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http://eagle-i.itmat.upenn.edu/i/00000138-b423-f2be-9cd7-d7e280000000

The High-Performance Computing (HPC) Facility provides the hardware and staff to support bioinformatics and biocomputational research. The central component of this facility is a large cluster of 64 high-speed compute nodes, along with approximately 900 terabyte of shared disk storage and nearly 1.8 petabytes of archival storage.

Proper citation: University of Pennsylvania High-performance Computing (RRID:SCR_010016) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000142-13cf-cf71-91c7-0c6080000000

In the Interventional Radiology Catheter Lab minimally invasive procedures are performed via fluoroscopy, ultrasound and endoscopy. Percutaneous vein and arterial access is performed via ultrasound-guided technique. Surgeons are then able to guide catheters, ballon dilation, and other small instrumentation through the blood vessels. Procedures that have been performed in the lab are: * Angiography * Aneurysm creation * Balloon angioplasty * Embolization (coil, glue, embospheres) * Inferior vena Cava (IVC) filter placement & retrieval * Selective arterial catheterization * Stent placement (renal, gastric, iliac) * Peroral gastroenteric anastomosis This lab has capabilities for full surgical and anesthesia protocols and full fluoroscopy imaging. Included in the lab are a small office space, an LCD monitor and computer for the fluoroscopy unit, eye wash station and a surgeon scrub sink.

Proper citation: Penn Interventional Radiology Animal Catheter Lab (RRID:SCR_010019) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-b6a6-e595-9dbb-bb2180000000

Core facility that provides the following services: NBIC instrumentation training, Scanning probe measurement service. The NBIC serves as an incubator for new probes of nanostructure behavior and associated instrumentation development. It is equipped with a suite of scanning probes, opto-electronic/transport tools, and optical probes that are so recently developed as not to be available on commercial instruments. The environment facilitates the development and refinement of new probe-based techniques.

Proper citation: Penn NBIC Probe Facility (RRID:SCR_010023) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-baad-3af2-9cd7-d7e280000000

Core facility that provides the following services: Behavioral testing training, Behavioral testing consultation service, Neurobehavior Testing Core access, Evaluation of anxiety behavior, Evaluation of circadian activity and rest/activity patterns, Measurement of sleep/wake patterns, Video image analysis of behavioral assays, Tissue harvest and histology prep service, Customized behavior batteries. The Neurobehavior Testing Core provides core facilities and services to test mice in state of the art assays of simple and complex behaviors, including the assessment of circadian rhythms and sleep, learning and memory, motor and sensory function, as well as behavioral assays relevant to translational studies of neurological, neurodevelopmental and psychiatric disorders. The core offers comprehensive behavior phenotyping of your mice or can train your lab personnel to perform the tests in the facility. In addition, we provide consultation on study design including appropriate tests, mouse line/strain, numbers of animals, control groups and breeding strategies. The core will also provide consultation regarding ULAR, IACUC and other regulatory issues. Assistance with data analysis is also available. The behavior apparatus available in the core includes: running wheels and beam splitters to measure circadian activity and rest/activity patterns as well as EEG/EMG recording chambers to measure sleep/wake states. Motor function is assessed using open field activity monitors and Rotarod. Apparatus to measure anxiety-like behavior including zero maze, light/dark chamber, passive/active avoidance chambers and hole poke arenas are also available. Extensive assessment of cognition, learning and memory is conducted with Morris water maze, radial arm maze, 5 choice serial reaction time test and object recognition tests. Tests of behaviors associated with depression (forced swim), schizophrenia (startle/PPI), social interaction (choice and social memory), and drug addiction (conditioned place preference) are also available. Tests of general health and responsiveness are also performed, as these are critical for the evaluation of complex behavior. Support for the core is provided by the Comprehensive Neuroscience Center, the Institute for Translational Medicine and Therapeutics, the Center for Sleep and Circadian Neurobiology and the Perelman School of Medicine.

