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http://pgfe.umassmed.edu/ffs/

Database of Drosophila transcription factor DNA binding specificity using the bacterial one-hybrid method, DNase I or SELEX methods. The database provides community access to recognition motifs and position weight matrices for transcription factors (TFs), including many unpublished motifs. Search tools and flat file downloads are provided to retrieve binding site information (as sequences, matrices and sequence logos) for individual TFs, groups of TFs or for all TFs with characterized binding specificities. Linked analysis tools allow users to identify motifs within the database that share similarity to a query matrix or to view the distribution of occurrences of an individual motif throughout the Drosophila genome. This database and its associated tools provide computational and experimental biologists with resources to predict interactions between Drosophila TFs and target cis-regulatory sequences.

Proper citation: FlyFactorSurvey (RRID:SCR_002113) Copy   

•   Source: SciCrunch Registry

http://hertellab.mmg.uci.edu/cgi-bin/HEXEvent/HEXEventWEB.cgi

A free database that provides a list of human internal exons and reports all their known splice events based on EST information from the UCSC Genome Browser. This list can be restricted by the user to either only a specific region in the genome (by specifying the chromosome, the strand and the start and end position), to a whole chromosome or to a group of genes. Furthermore, exons can be filtered according to their splicing type (constitutive exons, cassette exons and exons with one or more alternative 3' and/or 5' splice sites). In order to extract a customized set of exons, the user-specific definitions of exon types can be fixed. The user needs to specify in what fraction of ESTs an exon is allowed to be alternatively spliced in order to still be called constitutive. Furthermore, the user can restrict the set of requested cassette exons by a certain upper inclusion level, which, for instance, is useful when only looking for low-inclusion exons.

Proper citation: HEXEvent (RRID:SCR_002106) Copy   

•   Source: SciCrunch Registry

http://www.bacteriome.org

Database integrating physical (protein-protein) and functional interactions within the context of an E. coli knowledgebase. Presently the resource offers access to two types of network: * A network of functional interactions derived through exploiting available functional genomic datasets within a Bayesian framework * Two networks of experimentally derived protein-protein interactions - a "core" network consisting of interactions deemed to be of "high quality"; and an "extended" network which extends the "core" network by including interactions for which experimental evidence is less strong.

Proper citation: Bacteriome.org (RRID:SCR_001934) Copy   

•   Source: SciCrunch Registry

http://blanco.biomol.uci.edu/membrane_proteins_xtal.html

Table providing information about integral membrane proteins whose crystallographic, or sometimes NMR, structures have been determined to a resolution sufficient to identify TM helices of helix-bundle membrane proteins (typically 4 - 4.5 angstroms). It is based upon Preusch et al. (1998) as revised by White & Wimley (1999). Reference is made to all of the protein types whose structures have been determined. They have attempted to make the database as inclusive as possible.

Proper citation: Mpstruct (RRID:SCR_013284) Copy   

•   Source: SciCrunch Registry

http://sourceforge.net/projects/cnvhitseq/

A set of Java-based command-line tools for detecting Copy Number Variants (CNVs) using next-generation sequencing data.

Proper citation: cnvHiTSeq (RRID:SCR_013160) Copy   

•   Source: SciCrunch Registry

http://aws.amazon.com/

IT infrastructure services for businesses in the form of web services, now commonly known as cloud computing. This highly reliable, scalable, low-cost infrastructure platform in the cloud powers hundreds of thousands of businesses. With data center locations in the U.S., Europe, Singapore, and Japan, customers across all industries are taking advantage of the following benefits: * Low cost * Agility and Instant Elasticity * Open and Flexible * Secure

Proper citation: Amazon Web Services (RRID:SCR_012854) Copy   

•   Source: SciCrunch Registry

https://sites.google.com/site/dchipsoft/

Software for analysis and visualization of gene expression and SNP microarrays.

Proper citation: dChip Software (RRID:SCR_013504) Copy   

•   Source: SciCrunch Registry

http://www.biogazelle.com/qbaseplus

Software program for quantitative PCR (qPCR) data analysis based on geNorm and qBase technology.

Proper citation: qBasePLUS (RRID:SCR_003370) Copy   

•   Source: SciCrunch Registry

https://github.com/neufeld/pandaseq

Software program to align Illumina reads, optionally with PCR primers embedded in the sequence, and reconstruct an overlapping sequence.

