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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.meta-analysis.com/index.php
A software package to do meta-analysis which works in a spreadsheet interface and also provides forest plots, which are useful for visualizing between-study heterogeneity.
Proper citation: CMA (RRID:SCR_012779) Copy
http://www.cdc.gov/nchs/lsoa.htm
A data set of a multicohort study of persons 70 years of age and over designed primarily to measure changes in the health, functional status, living arrangements, and health services utilization of two cohorts of Americans as they move into and through the oldest ages. The project is comprised of four surveys: * The 1984 Supplement on Aging (SOA) * The 1984-1990 Longitudinal Study of Aging (LSOA) * The 1994 Second Supplement on Aging (SOA II) * The 1994-2000 Second Longitudinal Study of Aging (LSOA II) The surveys, administered by the U.S. Census Bureau, provide a mechanism for monitoring the impact of proposed changes in Medicare and Medicaid and the accelerating shift toward managed care on the health status of the elderly and their patterns of health care utilization. SOA and SOA II were conducted as part of the in-person National Health Interview Survey (NHIS) of noninstitutionalized elderly people aged 55 years and over living in the United States in 1984, and at least 70 years of age in 1994, respectively. The 1984 SOA served as the baseline for the LSOA, which followed all persons who were 70 years of age and over in 1984 through three follow-up waves, conducted by telephone in 1986, 1988, and 1990. The SOA covered housing characteristics, family structure and living arrangements, relationships and social contracts, use of community services, occupation and retirement (income sources), health conditions and impairments, functional status, assistance with basic activities, utilization of health services, nursing home stays, and health opinions. Most of the questions from the SOA were repeated in the SOA II. Topics new to the SOA II included use of assistive devices and medical implants; health conditions and impairments; health behaviors; transportation; functional status, assistance with basic activities, unmet needs; utilization of health services; and nursing home stays. The major focus of the LSOA follow-up interviews was on functional status and changes that had occurred between interviews. Information was also collected on housing and living arrangements, contact with children, utilization of health services and nursing home stays, health insurance coverage, and income. LSOA II also included items on cognitive functioning, income and assets, family and childhood health, and more extensive health insurance information. The interview data are augmented by linkage to Medicare enrollment and utilization records, the National Death Index, and multiple cause-of-death records. Data Availability: Copies of the LSOA CD-ROMs are available through the NCHS or through ICPSR as Study number 8719. * Dates of Study: 1984-2000 * Study Features: Longitudinal * Sample Size: ** 1984: 16,148 (55+, SOA) ** 1984: 7,541(70+, LSOA) ** 1986: 5,151 (LSOA followup 1) ** 1988: 6,921 (LSOA followup 2) ** 1990: 5,978 (LSOA followup 3) ** 1994-6: 9,447 (LSOA II baseline) ** 1997-8: 7,998 (LSOA II wave 2) ** 1999-0: 6,465 (LSOA II wave 3) Link: * LSOA 1984-1990 ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/08719
Proper citation: Longitudinal Studies of Aging (RRID:SCR_013355) Copy
http://www.nitrc.org/projects/hfh_t1_hp_seg1/
Shared dataset which consists of skull-stripped T1 MRI images and segmented hippocampi of 163 Temporal Lobe Epilepsy (TLE) patients. The T1 and hippocampal segmentation data of TLE patients are uploaded in three separate datasets which can be accessed from the main site.
Proper citation: Epilepsy T1 and Hippocampal Segmentation Datasets (RRID:SCR_014926) Copy
Orbitrap Exploris 120 LC-MS spectrometry instruments
Proper citation: Thermo Fisher: Orbitrap Exploris 120 high-resolution mass spectrometer (RRID:SCR_027370) Copy
https://bioinformatics.sdstate.edu/idep/
Integrated web application for differential expression and pathway analysis of RNA-Seq data.
Proper citation: iDEP: Integrated Differential Expression and Pathway analysis (RRID:SCR_027373) Copy
https://www.leica-microsystems.com/products/light-microscopes/p/leica-dmi4000-b/?country=DE
Microscope for scanning cell and tissue cultures. System features fluorescence axis for ultra brilliant fluorescence imaging.Internal filter wheel with motorized excitation manager and FIM (Fluorescence Intensity Manager) enables excitation of fluorochromes in less than 20 milliseconds.