Proper citation: Penn Neurobehavior Testing Core (RRID:SCR_010024) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012d-4d11-7063-27fd-1f1480000000

The Harold L. Lyon Arboretum is a leader in the fields of conservation biology, Hawaiian ethnobotany and horticulture. On its 194 acres, Lyon Arboretum maintains a world renowned collection of more than 5,000 tropical plant species; supports Hawaii''s horticultural and agriculture industries; and works to preserve and restore Hawaii''s tropical forests. It is an active research facility and academic resource offering a wide range of programs to local and international communities including an innovative and ground-breaking tissue culture program for propagation of endangered native Hawaiian plants. With an abundant average rainfall of 165 inches, this tropical rainforest setting is an ideal location for growing an enormous diversity of plants. The plant collection features heliconias, gingers, aroids, bromeliads, native Hawaiian plants, and one of the largest palm collections found in a botanical garden.

Proper citation: UH Manoa Lyon Arboretum (RRID:SCR_010102) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-7f26-419c-2f73-b43980000000

Core facility that provides the following services: Tissue embedding service, Tissue sectioning service, Immunohistochemistry service, In situ hybridization service, DNA extraction service, Tissue microarray slides service, Tissue microarrays service, Genotyping service. The Pathology Shared resource capitalizes on the existing infrastructure of the Center''s tissue repository. The Repository currently consists of fixed, paraffin-embedded tissue specimens from hospitals and laboratories statewide. The purpose of the repository is to provide tissue specimens to Center members and other investigators for research purposes. A priority is placed on the provision of specimens for population-based research and peer-reviewed, extramurally funded projects. The repository is a part of the Residual Tissue Repository Program of the NCI SEER program (http://seer.cancer.gov/biospecimen/).

Proper citation: UH Manoa Pathology Shared Resources (RRID:SCR_010106) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2510-e7b9-c99c-aef680000000

The Biostatistics and Data Management Facility (BDMF) was established with a primary mission to provide a range of customized statistical and database management services for RCMI researchers. Realizing a need for a consolidated and integrated statistical resources for biomedical researchers and clinicians at the John A. Burns School of Medicine, the BDMF has rapidly extended services to other programs and groups, including the Asia-Pacific Institute of Tropical Medicine and Infectious Diseases (APITMID), Pacific Biosciences Research Center (PBRC), Excellence in Partnerships for Community Outreach, Research on Health Disparities, and Training (EXPORT), Specialized Neuroscience Research Program (SNRP-I/II), Center of Biomedical Research Excellence (COBRE), Centers of Clinical Research Excellence (CCRE), Clinical Research Education and Career Development (CRECD), RCMI clinical Research Infrastructure Initiative (RCRII), and IDeA Networks of Biomedical Research Excellence (INBRE). The overall mission of the BDMF is to provide quantitative resources essential for investigators to conduct methodologically rigorous medical research in a timely, cost-effective manner. (http://www5.pbrc.hawaii.edu/bdmf/index.html)

Proper citation: UH Manoa RCMI Biostatistics and Data Management Facility (RRID:SCR_010107) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-5807-c99c-aef680000000

Core facility provides the following services: DNA sequencing service, DNA fragment sizing and genotyping service, Real-time PCR analysis, DNA microarray analysis service, Protein sequencing service. The Greenwood Molecular Biology Facility is a primary research infrastructure operated by the Biotechnology Program of the Pacific Biosciences Research Center. Core serves the biomedical and molecular biology research and educational programs of the University and its associated institutions.

Proper citation: University of Hawaii at Manoa Greenwood Molecular Biology Facility (RRID:SCR_010108) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-99ef-06c2-9c7f80000000

Core facility that provides the following services: Training and advice for general imaging techniques, Histology processing service, Hematoxylin and eosin staining service, Training and advice for general histology techniques. This lab provides routine histology processing, specialized histochemical and immunohistological techniques, and access to several microscopic platforms. The core also provides technical assistance, training, and consultation in histological and imaging techniques to investigators throughout the University on a cost-recovery basis.

Proper citation: UH Manoa RCMI Histology and Imaging Core Facility (RRID:SCR_010109) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-c5d0-1c3d-a53f-a15a80000000

Core facility that provides the following services: Protein separation service, 2D gel production, Analysis of protein distribution of 2D gel, Standardized imaging of 2D gel, Mass spectrometry analysis service, Desalting, Trypsin Digestion. The mission of the UCC Biomedical Proteomic Facility is to accelerate discovery by giving UCC investigators access to cutting edge mass spectrometry are rapidly advancing and requires considerable technical expertise and expensive equipments. To keep UCC scientists competitive, new technologies will be incorporated into the facility as soon as possible to meet the needs. The facility is open to all investigators on collaboration or a fee-for-service basis. User fees will be adjusted depending on demand and to keep costs competitive.

