentally resolved 3D structures (PDB) where more than two distinct proteins have been identified. This collection references protein interactors, through a UniProt identifier.
Proper citation: Agile Protein Interactomes DataServer (RRID:SCR_008871) Copy
http://www.mcmillenfoundation.org/
A foundation that offers grants for researchers in cardiology, lipid and organ transplant in Washington and Alaska. The Robert B McMillen Foundation is a non-profit charitable foundation established to; promote research in the areas of cardiology, lipid and organ transplant, support education at the university and college level in the states of Washington and Alaska and provide funding for social service organizations. What we fund: * MEDICAL: 50% of our annual giving is earmarked for medical research. We will consider making grants to non-profit organizations involved in researching cardiology, lipid and organ transplants. * EDUCATION: 25% of our annual giving is earmarked for Education at the University level in the states of Washington and Alaska. Funding will be provided to support the art departments of post secondary schools who offer a degree in the visual arts. * SOCIAL: 25% of our annual giving is earmarked for social areas including, but not limited to, Goodwill, Salvation Army & United Way. Preference is given to organizations and/or programs that use art as the vehicle to impact communities and change individual lives.
Proper citation: McMillen Foundation (RRID:SCR_008908) Copy
http://plantgrn.noble.org/LegumeIP/
LegumeIP is an integrative database and bioinformatics platform for comparative genomics and transcriptomics to facilitate the study of gene function and genome evolution in legumes, and ultimately to generate molecular based breeding tools to improve quality of crop legumes. LegumeIP currently hosts large-scale genomics and transcriptomics data, including: * Genomic sequences of three model legumes, i.e. Medicago truncatula, Glycine max (soybean) and Lotus japonicus, including two reference plant species, Arabidopsis thaliana and Poplar trichocarpa, with the annotation based on UniProt TrEMBL, InterProScan, Gene Ontology and KEGG databases. LegumeIP covers a total 222,217 protein-coding gene sequences. * Large-scale gene expression data compiled from 104 array hybridizations from L. japonicas, 156 array hybridizations from M. truncatula gene atlas database, and 14 RNA-Seq-based gene expression profiles from G. max on different tissues including four common tissues: Nodule, Flower, Root and Leaf. * Systematic synteny analysis among M. truncatula, G. max, L. japonicus and A. thaliana. * Reconstruction of gene family and gene family-wide phylogenetic analysis across the five hosted species. LegumeIP features comprehensive search and visualization tools to enable the flexible query on gene annotation, gene family, synteny, relative abundance of gene expression.
Proper citation: LegumeIP (RRID:SCR_008906) Copy
NeuroImaging laboratory focused on detecting early brain changes associated with cognitive decline and dementia that manages the neuroimaging component of all studies at the Layton Aging and Alzheimer's Center including acquisition and archival services, as well as volumetric analysis of anonymized MRI scans. Assistance with resulting data is also available, including statistical analysis, and preparation of materials for presentation and publication. The Layton Center also manages a library of thousands of digitized MRI scans, including what is believed to be the largest collection of longitudinal MRI scans of cognitively intact elderly subjects. The OADC Neuroimaging Lab conducts MRI studies on both 3 and 7T MRI systems using advanced sequences, employing a multimodal approach to brain imaging research.
Proper citation: Layton Center NeuroImaging Laboratory (RRID:SCR_008823) Copy
Aggregator of blogs about new developments in science and other fields that allows readers to easily find blog posts about serious peer-reviewed research, instead of just news reports and press releases. If you''re a blogger who writes about serious research, Research Blogging offers you a way to distinguish your serious posts from news, politics, family, bagpipes, and so on. They can direct your regular readers - and new readers - to the posts you''ve worked the hardest to create. All you need to get started is a blog and a peer-reviewed research report that you''d like to discuss. How it works * Bloggers -- often experts in their field -- find exciting new peer-reviewed research they''d like to share. They write thoughtful posts about the research for their blogs. * Bloggers register and use a simple one-line form to create a snippet of code to place in their posts. This snippet not only notifies this site about their post, it also creates a properly formatted research citation for their blog. * Their software automatically scans registered blogs for posts containing their code snippet. When it finds them, it indexes them and displays them on their front page -- thousands of posts from hundreds of blogs, in one convenient place, organized by topic. * Their editors identify the notable posts in each major discipline, publishing the results on their news page. * Other services like PubGet index their database as well, so every time readers search for a journal article, they can also locate blog posts discussing the article. * The quality of the posts listed on their site is monitored by the member bloggers. If a post doesn''t follow their guidelines, it is removed from their database. Borderline cases may be discussed publicly on the blog as well. Bloggers are also provided with an icon they can use to show when they''re talking about a peer-reviewed work that they''ve read and analyzed closely. There are already over seven thousand blog posts using the icon, and now it''s easier than ever to find them.
