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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://labnodes.vanderbilt.edu/resource/view/id/10800/community_id/1418
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 6th,2023. Core whose objective is to provide investigators at Vanderbilt and outside institutions a means to accurately assess cardiovascular phenotypes in mouse models of diabetes and metabolic disease. The CPC uses validated approaches and state-of-the-art instrumentation that allow for sensitive screening of phenotypic variations.
Proper citation: MMPC-Vanderbilt University School of Medicine Cardiovascular Pathophysiology Core (RRID:SCR_015353) Copy
http://www.massgeneral.org/csibd/cores/genetic.aspx
Core whose services include breeding and maintenance of mutant mouse stocks, characterization of murine models, bone marrow transfers and adoptive T cell transfers, in vivo tracking of fluorescently labeled bacteria and cells, and whole body imaging of bioluminescent and fluorescent signals.
Proper citation: Center for the Study of Inflammatory Bowel Disease Genetic Animal Models Core (RRID:SCR_015238) Copy
http://obriencenter.yale.edu/mousecelllines.aspx
Core provides services to generate unique in vivo mouse models and kidney specific cell lines.
Proper citation: George M. O'Brien Kidney Center at Yale Mouse Genetics and Cell Line Core (RRID:SCR_015299) Copy
https://ddrcc.wustl.edu/scientific-cores/murine-models-gnotobiotics-core/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility that provides advice and technical services to DDRCC investigators that include production of transgenic and chimeric mice, derivation of speed congenics and assisted reproduction services for maintaining pedigrees via the Mouse Genetics Core, as well as gnotobiotic mouse provision, colonization and rederivation.
Proper citation: Washington University Digestive Diseases Research Core Center Murine Models and Gnotobiotics Core (RRID:SCR_015260) Copy
http://livercenter.yale.edu/core-facilities/cellular-molecular-physiology-core-facility.aspx
Core facility that provides technical expertise, equipment and personnel to Liver Center Investigators who wish to work with animal models of liver disease, isolated liver cells, or gene expression in liver tissue. The Cell Isolation sub-core isolates hepatocytes and non-parenchymal liver cells primarily from rat and mouse, while the Molecular Biology sub-core provides equipment and expertise to Liver Center members in a centralized facility.
Proper citation: Yale Liver Center Cellular and Molecular Physiology Core (RRID:SCR_015258) Copy
http://sph.unc.edu/norc/animal/
Core that offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease. It provides access to methods, equipment, and populations to support high quality and high throughput phenotyping of energy balance components in mice.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Animal Metabolism Phenotyping Core (RRID:SCR_015465) Copy
http://www.norc.uab.edu/corefacilities/animalmodels
Core that provides specialized expertise in the use of animal models and instrumentation to facilitate animal research related to nutrition and obesity.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core (RRID:SCR_015466) Copy
http://livercenter.ucsf.edu/immunology-core
Core that takes advantage of local expertise and resources to enable Center members to analyze cell populations in mouse or human livers. It performs complex analyses on small numbers of human cells, such as those obtained from liver biopsies.
Proper citation: UCSF Liver Center Immunology Core (RRID:SCR_015596) Copy
https://www.med.unc.edu/marsicolunginstitute/core-facilities/mousemodelscore
Core that provides support and expertise for mouse colony maintenance, breeding strategies, mouse lung phenotyping protocols, and submission of live-animal applications to maintain compliance with IACUC guidelines.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Mouse Models Core (RRID:SCR_015389) Copy
https://labnodes.vanderbilt.edu/resource/view/id/10822/community_id/1418
Core that ensures the health and welfare of mouse models by assuring that mice admitted to the MMPC meet defined health criteria and that post-quarantine protocol assignment. It diagnoses disease and identifies unique metabolic or cardiovascular phenotypes of mice through interaction with the Comparative Pathology Subcore.
Proper citation: MMPC-Vanderbilt University School of Medicine Animal Health and Welfare Core (RRID:SCR_015380) Copy
https://www.uab.edu/medicine/cysticfibrosis/about/animal-core
Core that assists in mouse line generation by both oocyte micro-injection and by embryonic stem cell gene targeting technologies. It also establishes breeding colonies of cystic fibrosis mice, and genotypes and provides these to UAB investigators and furnishes electrophysiology tests of CFTR activation, including murine nasal potential difference assays and intestinal short circuit current measurements.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core (RRID:SCR_015396) Copy
https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core
Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.
Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=30
Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure.
Proper citation: MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) Copy
http://www.umassmed.edu/umpc/cores/metabolism/
Core that conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic beta-cell function, body composition and energy balance. Its services include access to hyperglycemic clamps to assess insulin secretion and pancreatic beta cell function in awake mice and exercise studiesl with acute, chronic endurance, and exhaustive exercise protocols and using in-house cage wheels.
Proper citation: MMPC-University of Massachusetts Medical School Metabolism Core (RRID:SCR_015369) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=37
Core that offers measurement of gut permeability, plasma lipopolysaccharide binding protein (LBP) assay, and inflammatory profiling.
Proper citation: MMPC-University of California Davis Microbiome and Host Response Core (RRID:SCR_015361) Copy
http://www.med.upenn.edu/gtp/immunology.shtml
Core facility which provides a variety of assay services to evaluate cell-mediated and humoral responses to in animal models of gene therapies.
Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core (RRID:SCR_015409) Copy
http://www.mmpc.org/shared/showCenterCore.aspx?id=48
Core which provides a complete range of microvascular phenotyping of murine models of diabetes, obesity and metabolic disease, including validated, reproducible and standardized phenotyping of the three major microvascular complications: diabetic polyneuropathy, nephropathy and retinopathy.
Proper citation: MMPC-University of Michigan Medical School Microvascular Complications Core (RRID:SCR_015376) Copy
https://labnodes.vanderbilt.edu/resource/view/id/10810/community_id/1418
Core whose services include determining the components of energy balance with high precision and time resolution, providing robust imaging technology to monitor the dynamics of cellular process, and providing innovative mouse bariatric surgery models with application to basic and translational research.
Proper citation: MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core (RRID:SCR_015377) Copy
http://umassmed.edu/umpc/animal/humanized-mouse-core/
Core which provides humanized mice that enable clinically relevant in vivo studies of human cells, tissues, and immune system without putting patients at risk and expert in vivo functional analysis of transplanted human islets and stem cell-derived b-cells in immunodeficient mice that are highly valuable to the mouse research community.
Proper citation: MMPC-University of Massachusetts Medical School Humanized Mouse Cell Transplantation and Assessment Core (RRID:SCR_015372) Copy
http://umassmed.edu/umpc/cores/islet-core/
Core which provides comprehensive in vivo, ex vivo, and in vitro analysis of pancreatic function and islet structure. Its services include mouse pancreas preparation for histological experiments, surgical isolation of mouse islets, and islet structural analysis.
Proper citation: MMPC-University of Massachusetts Medical School Islet Core (RRID:SCR_015370) Copy
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