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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SkateBase
 
Resource Report
Resource Website
10+ mentions
SkateBase (RRID:SCR_005302) SkateBase data analysis service, analysis service resource, production service resource, service resource, database, data or information resource Portal supporting the North East Bioinformatics Collaborative''s project to sequence the genome of the Little Skate. Provided is a clearinghouse for Little Skate Genome Project and other publicly available Skate and Ray (Batoidea) genome data, and tools for data visualization and analysis. Little Skate Genome Project The little skate (Leucoraja erinacea) is a chondrichthyan (cartilaginous) fish native to the east coast of North America. Elasmobranchs (Skates, Rays, and Sharks) exhibit many fundamental vertebrate characteristics, including a neural crest, jaws and teeth, an adaptive immune system, and a pressurized circulatory system. These characteristics have been exploited to promote understanding about human physiology, immunology, stem cell biology, toxicology, neurobiology and regeneration. The development of standardized experimental protocols in elasmobranchs such as L. erinacea and the spiny dogfish shark (Squalus acanthias) has further positioned these organisms as important biomedical and developmental models. Despite this distinction, the only reported chondrichthyan genome is the low coverage (1.4x) draft genome of the elephant shark (Callorhinchus milii). To close the evolutionary gaps in available elasmobranch genome sequence data, and generate critical genomic resources for future biomedical study, the genome of L. erinacea is being sequenced by the North East Bioinformatics Collaborative (NEBC). As close evolutionary relatives, the little skate sequence will facilitate studies that employ dogfish shark and other elasmobranchs as model organisms. Skate tools include the SkateBLAST and the Skate Genome Browsers: Little Skate Mitochondrion, Thorny Skate Mitochondrion, and Ocellate Spot Skate Mitochondrion. little skate, leucoraja erinacea, sequence, genome, mitochondrion, thorny skate, ocellate spot skate, FASEB list has parent organization: North East Cyberinfrastructure Consortium
has parent organization: University of Delaware; Delaware; USA
has parent organization: University of Delaware Skate Genome Project
NIGMS 3P20GM103446-12S1 nlx_144350 SCR_005302 2026-08-04 09:41:20 40
TOPSAN
 
Resource Report
Resource Website
10+ mentions
TOPSAN (RRID:SCR_005758) TOPSAN image collection, storage service resource, data repository, service resource, database, data or information resource Collect, share, and distribute information about protein three-dimensional structures. It serves as a portal for the scientific community to learn about protein structures solved by SG centers, and also to contribute their expertise in annotating protein function. The premise of the TOPSAN project is that, no matter how much any individual knows about a particular protein, there are other members of the scientific community who know more about certain aspects of the same protein, and that the collective analyses from experts will be far more informative than any local group, let alone individual, could contribute. They believe that, if the members of the biological community are given the opportunity, authorship incentives, and an easy way to contribute their knowledge to the structure annotation, they would do so. Therefore, borrowing elements from successful, distributed, collaborative projects, such as Wikipedia (the free encyclopedia anyone can edit) and from other open source software development projects, TOPSAN will be a broad, collaborative effort to annotate protein structures, initially, those determined at the JCSG. They believe that the annotation of proteins solved by structural genomics consortia offers a unique opportunity to challenge the extant paradigm of how biological data is collected and distributed, and to connect structural genomics and structural biology to the entire biological research community. TOPSAN is designed to be scalable, modular and extensible. Furthermore, it is intended to be immediately useful in a simplistic way and will accommodate incremental improvements to functionality as usage becomes more sophisticated. Their annotation pages will offer the end user a combination of automatically generated as well as expert-curated annotations of protein structures. They will use available technology to increase the speed and granularity of the exchange of scientific ideas, and use incentive mechanisms that will encourage collaborative participation. protein, structure, 3d, protein structure, protein function, annotate, crowd sourcing, image, annotation, genomics, collaboration has parent organization: Sanford Burnham Prebys Medical Discovery Institute
has parent organization: University of California at San Diego; California; USA
NIGMS U54 GM074898;
NIGMS P20 GM076221
PMID:20961957
PMID:20716366
PMID:20944203
PMID:20961957
Creative Commons Attribution v3 License, The community can contribute to this resource nlx_149221 SCR_005758 he Open Protein Structure Annotation Network, TOPSAN Project, TOPSAN - The Open Protein Structure Annotation Network 2026-08-04 09:41:26 10
NIGMS Multimedia
 
Resource Report
Resource Website
NIGMS Multimedia (RRID:SCR_005712) NIGMS Multimedia podcast, narrative resource, data or information resource, video resource As part of its multimedia outreach, the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health -- the United States'' medical research agency -- offers audio and video podcasts and other multimedia resources that explore the exciting world of basic biomedical research. basic research, biomedical research, biomedical has parent organization: National Institute of General Medical Sciences NIGMS nlx_149379 SCR_005712 NIGMS Media Gallery, NIGMS - Multimedia, NIGMS - Media Gallery 2026-08-04 09:41:25 0
ChemHealthWeb
 
Resource Report
Resource Website
ChemHealthWeb (RRID:SCR_005851) ChemHealthWeb portal, video resource, topical portal, training material, narrative resource, data or information resource Visit ChemHealthWeb for research highlights, chemist profiles, games and videos and other Web extras. The NIGMS Chemistry of Health booklet describes basic chemistry and biochemistry research that spurs a better understanding of human health. chemistry, health, chemistry, biochemistry, research, human, game, puzzle, chemist, molecule, medicine, teacher has parent organization: National Institute of General Medical Sciences NIGMS nlx_149382 SCR_005851 2026-08-04 09:41:28 0
Polbase
 