Proper citation: Research Blogging (RRID:SCR_008786) Copy
http://www.med.upenn.edu/cndr/biosamples-brainbank.html
A brain and tissue bank that contains human brain samples from patients with Alzheimer's disease (AD), Parkinson's disease (PD) and other related neurodegenerative dementias and movement disorders. This brain bank serves as a resource for scientists and researchers, providing access to tissue samples for further research. While priority is given to University of Pennsylvania researchers, this bank will provide requests to researchers not associated with the University of Pennsylvania. This tissue bank accepts donations from those seeing a University of Pennsylvania physician or collaborator.
Proper citation: University of Pennslyvania Brain Bank (RRID:SCR_008820) Copy
An online game for mapping neuronal connections in the retina. The site provides microscopic retinal images and uses crowdsourcing to make sense of the images. EyeWire is where the general public can help make discoveries about the neural structure of the retina. The challenge is to map the neural connections of the retina by analyzing images that were acquired using serial electron microscopy at the Max Planck Institute for Medical Research in Heidelberg, Germany. A retinal volume of size 350��300��60 micrometer cubed was imaged, amounting to about one terabyte of data. Retinal Connectome * Game 1: Reconstructing Neurons * Game 2: Identifying Synapses Eyewire incorporates computational technologies developed by the laboratory of Prof. Sebastian Seung at MIT.
Proper citation: EyeWire (RRID:SCR_008816) Copy
http://www.lifetechnologies.com/
Vendor for life sciences products and services ranging from instruments to antibodies.
Proper citation: Life Technologies (RRID:SCR_008817) Copy
http://www.alz.org/research/alzheimers_grants/overview.asp
An organization that funds research for Alzheimer's disease, provides information on new treatment strategies, provides information on caring for afflicted people, and generally increases public knowledge of disease prevention. This program financially supports new Alzheimer's studies. These research projects are selected by the Medical and Scientific Advisory Council. The council chooses which studies to address based on their potential uses in diagnostics, genetics, treatments, prevention, early detection and general enhancement of lifestyle.
Proper citation: Alzheimer's Association International Research Grant Program (RRID:SCR_008775) Copy
An endowment that offers funding for neuroscience research, especially as it may apply to Minnesota, agriculture, or if the researchers are based in Minnesota. The McKnight Foundation, a Minnesota-based family foundation, seeks to improve the quality of life for present and future generations through grantmaking, collaboration, and strategic policy reform in the following areas: arts, education and learning, environment, the region and communities, agricultural research, and neuroscience research. The McKnight Foundation assists nonprofit organizations and public agencies to improve the quality of life for all people, particularly those in need. Through grantmaking, coalition-building, and encouragement of strategic policy reform, we aim to build and maintain vibrant communities; enrich people''s lives through the arts; encourage protection of the natural environment; and promote research in selected fields. The Foundation had assets of approximately $1.8 billion and gave about $98 million in grants in 2009. Generally speaking, McKnight supports nonprofit organizations in Minnesota, U.S., only. McKnight''s primary geographic focus in grantmaking is to nonprofit organizations located within the state of Minnesota. We do not provide funding outside Minnesota, with five important programmatic exceptions: * Collaborative Crop research: International. * East Africa: Tanzania and Uganda only. * Mississippi River: 10 states bordering or encompassing the Mississippi River. * Neuroscience research: National. * Southeast Asia: Cambodia, Laos, and Vietnam only. Each program is different. Please consult the specific guidelines appropriate to your project or organization for funding details. With very few exceptions, McKnight funds nonprofit organizations only. To be eligible for a grant, applicants must be classified by the Internal Revenue Service as tax-exempt, nonprofit organizations. We discourage the use of fiscal agents.
Proper citation: McKnight Foundation (RRID:SCR_008776) Copy
http://www.mcknight.org/neuroscience/
An endowment that offers funding for memory research. The McKnight Endowment Fund for Neuroscience is an independent charitable organization established by The McKnight Foundation to carry out the wishes of its founder, William L. McKnight (1887-1979). Currently, the Endowment Fund for Neuroscience administers four awards which support young and established neuroscientists and encourage interdisciplinary collaboration: * Memory and Cognitive Disorders Awards * Neuroscience of Brain Disorders Awards * Scholar Awards * Technological Innovations in Neuroscience Awards Mr. McKnight, who led the 3M company for three decades, had a personal interest in memory and its diseases. He chose to set aside part of his legacy to bring hope to those suffering from brain injury or disease and cognitive impairment.
Proper citation: McKnight Endowment Fund for Neuroscience (RRID:SCR_008771) Copy
http://genome.ufl.edu/rivalab/pasta/
A complete pipeline for the analysis of alternative splicing using RNA-Sequencing data.
