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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Bioinformatics Toolkit
 
Resource Report
Resource Website
100+ mentions
Bioinformatics Toolkit (RRID:SCR_010277) software resource, software toolkit A platform that integrates a great variety of tools for protein sequence analysis. Many tools are developed in-house, and serveral public tools are offered with extended functionality. Most frequently used tools HHpred Sensitive protein homology detection and structure prediction by HMM-HMM-comparison. Starting from a query sequence, HHpred builds a multiple sequence alignment using HHblits and turns it into a profile HMM. This is then compared it with a database of HMMs representing proteins with known structure (e.g. PDB, SCOP) or annotated protein families (e.g. PFAM, SMART, CDD, COGs, KOGs). The output is a list of closest homologs with alignments. HHpred can also build 3d homology models using the identified templates in the PDB database. It can optimize template picking and query-template alignments for homology modeling. The HHblits software is part of the open source package HHsuite. HHblits Remote homology detection method based on iterative HMM-HMM comparison. HHblits can build high-quality MSAs starting from single sequences or from MSAs. It transforms these into a query HMM and iteratively searches through uniprot20 or nr20 databases by adding significantly similar sequences from the previous search to the updated query HMM for the next search iteration. Compared to PSI-BLAST, HHblits is faster, up to twice as sensitive and produces more accurate alignments. The HHblits software is part of the open source package HHsuite. Quick2d Quick2D gives you an overview of secondary structure features like alpha-helices, extended beta-sheets, coiled coils, transmembrane helices and disorder regions. Predictions by PSIPRED, JNET, Prof(Rost), Prof(Ouali), Coils, MEMSAT2, HMMTOP, DISOPRED2 and VSL2. Modeller A Program for Comparative Protein Structure Modelling by Satisfaction of Spatial Restraints. Coils/PCoils This server compares a single sequence (COILS) or a sequence alignment (PCOILS) to a database of known coiled-coils and derives a similarity score. The program then calculates the probability that the sequence will adopt a coiled-coil conformation. PSI-Blast Search with an amino acid sequence against protein databases for locally similar sequences. Similar to ProteinBLAST but more sensitive. PSI-BLAST first performs a BLAST search and builds an alignment from the best local hits. This alignment is then used as a query for the next round of search. After each successive round the search alignment is updated. bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
DOI:10.1038/NMETH.1818 nlx_156936, OMICS_28407, biotools:bioinformatics_toolkit https://bio.tools/bioinformatics_toolkit, https://sources.debian.org/src/hhsuite/ SCR_010277 2026-08-08 12:05:17 261
VISTA Browser
 
Resource Report
Resource Website
100+ mentions
VISTA Browser (RRID:SCR_011808) software resource, software toolkit Software tools for comparative genomics.Comprehensive suite of programs and databases for comparative analysis of genomic sequences. There are two ways of using VISTA - you can submit your own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species. Comparative genomics tools, genomic sequences, comparative analysis, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
Office of Biological and Environmental Research ;
Office of Science ;
US Department of Energy ;
NHLBI
PMID:15215394 Free, Freely available OMICS_00948, biotools:vista http://genome.lbl.gov/vista/index.shtml, https://bio.tools/vista SCR_011808 VISTA, vista 2026-08-08 12:05:19 125
NSeq
 
Resource Report
Resource Website
10+ mentions
NSeq (RRID:SCR_010891) NSeq software resource, software application A multithreaded Java application for finding positioned nucleosomes from sequencing data. is listed by: OMICtools OMICS_00506 SCR_010891 2026-08-08 12:05:14 12
Bioinformatics.fr
 
Resource Report
Resource Website
Bioinformatics.fr (RRID:SCR_011987) Bioinformatics.fr data or information resource, narrative resource A web magazine helping bioinformatician or scientists find jobs, conferences, courses, companies and more stuff related to Bioinformatics. bioinformatics is listed by: OMICtools OMICS_01728 SCR_011987 2026-08-08 12:05:15 0
BioCaster
 