Resource Report
Resource Website
Polbase (RRID:SCR_006107) storage service resource, data repository, service resource, database, data or information resource Repository of biochemical, genetic, and structural information about DNA Polymerases. Polbase is designed to compile detailed results of polymerase experimentation, presenting them in a dynamic view to inform further research. After validation, results from references are displayed in context with relevant experimental details and are always traceable to their source publication. Polbase is connected to other resources, including PubMed, UniProt and the RCSB Protein Data Bank, to provide multi-faceted views of polymerase knowledge. In addition to a simple web interface, Polbase data is exposed for custom analysis by external software. dna polymerase repository, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: PubMed
is related to: UniProt
has parent organization: New England Biolabs
Small Business Innovation Research ;
NIGMS 1R44GM087021
PMID:21993301 Free, Open unspecified license, Acknowledgement required biotools:polbase, nlx_151580 https://bio.tools/polbase SCR_006107 DNA Polymerase Database 2026-08-04 09:41:31 0
Simtk.org
 
Resource Report
Resource Website
10+ mentions
Simtk.org (RRID:SCR_002680) SimTK simulation software, software application, software resource, software repository A National NIH Center for Biomedical Computing that focuses on physics-based simulation of biological structures and provides open access to high quality simulation tools, accurate models and the people behind them. It serves as a repository for models that are published (as well as the associated code) to create a living archive of simulation scholarship. Simtk.org is organized into projects. A project represents a research endeavor, a software package or a collection of documents and publications. Includes sharing of image files, media, references to publications and manuscripts, as well as executables and applications for download and source code. Simulation tools are free to download and space is available for developers to manage, share and disseminate code. model, modeling, rna folding, protein folding, myosin dynamics, neuromuscular biomechanics, cardiovascular dynamics, biomolecular simulation, biomedical computing, repository, cardiovascular, neuromuscular, myosin, rna, simulation, biocomputation is used by: NIF Data Federation
lists: Adaptively Sampled Particle Fluids
lists: OpenMM
lists: CPODES numerical integrator
is listed by: Biositemaps
is listed by: Integrated Models
is listed by: DataCite
is listed by: re3data.org
is related to: OpenSim
is related to: Simbody(tm): SimTK Multibody Dynamics Toolset
is related to: SimVascular
is related to: SAFA Footprinting Software
is related to: Ion Simulator Interface
is related to: LAPACK linear algebra library
is related to: Neuromuscular Models Library
has parent organization: Simbios
is parent organization of: FEATURE
is parent organization of: Cardiovascular Model Repository
is parent organization of: ConTrack
is parent organization of: Allopathfinder
is parent organization of: Molecular Simulation Trajectories Archive of a Villin Variant
is parent organization of: LAPACK linear algebra library
is parent organization of: SimTKCore
NIH ;
NIGMS U54 GM072970
Free, Available for download, Freely available nif-0000-23302, DOI:10.17616/R3QJ4B, DOI:10.18735 https://doi.org/10.17616/R3QJ4B, https://doi.org/10.17616/r3qj4b, https://doi.org/10.18735/, https://dx.doi.org/10.18735/ SCR_002680 Simulation Toolkit, SimTK - the Simulation Toolkit 2026-08-04 09:40:42 18
BioPortal
 