Proper citation: PASTA (RRID:SCR_008770) Copy
Platform for sharing data, with very large storage capability for electrophysiological data, EEG data is included. This service is provided for neuroscientists to facilitate data access, data storage, data analysis and data sharing. This service is developed and maintained by the German Node of the International Neuroinformatics Coordinating Facility. The global scale of neuroinformatics offers unprecedented opportunities for scientific collaborations between and among experimental and theoretical neuroscientists. To fully harvest these possibilities, coordinated activities are required to improve key ingredients of neuroscience: data access, data storage, and data analysis, together with supporting activities for teaching and training. Focusing on the development and free distribution of tools for handling and analyzing neurophysiological data, G-Node aims at addressing these aspects as part of the International Neuroinformatics Coordination Facility (INCF) and the German Bernstein Network for Computational Neuroscience (NNCN). G-Node also serves as an international forum for Computational Neuroscientists that are interested in sharing experimental data and tools for data analysis and modeling. G-Node is funded through the German Federal Ministry of Education and Research and hosted by Ludwig-Maximilians-Universit-Munchen.
Proper citation: G-node portal electrophysiology data sharing (RRID:SCR_008893) Copy
This comprehensive free collection of multimedia resources and inquiry-based activities tied to the National Science Education Standards help teachers and students learn about the structure, function and cognitive aspects of the human brain. The packet includes a teacher's manual, student manual, DVD of videos, and a CDROM of accompanying materials.
Proper citation: Brain's Inner Workings: Activities for Grades 9 through 12 (RRID:SCR_008842) Copy
http://en.wikibooks.org/wiki/Main_Page
Community wiki for an open-content textbooks collection that anyone can improve or add to, start new books, and join project-related discussions in the reading rooms. Contributors maintain the property rights to their contributions, while the Creative Commons Attribution-ShareAlike License and the GNU Free Documentation License makes sure that the submitted version and its derivative works will always remain freely distributable and reproducible. Categories include: Computing, Engineering, Humanities, Languages, Mathematics, Miscellaneous, Science, Social sciences, All subjects. Wikibooks has two sub-projects; Wikijunior which is aimed at children and the Cookbook which is a collection of recipes and culinary topics. * 2,440 books with 40,746 pages (March 2012)
Proper citation: Wikibooks (RRID:SCR_008799) Copy
http://www.raetschlab.org/suppl/qpalma
An alignment tool targeted to align spliced reads produced by Next Generation sequencing platforms such as Illumina Solexa or 454.
Proper citation: QPALMA (RRID:SCR_008791) Copy
Voluntary, non-profit organization dedicated to collecting and disseminating statistical data. Resource for gathering and disseminating epidemiologic data on all primary benign and malignant brain and other CNS tumors.
Proper citation: Central Brain Tumor Registry of the United States (RRID:SCR_008748) Copy
A tool for extraction and collaboration for data curation related to biology. CBioC runs as a web browser extension and allows unobtrusive use of the system during the regular course of research in PubMed. It can also be accessed directly (without having to install a plug-in). Automated text extraction is used as a starting point to bootstrap the database, but then it is up to biologists improve upon the extracted data, ironing out inconsistencies by subsequent edits on a massive scale. * After install, it loads when you visit PubMed. * Gets interactions from PubMed abstracts. * Allows you to vote and modify extracted data. * Also shows data from BIND, DIP, MINT, GRID, IntAct.
Proper citation: CBioC (RRID:SCR_008863) Copy
http://www.nature.com/npg_/index_npg.html
Nature Publishing Group (NPG) is a publisher of high impact scientific and medical information in print and online. NPG publishes journals, online databases and services across the life, physical, chemical and applied sciences and clinical medicine. Focusing on the needs of scientists, Nature (founded in 1869) is the leading weekly, international scientific journal. In addition, for this audience, NPG publishes the Nature research journals and Nature Reviews journals, plus a range of prestigious academic journals including society-owned publications. Online, nature.com provides over 6 million visitors per month with access to NPG publications and online databases and services, including news and comment from Nature, NatureJobs plus access to Nature Network and Nature Education''s Scitable.com. Scientific American is at the heart of NPG''s newly-formed consumer media division, meeting the needs of the general public. Founded in 1845, Scientific American is the oldest continuously published magazine in the US and the leading authoritative publication for science in the general media. Together with scientificamerican.com and 16 local language editions around the world it reaches over 3 million consumers and scientists. Other titles include Scientific American Mind and Spektrum der Wissenschaft in Germany. Scientific American is available for site license access on the nature.com platform. Throughout all its businesses NPG is dedicated to serving the scientific and medical communities and the wider scientifically interested general public. Part of Macmillan Publishers Limited, NPG is a global company with principal offices in London, New York and Tokyo, and offices in cities worldwide including Boston, Buenos Aires, Delhi, Hong Kong, Madrid, Barcelona, Munich, Heidelberg, Basingstoke, Melbourne, Paris, San Francisco, Seoul and Washington DC. Read our history for a timeline of NPG and the scientific events which have helped shape the direction of the business.
Proper citation: Nature Publishing Group (RRID:SCR_008741) Copy
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