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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
LOCAS
 
Resource Report
Resource Website
1+ mentions
LOCAS (RRID:SCR_013064) LOCAS software resource A software to assemble short reads of next generation sequencing technologies at low coverage. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21858125 OMICS_00019, biotools:locas https://bio.tools/locas SCR_013064 SciCrunch Registry 2026-11-07 11:57:43 2
PRICE
 
Resource Report
Resource Website
100+ mentions
PRICE (RRID:SCR_013063) PRICE software resource Software for a de novo genome assembler implemented in C++. c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at San Francisco; California; USA
OMICS_01430, biotools:price https://bio.tools/price SCR_013063 SciCrunch Registry Paired-Read Iterative Contig Extension 2026-11-07 11:57:35 165
OntoQuest
 
Resource Report
Resource Website
OntoQuest (RRID:SCR_013281) OntoQuest software resource An ontology management module to perform ontology-based search over data sources. This management system permits a user to store, search and navigate any number of OWL-structured ontologies. Ontoquest may also be accessed through a variety of web services via the Neuroscience Information Framework. ontology, interoperability, owl, middleware, web service, bio.tools, bio.tools is listed by: 3DVC
is listed by: bio.tools
is listed by: Debian
is related to: NIFSTD
is related to: NIF Web Services
has parent organization: Neuroscience Information Framework
PMID:18958629 biotools:list_ontologies, biotools:ontoquest_ws, nlx_151737 https://bio.tools/list_ontologies, https://bio.tools/ontoquest_ws SCR_013281 SciCrunch Registry Ontoquest 2026-11-07 11:57:45 0
chimerascan
 
Resource Report
Resource Website
50+ mentions
chimerascan (RRID:SCR_013298) chimerascan software resource Software package that detects gene fusions in paired-end RNA sequencing (RNA-Seq) datasets. Used for detection of chimeric transcripts in high-throughput sequencing data. Gene fusion detection, paired-end RNA sequencing data, RNA sequencing data, chimeric transcripts detection, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:chimerascan, OMICS_01343 https://bio.tools/chimerascan SCR_013298 SciCrunch Registry 2026-11-07 11:57:37 53
RDXplorer
 
Resource Report
Resource Website
1+ mentions
RDXplorer (RRID:SCR_013290) RDXplorer software resource A computational tool for copy number variants (CNV) detection in whole human genome sequence data using read depth (RD) coverage. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
biotools:RDXplorer, OMICS_00349 https://bio.tools/RDXplorer SCR_013290 SciCrunch Registry 2026-11-07 11:58:05 7
GeneSigDB
 
Resource Report
Resource Website
10+ mentions
GeneSigDB (RRID:SCR_013275) GeneSigDB analysis service resource, data access protocol, data analysis service, data or information resource, data repository, database, production service resource, service resource, software resource, storage service resource, web service Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service. gene, gene signature, curated gene signature, gene expression, gene expression signature, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Computational Biology and Functional Genomics Laboratory at Harvard
Cancer Genome Research Institute ;
Dana-Farber Cancer Institute ;
Women's Cancers Program ;
Claudia Adams Barr Foundation ;
NLM 1R01 LM010129;
NCI 1U19 CA148065;
NHGRI 1P50 HG004233
PMID:22110038 biotools:genesigdb, nlx_149342 https://bio.tools/genesigdb SCR_013275 SciCrunch Registry Gene Signature Data Base, GeneSigDB - Curated Gene Signatures Database 2026-11-07 11:58:04 24
PlantNATsDB - Plant Natural Antisense Transcripts DataBase
 