Resource Report
Resource Website
1+ mentions
BioCaster (RRID:SCR_011869) BioCaster software resource, service resource Service that retrieves disease relevant information from Twitter tweets and shows current hotspots of disease outbreaks on an interactive map. It is an ontology-driven system for detecting global health events outbreak, pathogen, geographical location, latitude, longitude, map, text-mining, public health, health hazard, monitoring, twitter, global is listed by: OMICtools
has parent organization: National Institute of Informatics; Tokyo; Japan
is parent organization of: BioCaster Ontology
Infectious disease Japan Science and Technology Agency ;
Japan Society for the Promotion of Science ;
ROIS Transdisciplinary Integration Project
PMID:18922806 GNU General Public License OMICS_01174 SCR_011869 2026-08-08 12:05:08 3
Eucalyptus
 
Resource Report
Resource Website
10+ mentions
Eucalyptus (RRID:SCR_011872) Eucalyptus software resource, service resource Open source software for building AWS-compatible private and hybrid clouds for IT organizations in enterprises and technology businesses. cloud is listed by: OMICtools Open unspecified license OMICS_01202 SCR_011872 Elastic Utility Computing Architecture for Linking Your Programs to Useful Systems 2026-08-08 12:05:19 17
PRESTO: Genetic Association Analysis Software
 
Resource Report
Resource Website
1+ mentions
PRESTO: Genetic Association Analysis Software (RRID:SCR_013285) software resource, software application Software application that performs permutation testing and computes empirical distributions of order statistics for one and two stage association studies with stratified or unstratified data. gene, genetic, genomic, java, ms-windows, unix, solaris, linux, macos is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu138 nlx_154549 SCR_013285 2026-08-08 12:05:09 2
GoGrid
 
Resource Report
Resource Website
GoGrid (RRID:SCR_013204) GoGrid software resource, service resource Commercial software company offering on-demand cloud, hybrid hosting, hosted private cloud, and dedicated infrastructure for complex needs. cloud, big data is listed by: OMICtools OMICS_01203 SCR_013204 2026-08-08 12:05:20 0
THESIAS
 
Resource Report
Resource Website
50+ mentions
THESIAS (RRID:SCR_013449) THESIAS software resource, software application Software program that performs haplotype-based association analysis in unrelated individuals. This program is based on a maximum likelihood model described in Tregouet et al. 2002 and is linked to the stochastic EM (SEM) algorithm. THESIAS allows the simultaneous estimation of haplotype frequencies and of their associated effects on the phenotype of interest. In its current version, both quantitative and qualitative phenotypes can be studied. Covariate-adjusted haplotype effects as well as haplotype x covariate interactions can be investigated. (entry from Genetic Analysis Software) gene, genetic, genomic, ms-windows, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btm058 nlx_154102, OMICS_19747, biotools:tHESIAS https://bio.tools/THESIAS, https://sources.debian.org/src/thesias/ http://ecgene.net/genecanvas/downloads.php?cat_id=1 SCR_013449 Testing Haplotype EffectS In Association Studies 2026-08-08 12:05:10 53
PhyML
 
Resource Report
Resource Website
5000+ mentions
PhyML (RRID:SCR_014629) web application, software resource, source code Web phylogeny server based on the maximum-likelihood principle. phylogenic software, phylogeny, maximum likelihood, web server, bio.tools is used by: ProtTest
is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
works with: PAML
DOI:10.1093/molbev/msq060 Public server, Source code is available on request biotools:phyml, OMICS_04241 https://bio.tools/phyml, https://sources.debian.org/src/phyml/ SCR_014629 2026-08-08 12:05:22 7951
MultiQC
 
Resource Report
Resource Website
1000+ mentions
MultiQC (RRID:SCR_014982) software resource, data access protocol Data aggregate that compiles results from bioinformatics analyses across multiple samples into a single report. It is written in Python. bioinformatics, data aggregate, python, open source, html report, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Science for Life Laboratory ;
National Genomics Infrastructure
PMID:27312411
DOI:10.1093/bioinformatics/btw354
Open source, Available for download biotools:multiqc, OMICS_12426 https://github.com/ewels/MultiQC https://pypi.python.org/pypi/multiqc, https://bio.tools/multiqc, https://sources.debian.org/src/multiqc/ SCR_014982 2026-08-08 12:05:14 3714
Eagle
 