Resource Report
Resource Website
100+ mentions
BioPortal (RRID:SCR_002713) BioPortal repository, storage service resource, controlled vocabulary, data repository, service resource, ontology, data or information resource Open repository of biomedical ontologies that provides access via Web browsers and Web services to ontologies. It supports ontologies in OBO format, OWL, RDF, Rich Release Format (RRF), Protege frames, and LexGrid XML. Functionality includes the ability to browse, search and visualize ontologies as well as to comment on, and create mappings for ontologies. Any registered user can submit an ontology. The NCBO Annotator and NCBO Resource Index can also be accessed via BioPortal. Additional features: * Add Reviews: rate the ontology according to several criteria and describe your experience using the ontology. * Add Mappings: submit point-to-point mappings or upload bulk mappings created with external tools. Notification of new Mappings is RSS-enabled and Mappings can be browsed via BioPortal and accessed via Web services. * NCBO Annotator: Tool that tags free text with ontology terms. NCBO uses the Annotator to generate ontology annotations, creating an ontology index of these resources accessible via the NCBO Resource Index. The Annotator can be accessed through BioPortal or directly as a Web service. The annotation workflow is based on syntactic concept recognition (using the preferred name and synonyms for terms) and on a set of semantic expansion algorithms that leverage the ontology structure (e.g., is_a relations). * NCBO Resource Index: The NCBO Resource Index is a system for ontology based annotation and indexing of biomedical data; the key functionality of this system is to enable users to locate biomedical data linked via ontology terms. A set of annotations is generated automatically, using the NCBO Annotator, and presented in BioPortal. This service uses a concept recognizer (developed by the National Center for Integrative Biomedical Informatics, University of Michigan) to produce a set of annotations and expand them using ontology is_a relations. * Web services: Documentation on all Web services and example code is available at: BioPortal Web services. biomedical, thesaurus, ontology mapping, annotation, metadata standard, ontology repository, portal, web service, obo, owl, rdf, rrf protege frame, lexgrid xml lists: MeGO
lists: Porifera Ontology
lists: EnvO
lists: Research Network and Patient Registry Inventory Ontology
lists: Semantic DICOM Ontology
lists: Time Event Ontology
lists: Variation Ontology
lists: Vertebrate Skeletal Anatomy Ontology
lists: Epoch Clinical Trial Ontology
lists: Gazetteer
lists: Human Disease Ontology
lists: Information Artifact Ontology
lists: NCBITaxon
lists: Amphibian Taxonomy Ontology
lists: Anatomic Pathology Lexicon
lists: HIV ontology
lists: International Classification of Primary Care - 2 PLUS
lists: Mathematical Modelling Ontology
lists: Nursing Interventions Classification
lists: Phylogenetic Ontology
lists: Bleeding History Phenotype Ontology
lists: Body System Terms from ICD11
lists: Synthetic Biology Open Language Visual Ontology
lists: Teleost Anatomy Ontology
lists: Teleost Taxonomy Ontology
lists: ECO
lists: Bioassay Ontology
lists: RightField
lists: Gene Ontology
lists: HGNC
lists: Interaction Ontology
lists: International Classification for Nursing Practice
lists: Spider Ontology
lists: Vertebrate Trait Ontology
lists: Mental Functioning Ontology
lists: Ascomycete Phenotype Ontology
lists: Beta Cell Genomics Ontology
lists: Biological Collections Ontology
lists: Chemical Methods Ontology
lists: Chemical Information Ontology
lists: Common Anatomy Reference Ontology
lists: Experimental Conditions Ontology
lists: Dictyostelium Discoideum Anatomy Ontology
lists: Fission Yeast Phenotype Ontology
lists: Fly Taxonomy
lists: FlyBase Controlled Vocabulary
lists: Hymenoptera Anatomy Ontology
lists: Influenza Ontology
lists: Lipid Ontology
lists: Kinetic Simulation Algorithm Ontology
lists: Malaria Ontology
lists: FMA
lists: Minimal Anatomical Terminology
lists: NEMO Ontology
lists: Ontology for Genetic Interval
lists: Ontology for Parasite LifeCycle
lists: Ontology of Adverse Events
lists: Ontology of Medically Related Social Entities
lists: Ontology of Vaccine Adverse Events
lists: Rat Strain Ontology
lists: Plant Environmental Conditions
lists: Plant Trait Ontology
lists: Population and Community Ontology
lists: RNA Ontology
lists: Rat Strain Ontology
lists: Subcellular Anatomy Ontology
lists: Software Ontology
lists: Suggested Ontology for Pharmacogenomics
lists: Vertebrate Taxonomy Ontology
lists: PharmGKB Ontology
lists: Physico-Chemical Process
lists: International Classification for Patient Safety
lists: Adverse Event Reporting Ontology
lists: Experimental Factor Ontology
lists: Mass Spectrometry Ontology
lists: Master Drug Data Base Clinical Drugs
lists: Medaka Fish Anatomy and Development Ontology
lists: Medical Diagnostic Categories - Diagnosis Related Groups
lists: Medical Dictionary for Regulatory Activities
lists: Minimal Standard Terminology of Digestive Endoscopy
lists: Minimal Standard Terminology of Digestive Endoscopy - French
lists: Ontology of Physical Exercises
lists: Mosquito Gross Anatomy Ontology
lists: Systematized Nomenclature of Medicine - International Version
lists: Mosquito Insecticide Resistance Ontology
lists: Mouse Experimental Design Ontology
lists: Mouse Gross Anatomy and Development Ontology
lists: Systematized Nomenclature of Medicine - Clinical Terms
lists: Systems Chemical Biology and Chemogenomics Ontology
lists: Mouse Pathology Ontology
lists: NIF Cell Ontology
lists: NHS Quality Indicators
lists: Neural-Immune Gene Ontology
lists: Ontology of Physics for Biology
lists: Cell Type Ontology
lists: Xenopus Anatomy Ontology
lists: SO
lists: Ontology of Pneumology
lists: Open Biological and Biomedical Ontologies Relationship Types
lists: Biomedical Resource Ontology
lists: MGED Ontology
lists: Pharmacovigilance Ontology
lists: PhenX Phenotypic Terms
lists: Bioinformatics Web Service Ontology
lists: SysMO JERM Ontology of Systems Biology for Micro-Organisms
lists: MeSH
lists: PATO
lists: BFO
lists: MPO
lists: PR
lists: Cereal Plant Development Ontology
lists: PhenomeBLAST Ontology
lists: VIVO
lists: Computer Assisted Brain Injury Rehabilitation Ontology
lists: Computer Retrieval of Information on Scientific Projects Thesaurus
lists: NIFSTD
lists: Cell Line Ontology
lists: Student Health Record Ontology
lists: Zebrafish Anatomical Ontology
lists: Physical Medicine and Rehabilitation
lists: Randomized Controlled Trials Ontology
lists: Human Phenotype Ontology
lists: Read Codes Clinical Terms Version 3
lists: Reference Sequence Annotation
lists: Regulation of Gene Expression Ontolology
lists: Neurobehavior Ontology
lists: Regulation of Transcription Ontology
lists: Reproductive Trait and Phenotype Ontology
lists: Skin Physiology Ontology
lists: Vaccine Ontology
lists: OMIM
lists: MedlinePlus
lists: Adult Mouse Anatomy Ontology
lists: Bone Dysplasia Ontology
lists: Bone and Cartilage Tissue Engineering Ontology
lists: Botryllus schlosseri anatomy and development ontology
lists: EDAM Ontology
lists: LexGrid
lists: RxNorm
lists: Breast Cancer Grading Ontology
lists: Breast Tissue Cell Lines Ontology
lists: SBO
lists: Resource of Asian Primary Immunodeficiency Diseases Phenotype Ontology
lists: Brucellosis Ontology
lists: Sleep Domain Ontology
lists: C. elegans Development Vocabulary
lists: Physician Data Query
lists: C. elegans Gross Anatomy Vocabulary
lists: Plant Ontology
lists: C. elegans Phenotype Vocabulary
lists: CPTAC Proteomics Pipeline Infrastructure Ontology
lists: Cancer Research and Management ACGT Master Ontology
lists: Cancer Chemoprevention Ontology
lists: Cell Behavior Ontology
lists: Cereal Plant Gross Anatomy Ontology
lists: Cardiac Electrophysiology Ontology
lists: Cerebrotendinous Xanthomatosis Ontology
lists: Cell Cycle Ontology
lists: Cell Culture Ontology
lists: Cerrado concepts and plant community dynamics
lists: Clinical Signs and Symptoms Ontology
lists: Clusters of Orthologous Groups Analysis Ontology
lists: Computational Neuroscience Ontology
lists: BIRNLex
lists: Computer-Based Patient Record Ontology
lists: Congenital Heart Defects Ontology
lists: Drug Interaction Knowledge Base Ontology
lists: Healthcare Common Procedure Coding System
lists: Host Pathogen Interactions Ontology
lists: Human Dermatological Disease Ontology
lists: Solanaceae Phenotype Ontology
lists: Soy Ontology
lists: Spatial Ontology
lists: Surgical Secondary Events
lists: eagle-i research resource ontology
lists: Biological Pathways Exchange
lists: Autism Spectrum Disorder Phenotype Ontology