Resource Report
Resource Website
1+ mentions
PlantNATsDB - Plant Natural Antisense Transcripts DataBase (RRID:SCR_013278) PlantNATsDB analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Natural Antisense Transcripts (NATs), a kind of regulatory RNAs, occur prevalently in plant genomes and play significant roles in physiological and/or pathological processes. PlantNATsDB (Plant Natural Antisense Transcripts DataBase) is a platform for annotating and discovering NATs by integrating various data sources involving approximately 2 million NAT pairs in 69 plant species. PlantNATsDB also provides an integrative, interactive and information-rich web graphical interface to display multidimensional data, and facilitate plant research community and the discovery of functional NATs. GO annotation and high-throughput small RNA sequencing data currently available were integrated to investigate the biological function of NATs. A ''''Gene Set Analysis'''' module based on GO annotation was designed to dig out the statistical significantly overrepresented GO categories from the specific NAT network. PlantNATsDB is currently the most comprehensive resource of NATs in the plant kingdom, which can serve as a reference database to investigate the regulatory function of NATs. natural antisense transcript, annotation, high-throughput, small rna sequencing, function, regulatory function, predict, sequence, small rna, blast, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
is related to: Gene Expression Omnibus
has parent organization: Zhejiang University; Zhejiang; China
National Natural Sciences Foundation of China 30971743;
National Natural Sciences Foundation of China 31050110121;
National Natural Sciences Foundation of China 31071659;
Ministry of Science and Technology of China 2009DFA32030;
Program for New Century Excellent Talents in University of China NCET-07-0740;
Huazhong Agricultural University Scientific and Technological Self-innovation Foundation 2010SC07
PMID:22058132 Free nlx_151492, biotools:plantnatsdb https://bio.tools/plantnatsdb SCR_013278 SciCrunch Registry Plant Natural Antisense Transcripts DataBase 2026-11-07 11:57:37 9
CEM
 
Resource Report
Resource Website
1+ mentions
CEM (RRID:SCR_013241) CEM software resource An algorithm to assemble transcripts and estimate their expression levels from RNA-Seq reads. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of California at Riverside; California; USA
OMICS_01271, biotools:cem https://bio.tools/cem SCR_013241 SciCrunch Registry CEM: Transcriptome Assembly and Isoform Expression Level Estimation from Biased RNA-Seq Reads 2026-11-07 11:57:37 1
BEADS
 
Resource Report
Resource Website
10+ mentions
BEADS (RRID:SCR_013229) BEADS software resource Software for a normalization scheme that corrects nucleotide composition bias, mappability variations and differential local DNA structural effects in deep sequencing data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: University of Cambridge; Cambridge; United Kingdom
PMID:21646344 OMICS_00466, biotools:beads https://bio.tools/beads SCR_013229 SciCrunch Registry BEADS: Bias Elimination Algorithm for Deep Sequencing, Bias Elimination Algorithm for Deep Sequencing 2026-11-07 11:57:44 38
Trans-ABySS
 
Resource Report
Resource Website
50+ mentions
Trans-ABySS (RRID:SCR_013322) Trans-ABySS software resource A software pipeline for analyzing ABySS-assembled contigs from shotgun transcriptome data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
OMICS_01326, biotools:trans-abyss https://bio.tools/trans-abyss/ SCR_013322 SciCrunch Registry 2026-11-07 11:57:48 72
Dali Server
 
Resource Report
Resource Website
500+ mentions
Dali Server (RRID:SCR_013433) analysis service resource, data analysis service, production service resource, service resource, software resource Network service for comparing protein structures in 3D. You submit the coordinates of a query protein structure and Dali compares them against those in the Protein Data Bank (PDB). You receive an email notification when the search has finished. In favourable cases, comparing 3D structures may reveal biologically interesting similarities that are not detectable by comparing sequences. Requests can also be submitted by e-mail to dali-server at helsinki dot fi. The body of the e-mail message must contain atomic coordinates in PDB format. If you want to know the structural neighbours of a protein already in the Protein Data Bank (PDB), you can find them in the Dali Database. If you want to superimpose two particular structures, you can do it in the pairwise DaliLite server. Academic users may download the DaliLite program for local use. Protein structure comparison server, protein structure, comparison server, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
has parent organization: University of Helsinki; Helsinki; Finland
PMID:20457744 Free, Freely available biotools:dali https://bio.tools/dali SCR_013433 SciCrunch Registry Dali 2026-11-07 11:57:47 534
ENIGMA
 