Resource Report
Resource Website
50+ mentions
Eagle (RRID:SCR_015991) software resource, software toolkit Software package for statistical estimation of haplotype phase either within a genotyped cohort or using a phased reference panel in large scale sequencing. The package includes Eagle1 (to harness identity-by-descent among distant relatives to rapidly call phase using a fast scoring approach) and Eagle2 (to analyze a full probabilistic model similar to the diploid Li-Stephens model used by previous HMM-based methods. hmm, hidden markov model, statistic, estimation, haplotype, phase, reference, panel, sequencing, algorithm, analysis, probability is listed by: Debian
is listed by: OMICtools
has parent organization: Broad Institute
NHGRI R01 HG006399;
NIMH R01 MH101244;
NHGRI F32HG007805;
Wellcome Trust WT098051;
Austrian Science Fund J-3401;
NHGRI HG007022;
NHLBI HL117626;
Fannie and John Hertz Foundation ;
NCRR S10 RR028832;
NWO 480-05-003;
Dutch Brain Foundation
PMID:27694958
PMID:27270109
Free, Available for download, Freely available OMICS_14099, SCR_017262 https://sources.debian.org/src/bio-eagle/, https://github.com/poruloh/Eagle, https://data.broadinstitute.org/alkesgroup/Eagle/downloads/ SCR_015991 Bio-eagle, Eagle1, Eagle2 2026-08-08 12:05:15 57
ABACAS
 
Resource Report
Resource Website
100+ mentions
ABACAS (RRID:SCR_015852) ABACAS software resource, software application Software that contiguates (align, order, orientate), visualizes and designs primers to close gaps on shotgun assembled contigs based on a reference sequence. ABACAS finds alignment positions and identifies syntenies of assembled contigs against the reference, then generates a pseudomolecule taking overlapping contigs and gaps into account. contiguation, primer, shotgun assembled contig, reference sequence, assembled sequence is listed by: Debian
is listed by: OMICtools
European Union LSHP-LT-2004-503578;
Wellcome Trust Sanger Institute
Free, Available for download OMICS_06933 https://sourceforge.net/projects/abacas/files/, https://sources.debian.org/src/abacas/ SCR_015852 ABACAS: Algorithm Based Automatic Contiguation of Assembled Sequences, Algorithm Based Automatic Contiguation of Assembled Sequences (ABACAS), Algorithm Based Automatic Contiguation of Assembled Sequences 2026-08-08 12:05:15 178
Ecopcr
 
Resource Report
Resource Website
10+ mentions
Ecopcr (RRID:SCR_016082) Ecopcr software resource, software application Software for Electronic PCR that estimates PCR barcode primers quality and develops new barcode primers. In conjunction with OBITools, users can postprocess ecoPCR output to compute barcode coverage and barcode specificity., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. electronic, PCR, estimate, primers, quality, barcode is listed by: Debian
is listed by: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_19861 https://sources.debian.org/src/ecopcr/ http://www.grenoble.prabi.fr/trac/ecoPCR/ SCR_016082 Ecopcr: Electronic polymerase chain reaction 2026-08-08 12:05:20 27
Concavity
 
Resource Report
Resource Website
50+ mentions
Concavity (RRID:SCR_016063) software toolkit, software resource, software application Software for predicting protein ligand binding sites that integrate evolutionary sequence conservation estimates with structure-based methods for identifying protein surface cavities. Used in predicting catalytic sites and drug binding pockets. predict, protein, ligand, binding, site, catalytic, drug, algorithm is listed by: Debian
is listed by: OMICtools
is related to: Princeton University; New Jersey; USA
PMID:19997483
DOI:10.1371/journal.pcbi.1000585
Free, Available for download OMICS_04161 http://manpages.ubuntu.com/manpages/bionic/man1/concavity.1.html, https://sources.debian.org/src/concavity/ SCR_016063 2026-08-08 12:05:24 94
Mash
 