lists: BRENDA Tissue and Enzyme Source Ontology
lists: BioTop Ontology
lists: Family Health History Ontology
lists: International Classification of Diseases Version 9 - Clinical Modification
lists: BioModels Ontology
lists: Bilingual Ontology of Alzheimer
lists: BioPortal Metadata Ontology
lists: Biochemical Substructure Ontology
lists: Biodiversity Ontology
lists: Biological Imaging Methods Ontology
lists: International Classification of Functioning Disability and Health
lists: Biologie Hors Nomenclature
lists: International Classification of Primary Care
lists: Biomedical Research Integrated Domain Group Model
lists: KB Bio 101
lists: Bionutrition Ontology
lists: Artificial Intelligence Rheumatology Consultant System Ontology
lists: Leukocyte Surface Marker Ontology
lists: Cell Line Ontology by Mahadevan
lists: Cellular microscopy phenotype ontology
lists: ABA Adult Mouse Brain Ontology
lists: AEO
lists: African Traditional Medicine Ontology
lists: Alzheimer's disease ontology
lists: Amino Acid Ontology
lists: Amphibian Gross Anatomy Ontology
lists: Animal Natural History and Life History Ontology
lists: Coding Symbols for a Thesaurus of Adverse Reaction Terms
lists: Cognitive Atlas Ontology
lists: Common Terminology Criteria for Adverse Events
lists: Comparative Data Analysis Ontology
lists: Content Archive Resource Exchange Lexicon
lists: Crop Ontology
lists: Current Procedural Terminalogy Hierarchy
lists: Current Procedural Terminology
lists: DICOM Controlled Terminology
lists: Dataset processing
lists: Dengue Fever Ontology
lists: Dermatology Lexicon
lists: Diagnosis Ontology of Clinical Care Classification
lists: Diagnostic Ontology
lists: Disease core ontology applied to Rare Diseases
lists: Dispedia Core Ontology
lists: Drosophila Development Ontology
lists: Drosophila Gross Anatomy Ontology
lists: EDDA Study Design Terminology
lists: Electrocardiography Ontology
lists: Eligibility Feature Hierarchy
lists: Enzyme Mechanism Ontology
lists: Enzyme Reaction Ontology for partial chemical perspectives
lists: Epilepsy Ontology
lists: Loggerhead Nesting Ontology
lists: Fanconi Anemia Ontology
lists: Fire Ontology
lists: Flora Phenotype Ontology
lists: Fungal Gross Anatomy Ontology
lists: Human Developmental Anatomy Ontology abstract version 1
lists: G Protein-Coupled Receptor BioAssays Ontology
lists: Galen Ontology
lists: Gene Expression Ontology
lists: Gene Ontology Extension
lists: General Formal Ontology
lists: General Formal Ontology for Biology
lists: Genome Component Ontology
lists: Genomic Clinical Decision Support Ontology
lists: GeoSpecies Ontology
lists: Glycomics Ontology
lists: Habronattus Courtship Ontology
lists: Health Indicator Ontology
lists: Health Level Seven Reference Implementation Model Version 3
lists: Human Developmental Anatomy Ontology abstract version 2
lists: Human Developmental Anatomy Ontology timed version
lists: Human Interaction Network Ontology
lists: Human Physiology Simulation Ontology
lists: Logical Observation Identifier Names and Codes
lists: IMGT-ONTOLOGY
lists: Image and Data Quality Assessment Ontology
lists: Immune Disorder Ontology
lists: Infectious Disease Ontology
lists: InterNano Nanomanufacturing Taxonomy
lists: Interaction Network Ontology
lists: International Classification of External Causes of Injuries
lists: International Classification of Diseases Version 10
lists: International Classification of Diseases Version 10 - Clinical Modification
lists: International Classification of Diseases Version 10 - Procedure Coding System
lists: MR dataset acquisition
lists: Maize Gross Anatomy Ontology
lists: Major Histocompatibility Complex Ontology
lists: Medical image simulation
lists: Menelas Project Top-Level Ontology
lists: Mental State Assessment
lists: Metagenome Sample Vocabulary
lists: Metagenome and Microbes Environmental Ontology
lists: MicroRNA Ontology
lists: Microbial Culture Collection Vocabulary
lists: Microbial Typing Ontology
lists: Minimal Information about any Sequence Controlled Vocabularies
lists: Minimal Information about any Sequence Ontology
lists: NIF Dysfunction Ontlogy
lists: NIF Subcellular Ontology
lists: NMR-Instrument Component of Metabolomics Investigations Ontology
lists: Name Reaction Ontology
lists: NanoParticle Ontology
lists: National Cancer Institute Thesaurus
lists: National Drug Data File
lists: National Drug File - Reference Terminology
lists: Natural Products Ontology
lists: Neglected Tropical Disease Ontology
lists: Neomark Oral Cancer Ontology version 3
lists: Neomark Oral Cancer Ontology version 4
lists: Neural Motor Recovery Ontology
lists: NeuroMorpho.Org species ontology
lists: NeuroMorpho.Org species ontology old
lists: Non-Randomized Controlled Trials Ontology
lists: Nursing Care Coordination Ontology
lists: Ontological Knowledge Base Model for Cystic Fibrosis
lists: Ontology for Drug Discovery Investigations
lists: Ontology for General Medical Science
lists: Ontology for Genetic Disease Investigations
lists: Ontology for Genetic Susceptibility Factor
lists: Ontology for MicroRNA Target Prediction
lists: Symptom Ontology
lists: Ontology for Newborn Screening Follow-up and Translational Research
lists: Ontology of Alternative Medicine French
lists: Ontology of Biological and Clinical Statistics
lists: Ontology of Clinical Research
lists: Ontology of Core Data Mining Entities
lists: Ontology of Data Mining Investigations
lists: Pediatric Terminology
lists: Ontology of Experimental Variables and Values
lists: Ontology of General Purpose Datatypes
lists: Ontology of Geographical Region
lists: Ontology of Glucose Metabolism Disorder
lists: Ontology of Homology and Related Concepts in Biology
lists: Ontology of Language Disorder in Autism
lists: Orphanet Rare Disease Ontology
lists: Parasite Experiment Ontology
lists: Pathogen Transmission Ontology
lists: Pathogenic Disease Ontology
lists: Pharmacogenomic Relationships Ontology
lists: Physico-Chemical Methods and Properties
lists: Plant Anatomy
lists: Syndromic Surveillance Ontology
lists: Plant Structure Development Stage
lists: Portfolio Management Application
lists: Protein Modification Ontology
lists: Protein-Protein Interaction Ontology
lists: Proteomics Data and Process Provenance Ontology
lists: Provenance Ontology
lists: QUDT
lists: Quantitative Imaging Biomarker Ontology
lists: Radiology Lexicon
lists: Robert Hoehndorf Version of MeSH
lists: Role Ontology
lists: STATistics Ontology
lists: Sage Bionetworks Synapse Ontology
lists: Sample Processing and Separation Techniques Ontology
lists: Santa Barbara Coastal Observation Ontology
lists: Semantic Types Ontology
lists: Semantic Web for Earth and Environment Technology Ontology
lists: Semanticscience Integrated Ontology
lists: Single-Nucleotide Polymorphism Ontology
lists: Situation-Based Access Control Ontology
lists: Taxonomic Rank Vocabulary
lists: Taxonomy for Rehabilitation of Knee Conditions
lists: Terminological and Ontological Knowledge Resources Ontology
lists: Tick Gross Anatomy Ontology
lists: Tissue Microarray Ontology
lists: Traditional Medicine Constitution Value Set
lists: Traditional Medicine Meridian Value Sets
lists: Traditional Medicine Other Factors Value Set
lists: Traditional Medicine Signs and Symptoms Value Set
lists: Translational Medicine Ontology
lists: Tribolium Ontology
lists: Units Ontology
lists: Units of Measurement Ontology
lists: Upper-Level Cancer Ontology
lists: Vertebrate Homologous Organ Group Ontology
lists: Veterans Health Administration National Drug File
lists: Vital Sign Ontology
lists: WHO Adverse Reaction Terminology
lists: Web-Service Interaction Ontology
lists: Wheat Trait Ontology
lists: XEML Environment Ontology
lists: suicideo
lists: suicideonto
lists: Pseudogene
lists: Terminology for the Description of Dynamics
lists: Gene Regulation Ontology
lists: UBERON
lists: CHEBI
lists: Cognitive Paradigm Ontology
lists: Emotion Ontology
lists: Clinical Measurement Ontology
lists: Measurement Method Ontology
lists: NCI Thesaurus
lists: Ontology for Biomedical Investigations
lists: Biological Pathways Exchange
is listed by: Biositemaps
is listed by: FORCE11
is related to: Provisional Cell Ontology
has parent organization: National Center for Biomedical Ontology
has parent organization: Stanford University; Stanford; California
has parent organization: Stanford Center for Biomedical Informatics Research
is parent organization of: NCBO Annotator
NIGMS U24 GM143402 PMID:19483092
PMID:21672956
PMID:18999306
Free, Available for download, Freely available nif-0000-23346, r3d100012344 https://www.force11.org/node/4646, https://doi.org/10.17616/R3J362 SCR_002713 BioPortal Knowledgebase 2026-08-04 09:40:43 328
Molecular Simulation Trajectories Archive of a Villin Variant
 
