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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Oldest and largest public university established in 1965 in Lusaka. Operating under the motto "Service and Excellence," it offers over 150 undergraduate and postgraduate programs across 13 schools, with major campuses at Great East Road and Ridgeway.
Proper citation: University of Zambia; Lusaka; Zambia (RRID:SCR_028150) Copy
Database offers integrated multi-omic data for patients across 33 cancer types. It encompasses gene expression, DNA methylation, somatic mutations, proteomic profiles, and chromatin accessibility, drawing from TCGA, GTEx, and CPTAC projects. Users can compare gene expression, DNA methylation, and protein levels between tumor and normal tissues, identifying differentially expressed genes and proteins, and examining gene-to-gene correlations. Provides oncogene mutation profiles and allows for survival analysis based on gene expression and methylation, linked to clinical parameters. Facilitates exploration of multi-omic correlations, such as gene expression with DNA methylation, and their variations with mutation status. Extends its analytical capabilities to include six major oncoviruses, offering insights into their impact on gene expression, methylation, and patient survival.
Proper citation: OncoDB (RRID:SCR_028340) Copy
Database of glycans 3D structural data and information that can be downloaded or used with Re-Glyco to rebuild glycoproteins from the RCSB PDB or EMBL-EBI AlphaFold repositories. Glycan structure database and toolbox designed to restore glycoproteins to their native and functional form.
Proper citation: GlycoShape (RRID:SCR_028443) Copy
Spectrometer used for advanced chemical, biological, and materials research. It allows scientists to determine the atomic-level structure, dynamics, and interactions of molecules. Console: Avance Neo; Magnet: Ascend; Field Strength: 800 MHz; software:TopSpin 4.4.1 on CentOS 7; Probe: 5mm QXI-F solution; 5mm TXI solution; 4.0mm gradient hr-MAS; 3.2mm Efree; 2.5mm Tri-gamma MAS; 1.9mm MAS; 1.3mm MAS; 0.7mm ultra-fast MAS.
Proper citation: Bruker: Avance Neo Ascend 800 MHz NMR Spectrometer (RRID:SCR_028511) Copy
https://www.labservis.com/en/cobas_8000_analyzer_series_e602
Immunochemistry analyzer as mid-volume throughput immunochemistry module that performs broad range of heterogeneous immunoassay tests using ElectroChemiLuminescence (ECL) technology. Offers Heterogeneous immunoassays, Throughput of up to 170 tests/hour, 25 reagent positions, Reagent cassette loading/unloading during standby, Carryover-free disposable tips, Clot and air bubble detection.
Proper citation: Roche: cobas e 602 analytical unit (RRID:SCR_026640) Copy
Platform to help scientists organize all biological knowledge into singular, unified resource that is searchable, accessible and capable of answering the most difficult questions in science. Used for bioinformatics analysis.
Proper citation: BioBox (RRID:SCR_026642) Copy
https://www.corelaboratory.abbott/us/en/offerings/brands/architect/architect-i2000SR.html
Analyzer offers maximum throughput of up to 200 tests per hour. Featuring load-up capacity of 135 samples with 35 priority and 100 routine areas. Has 25 refrigerated reagent positions. Designed for efficient and accurate analysis of various biological samples, including serum, plasma, and other bodily fluids.
Proper citation: Abbott: ARCHITECT i2000SR immunoassay analyzer (RRID:SCR_026638) Copy
Agilent Seahorse XF Pro analyzer measures and reports the oxygen consumption rate (OCR), proton efflux rate (PER) or extracellular acidification rate (ECAR), as well as ATP production rates of live cells in a 96-well format. This analyzer features excellent OCR precision at low rates, verified performance, optimized temperature control, and is automation enabled. The XF Pro analyzer is also equipped with advanced software, standardized workflows, and advanced data analytics available in the Agilent Seahorse Analytics software. These features greatly simplify the entire XF assay experience, from assay design to data QC and interpretation.
Proper citation: Agilent: Seahorse XF Pro Analyzer (RRID:SCR_026694) Copy
https://endomap.hms.harvard.edu/
Structural interactome viewer. Interactive database of endosomal protein-protein interactions identified by cross-linking mass spectrometry and modeled by AlphaFold multimer. Structural protein interactome of human early endosomes.
Proper citation: EndoMap (RRID:SCR_026690) Copy
https://www.leica-microsystems.com/products/light-microscopes/p/dmi8/
Leica DMi8 microscope is an inverted light microscope, intended as a general microscope for routine examinations of biological specimens.