Proper citation: Leica: DMI4000 B Automated Inverted Microscope (RRID:SCR_027345) Copy
https://microscopecentral.com/products/olympus-bx41-microscope
Olympus BX41 is clinical and research grade microscope. Can be customized. Offered as pre-configured with your choice of viewing head - binocular, ergo binocular, or trinocular. This has Plan N 4x, 10x, 40x, 100x oil objectives but others can be provided if needed. Comes with XY mechanical stage with slide holder and focusable condenser.
Proper citation: Olympus: BX41 Clinical Microscope (RRID:SCR_027355) Copy
https://www.toyobo-global.com/
Japanese company that began as a textile manufacturer in 1882 and has expanded to become a global provider of high-function products, including films, functional polymers, industrial materials, and biotechnology products such as enzymes and diagnostic reagents. The company's business is organized around its core technologies in polymerization, modification, processing, and biotechnology, allowing it to contribute to fields like healthcare, environment, and electronics.
Proper citation: TOYOBO (RRID:SCR_027440) Copy
https://github.com/SciCrunch/Antibody-Watch
Text mining antibody specificity from literature. Helps researchers identify potential problems with antibody specificity. By mining the scientific literature and linking findings to Research Resource Identifiers (RRIDs), it provides alerts on antibodies that may yield unreliable results, supporting reproducibility in biomedical research.
Proper citation: Antibody Watch (RRID:SCR_027424) Copy
https://www.revvity.com/product/ivis-spectrum-2-imaging-system-cls158738
In vivo optical imaging system used in preclinical research to non-invasively monitor and quantify biological processes in living animals over time. Designed with innovative camera with patented coating that delivers high sensitivity 2D and 3D bioluminescence and fluorescence imaging capabilities.
Proper citation: Revvity: IVIS Spectrum 2 In Vivo Imaging System (RRID:SCR_027425) Copy
https://biodataai.uth.edu/BRAINCELL-AID
Web service providing annotations for brain cell type–specific marker gene sets derived from single-cell RNA-seq data spanning the entire mouse brain. It uses a multi-agent AI framework that combines fine-tuned large language models with retrieval-augmented generation, producing biologically grounded annotations supported by peer-reviewed literature.
Proper citation: BRAINCELL-AID (RRID:SCR_027398) Copy
https://jaaba.sourceforge.net/
Web application to create variety of automatic behavior classifiers. These classifiers input the animals' trajectories computed by tracking system, and they output time series indicating whether each animal is performing a given behavior in each video frame. Interactive machine learning for automatic annotation of animal behavior. Used to automatically compute interpretable, quantitative statistics describing video of behaving animals.
Proper citation: Janelia Automatic Animal Behavior Annotator (RRID:SCR_027430) Copy
Target-to-Clinic Contract Research Organization (CRO) headquartered in San Diego, CA USA. ChemDiv executes pre-clinical discovery chemistry and biology for drug development and clinical trials for international portfolio of companies across the entire range of targets with small molecule and biotech drugs. The company operates multiple research and development (R&D) subsidiaries in Russia, Ukraine and China as well as business operations around the world.
Proper citation: ChemDiv (RRID:SCR_027402) Copy
https://www.jeol.com/products/scientific/sem/JCM-6000.php
Compact Benchtop Scanning Electron Microscope. Intuitive operation is achieved via touch panel and new operation screens. The high or low vacuum mode is included in the standard configuration, and EDS can be installed, offering truly multi-functional benchtop SEM.
Proper citation: JEOL: JCM-6000 Benchtop Scanning Electron Microscope (RRID:SCR_027403) Copy
https://www.bruker.com/en/products-and-solutions/mr/nmr/avance-nmr-spectrometer.html
Bruker’s Avance NMR spectrometers are utilized in various scientific fields to elucidate the structure, dynamics, and interactions of molecules. Avance spectrometers are composed of three main hardware components: console, which is the central control unit of the NMR spectrometer, and houses sophisticated electronics for the generation of the pulse sequences and for data acquisition and processing; superconducting magnet to generate homogenous and stable magnetic field to polarize the nuclear spins in the sample; probe for transmitting radiofrequency pulses and detecting the resulting signals from the sample.