Resource Report
Resource Website
Molecular Simulation Trajectories Archive of a Villin Variant (RRID:SCR_002704) Molecular Simulation Trajectories Archive of a Villin Variant data set, d spatial image, data or information resource An archive of hundreds of all-atom, explicit solvent molecular dynamics simulations that were performed on a set of nine unfolded conformations of a variant of the villin headpiece subdomain (HP-35 NleNle). It includes scripts for accessing the archive of villin trajectories as well as a VMD plug-in for viewing the trajectories. In addition, all starting structures used in the trajectories are also provided. The simulations were generated using a distributed computing method utilizing the symmetric multiprocessing paradigm for individual nodes of the Folding_at_home distributed computing network. The villin trajectories in the archive are divided into two projects: PROJ3036 and PROJ3037. PROJ3036 contains trajectories starting from nine non-folded configurations. PROJ3037 contains trajectories starting from the native (folded) state. Runs 0 through 8 (in PROJ3036) correspond to starting configurations 0 through 8 discussed in the paper in J. Mol. Biol. (2007) 374(3):806-816 (see the publications tab for a full reference), whereas RUN9 uses the same starting configuration as RUN8. Each run contains 100 trajectories (named clone 0-99), each with the same starting configuration but different random velocities. Trajectories vary in their length of time and are subdivided into frames, also known as a generation. Each frame contains around 400 configurational snapshots, or timepoints, of the trajectory, with the last configurational snapshot of frame i corresponding to the first configurational snapshot of generation i+1. The goal is to allow researchers to analyze and benefit from the many trajectories produced through the simulations. dynamic, atom, headpiece, molecular, simulation, solvent, protein folding, villin, molecule, trajectory, simulation, molecular dynamics trajectory is listed by: Biositemaps
has parent organization: Simtk.org
Stanford University; California; USA ;
Graduate Fellowship ;
NIH ;
NIGMS R01-GM062868;
NSF MCB-0317072
PMID:17950314 Acknowledgement requested, Available in Gromacs and PDB formats. nif-0000-23331 SCR_002704 2026-08-04 09:40:43 0
PRO
 