Proper citation: Leica: DMi8 Inverted Microscope (RRID:SCR_026672) Copy
https://azurebiosystems.com/products/azure-imaging-systems/azure-300/
Multichannel, multimodal imager, with visible fluorescence, visible light, and UV excitation channels. The system is fully upgradeable to fluorescent Western Blot Imaging System.
Proper citation: Azure Biosystems: Chemiluminescent Western Blot Imager Azure 300 (RRID:SCR_026671) Copy
https://www.ddg-pharmfac.net/epijen/EpiJen/EpiJen.htm
Web server for multistep T cell epitope prediction. Also considers proteasome cleavage and TAP binding, therefore it is able to mimic the MHC binding machnism in real life. At present only HLA class I alleles are included in the prediction.
Proper citation: EpiJen (RRID:SCR_026689) Copy
Compact stereotaxic instrument designed for use with knock-out and transgenic mice. Instrument includes 100 micron, 3-axes left-hand manipulator arm, mouse snout clamp and tooth bar, dual-sided ear bars, and corner clamp probe holder. Stoelting’s Motorized Stereotaxic Manipulator Arms are designed for fast, accurate positioning during stereotaxic surgery. Motorized manipulator arms employ touchscreen display for easy-to-control movement of each axis. Manual movement is available anytime. Optional Drill feature available.
Proper citation: RWD Life Science: Standard Stereotaxic Holder (RRID:SCR_026656) Copy
3D-Hub-O specializes in production, manipulation and analysis of organoids from normal and tumor tissues. Physiological platform for research on living pathological tissues. Platform participates in knowledge transfer through customized training of specific organoid culture carried out by platform staff.
Proper citation: 3D-Hub-O platform (RRID:SCR_026655) Copy
Interactive web application for drug screening data analysis. It includes comprehensive quality control statistics, dose-response curve fitting, and calculation of quantitative scoring parameters such as EC50, IC50, drug sensitivity score and AUC. Used to facilitate quality control, dose-response curve fitting, and data visualization.
Proper citation: Breeze web-tool (RRID:SCR_026646) Copy
http://ubibrowser.bio-it.cn/ubibrowser
Web application as resource of known and predicted human ubiquitin ligase substrate interaction network. E3-substrate interactions are derived from six data sources: mannual cruration, protein ortholog, protein domain, protein motif and network topology.Designed to explore predicted and reported E3-substrate interactions for query E3 or substrate, and ubiquitination sites for substrate protein.
Proper citation: Ubibrowser (RRID:SCR_026659) Copy
https://healthsurveys.ipums.org/
Integrated Public Use Microdata Series Health Surveys provide free individual-level survey data for research purposes from two leading sources of self-reported health and health care access information: the National Health Interview Survey (NHIS) and the Medical Expenditure Panel Survey (MEPS).
Proper citation: IPUMS Health Surveys (RRID:SCR_026762) Copy
Varioskan LUX is modular, upgradable instrument that offers usability for range of applications. Reader for absorbance, fluorescence intensity, chemiluminescence, AlphaScreen, and time-resolved fluorescence.
Proper citation: Thermo Fisher: Varioskan LUX Multi-Mode Microplate Reader (RRID:SCR_026792) Copy
https://www.ncei.noaa.gov/erddap/index.html
Data server to download subsets of scientific datasets in common file formats and make graphs and maps. This particular ERDDAP installation has oceanographic data (for example, data from satellites and buoys).
Proper citation: ERDDAP (RRID:SCR_026784) Copy
Database that attempts to consolidate information on known clinical and selected set of pre-clinical biomarkers into single resource. Database includes five major types of biomarkers (condition specific, protein, chemical, karyotypic and genetic) and six biomarker categories (diagnostic, risk, prognostic, safety, monitoring, and response). Provides information such as: biomarker names and synonyms, associated conditions or pathologies, detailed disease descriptions, detailed biomarker descriptions, biomarker specificity, sensitivity and ROC curves, standard reference values (for protein and chemical markers), variants (for SNP or genetic markers), sequence information (for genetic and protein markers), molecular 2D and 3D structures (for protein and chemical markers), tissue or biofluid sources (for protein and chemical markers), chromosomal location and structure (for genetic and karyotype markers), clinical approval status and relevant literature references. Users can browse the data by conditions, condition categories, biomarker types, biomarker categories or search by sequence similarity through the advanced search function.
Proper citation: MarkerDB (RRID:SCR_026817) Copy
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