Proper citation: Bruker: Avance NMR Spectrometer (RRID:SCR_027378) Copy
Updated knowledgebase integrating more curated associations in plants and animals. manually curated resource of genome-wide genotype-to-phenotype associations for a wide range of species. Database of publicly available GWAS summary statistics. Each GWAS can be browsed with the manhattan plot, risk loci, MAGMA (i.e. gene-based) results, SNP heritability and genetic correlations with other GWAS in the database. Full summary statistics can be downloaded from the original source following the provided links.
Proper citation: GWAS Atlas (RRID:SCR_027466) Copy
https://www.3dhistech.com/scanners/pannoramic-150-digital-scanner/
Digital pathology system designed for high-speed, high-resolution brightfield and fluorescence scanning. Equipped with continuously moving stage, advanced Plan-Apochromat optics including 10x objective, and a back-illuminated sCMOS camera. Capacity:150 slides (6 magazines, 25 slides each) with automatic loading and continuous scanning.Scanning:Dual-mode scanning (brightfield and fluorescence) with area scanning and autofocus.Motorized Camera ChangerIncluded, for seamless transitions between BF and FL imaging modes without manual intervention.Motorized Objective changer Included when two objectives are selected (supports two objectives).Brightfield Scanning Speed:1 minute 30 seconds for 15 mm x 15 mm area at 0.19 µm/pixel resolution. Fluorescence Scanning Speed:8 minutes 30 seconds for a 15 mm x 15 mm area with 3 fluorescent channels at 20 ms exposure time.Throughput Optimized for high-throughput workflows with fully automated slide handling. Objectives Plan-Apochromat 10x/0.3 NA, 20x/0.8 NA, and 40x Corr/0.95 NA objectives.Brightfield Magnification Up to 103x. Fluorescence Magnification Up to 98x (with 1.6x adapter). Image Output MRXS format with export options to JPG, JPEGXR, BMP, PNG, TIFF, Roche TIFF, SVS, and DICOM.Slide Compatibility: Slides measuring 75.0-76.2 mm (L) x 25.0-26.0 mm (W) x 0.9-1.2 mm (T) with No. 1 or 1.5 coverslips (0.13-0.19 mm).
Proper citation: 3DHISTECH: Pannoramic 150 Digital Scanner (RRID:SCR_027467) Copy
https://dmimedicalusa.com/product/aperio-at2-dx-system
400 slide scanner with Aperio ImageScope DX clinical viewing software, and high-performance viewing workstation including color-calibrated medical grade monitors. System can be used standalone, or in conjunction with Aperio Path DX case management software, for streamlined, clinical workflow. Developed from Leica Biosystems,enables to produce consistent, diagnostic quality images, enabling pathologists to diagnose with confidence.
Proper citation: Leica: Aperio AT2 DX System (RRID:SCR_027461) Copy
https://www.beckman.com/landing/ppc/liquid-handlers/synthetic-biology
Non-contact liquid handler that uses Acoustic Droplet Ejection (ADE) technology to precisely transfer nanoliter-sized droplets of liquid for high-throughput applications in pharmaceutical research, drug discovery, and various areas of genomics and biology. Echo 555 / 550 Liquid Handler: 2.5 nL increment; Flow rate:0.25 – 1 µL/sec; Ideal for reactions of 0.05 – 1 µL; Supports 384 and 1536-well source plate formats; Used for transfer of small molecules for high throughput screening.
Proper citation: Bechman Coulter: Labcyte Echo 550 acoustic liquid handler (RRID:SCR_027476) Copy
https://linkml.io/schemasheets/
Software tool aimed at data modelers, curators, wrangers, and creators of standards and datamodels. It is aimed at people who prefer to develop these standards using spreadsheet tools over more developer-centric tooling. Human-friendly spreadsheets with machine-actionable models.
Proper citation: SchemaSheets (RRID:SCR_027563) Copy
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