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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.mayo.edu/research/centers-programs/human-imaging-core/overview
Core provides semiautomated MRI and computed tomography (CT) image and volumetric analyses of polycystic kidneys and liver as well as functional assessment of the kidney and heart, including measurements of renal blood flow. It also facilitates the transmission, collection and storage of anonymized imaging data used in translational PKD research and provides a system that enables PKD researchers to exchange images.
Proper citation: Translational Polycystic Kidney Disease (PKD) Center at Mayo Clinic Rochester Human Imaging Core (RRID:SCR_015304) Copy
http://www.dukekidneycenter.org/cores/renal-genomics-core
Core facility that provides resources for investigators researching the genetic mechanisms of chronic kidney disease, cardiovascular disease, and hypertension. Its services include pre-study consultation, standardized services for DNA isolation and storage, and assisstance in carrying out molecular genetic studies.
Proper citation: Duke O'Brien Center for Kidney Research Renal Genomics Core (RRID:SCR_015269) Copy
https://ddrcc.wustl.edu/scientific-cores/murine-models-gnotobiotics-core/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 15,2026. Core facility that provides advice and technical services to DDRCC investigators that include production of transgenic and chimeric mice, derivation of speed congenics and assisted reproduction services for maintaining pedigrees via the Mouse Genetics Core, as well as gnotobiotic mouse provision, colonization and rederivation.
Proper citation: Washington University Digestive Diseases Research Core Center Murine Models and Gnotobiotics Core (RRID:SCR_015260) Copy
http://www.uab.edu/medicine/hrfdcc/cores
Core whose goals are to establish a national resource for clinical data, DNA, and tissue biopsies from human patients with HRFDs, develop algorithms to identify causative genetic mutations in HRFD patients and utilize a suite of new tools to assess the pathogenicity of sequence variants, and expand the portfolio of educational information and tools to encompass the HRFD spectrum of disorders.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Hepato-Renal Fibrocystic Diseases Translational Resource (RRID:SCR_015309) Copy
http://medicine.iupui.edu/neph/obrien/digital
Core facility which develops and implements software and methods of image segmentation for fluorescence microscopy data.
Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Digital Image Analysis Core (RRID:SCR_015276) Copy
http://www.uab.edu/medicine/hrfdcc/cores/d
Core goals include to develop in vitro predictive assays to identify and characterize HRFD lead compounds, develop in vivo predictive translational HRFD models to enhance efficacy assessment in preclinical testing, and develop advanced HRFD-specific toxicology and safety screens.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Therapeutic Screening and Drug Development Resource (RRID:SCR_015314) Copy
http://medicine.iupui.edu/neph/obrien/probe
Core facility which develops and characterizes methods for expressing fluorescent biosensors in the rodent kidney to be paried with intravital microscopy.
Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Probe Delivery Core (RRID:SCR_015274) Copy
http://www.dukekidneycenter.org/cores/clinical-and-translational-core
Core facility which investigates the connections between chronic kidney disease, cardiovascular disease, and hypertension. It focuses specifically on investigating the pathophysiology, epidemiology, and therapeutic response in on-going studies or existing datasets of one of the three diseases with the aim of relating data from individual diseases to each other.
Proper citation: Duke O'Brien Center for Kidney Research Clinical and Translational Core (RRID:SCR_015272) Copy
http://livercenter.yale.edu/core-facilities/clinical-translational-core.aspx
Core facility which aims to develop an infrastructure for patient-oriented research by streamlining regulatory and compliance processes, obtaining and storing high-quality samples linked to clinical information, offering consultation in the design and implementation of clinical trials, and supplying statistical expertise for interpreting clinical and translational data.
Proper citation: Yale Liver Center Clinical and Translational Core (RRID:SCR_015259) Copy
http://livercenter.yale.edu/core-facilities/cellular-molecular-physiology-core-facility.aspx
Core facility that provides technical expertise, equipment and personnel to Liver Center Investigators who wish to work with animal models of liver disease, isolated liver cells, or gene expression in liver tissue. The Cell Isolation sub-core isolates hepatocytes and non-parenchymal liver cells primarily from rat and mouse, while the Molecular Biology sub-core provides equipment and expertise to Liver Center members in a centralized facility.
Proper citation: Yale Liver Center Cellular and Molecular Physiology Core (RRID:SCR_015258) Copy
https://ww2.mc.vanderbilt.edu/DDRC/19909
Core facility whose services include training, acquisition and analysis on cytometers for experiments that include different fluorochromes, imaging cytometry, and mass cytometry.
Proper citation: Vanderbilt Digestive Disease Research Center Flow Cytometry Core (RRID:SCR_015251) Copy
https://ww2.mc.vanderbilt.edu/DDRC/6914
Core facility whose goals include furnishing professional guidance in experimental design and data interpretation and providing access to optical and electron microscopy. Its services include confocal microscopy, wide-field microscopy, transmission electron microscopy, and processing and embedment of tissue or cells for EM.
Proper citation: Vanderbilt Digestive Disease Research Center Cellular Imaging Core (RRID:SCR_015250) Copy
http://cihd.cores.utah.edu/mgd/
Core facility which provides custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of interest. It also provides hardware, reagents, and expertise for optimizing and performing HRMA for genes of interest.
Proper citation: Center for Iron and Heme Disorders at the University of Utah Mutation Generation and Detection Core (RRID:SCR_015339) Copy
http://animalcare.umich.edu/business-services/germ-free-mouse-facility
Core that provides services to the University of Michigan community and can also ship germ-free mice to locations worldwide. Its projects include studies investigating inflammatory bowel disease and cancer, host microbiome interactions, infectious disease pathogenesis, and mammalian and bacterial metabolism.
Proper citation: MMPC-University of Michigan Medical School Animal Care and Germ-Free Mouse Core (RRID:SCR_015344) Copy
http://sph.unc.edu/norc/animal/
Core that offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease. It provides access to methods, equipment, and populations to support high quality and high throughput phenotyping of energy balance components in mice.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Animal Metabolism Phenotyping Core (RRID:SCR_015465) Copy
http://medicine.iupui.edu/ICBM
Core facility which provides access to and training on optical microscopy instruments to Indiana University researchers.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology Optical Microscopy Core (RRID:SCR_015347) Copy
http://depts.washington.edu/uwnorc/core-facilities/energy-balance-core/
Core that provides affiliated investigators with a resource for measuring energy balance and body composition in rodent models, and for applying neuroscience techniques to nutrition and obesity-related research.
Proper citation: University of Washington Nutrition and Obesity Research Center Energy Balance Core (RRID:SCR_015469) Copy
http://www.cancer.iu.edu/research-trials/facilities/angiobiocore/index.shtml
Core facility which conducts validated and reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders.
Proper citation: Indiana University Cooperative Center of Excellence in Hematology Angiogenesis Core (RRID:SCR_015345) Copy
http://www.norc.uab.edu/corefacilities/animalmodels
Core that provides specialized expertise in the use of animal models and instrumentation to facilitate animal research related to nutrition and obesity.
Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core (RRID:SCR_015466) Copy
http://www.cancer.iu.edu/research-trials/facilities/flow-cytometry/index.shtml
Core facility which provides flow cytometry consultation, technical advice, flow cytometric analysis and cell sorting services as well as flow cytometric image analysis.
Proper citation: Indiana University School of Medicine Flow Cytometry Core Facility (RRID:SCR_015346) Copy
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