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The timsTOF SCP (single-cell proteomics) is mass spectrometer from Bruker. Ultra-high sensitivity instrument for quantitative single cell biology research with unbiased, deep single-cell 4D-Proteomics, immunopeptidomics, epiproteomics and PTM analysis. It features an additional separation in the tims cell where ions get separated according to their ion mobility, leading to collision cross-section values.Allows the analysis of hundreds of samples with minimal sample load (<200 ng) at sequencing speeds exceeding 100 Hz.
Proper citation: Bruker: timsTOF SCP mass spectrometer (RRID:SCR_026542) Copy
Mass spectrometry (MS)-based proteomics instrument designed for shotgun proteomics and phosphoproteomics, leveraging Parallel Accumulation Serial Fragmentation (PASEF) technology to enhance speed, sensitivity, and resolution.
Proper citation: Bruker: timsTOF Pro mass spectrometer (RRID:SCR_026544) Copy
Mass spectrometer is equipped with the 4th generation high capacity TIMS-XR analyzer and advanced digitizer technology (ADT). Offers higher dynamic range for unmatched analytical depth and quantitation in high-throughput proteomics experiments.
Proper citation: Bruker: timsTOF HT mass spectrometer (RRID:SCR_026543) Copy
Mass spectrometer used for research, particularly in proteomics and metabolomics, leveraging Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation Serial Fragmentation (PASEF) technologies for enhanced 4D-omics capabilities.
Proper citation: Bruker: timsTOF Pro 2 mass spectrometer (RRID:SCR_026545) Copy
https://www.microscope.healthcare.nikon.com/products/confocal-microscopes/ax
Confocal microscope provides enables collection of more data over wide area and down to deep regions in tissues. Its high sensitivity and high-speed scanning reduce phototoxicity to specimen and minimize damage. Equipped with image acquisition/analysis functions utilizing Artificial Intelligence (AI), the AX/AX R can efficiently acquire highly reliable data. Nikon Spatial Array Confocal (NSPARC) detector utilizes detector array to collect two-dimensional image at each scanned point. It adds additional potential to imaging by providing new level of ultra-low noise sensitive spatial detection, enabling improved lateral resolution of 1 airy unit/~230 nm and improved signal-to-noise ratio.
Proper citation: Nikon: AXR NSPARC super resolution inverted microscope (RRID:SCR_026538) Copy
https://www.marshallscientific.com/MJ-Research-PTC-200-Thermal-Cycler-p/mj-200.htm
Hot Bonnet heated lid fitted into PTC 200 Thermo Cycler controls pressure and height.Various plastic wares can be accommodated by system. Enables oil-free cycling.Equipped with interchangeable sample blocks and heat pump. Single control units of this model can also be supplied with different alpha modules and alpha blocks to increase functionality.
Proper citation: Marshall Scientific: J Research PTC-200 Thermal Cycler (RRID:SCR_025421) Copy
Impactor that allows for reproducible spinal cord and head contusions.
Proper citation: SeekGene: Scitech Korea Multicenter Animal Spinal Cord Injury Studies MASCIS impactor (RRID:SCR_025392) Copy
https://pghprecision.tripod.com/id2.html
Pneumatic-powered CCI device, with adjustable velocity and angle on impact used for neuroscience research.
Proper citation: Pittsburgh Precision Instruments: Cortical Controlled Impactor (RRID:SCR_025394) Copy
Provides catalogue of confirmed and predicted DNA replication origin sites. At present this is limited to budding yeast and fission yeast. Data have been collated as culmination of number of genome-wide studies to identify location of replication origins throughout budding yeast genome. In addition to genome-wide studies data from large number of other origin mapping and characterization studies have been included.
Proper citation: OriDB (RRID:SCR_025365) Copy
https://www.leicabiosystems.com/de/histology-equipment/cryostats/leica-cm1850-uv/
Cryostat for histopathology applications. Intended for cutting frozen sections of standard and non-standard materials. Designed to rapidly freeze material in temperature controlled environment. Has ability to quickly disinfect the cryo chamber at any time with ultra-violet light (UVC). The UV light is intended to reduce the user to significant dangers from bacteria, spores, and viruses.
Proper citation: Leica: CM 1850 UV cryostat (RRID:SCR_025401) Copy
https://www.researchspace.com/
Web next-gen digital research platform for Institutional Research Data Management. Fully integrated sample management and electronic lab notebook solution. Electronic lab notebook for physical sciences. Works with IGSN.
Proper citation: RSpace (RRID:SCR_025405) Copy
Software platform to annotate cell types.
Proper citation: Cellarium (RRID:SCR_025438) Copy
https://www.prisma-statement.org/protocols
Reporting guideline published in 2015 and aiming to facilitate the development and reporting of systematic review protocols.
Proper citation: PRISMA-P (RRID:SCR_025439) Copy
https://www.leicabiosystems.com/ihc-ish/ihc-ish-instruments/bond-rx/
Fully automated research stainer that automates staining step which ensures that microscope slides are produced with consistent, reproducible, and efficient way. Utilizes biological assay called immunohistochemistry.BOND RX model expands on the capabilities of IHC by including other assays.
Proper citation: Leica: BOND RX Stainer (RRID:SCR_025548) Copy
https://github.com/dib-lab/TheGreatGenotyper
Software workflow begins by preprocessing short-read samples of raw data to create counting colored De Bruijn graph. Graph based method for population genotyping of small and structural variants. Population genotyping workflow.
Proper citation: The Great Genoytper (RRID:SCR_025487) Copy
https://www.bio-rad.com/en-pt/product/tc20-automated-cell-counter?ID=M7FBG34VY
Automated cell counter accurately counts cells in one simple step using auto-focus technology and cell-counting algorithm. Enables accurate cell counting in less than 30 seconds.
Proper citation: Bio-Rad: TC20 Automated Cell Counter (RRID:SCR_025462) Copy
https://www.techno-path.com/product/biologs-omnilog-pm-system/
Instrument that runs Biolog's microplate metabolic arrays. Incubates and monitors 50 microplates, or 1,920 phenotypic assays simultaneously to measure physiological responses in diverse microbial cells. OmniLog PM system includes software for analysis of Biolog Phenotype MicroArray panels.
Proper citation: Technopath: Biolog OmniLog PM System (RRID:SCR_025463) Copy
Interactive web-based platform presenting global cancer statistics to inform cancer control and cancer research. Focuses on the visualization of cancer indicators using data from IARC’s Cancer Surveillance Branch (CSU), including GLOBOCAN;Cancer Incidence in Five Continents (CI5); International Incidence of Childhood Cancer (IICC); and several cancer survival benchmarking projects (SurvCan and SURVMARK).
Proper citation: Global Cancer Observatory (RRID:SCR_025451) Copy
https://polymerscreen.yale.edu
Open access web app that allows users to search for optimal condition for extraction of membrane proteins into membrane active polymers which allows for retention of native membrane environment around target protein.
Proper citation: MAP Database Guide for Membrane Protein Solubilization (RRID:SCR_025656) Copy
Publicly accessible 3D data repository where subject experts, educators, and general public can find, view, interact with, and download 3D and 2D media representing physical objects important to the world’s natural history, cultural heritage, and scientific collections. Media data are contributed by a community that includes museums, institutions, researchers, scholars, and other subject experts who use MorphoSource to archive data, share findings, and increase scholarly impact. Contributed media represent both biological objects such as fossils and representatives of living species, as well as artifacts and objects created by humans that are critical to our shared cultural heritage.
Proper citation: MorphoSource (RRID:SCR_025654) Copy
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