Resource Report
Resource Website
100+ mentions
ENIGMA (RRID:SCR_013400) data analysis software, data processing software, software application, software resource A software tool to extract gene expression modules from perturbational microarray data, based on the use of combinatorial statistics and graph-based clustering. The modules are further characterized by incorporating other data types, e.g. GO annotation, protein interactions and transcription factor binding information, and by suggesting regulators that might have an effect on the expression of (some of) the genes in the module. Version : ENIGMA 1.1 used GO annotation version : Aug 29th 2007 genome, gene, genetic software, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
is parent organization of: ENIGMA-DTI Pipeline
PMID:18402676 biotools:enigma, nlx_144365 https://bio.tools/enigma SCR_013400 SciCrunch Registry 2026-11-07 11:57:46 133
Pairwise Conservation Scores - An Algorithm to Identify Conserved K-mers
 
Resource Report
Resource Website
1+ mentions
Pairwise Conservation Scores - An Algorithm to Identify Conserved K-mers (RRID:SCR_013409) PCS software resource A stand-alone package to identify and analyze conserved k-mers in pairwise alignment. This program shows high performance for identifying miRNA seed binding sites in 3''-UTRs. perl, perl script, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Tsinghua University; Beijing; China
biotools:pcs, nlx_33020 https://bio.tools/pcs http://bioinfo.au.tsinghua.edu.cn/member/~gujin/pcs/ SCR_013409 SciCrunch Registry Pairwise Conservation Scores 2026-11-07 11:57:46 3
CNV-seq
 
Resource Report
Resource Website
100+ mentions
CNV-seq (RRID:SCR_013357) CNV-seq software resource A method for detecting DNA copy number variation (CNV) using high-throughput sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:cnv-seq, OMICS_00339 https://bio.tools/cnv-seq SCR_013357 SciCrunch Registry 2026-11-07 11:57:46 167
GWAMA
 
Resource Report
Resource Website
100+ mentions
GWAMA (RRID:SCR_006624) GWAMA data analysis software, data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for meta analysis of whole genome association data. meta, analysis, genome, association, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:20509871
DOI:10.1186/1471-2105-11-288
THIS RESOURCE IS NO LONGER IN SERVICE biotools:gwama, OMICS_00235 https://bio.tools/gwama, https://sources.debian.org/src/gwama/ http://www.well.ox.ac.uk/GWAMA/ SCR_006624 SciCrunch Registry Genome-Wide Association Meta Analysis 2026-11-07 11:55:57 177
casper
 
Resource Report
Resource Website
100+ mentions
casper (RRID:SCR_006613) casper software resource Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU General Public License, v2 or greater biotools:casper, OMICS_01270 https://bio.tools/casper SCR_006613 SciCrunch Registry casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads 2026-11-07 11:56:15 152
MIRIAM Resources
 
Resource Report
Resource Website
1+ mentions
MIRIAM Resources (RRID:SCR_006697) catalog, data access protocol, data or information resource, database, narrative resource, software resource, standard specification, web service A set of online services created in support of MIRIAM, a set of guidelines for the annotation and curation of computational models. The core of MIRIAM Resources is a catalogue of data types (namespaces corresponding to controlled vocabularies or databases), their URIs and the corresponding physical URLs or resources. Access to this data is made available via exports (XML) and Web Services (SOAP). MIRIAM Resources are developed and maintained under the BioModels.net initiative, and are free for use by all. MIRIAM Resources are composed of four components: a database, some Web Services, a Java library and this web application. * Database: The core of the system is a MySQL database. It allows us to store the data types (which can be controlled vocabularies or databases), their URIs and the corresponding physical URLs, and other details such as documentation and resource identifier patterns. Each entry contains a diverse set of details about the data type: official name and synonyms, root URI, pattern of identifiers, documentation, etc. Moreover, each data type can be associated with several resources (or physical locations). * Web Services: Programmatic access to the data is available via Web Services (based on Apache Axis and SOAP messages). In addition, REST-based services are currently being developed. This API allows one to not only resolve model annotations, but also to generate appropriate URIs, based upon the provision of a resource name and accession number. A list of available web services, and a WSDL are provided. A browser-based online demonstration of the Web Services is also available to try. * Java Library: A Java library is provided to access the Web Services. The documentation explains where to download it, its dependencies, and how to use it. * Web Application: A Web application, using an Apache Tomcat server, offers access to the whole data set via a Web browser. It is possible to browse by data type names as well as browse by tags. A search engine is also provided. life science, bio.tools is used by: Identifiers.org
is listed by: bio.tools
is listed by: Debian
has parent organization: European Bioinformatics Institute
PMID:22140103
PMID:18078503
Free nlx_69582, biotools:miriam https://bio.tools/miriam SCR_006697 SciCrunch Registry MIRIAM Registry 2026-11-07 11:56:16 1
Immune Epitope Database and Analysis Resource (IEDB)
 