Resource Report
Resource Website
50+ mentions
Mash (RRID:SCR_019135) software resource, data analytics software, software application Software tool for genome and metagenome distance estimation using MinHash. Reduces large sequences and sequence sets to small, representative sketches, from which global mutation distances can be rapidly estimated. Genome distance estimation, metagenome distance estimation, MinHash, mutation distance, sequence, sequence set is listed by: Debian
is listed by: OMICtools
NHGRI ;
NIH
PMID:27323842 Free, Available for download, Freely available OMICS_10468 https://mash.readthedocs.io/en/latest/, https://sources.debian.org/src/mash/ SCR_019135 2026-08-08 12:05:25 75
Scoary
 
Resource Report
Resource Website
10+ mentions
Scoary (RRID:SCR_021087) software resource, data analytics software, software application Software tool that scores components of pan genome for associations to observed phenotypic traits while accounting for population stratification, with minimal assumptions about evolutionary processes.Designed to take gene presence absence.csv file from Roary as well as traits file created by user and calculate associations between all genes in accessory genome and traits. It reports list of genes sorted by strength of association per trait. Gene associations calculation, accessory genome, phenotypic traits, gene presence, gene absence, gene sort, association strenght is listed by: Debian
is listed by: OMICtools
works with: Roary
Norwegian Institute of Public Health ;
Norwegian Research Council
PMID:27887642 Free, Available for download, Freely available OMICS_13120 https://sources.debian.org/src/scoary/ SCR_021087 2026-08-08 12:05:26 20
EpiFactors
 
Resource Report
Resource Website
10+ mentions
EpiFactors (RRID:SCR_016956) database, data or information resource Manually curated collection of human epigenetic factors, their complexes, corresponding genes and products. manually, curated, collection, human, epigenetic, factor, complex, corresponding, gene, target, product is listed by: OMICtools Russian Fund For Basic Research ;
Ministerio de Economia Y Competividad ;
Spain ;
Åke Olsson’s foundation ;
Swedish Cancer foundation ;
Swedish Childhood cancer foundation ;
Dynasty Foundation Fellowship ;
Japanese Ministry of Education ;
Culture ;
Sports ;
Science and Technology ;
Norwegian University of Science and Technology
PMID:26153137 Free, Available for download, Freely available SCR_016956 2026-08-08 12:04:40 24
miRTarBase
 
Resource Report
Resource Website
100+ mentions
miRTarBase (RRID:SCR_017355) database, data or information resource Web based manually curated experimentally validated database of microRNA-Target interactions. Collection of MTIs data validated experimentally by reporter assays, western blot, or microarray experiments with overexpression or knockdown of miRNAs. Manually, curated, experimentally, validated, database, microRNA, target, interaction, collection, data, MTI, FASEB list is listed by: OMICtools Ministry of Science and Technology ;
Taiwan
PMID:29126174 Free, Available for download, Freely availabe http://mirtarbase.mbc.nctu.edu.tw/php/index.php SCR_017355 microRNA-Target interactions Base 2026-08-08 12:04:34 432
Geno2MP
 
Resource Report
Resource Website
1+ mentions
Geno2MP (RRID:SCR_016872) Geno2MP database, data or information resource, service resource Collection of phenotypic profiles for affected individuals and, for unaffected individuals, the phenotypic profile of their affected. Collaborative, shared resource for the human genetics community. data, collection, Mendelian, phenotype, affected, individuals, profile, human, genetics is used by: MARRVEL
is listed by: OMICtools
University of Washington Center for Mendelian Genomics ;
Seattle ;
WA
Free, Available for download, Freely available SCR_016872 Geno2MP, 2 Mendelian Phenotype, The Genotype 2 Mendelian Phenotype database 2026-08-08 12:04:34 2

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