Resource Report
Resource Website
1+ mentions
PRO (RRID:SCR_002902) ontology, data or information resource, controlled vocabulary An ontological representation of protein-related entities, explicitly defining them and showing the relationships between them. Each PRO term represents a distinct class of entities (including specific modified forms, orthologous isoforms, and protein complexes) ranging from the taxon-neutral to the taxon-specific. PRO encompasses three sub-ontologies: proteins based on evolutionary relatedness (ProEvo); protein forms produced from a given gene locus (ProForm); and protein-containing complexes (ProComp). protein is listed by: OMICtools
has parent organization: Protein Information Resource
NIGMS 5R01GM080646-09 PMID:21929785 OMICS_06200 SCR_002902 Protein Ontology 2026-08-04 09:40:46 4
Cytoscape
 
Resource Report
Resource Website
10000+ mentions
Cytoscape (RRID:SCR_003032) data processing software, data analysis software, software resource, software application, data visualization software Software platform for complex network analysis and visualization. Used for visualization of molecular interaction networks and biological pathways and integrating these networks with annotations, gene expression profiles and other state data. biological, network, visualization, analysis, data, gene, pathway, molecular, interaction, FASEB list is used by: CytoSPADE
is used by: HDBase
is used by: DisGeNET
is used by: categoryCompare
lists: PEPPER
is listed by: Debian
is listed by: SoftCite
is related to: PhosphoSitePlus: Protein Modification Site
is related to: TRIP Database
is related to: CoryneRegNet
is related to: AltAnalyze - Alternative Splicing Analysis Tool
is related to: MiMI Plugin for Cytoscape
is related to: Network Data Exchange (NDEx)
is related to: GeneMANIA
is related to: DroID - Drosophila Interactions Database
is related to: Network-based Prediction of Human Tissue-specific Metabolism
is related to: Biological General Repository for Interaction Datasets (BioGRID)
is related to: DaTo
is related to: PiNGO
is related to: iBIOFind
is related to: cPath
is related to: BiNGO: A Biological Networks Gene Ontology tool
is related to: ClueGO
is related to: RamiGO
is related to: EGAN: Exploratory Gene Association Networks
has parent organization: Institute for Systems Biology; Washington; USA
has parent organization: University of California at San Diego; California; USA
is parent organization of: JEPETTO
has plug in: CluePedia Cytoscape plugin
has plug in: CytoSPADE
has plug in: EnrichmentMap
has plug in: cytoHubba
has plug in: iRegulon
works with: NetCirChro
works with: IMEx - The International Molecular Exchange Consortium
works with: yFiles Layout Algorithms
works with: RCy3
National Resource for Network Biology ;
NCRR RR031228;
NIGMS GM070743
PMID:21149340
PMID:14597658
Free, Available for download, Freely available nif-0000-30404 https://sources.debian.org/src/cytoscape/ SCR_003032 Complex Network Analysis Visualization, Cytoscape 2.6, Cytoscape 3.0 2026-08-04 09:40:48 23431
BioPerl
 
Resource Report
Resource Website
100+ mentions
BioPerl (RRID:SCR_002989) BioPerl source code, software resource, software repository, wiki, narrative resource, software toolkit, data or information resource BioPerl is a community effort to produce Perl code which is useful in biology. This toolkit of perl modules is useful in building bioinformatics solutions in Perl. It is built in an object-oriented manner so that many modules depend on each other to achieve a task. The collection of modules in the bioperl-live repository consist of the core of the functionality of bioperl. Additionally auxiliary modules for creating graphical interfaces (bioperl-gui), persistent storage in RDMBS (bioperl-db), running and parsing the results from hundreds of bioinformatics applications (Run package), software to automate bioinformatic analyses (bioperl-pipeline) are all available as Git modules in our repository. The BioPerl toolkit provides a library of hundreds of routines for processing sequence, annotation, alignment, and sequence analysis reports. It often serves as a bridge between different computational biology applications assisting the user to construct analysis pipelines. This chapter illustrates how BioPerl facilitates tasks such as writing scripts summarizing information from BLAST reports or extracting key annotation details from a GenBank sequence record. BioPerl includes modules written by Sohel Merchant of the GO Consortium for parsing and manipulating OBO ontologies. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible perl, biology, ontology, library, sequence, analysis, computational, application, pipeline, bioinformatics, sequence, annotation, module, life science, python, java, genome, software library, parse, manipulate, bio.tools is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
is related to: Gene Ontology
is related to: OBO
has parent organization: Duke University; North Carolina; USA
has parent organization: European Bioinformatics Institute
is required by: RelocaTE
NIGMS T32 GM07754-22;
NHGRI K22 HG00056;
NHGRI K22 HG-00064-01;
NHGRI HG00739;
NHGRI P41HG02223
PMID:12368254
DOI:10.1101/gr.361602
Free, Available for download, Freely available OMICS_04849, nif-0000-30188, biotools:bioperl https://bio.tools/bioperl, https://sources.debian.org/src/bioperl/ SCR_002989 2026-08-04 09:40:47 402
Gene Set Enrichment Analysis
 
Resource Report
Resource Website
10000+ mentions
Gene Set Enrichment Analysis (RRID:SCR_003199) GSEA data processing software, data analysis software, software resource, software application, software toolkit Software package for interpreting gene expression data. Used for interpretation of a large-scale experiment by identifying pathways and processes. gene, expression, profile, pathway, data, set, phenotype, genome, enrichment, RNA, analysis, bio.tools, bio.tools is used by: Molecular Signatures Database
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GoMapMan
has parent organization: Broad Institute
NCI ;
NIH ;
NIGMS
PMID:16199517 Free, Freely available nif-0000-30629, SCR_016882, biotools:gsea, OMICS_02279 http://www.broad.mit.edu/gsea, https://bio.tools/gsea SCR_003199 GSEA, Gene Set Enrichment Analysis, Gene Set Enrichment Analysis (GSEA) 2026-08-04 09:40:50 18865
IMOD
 
