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https://www.med.upenn.edu/cores/assets/user-content/documents/HTSC_overview_27May2015.pdf

Core provides distribution of lentivirus based shRNA and cDNA plasmid DNA clones; technical expertise in developing biological assays (i.e. biochemical-, cell-, and high-content) in miniaturized, multiwell microtiter plates that are laboratory automation compatible; high-throughput chemical and functional genomic screening, including data analysis and interpretation. Our goal is to use cutting biological models to discover genes and small molecules that enable scientists to further study functions of poorly understood proteins, signaling pathways, and cells in complex biological process relevant to human physiology and disease.

Proper citation: University of Pennsylvania Perelman School of Medicine High Throughput Screening Core Facility (RRID:SCR_022379) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cvi/mouse-cardiovascular-phenotyping-core.html

Core provides services to assess cardiovascular function in mouse models and to provide validated surgical models of heart and vascular disease in mice to assess genetic or therapeutic interventions. Works with investigators to design and implement study along with any associated grant applications, animal protocol submissions and manuscript preparation. While central focus of facility is cardiovascular research, techniques employed are often useful to investigators in other fields. Helps to assess your needs and provide necessary technical training and scientific assistance in animal protocol preparation. Core runs on a fee for service model.�Accordingly, investigators will be responsible for costs incurred for their projects and prior animal protocol approval by Penn IACUC., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Mouse Cardiovascular Phenotyping Core Facility (RRID:SCR_022419) Copy   

•   Source: SciCrunch Registry

https://www.janelia.org/support-team/light-microscopy

Facility is open to Janelia scientists. Houses microscopes and multiple workstations dedicated to image processing.

Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Light Microscopy Core Facility (RRID:SCR_022103) Copy   

•   Source: SciCrunch Registry

https://cds.vanderbilt.edu

Shared Resource that offers bioinformatics and informatics services for basic research and clinical projects.

Proper citation: Vanderbilt University Creative Data Solutions Core Facility (RRID:SCR_022366) Copy   

•   Source: SciCrunch Registry

http://researchservices.pitt.edu/facilities/microscopy-and-imaging-suite

Facility equipped with instruments for optical and electron microscopy, and Flow Cytometry.Offers experimental design, equipment training, staff operated image acquisition, and image analysis. All users must be trained by Facility staff to access the equipment.

Proper citation: University of Pittsburgh Microscopy and Imaging Suite Core Facility (RRID:SCR_022084) Copy   

•   Source: SciCrunch Registry

https://www.umass.edu/ials/biophysical-characterization

Provides expertise and access to instruments for study of structures and interactions of biological macromolecules such as proteins, nucleic acids, lipids, and complexes. Facility supports both discovery based research and assay development for translational applications. Offers to use equipment independently or with the help of faculty who have expertise in each method.

Proper citation: University of Massachusetts Amherst Biophysical Characterization Core Facility (RRID:SCR_022357) Copy   

•   Source: SciCrunch Registry

https://qb3.berkeley.edu/facility/genomics/

Partnership between Vincent J. Coates Genomics Sequencing Laboratory,Functional Genomics Laboratory, and Computational Genomics Resource Laboratory. Offers consultation on experimental design and data analysis, full suite of technical services related to high throughput sequencing and genomics experiments, and access to high performance computational infrastructure.

Proper citation: University of California at Berkeley QB3 Genomics Core Facility (RRID:SCR_022170) Copy   

•   Source: SciCrunch Registry

http://www.mri.cnrs.fr

Cell imaging facility of Montpellier area, France.Offers access to cutting edge instruments for optical and electron microscopy, flow cytometry, and X-ray micro tomography. Instruments are housed in seven sites that mirror distribution of Life Science research campuses of the region. Mission is to support research by offering imaging instruments and image analysis solutions.

Proper citation: Montpellier Imagining Resources MRI Core Facility (RRID:SCR_022290) Copy   

•   Source: SciCrunch Registry

https://www.pedsresearch.org/research/cores/flow-cytometry-core/overview/

Core provides cytometry services for analysis and sorting of cells as well as expert consultation for experimental design and planning. Offers access to several analytical flow cytometers as well as high speed cell sorting. Training and technical expertise is available.

Proper citation: Emory University and Pediatric Winship Flow Cytometry Core Facility (RRID:SCR_022324) Copy   

•   Source: SciCrunch Registry

http://www.facs.au.dk

Facility is equipped with cell sorters, analyzers, ImageStream and full spectrum flow cytometer. Staff provides training and maintenance.

