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https://cancer.iu.edu/research/shared-facilities/pmtc/ivt.html

Core supports research and development of safe and more efficacious drug treatment. Provides cost-effective and comprehensive services including, but not limited to, on-site breeding facilities as well as in vivo pharmacology models to facilitate development and testing of novel pharmacological and cellular therapies.

Proper citation: Indiana University School of Medicine In Vivo Therapeutics Core Facility (RRID:SCR_025569) Copy   

•   Source: SciCrunch Registry

https://www.uidaho.edu/cals/nutrition-womens-health

Core facility that provides expertise and instruments/equipment to promote research in nutrition and/or women’s health by leveraging resources from new and existing institutional programs and fostering collaborations across disciplines. Consists of hub laboratory suite with wet bench laboratory, body composition assessment and resting metabolic rate laboratories, computer laboratory, metabolic kitchen, and network of partnering laboratories distributed across the UI and the state of Idaho.

Proper citation: University of Idaho UI COBRE Nutrition Analytics Core Facility (RRID:SCR_025661) Copy   

•   Source: SciCrunch Registry

https://med.uc.edu/research/core/Index/208/Facility/

Integrates technology in single-particle cryogenic electron microscopy. Thermo Scientific Talos L120C Transmission Electron Microscope is available for visualizing nanoparticles, negatively stained proteins or conventional biological samples. It can be operated at 80kV or 120kV. Thermo Scientific Glacios 200 kV cryogenic TEM is equipped with both Ceta-16M camera and TFS Falcon 4 direct electron detector, in addition to Selectris Energy Filter. This system is able to generate images for atomic resolution structures for single particle analysis projects. Glacios also includes software for micro-Electron Diffraction data set collection. Available services include Training and access to the Mark IV Vitrobot plunge freezer,Training and access to the Talos L120C TEM system, Training and access to the Glacios 200 kV cryogenic TEM system, Assisted TEM analysis by CASB personnel.

Proper citation: University of Cincinnati Center for Advanced Structural Biology Core Facility (RRID:SCR_025796) Copy   

•   Source: SciCrunch Registry

https://med.uc.edu/research/core/Index/36/Facility/

Offers access to microscopes and flow cytometry equipment for researchers. Available services include Upright and inverted widefield microscopy, Confocal Microscopy (Zeiss LSM 710), Super-Resolution Microscopy (Nikon SIMe), Live Cell Microscopy (Incucylte), Flow Cytometry (BD LSR Fortessa), Cell Sorting (BD Aria III).

Proper citation: University of Cincinnati Advanced Cell Analysis Service Center Core Facility (RRID:SCR_025797) Copy   

•   Source: SciCrunch Registry

https://omrf.org/research-faculty/core-facilities/clinical-genomics-center/

Offers high-throughput sequencing and genotyping services utilizing cutting edge Illumina and Xoford Nanopore systems. Sequencing facility in Oklahoma. Equipped with an Illumina NovaSeq 6000, Illumina NextSeq 2000, Illumina MiSeq, Illumina iSeq, Oxford Nanopore PromethION 2, and Oxford Nanopore MinION,Illumina iScan and Autoloader for extremely-high throughput genotyping projects. Core can perform all aspects of NGS, ranging from whole genome sequencing to single-cell transcriptomics.

Proper citation: Oklahoma Medical Research Foundation OMRF Clinical Genomics Center Core Facility (RRID:SCR_025894) Copy   

•   Source: SciCrunch Registry

https://med.uc.edu/research/core/Index/44/Facility/

Core is equipped with protein separation and mass spectrometry equipment as well as trained personnel to perform comparative analyses of complex protein mixtures and to identify differentially-expressed proteins. Offers guidance and consultation.

Proper citation: University of Cincinnati Proteomics Laboratory Core Facility (RRID:SCR_025895) Copy   

•   Source: SciCrunch Registry

https://mct.stanford.edu/

Core provides nondestructive, high-resolution images of internal structure of variety of natural and engineered materials using X-ray micro-computed tomography. microCT can resolve structures on micrometer scale.

Proper citation: Stanford University MicroCT Core Facility (RRID:SCR_025800) Copy   

•   Source: SciCrunch Registry

https://minpetlab.stanford.edu/

Core offers qualitative and quantitative characterization of Earth materials by providing optical microscopes for high-resolution imaging of loose materials and thin sections, computational resources for image processing, and bench space for light processing of samples before or after use of the Sample Preparation Lab.

Proper citation: Stanford University Mineralogy and Petrology Lab Core Facility (RRID:SCR_025801) Copy   

•   Source: SciCrunch Registry

https://www.cryo-em.uni-freiburg.de/

Core offers services related to cryo electron microscopy. Services include grid preparation, screening and data collection, as well as user training.

Proper citation: University of Freiburg Cryo-Electron Microscopy Core Facility (RRID:SCR_025860) Copy   

•   Source: SciCrunch Registry

https://www.petermac.org/research/research-technologies/bioinformatics

Provides services for data analysis, pipeline management, and artificial intelligence research and operations. Data types analysed by the core include whole-genome and whole-exome sequencing, targeted re-sequencing, radiological images, RNA-sequencing, single-cell RNA sequencing, ChIP-sequencing, NanoString and various types of microarray data. Core also develops and maintains software infrastructure required for bioinformatics processing, including pipelines and cloud provision systems.

Proper citation: Peter MacCallum Cancer Centre Bioinformatics Core Facility (RRID:SCR_025901) Copy   

•   Source: SciCrunch Registry

https://med.uth.edu/ibp/cam/

Microscopy facility serving Texas Medical Center. Facilitates utilization of advanced light microscopy techniques and quantitative image analysis to advance research programs of McGovern Medical School, UTHealth, and the greater Texas Medical Center. Fluorescence microscopy and image analysis core.