Resource Report
Resource Website
1000+ mentions
IMOD (RRID:SCR_003297) IMOD data processing software, source code, software resource, software application, image processing software, image analysis software A free, cross-platform set of image processing, modeling and display programs used for tomographic reconstruction and for 3D reconstruction of EM serial sections and optical sections. The package contains tools for assembling and aligning data within multiple types and sizes of image stacks, viewing 3-D data from any orientation, and modeling and display of the image files. IMOD 4.1.8 Is Now Available for Linux, Windows, and Mac OS X electron microscopy, magnetic resonance, tomographic reconstruction, reconstruction, segmentation, 3d volume is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: SoftCite
has parent organization: University of Colorado Boulder; Colorado; USA
NCRR ;
NIGMS ;
NIBIB
PMID:27444392 Free, Available for download, Freely available nif-0000-31686 http://www.nitrc.org/projects/imod SCR_003297 IMOD - 3D Reconstruction and Analysis 2026-08-04 09:40:52 1585
RNA Modification Database
 
Resource Report
Resource Website
10+ mentions
RNA Modification Database (RRID:SCR_003535) RNAmods storage service resource, data repository, service resource, database, data or information resource The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from RNA. Information provided for each nucleoside includes: the type of RNA in which it occurs and phylogenetic distribution; common chemical name and symbol; Chemical Abstracts registry number and index name; chemical structure; initial literature citations for structural characterization or occurrence, and for chemical synthesis. Both the structural diversity and extent of posttranscriptional modification in RNA is remarkable, with 107 different nucleosides presently known in all types of RNA. The discovery of new modified nucleosides as well as increasing knowledge of the array of functional roles of modification, based largely on extensive studies of tRNA, mandates a need for a comprehensive database of RNA nucleosides. The RNA Modification Database is maintained as an extension of the initial version published in mid-1994. The database consists of all RNA-derived ribonucleosides of known structure, including those from established sequence positions, as well as those detected or characterized from hydrolysates of RNA. The information provided permits access to the modified nucleoside literature through provision of both computer-searchable Chemical Abstracts registry numbers and key literature citations. This database also provides an historical record of the initial reports of occurrence, characterization and chemical synthesis of modified nucleosides from RNA. It is our judgement that the total number of RNA nucleosides listed, and the chemical structures reported, are very accurate. However, the distributions listed are in some cases a matter of concern, due primarily to the possibility of inhomogeneity of the RNA isolate and the use of methods of nucleoside identification that are not sufficiently rigorous. Reinvestigation of some of the unusual or single-report source distributions is warranted, and will likely lead to future refinements in the listings. The authors invite comments concerning new entries, errors or omissions and on the format presently used for electronic access to the database. has parent organization: University at Albany; New York; USA
has parent organization: University of Utah; Utah; USA
NIGMS GM29812 PMID:9399834
PMID:9016519
nif-0000-03414 http://medlib.med.utah.edu/RNAmods/ SCR_003535 2026-08-04 09:40:56 22
MEGA
 
Resource Report
Resource Website
1000+ mentions
MEGA (RRID:SCR_000667) MEGA, MEGA6, MEGA4, MEGA 4, MEGA 11 data processing software, data analysis software, software resource, sequence analysis software, software application, software toolkit Software integrated tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web based databases, estimating rates of molecular evolution, and testing evolutionary hypotheses. Used for comparative analysis of DNA and protein sequences to infer molecular evolutionary patterns of genes, genomes, and species over time. MEGA version 4 expands on existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence alignment, analyzing sequence alignments to estimate evolutionary distances, inferring phylogenetic trees, and testing evolutionary hypotheses. MEGA version 6 enables inference of timetrees, as it implements RelTime method for estimating divergence times for all branching points in phylogeny. comparative, analysis, DNA, protein, sequence, molecular, evolution, pattern, gene, genome, evolution, FASEB list has parent organization: Pennsylvania State University Japan Society for the Promotion of Science ;
NHGRI HG006039;
NHGRI HG002096;
Burroughs-Wellcome Fund ;
NIGMS R01GM126567;
NSF ABI 1661218;
NIGMS R35GM139504
DOI:10.1093/molbev/msab120
PMID:24132122
PMID:31904846
PMID:22923298
PMID:21546353
PMID:17488738
PMID:15260895
PMID:11751241
PMID:8019868
Free, Available for download, Freely available SCR_023017, nlx_156838 https://www.megasoftware.net/mega4/ SCR_000667 MEGA11, Molecular Evolutionary Genetics Analysis, Molecular Evolutionary Genetics Analysis 6, Molecular Evolutionary Genetics Analysis 4 2026-08-04 09:40:11 2763
Structure-function linkage database
 
Resource Report
Resource Website
10+ mentions
Structure-function linkage database (RRID:SCR_001375) SFLD database, data or information resource A database of hierarchical classification of enzymes that relates specific sequence-structure features to specific chemical capabilities. The SFLD classifies evolutionarily related enzymes according to shared chemical functions and maps these shared functions to conserved active site features. The classification is hierarchical, where broader levels encompass more distantly related proteins with fewer shared features. It thus serves as the analysis and archive site for superfamilies targeted by the Enzyme Function Initiative, and is developed by the Babbitt Laboratory in collaboration with the UCSF Resource for Biocomputing, Visualization, and Informatics. The resource also provides a collection of tools and data for investigating sequence-structure-function relationships and hypothesizing function. software, enzyme, structure-function relationship, blast, reaction, superfamily, hidden markov model, sequence alignment, protein similarity network, sequence, structure, function uses: UCSF Chimera
has parent organization: Resource for Biocomputing Visualization and Informatics
NIGMS R01GM60595;
NIGMS P01GM071790;
NIGMS U54GM093342
PMID:18428763
PMID:16489747
Free, Freely available, nlx_152532 SCR_001375 2026-08-04 09:40:21 17
MassQL
 
