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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.qd-taiwan.com/siteDocs/productBrochures/NanoTemper_NT115_series.pdf
Instrument used to quantify biomolecular interactions and measure their binding affinity using MicroScale Thermophoresis. Can determine the strength of binding between all types of biomolecules, from single ions to large complexes, in various complex samples and buffer conditions.
Proper citation: NanoTemper: Monolith NT.115 (RRID:SCR_027500) Copy
Concordia University is a public English-language research university located in Montreal, Quebec, Canada. Founded in 1974 following the merger of Loyola College and Sir George Williams University, Concordia is one of the three universities in Quebec where English is the primary language of instruction.
Proper citation: Concordia University; Montreal; Canada (RRID:SCR_027512) Copy
Microscope patented optics are setting new standards in modular common main objective stereomicroscopy. Thanks to higher resolution and significantly increased contrast, they provide 20% more image information – in addition to 3D images. The innovative operating concept SyCoP (Systems Control Panel) combines all essential functions of stereomicroscope in single handy operating unit. Used particularly for applications in materials research, quality control, biology and medical research.
Proper citation: Zeiss: SteREO Discovery.V12 (RRID:SCR_027509) Copy
https://www.dnagenotek.com/row/index
Subsidiary of OraSure Technologies, Inc. focuses on providing biological sample collection products and services for human genomics, microbiome and infectious disease applications. Offers Research Use Only products to collect and preserve large amounts of DNA or RNA from multiple sample types.
Proper citation: DNA Genotek Inc (RRID:SCR_027611) Copy
https://atlantis.bioinfolab.sns.it
Integrative database for human proteome structural and functional sites. Used for understanding role of specific residues in protein structures, complexes, and interaction networks. Integrates various structural and functional annotation layers for each residue, offering comprehensive understanding of protein functionality.
Proper citation: Atlantis (RRID:SCR_027648) Copy
Data platform providing centralized and secure access to rich, longitudinal brain, behavioral, and genomic data from both the Adolescent Brain Cognitive Development (ABCD) and the HEALthy Brain and Child Development (HBCD) Studies. By bringing together data from both studies, the NBDC Data Hub facilitates integrative research on early life and adolescent development, helping researchers explore developmental trajectories across the lifespan.
Proper citation: NIH Brain Development Cohorts (NBDC) Data Hub (RRID:SCR_027710) Copy
https://smirnovgroup.wordpress.ncsu.edu/e580-a-shared-x-q-band-instrument/
Bruker ELEXSYS-E580 pulse X-/Q-band instrument offers state-of-the-art capabilities for both standard and cutting-edge EPR spectroscopy across a broad range of sample types and experimental needs. High-performance Electron Paramagnetic Resonance (EPR) spectrometer used for advanced research in chemistry, materials science, biochemistry, and physics, enabling studies of paramagnetic molecules, protein structures, quantum states, and materials by combining X-band (9-10 GHz) and Q-band (34 GHz) frequencies for high-resolution, sensitive pulse techniques.
Proper citation: Bruker: ELEXSYS-E580 pulse X-/Q-band system (RRID:SCR_027754) Copy
http://bionlp.bcgsc.ca/cancermine/
Text-mined and routinely updated database of drivers, oncogenes and tumor suppressors in different types of cancer.
Proper citation: CancerMine (RRID:SCR_027748) Copy
World-renowned institution dedicated to ending cancer through expert, compassionate patient care, pioneering research, and education for adults and children with all types of cancer, combining cutting-edge science with a holistic approach to treatment and support. Its mission focuses on innovative diagnosis and treatment (surgery, chemo, radiation, immunotherapy), supportive care (nursing, counseling, rehab), and training future cancer leaders.
Proper citation: Memorial Sloan Kettering Cancer Center (RRID:SCR_027785) Copy
Interactive database and user interface providing online access to validated alternative methods for U.S. regulatory and other contexts of use. Central hub and unified resource of validated alternative methods that enhances accessibility to validation study reports, data, protocols / SOPs, and information on regulatory guidance.Users can filter searches by alternative method types, defined approaches, Test Method Endpoint, and regulatory guidance.
Proper citation: Collection of Alternative Methods for Regulatory Application (CAMERA) (RRID:SCR_027893) Copy
Mid-volume, automated immunoassay system used in clinical labs to perform a wide range of tests for diagnosing and monitoring diseases, detecting infections, checking hormone levels, and assessing cardiac health, by analyzing biological samples like blood for specific proteins, hormones, and other markers with high reliability and efficiency, often integrated into the larger, flexible Atellica Solution for automated workflows.
Proper citation: Siemens: Atellica IM 1300 Analyzer (RRID:SCR_027876) Copy
Centralized, annotated repository for the Osteoarthritis Initiative (OAI) study, designed to accelerate research by organizing and linking extensive clinical, imaging (MRI/X-ray), and biomarker data. It aims to help researchers analyze knee osteoarthritis prevention, treatment, and progression.
Proper citation: OAI Knowledge base (RRID:SCR_028107) Copy
http://amp.pharm.mssm.edu/Enrichr/
A web-based gene list enrichment analysis tool that provides various types of visualization summaries of collective functions of gene lists. It includes new gene-set libraries, an alternative approach to rank enriched terms, and various interactive visualization approaches to display enrichment results using the JavaScript library, Data Driven Documents (D3). The software can also be embedded into any tool that performs gene list analysis. System-wide profiling of genes and proteins in mammalian cells produce lists of differentially expressed genes / proteins that need to be further analyzed for their collective functions in order to extract new knowledge. Once unbiased lists of genes or proteins are generated from such experiments, these lists are used as input for computing enrichment with existing lists created from prior knowledge organized into gene-set libraries.