Proper citation: PANDAseq (RRID:SCR_002705) Copy   

•   Source: SciCrunch Registry

http://primerdigital.com/fastpcr.html

Software tool for PCR primers or probe design, in silico PCR, oligonucleotide assembly and analyses, alignment and repeat searching.

Proper citation: FastPCR (RRID:SCR_003155) Copy   

•   Source: SciCrunch Registry

http://cistrome.org/finder

Data portal that can help query, evaluate and visualize publicly available Chromatin immunoprecipitation and DNase I hypersensitivity assays with high-throughput sequencing data in human and mouse. The database currently contains 6378 samples over 4391 datasets, 313 factors and 102 cell lines or cell populations (May 2013). Each dataset has gone through a consistent analysis and quality control pipeline; therefore, users could evaluate the overall quality of each dataset before examining binding sites near their genes of interest. CistromeFinder is integrated with UCSC genome browser for visualization, Primer3Plus for ChIP-qPCR primer design and CistromeMap for submitting newly available datasets. It also allows users to leave comments to facilitate data evaluation and update.

Proper citation: CistromeFinder (RRID:SCR_005405) Copy   

•   Source: SciCrunch Registry

Ratings or validation data are available for this resource

http://broadinstitute.github.io/picard/

Java toolset for working with next generation sequencing data in the BAM format.

Proper citation: Picard (RRID:SCR_006525) Copy   

•   Source: SciCrunch Registry

http://www.biopieces.org

A collection of bioinformatics tools that can be pieced together in a very easy and flexible manner to perform both simple and complex tasks. The Biopieces work on a data stream in such a way that the data stream can be passed through several different Biopieces, each performing one specific task: modifying or adding records to the data stream, creating plots, or uploading data to databases and web services. The Biopieces are executed in a command line environment where the data stream is initialized by specific Biopieces which read data from files, databases, or web services, and output records to the data stream that is passed to downstream Biopieces until the data stream is terminated at the end of the analysis. The advantage of the Biopieces is that a user can easily solve simple and complex tasks without having any programming experience. Moreover, since the data format used to pass data between Biopieces is text based, different developers can quickly create new Biopieces in their favorite programming language - and all the Biopieces will maintain compatibility. Finally, templates exist for creating new Biopieces in Perl and Ruby. There are currently ~190 Biopieces (March 2014).

Proper citation: Biopieces (RRID:SCR_005783) Copy   

•   Source: SciCrunch Registry

http://www.leicabiosystems.com/index.php?id=9161

A high performance, intuitive client viewer with integrated reporting functionality that can be used as a standalone viewer for accessing slides locally, or connected to Digital Image Hub for remote review.

Proper citation: Slidepath (RRID:SCR_005597) Copy   

•   Source: SciCrunch Registry

http://www.geospiza.com/Products/finchtv.shtml

Chromatogram viewer that can display an entire trace in a scalable multi-pane view, allows raw data views, BLAST searching and the ability to reverse complement sequences and traces., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: FinchTV (RRID:SCR_005584) Copy   

•   Source: SciCrunch Registry

http://www.geneious.com/features/microsatellite-analysis

Free plugin that imports ABI fragment analysis ?les and allows you to visualize traces, ?t ladders, call peaks, predict bins, display alleles in a tabular format and export your data.

Proper citation: Geneious Microsatellite Plugin (RRID:SCR_005466) Copy   

•   Source: SciCrunch Registry

http://sourceforge.net/projects/phenofam/

A web-based application that performs gene set enrichment analysis (GSEA) by employing structural and functional information on families of protein domains as annotation terms.

Proper citation: PhenoFam (RRID:SCR_000640) Copy   

•   Source: SciCrunch Registry

http://iomics.us/

A genomics data analysis platform which generates decision models for healthcare organizations and medical research. This service is meant to utilize data through machine learning methods.

Proper citation: iOMICS (RRID:SCR_000239) Copy   

•   Source: SciCrunch Registry

https://github.com/wtsi-npg/Illuminus

A fast and accurate algorithm for assigning single nucleotide polymorphism (SNP) genotypes to microarray data from the Illumina BeadArray technology.

Proper citation: ILLUMINUS (RRID:SCR_000388) Copy   

•   Source: SciCrunch Registry

http://sourceforge.net/projects/magnolya/

A software which enables copy number variation (CNV) detections without using a reference genome. Magnolya directly compares the two next-generation sequences datasets.

Proper citation: Magnolya (RRID:SCR_000164) Copy   

•   Source: SciCrunch Registry