Proper citation: Aarhus University Fluorescence Activated Cell Sorting Core Facility (RRID:SCR_022323) Copy   

•   Source: SciCrunch Registry

https://vpr.tamu.edu/core_facility/high-throughput-research-and-screening-center/

Core provides industry standard high throughput screening and automated microscopy capabilities to scientists performing drug discovery research. Provides access to automated infrastructure to support phenotypic and biochemical targets. Provides ready access to collections of current FDA approved drugs and clinical candidates exhibiting drug like qualities of acceptable solubility, desirable ADME/toxicology properties and adequate bioavailability. Has collections of mechanistically annotated informer sets that are pathway specific modulators for studying mechanism of action or target identification, collections of natural products and diverse sets of small molecules that can be interrogated for new target discovery. Each project is individually evaluated and team of scientists from CDDP is created to fit specific needs of project from assay design and development through primary, secondary and orthogonal screening.

Proper citation: Texas A and M University Institute of Biosciences and Technology High Throughput Research and Screening Center Combinatorial Drug Discovery Core Facility (RRID:SCR_022214) Copy   

•   Source: SciCrunch Registry

http://csbio.unc.edu/CCstatus/index.py?run

Provides access to multi parental genetic reference mouse population derived from eight founder inbred strains, encompassing genetic diversity. Strains have been sequenced and have much genomic data. All of CC strains are kept as live mouse strains. Provides breeding stock for internal use unless other permission is acquired, or experimental cohorts.

Proper citation: University of North Carolina at Chapel Hill Systems Genetics Core Facility (RRID:SCR_022703) Copy   

•   Source: SciCrunch Registry

https://www.med.unc.edu/functionalgenomics/

Core performs expression profiling, SNP genotyping and copy number microarray (Thermo Fisher) services.

Proper citation: University of North Carolina at Chapel Hill Functional Genomics Core Facility (RRID:SCR_022702) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/live-cell-imaging-core/

Offers wide array of live cell imaging applications.Provides Nikon A1R Laser Scanning Confocal Microscopy system equipped with 4 laser lines to provide 6 different excitation/emission configurations; multiple photomultiplier tubes (PMTs), 32-channel spectral detector, full complement of microscope objectives, high speed image scanner, fully motorized stage and completely controllable environmental chamber. Users have access to NIS Elements AR software and 2D/3D deconvolution module offering sophisticated image analysis and processing features.

Proper citation: University of Pennsylvania Penn Dental Medicine Live Cell Imaging Core Facility (RRID:SCR_022442) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/transgenic-mouse-core

Offers embryological manipulation services, focused on, but not limited to, murine model systems. These services primarily enable generation of genetically modified murine models, as well as experimental research in germ cell function and early embryonic development.

Proper citation: University of Pennsylvania Penn Vet Transgenic Mouse Core Facility (RRID:SCR_022441) Copy   

•   Source: SciCrunch Registry

https://lipidomics.wayne.edu

Conducts comprehensive analysis of cellular lipids that encompass fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, and prenol lipids.

Proper citation: Wayne State University School of Medicine Lipidomics Core Facility (RRID:SCR_022682) Copy   

•   Source: SciCrunch Registry

http://cils.northeastern.edu/facilities

Located in ISEC research center and includes advanced imaging instruments. CILS has three core facilities: Microscopy Core (confocal/multi-photon/lightsheet microscopes), Flow Cytometry Core (cell analyzer/sorter) and Preclinical Imaging Core (3T small animal MRI and ultrasound).

Proper citation: Northeastern University Institute for Chemical Imaging of Living Systems Core Facility (RRID:SCR_022681) Copy   

•   Source: SciCrunch Registry

https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/

Provides secure environment for investigators analyzing protected health information. �It coordinates acquisition, storage, and analysis of data from private and government sources (e.g., Medicare, Medicaid, and others) and facilitates their use by researchers who seek to answer important questions regarding health policy and health care.�

Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Health Services Research Data Center Core Facility (RRID:SCR_022439) Copy   

•   Source: SciCrunch Registry

https://resnick.caltech.edu/research/resource-centers/water-and-environment-lab-wel

Provides access to chromatography and mass spectrometry techniques including GC and GC-MS, IC and IC-MS, ICP-MS, LC and LC-MS, and other environmentally relevent techniques such as isotope ratio measurements of water, TIC/TOC, and laser diffraction particle size analysis.

Proper citation: California Institute of Technology Water and Environment Laboratory Core Facility (RRID:SCR_022714) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/comparative-pathology-core

Provides support to investigators utilizing animal models to study disease. Comparative Pathology Core, Abramson Cancer Center shared resource, provides expert pathological characterization and validation of mouse and other animal models used in biomedical research by offering expertise of board certified veterinary pathologists and access to histology, immunohistochemistry, and digital pathology services.

Proper citation: University of Pennsylvania Penn Vet Comparative Pathology Core Facility (RRID:SCR_022438) Copy   

•   Source: SciCrunch Registry