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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://samtools.sourceforge.net/tview.shtml
Text alignment viewer software based on the GNU ncurses library that works with short indels and shows MAQ consensus. It uses different colors to display mapping quality or base quality, subjected to users' choice.
Proper citation: SAMtools Text Alignment Viewer (RRID:SCR_005611) Copy
http://manatee.sourceforge.net/
Manatee is a web-based gene evaluation and genome annotation tool; Manatee can store and view annotation for prokaryotic and eukaryotic genomes. The Manatee interface allows biologists to quickly identify genes and make high quality functional assignments, such as GO classifications, using search data, paralogous families, and annotation suggestions generated from automated analysis. Manatee can be downloaded and installed to run under the CGI area of a web server, such as Apache. Platform: Online tool, Linux compatible, Solaris
Proper citation: Manatee (RRID:SCR_005685) Copy
http://sourceforge.net/projects/cancergrid-tma/
A web-based application for the management and storage of tissue microarray (TMA) images and the associated metadata. The application enables the user to navigate a grid of TMA core images within a slide, zoom and pan around an image, and enter a score constrained to a specific scoring system. The submitted scores are scored in the eXist open source database, in an XML format, which is compatible with existing TMA standards, and thus allow the data to be archived and re-used in future analysis.
Proper citation: cancergrid-tma (RRID:SCR_005595) Copy
A web-based software package for comparative genomics.
Proper citation: Sybil (RRID:SCR_005593) Copy
http://sourceforge.net/projects/dna-bison/
Allows users with access to a computer cluster to rapidly align whole-genome bisulfite sequencing or RRBS reads.
Proper citation: dna-bison (RRID:SCR_005913) Copy
http://dti-tk.sourceforge.net/pmwiki/pmwiki.php
A spatial normalization and atlas construction toolkit optimized for examining white matter morphometry using DTI data with special care taken to respect the tensorial nature of the data. It implements a state-of-the-art registration algorithm that drives the alignment of white matter (WM) tracts by matching the orientation of the underlying fiber bundle at each voxel. The algorithm has been shown to both improve WM tract alignment and to enhance the power of statistical inference in clinical settings. A 2011 study published in NeuroImage ranks DTI-TK the top-performing tool in its class. Key features include: * open standard-based file IO support: NIfTI format for scalar, vector and tensor image volumes * tool chains for manipulating tensor image volumes: resampling, smoothing, warping, registration & visualization * pipelines for WM morphometry: spatial normalization & atlas construction for population-based studies * built-in cluster-computing support: support for open source Sun Grid Engine (SGE) * Interoperability with other popular DTI tools: AFNI, Camino, FSL & DTIStudio * Interoperability with ITK-SNAP: support multi-modal visualization and segmentation
Proper citation: Diffusion Tensor Imaging ToolKit (RRID:SCR_001642) Copy
http://sourceforge.net/projects/pennseq/
Software for isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution. Instead of making parametric assumptions, they give adequate weight to the underlying data by the use of a non-parametric approach. The rationale is that regardless what factors lead to non-uniformity, whether it is due to hexamer priming bias, local sequence bias, positional bias, RNA degradation, mapping bias or other unknown reasons, the probability that a fragment is sampled from a particular region will be reflected in the aligned data. This empirical approach thus maximally reflects the true underlying non-uniform read distribution.
Proper citation: PennSeq (RRID:SCR_001763) Copy
http://sourceforge.net/projects/denovoassembler/files/
Software that assembles reads obtained with new sequencing technologies (Illumina, 454, SOLiD) using MPI 2.2.
Proper citation: Ray (RRID:SCR_001916) Copy
http://sourceforge.net/projects/openadam/
A web-based database management system for the large amount of genotype data generated from the Affymetrix GeneChip Mapping Array and Genome-Wide Human SNP Array platforms.
Proper citation: openADAM (RRID:SCR_002018) Copy
http://sourceforge.net/projects/dmetanalyzer/
Software tool for the automatic association analysis among the variation of the patient genomes and the clinical conditions of patients, i.e. the different response to drugs. The system allows: (i) to automatize the workflow of analysis of DMET (drug metabolism enzymes and transporters)-SNP (Single Nucleotide Polymorphism) data avoiding the use of multiple tools; (ii) the automatic annotation of DMET-SNP data and the search in existing databases of SNPs (e.g. dbSNP), (iii) the association of SNP with pathway through the search in PharmaKGB, a major knowledge base for pharmacogenomic studies. It has a simple graphical user interface that allows users (doctors/biologists) to upload and analyze DMET files produced by Affymetrix DMET-Console in an interactive way.
Proper citation: DMET-Analyzer (RRID:SCR_002030) Copy
Statistical software tool for calling common and rare variants in analysis of pool or individual next-generation sequencing data. This software is optimized for analysis of whole-exome sequencing data and whole-genome sequencing data.
Proper citation: SNVer (RRID:SCR_002061) Copy
http://sourceforge.net/projects/cgap-align/
A time efficient read alignment tool built on the top of BWA.
Proper citation: CGAP-Align (RRID:SCR_000350) Copy
http://cutenmr.sourceforge.net/
A multi-platform NMR processing application.
Proper citation: cuteNMR (RRID:SCR_000347) Copy
http://sourceforge.net/projects/jmoldraw/
2-D chemical structure drawing software program.
Proper citation: JMolDraw (RRID:SCR_000349) Copy
http://sourceforge.net/projects/as-peak/
A software that utilizes a peak detection algorithm to identify RNA-protein binding sites.
Proper citation: AS-Peak (RRID:SCR_000380) Copy
http://sourceforge.net/projects/genseng/
Software for detecting copy number variations from next generation sequencing data. Used to identify regions of discrete copy number changes while simultaneously accounting for effects of multiple confounders.
Proper citation: GENSENG (RRID:SCR_000378) Copy
http://sourceforge.net/projects/arrayplex/
Open source software that integrates various forms of microarray data from diverse annotation and primary data sources. This software provides a programmatic framework (API set) that will be used for collaborative development and deploys an easy to maintain client-server architecture.
Proper citation: ArrayPlex (RRID:SCR_000312) Copy
http://sourceforge.net/projects/microanalyzer/
Java tool that performs the preprocessing of Expression and SNPs microarray Affymetrix. The software allows the automatic download and the use of the clustering and visualization software as the Mev 4.0. The tool is equipped by a graphical interface (Swing) that allows to the user to: Create the workspace (files .cel, preferred algorithms , output, libraries to use); Run/save analysis and workspace settings (xml); Efficient download of the libraries (http, ftp, MD5); Customize basic and graphical settings (objects serialization and deserialization). Type of SNPs: Mapping 500k or preceding chips, SNP 5.0, SNP 6.0. Available for 32 or 64 bit systems, and for Windows and Linux Systems.
Proper citation: Micro-Analyzer (RRID:SCR_000394) Copy
http://functsnp.sourceforge.net/
An R package for linking SNPs (Single Nucleotide Polymorphisms) to functional knowledge.
Proper citation: FunctSNP (RRID:SCR_000393) Copy
http://sourceforge.net/projects/limsforproteomi/
Laboratory information management system for proteomics. The software works with 2DPAGE-based proteomics workflow.
Proper citation: LIPAGE (RRID:SCR_000290) Copy
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