Resource Report
Resource Website
500+ mentions
Immune Epitope Database and Analysis Resource (IEDB) (RRID:SCR_006604) IEDB analysis service resource, data analysis service, data repository, production service resource, service resource, storage service resource Repository contains antibody/B cell and T cell epitope information and epitope prediction and analysis tools. Immune epitopes are defined as molecular structures recognized by specific antigen receptors of the immune system, namely antibodies, B cell receptors, and T cell receptors. Immune epitopes from infectious diseases, excluding HIV, and immune-mediated diseases and the accompanying biological information are included. human, non-human primate, rodent, pig, cat, non-human animal, t cell, b cell, epitope, infectious disease, major histocompatibility complex, bio.tools, FASEB list is listed by: NIH Data Sharing Repositories
is listed by: Debian
is listed by: bio.tools
is affiliated with: AIRR Knowledge Commons
has parent organization: NIAID
has organization facet: La Jolla Institute for Immunology
niad PMID:39558162 open nif-0000-03017, biotools:iedb, r3d100012702 https://nextgen-tools.iedb.org/, https://doi.org/10.17616/R3X217 SCR_006604 SciCrunch Registry Immune Epitope Database and Analysis Resource, , IEDB 2026-11-07 11:55:57 622
SpliceTrap
 
Resource Report
Resource Website
10+ mentions
SpliceTrap (RRID:SCR_006728) SpliceTrap software resource A statistic tool for quantifying exon inclusion ratios in paired-end RNA-seq data, with broad applications for the study of alternative splicing. SpliceTrap approaches to exon inclusion level estimation as a Bayesian inference problem. For every exon it quantifies the extent to which it is included, skipped or subjected to size variations due to alternative 3?/5? splice sites or Intron Retention. In addition, SpliceTrap can quantify alternative splicing within a single cellular condition, with no need of a background set of reads. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
has parent organization: Cold Spring Harbor Laboratory
PMID:21896509 biotools:splicetrap, OMICS_01292 https://bio.tools/splicetrap SCR_006728 SciCrunch Registry 2026-11-07 11:56:01 16
BEDTools
 
Resource Report
Resource Website
10000+ mentions
BEDTools (RRID:SCR_006646) BEDTools software resource A powerful toolset for genome arithmetic allowing one to address common genomics tasks such as finding feature overlaps and computing coverage. Bedtools allows one to intersect, merge, count, complement, and shuffle genomic intervals from multiple files in widely-used genomic file formats such as BAM, BED, GFF/GTF, VCF. While each individual tool is designed to do a relatively simple task (e.g., intersect two interval files), quite sophisticated analyses can be conducted by combining multiple bedtools operations on the UNIX command line. genomics, bed, sam, bam, overlap, sequencing, intersect, coverage, gff, vcf, bedgraph, interval, genome arithmetic, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Hydra
is related to: pybedtools
is required by: SL-quant
PMID:20110278
DOI:10.1093/bioinformatics/btq033
GNU General Public License, v2, Acknowledgement requested OMICS_01159, biotools:bedtools https://code.google.com/p/bedtools/, https://bio.tools/bedtools, https://sources.debian.org/src/bedtools/ SCR_006646 SciCrunch Registry bedtools - a swiss army knife for genome arithmetic, bedtools: a flexible suite of utilities for comparing genomic features 2026-11-07 11:55:58 11365

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