Resource Report
Resource Website
1+ mentions
MassQL (RRID:SCR_025106) software resource, source code Software application for universal searching of Mass Spectrometry data. Open source MS query language for flexible and mass spectrometer manufacturer-independent mining of MS data. Implements common MS terminology to build consensus vocabulary to search for MS patterns in single mass spectrometry run. Enables set of mass spectrometry patterns to be queried directly from raw data. Mass Spectrometry data searching, mass spectrometry data, mining of MS data, common MS terminology, mass spectrometry patterns, raw data query, NIGMS R01 GM125943;
NIGMS R01 GM107550;
NIGMS R35 GM128690;
NIAID R21 AI156669;
NIAID R15 AI137996;
NSF ;
Burroughs Wellcome Fund ;
University of Michigan ;
National Research Foundation of Korea ;
German Research Foundation ;
Swedish Research Council ;
Ministry of Innovative Development of the Republic of Uzbekistan ;
German Ministry for Education and Research ;
Horizon 2020 programme of the European Union ;
Czech Science Foundation ;
U.S. Department of Energy Joint Genome Institute ;
National Cancer Center Research and Development Fund ;
AMED Japan Program for Infectious Diseases Research and Infrastructure ;
Novo Nordisk Foundation ;
Denmark ;
Betty and Gordon Moore Foundation
DOI:10.1101/2022.08.06.503000 Free, Available for download, Freely available https://pypi.org/project/massql/ SCR_025106 Mass Spec Query Language 2026-08-03 09:39:00 1
WASP
 
Resource Report
Resource Website
1+ mentions
WASP (RRID:SCR_025497) software toolkit, software resource, source code Software allele-specific pipeline for unbiased read mapping and molecular QTL discovery. Allele-specific software for robust molecular quantitative trait locus discovery. molecular QTLs discovery, unbiased allele-specific read mapping and discovery, molecular QTLs, unbiased allele-specific read, mapping and discovery, Howard Hughes Medical Institute ;
NHGRI HG007036;
NHGRI HG006123;
NIMH MH101825;
NIGMS GM007197;
NSF
PMID:26366987 Free, Available for download, Freely available, SCR_025497 2026-08-03 09:39:09 3
ALFRED
 
Resource Report
Resource Website
50+ mentions
ALFRED (RRID:SCR_001730) ALFRED storage service resource, data repository, service resource, database, data or information resource A public curated compilation of allele frequency data on anthropologically defined human population samples linked to the molecular genetics-human genome databases. Only data on well defined population samples that are large enough to yield reasonably accurate frequencies and for polymorphisms sufficiently defined to be replicable can be included in ALFRED. Researchers wishing to have their data entered into ALFRED should contact them. Initially, ALFRED contained primarily data generated in the laboratories of K.K. and J.R. Kidd in the Department of Genetics at Yale, including extensive unpublished data. Data from the published literature are being entered into ALFRED in a systematic way, with a focus on polymorphisms studied in many different populations. ALFRED is distinct from such databases as dbSNP, which catalogs sequence variation. ALFRED's focus is on allele frequencies in diverse anthropologically defined populations. It is not a compendium of human DNA polymorphisms but of frequencies of selected polymorphisms with an emphasis on those that have been studied in multiple populations. All of the data in ALFRED are considered to be in the public domain and available for use in research and teaching. ALFRED provides easy searching options including versatile "Keyword search" and also has numerous summary tables providing quick overviews of contents by chromosome, population, average heterozygosity, Fst and others, all available under various tabs from the ALFRED homepage. allele frequency, dna polymorphism, haplotype, high throughput, genome, population, sample, education, polymorphism, allele, chromosome, heterozygosity, fst, loci, pathway, genetics, FASEB list has parent organization: Yale School of Medicine; Connecticut; USA NIGMS P01GM 57672 PMID:19325849
PMID:11125124
PMID:12209575
Free, Freely Available nif-0000-02541, r3d100012700 https://doi.org/10.17616/R3GZ2J SCR_001730 The ALlele FREquency Database, ALlele FREquency Database 2026-08-04 09:40:27 71
ASAP
 
Resource Report
Resource Website
50+ mentions
ASAP (RRID:SCR_001849) ASAP storage service resource, data repository, service resource, database, data or information resource Database and web interface developed to store, update and distribute genome sequence data and gene expression data. ASAP was designed to facilitate ongoing community annotation of genomes and to grow with genome projects as they move from the preliminary data stage through post-sequencing functional analysis. The ASAP database includes multiple genome sequences at various stages of analysis, and gene expression data from preliminary experiments. Use of some of this preliminary data is conditional, and it is the users responsibility to read the data release policy and to verify that any use of specific data obtained through ASAP is consistent with this policy. There are four main routes to viewing the information in ASAP: # a summary page, # a form to query the genome annotations, # a form to query strain collections, and # a form to query the experimental data. Navigational buttons appear on every page allowing users to jump to any of these four points., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene expression, genome, genome sequence, multiple genome sequence, post sequencing functional analysis, preliminary experiment, blast, annotation, data analysis service is used by: NIF Data Federation
is listed by: SoftCite
is related to: AmiGO
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
USDA 2001-52100-11316;
NIGMS GM62994-02;
NIGMS GM35682-15A1
PMID:12519969 Free, Freely available nif-0000-02571, r3d100010666 https://omictools.com/asap-3-tool SCR_001849 A Systematic Annotation Package for Community Analysis of Genome, ASAP: a systematic annotation package for community analysis of genomes, A systematic annotation package for community analysis of genomes 2026-08-04 09:40:29 53

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