Proper citation: Enrichr (RRID:SCR_001575) Copy
http://neuroinformatics.kiv.zcu.cz/articles/read/eegerp-portal-eegbase-_2014-12-19
EEG base is a system for storage and management of EEG/ERP resources - data, metadata, tools and materials related to EEG/ERP experiments. EEG base advances electrophysiology research by enabling access to public data, tools and results of research groups. The system essentially offers the following set of features (the set of accessible features depends on a specific user role): * User authentication * Storage, update, and download of EEG/ERP data and metadata * Storage, update and download of EEG/ERP experimental design (experimental scenarios) * Storage, update and download of data related to testing subjects * Fulltext search * Sharing of knowledge and working in groups The system is based on tree layer architecture (MVC pattern) consisting of persistent layer (relational database), application layer (object oriented code, object relational mapping from persistence layer) and presentation layer (JSP). The persistence layer uses Hibernate framework; Oracle 11g database server is used to ensure the processing of large data files. Application and presentation layers are designed and implemented using Spring technology. This framework supports MVC architecture, Dependency injection and Aspect Oriented Programming. There were no significant difficulties with integration of both frameworks, Hibernate and Spring MVC. Spring Security framework is used to ensure management of authentication and user roles. Since the system is thought to be finally open to the whole EEG/ERP community it is necessary to protect EEG/ERP data and metadata, and especially personal data of testing subjects stored in the database from an unauthorized access. Then a restricted user policy is applied and user roles are introduced. The complete overview of the system features and user roles (use case diagram) is available in (Pergler 2009). Concerning the architectural layers there is a question which layer is more feasible for mapping of its structure into ontology. Currently we have studied two possibilities: * Mapping from the persistence layer (relational database) * Mapping from the application layer (object oriented code) The mapping from the application layer to an ontology includes the precedent object relational mapping provided by Hibernate framework.
Proper citation: EEGbase (RRID:SCR_001452) Copy
http://www.glycosciences.de/tools/glytorsion/
Service that performs a statistical analysis of carbohydrate torsion angles derived from the Protein Data Bank. Such as protein conformation can be described by the backbone torsion angles, a carbohydrate structure is mainly characterised by its linkage torsions. With the aid of pdb2linucs, a dataset of carbohydrate torsion angles was derived from from carbohydrate structures found in the PDB. This weekly updated dataset contains, besides linkage torsions, also ring torsions, omega torsions, N-acetyle group torsions and sidechain torsions of Asn residues involved in Glycan bonds. It can be queried by GlyTorsion.
Proper citation: GlyTorsion (RRID:SCR_001568) Copy
http://www.glycosciences.de/tools/glyseq/
Service dedicated to statistically analyze the sequences around glycosylation sites. Glycosylation belongs to the most common and most important co- and postranslational modifications of proteins. Since it is often difficult to determine which potential glycosylation sites are in fact glycosylated, there is only few data available about glycoproteins. Sources from which such data can be retrieved are SwissProt and the Protein Data Bank (PDB). Data from the PDB is obtained using pdb2linucs and updated weekly. GlySeq is dedicated to statistically analyze these sequences, especially the areas around glycosylation sites.
Proper citation: GlySeq (RRID:SCR_001569) Copy
Biomedical technology research center that creates optimal facilities and environments and support for macromolecular structure determination by synchrotron X-ray diffraction at the National Synchrotron Light Source for the benefit of outside and in-house investigators. The PXRR innovates new access modes such as Mail-in crystallography, builds new facilities, currently on the X25 undulator, advances automation, develops remote participation software, collaborates with outside groups, teaches novice users, and supports vising investigators with 7-day, 20-hours staff coverage.
Proper citation: Macromolecular Crystallography Research Resource (RRID:SCR_001442) Copy
https://medicine.yale.edu/keck/nida/yped/
Open source system for storage, retrieval, and integrated analysis of large amounts of data from high throughput proteomic technologies. YPED currently handles LCMS, MudPIT, ICAT, iTRAQ, SILAC, 2D Gel and DIGE. The repository contains data sets which have been released for public viewing and downloading by the responsible Primary Investigators. It includes proteomic data generated by the Yale NIDA Neuroproteomics Center (http://medicine.yale.edu/keck/nida/index.aspx). Sample descriptions are compatible with the evolving MIAPE standards.
Proper citation: YPED (RRID:SCR_001436) Copy
https://repository.niddk.nih.gov/study/21
Data and biological samples were collected by this consortium organizing international efforts to identify genes that determine an individual risk of type 1 diabetes. It originally focused on recruiting families with at least two siblings (brothers and/or sisters) who have type 1 diabetes (affected sibling pair or ASP families). The T1DGC completed enrollment for these families in August 2009. They completed enrollment of trios (father, mother, and a child with type 1 diabetes), as well as cases (people with type 1 diabetes) and controls (people with no history of type 1 diabetes) from populations with a low prevalence of this disease in January 2010. T1DGC Data and Samples: Phenotypic and genotypic data as well as biological samples (DNA, serum and plasma) for T1DGC participants have been deposited in the NIDDKCentral Repositories for future research.
Proper citation: Type 1 Diabetes Genetics Consortium (RRID:SCR_001557) Copy
http://www.anxietyaustralia.com.au/
Anxiety Treatment Australia provides information about anxiety disorders, the treatment options, psychologists around Australia who treat anxiety disorders, group therapy & workshops, support groups, articles, resources and links to other sites. Sponsors: his website is brought to you by Catherine Madigan, a Melbourne Clinical Psychologist who specializes in the treatment of Anxiety Disorders (ABN 51 109 368 630).
Proper citation: Anxiety Treatment Australia: Anxiety Disorder Help, Information and Psychologist List (RRID:SCR_001434) Copy
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