Proper citation: UTHealth Houston Center for Advanced Microscopy Core Facility (RRID:SCR_025962) Copy   

•   Source: SciCrunch Registry

https://behavior.hms.harvard.edu/

Core offers mouse behavioral equipment and assays to test motor, cognitive, and affective behaviors. Trained users have access to behavioral testing rooms and procedure room. MBC staff offers consultation, training, and guidance in execution and interpretation of assays.

Proper citation: Harvard Medical School Mouse Behavior Core Facility (RRID:SCR_025842) Copy   

•   Source: SciCrunch Registry

https://www.pedsresearch.org/research/cores/biostatistics-core/overview/

Offers statistical expertise and services. Provides assistance and collaboration in study design, grant applications, protocol development, data analysis, publication preparation, and statistical education.

Proper citation: Emory University Pediatric Biostatistics Core Facility (RRID:SCR_025834) Copy   

•   Source: SciCrunch Registry

https://www.pedsresearch.org/research/cores/animal-physiology-core/overview/

Centralized core specializing in survival surgery, technical procedures, and ultrasound imaging for rats and mice and assistance for surgical procedures in other species.

Proper citation: Emory University Animal Physiology Core Facility (RRID:SCR_025835) Copy   

•   Source: SciCrunch Registry

https://geiselmed.dartmouth.edu/msp/

Core offers quantitative and qualitative proteomics services using LC-MS/MS technologies. Servies include sample preparation from harvested cell pellets, elutions post-enrichment or purification, or gel bands through data acquisition, quantification, and statistical analysis.

Proper citation: Dartmouth Geisel School of Medicine Biological Mass Spectrometry and Proteomics Shared Resource Core Facility (RRID:SCR_026076) Copy   

•   Source: SciCrunch Registry

https://www.goodmancancer.ca/en/histology-innovation-platform

Core provides expertise, cutting edge technology, and efficient workflows in histological processing, analysis and interpretation.

Proper citation: McGill University Goodman Cancer Institute Histology Innovation Platform Core Facility (RRID:SCR_026126) Copy   

•   Source: SciCrunch Registry

https://johnshopkins.ilab.agilent.com/service_center/show_external/3819?name=reference-histology

Provides histology services for Autopsy, Cytology, Renal Pathology and Medical Archives Office within Department of Pathology. In conjunction with Pathology Send Out and Archives divisions, provides histology for clinical trial requests, scientific study or interest involving pathology materials. Services include: Complete routine paraffin histology services, including processing and sectioning; Special stains, including but not limited to carbohydrates, connective tissue, fats, lipids, microorganisms, nuclear elements, pigments, silver techniques; Immunopathology slide preparation techniques;DNA slide preparations; Frozen tissue sections; Oversized tissue processing and sectioning ;Histopathology teaching sets; Customized procedures.Services are provided for both human and animal tissue samples.

Proper citation: Johns Hopkins Reference Histology Core Facility (RRID:SCR_025986) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/confocal-microscopy/index.html

Facility houses imaging technologies ranging from super resolution (~ 0.120 um to 0.020 um) to microscopic (~ 0.300 um) to mesoscopic (~ 1 um) biomedical imaging. Imaging specialists provide training and/or actively assist researchers collecting images across imaging instrumentation. Instrumentation includes Zeiss ELYRA PS.1 is inverted microscope for super resolution (SR) structured illumination microscopy (SIM) and single molecule localization microscopy (SMLM) including, PhotoActivated Localization Microscopy (PALM) using photo switchable/convertible fluorescent proteins, Total Internal Reflection Fluorescence (TIRF) and STochastic Optical Reconstruction Microscopy (STORM);Zeiss 800 CLSM with Airyscan is an inverted microscope dramatically increasing conventional confocal image resolution to ~180 nm using Airyscan technology; Zeiss 710 LSM is inverted microscope supporting most basic imaging applications, multi channel and spectral, co localization, live cell, 3D, and time series imaging; Zeiss Celldiscoverer 7 is widefield imaging system for automated, time lapse imaging of live samples; Zeiss Axioscan 7 is high performance whole slide scanning system for fluorescence, brightfield, and polarization imaging;Miltenyi Biotec Ultramicroscope II Light Sheet fluorescence microscope (LSFM) extends fluorescent imaging into true 3D, large scale volumetric imaging of intact tissues, organs, and small organisms. AMCF also houses several high-end data analysis workstations with premier image analysis software including HALO (Indica Labs) and IMARIS (Oxford Instruments) facilitating data rendering, analyses, and presentation options.

Proper citation: University of Nebraska Medical Center Advanced Microscopy Core Facility (RRID:SCR_022467) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/animal

Offers behavioral phenotyping of rodent models as well as characterizing nervous system function in mouse and rat models through behavioral assays.

Proper citation: Cincinnati Children's Hospital Animal Behavior Core Facility (RRID:SCR_022621) Copy   

•   Source: SciCrunch Registry

http://www.ohri.ca/bioinformatics

Core of University of Ottawa and Ottawa Hospital Research Institute. Provides advice on bioinformatics research design, conduct bioinformatics analysis, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters and methodological text). Areas of expertise include:Analysis of high throughput sequencing data; single cell (Chromium 10x), RNA-seq (including small RNA), ChIP-seq, ATAC-seq, Hi-C.Large scale analysis integrating multiple data types.Helps to arrange for analysis of your biological samples with local core facilities such as StemCore, Proteomics Resource Center, or OHRI Mass Spectrometry Core Facility. Provides yearly training courses in RNA-seq analysis and Bioinformatics analysis using R as well as individual training and analysis support on request.

Proper citation: University of Ottawa Bioinformatics Core Facility (RRID:SCR_022466) Copy   

•   Source: SciCrunch Registry