Proper citation: UCC Biomedical Proteomic Facility (RRID:SCR_010073) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-aaee-9c0e-a272-8ee780000000

Core facility that provides the following services: HIV and HCV viral load extraction, Amplification and detection of HCV and HIV viral load, HIV-1 and HCV drug resistance genotyping, Neurotoxicity and neuroprotection assays, PBMC antiviral assay, MAGI antiviral assay, HIV-1 Tat inhibition assay, HIV p24 measurement service, Cytokine/Chemokine measurement, Hormone measurement, NF-kB expression induction assay, Detection of TH1, TH2, Treg, and TH17 cytokine profiles in T lymphocytes subsets, Immunophenotyping, intracellular cytokines/chemokines and apoptosis assay service, B and T cell immune activation, function, proliferation and differentiation assays, Macrophage function assay, Cell viability, cell proliferation and cytotoxicity, Cell cycle analysis, Inflammation and oxidative stress Calcium mobilization, kinase activation, and signal transduction, Gene expression service, Apoptosis test, In vivo/in vitro cytotoxicity measurement, Plaque and colony formation counting, Inflammation antibody array service, Apoptosis antibody array service, Angiogenesis antibody array, Protein and gene expression study, Standardized imaging of 2D gel. The laboratory supports research in the areas of HIV/AIDS and substances of abuse. Specialized facilities are made available to researchers for scientific studies in fields of immunology, drugs of abuse, HIV/AIDS and related infectious diseases. The core lab provides researchers with assays for nucleic acids detection, virus genotyping, flow cytometric phenotyping, lymphocyte proliferation, cytotoxic and non-cytotoxic activity, cytokine and chemokine determinations, and drugs of abuse quantification.

Proper citation: UCC HIV and Substance of Abuse Laboratory Core (RRID:SCR_010076) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-cb34-a797-a53f-a15a80000000

Core facility that provides the following services: Immunocytochemistry service. The immunocytochemistry laboratory specializes in the qualitative identification and localization of cells bearing selective markers by employing specific antibodies to these molecules.

Proper citation: UCC Immunocytochemistry Laboratory (RRID:SCR_010077) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-ca9b-b63c-a53f-a15a80000000

Core facility that provides the following services: Qualitative measure of neuronal death, Computerized image analysis. The goal of the facility is to assist UCC investigators in the use of cultured neurons, glias and organotypic cultures. The cultures are used for patch clamping after in vitro treatments with drugs of addiction or inhibitors and for in vitro models of neurodegenerative diseases. The core facility consists of a coordinator and a technician. Neuronal cultures are prepared from fetal cortex, hippocampus or astrocytes from cerebral cortex.

Proper citation: UCC Neuronal Glia Culture Facility (RRID:SCR_010078) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-d046-71cb-a53f-a15a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. The facility offers microscope-based systems that allow the assessment of cellular responses, such as calcium signaling with fast temporal resolution. The facility offers 1) Confocal imaging services; 2) Brightfield, darkfield, phase contrast, Nomarski and epi-fluorescence imaging; 3) High spatial and temporal resolution imaging, 4) Collection of serial sections (Deconvolution capabilities) and 5) Morphometric analysis.

Proper citation: UCC Optical Imaging Facility (RRID:SCR_010079) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012f-0445-ea9e-1247-b2dc80000000

Core facility that provides the following services: MRI image analysis service, MRI image processing service.

Proper citation: UH Manoa Hawaii Center for AIDS Imaging Analysis Core (RRID:SCR_010083) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2510-69a9-c99c-aef680000000

A 2000 square foot BSL-3 facility located at the University of Hawaii, JABSOM.

Proper citation: UH Manoa BSL-3 Containment Facility (RRID:SCR_010086) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-469c-06c2-9c7f80000000

Core facility that provides the following services: Scanning electron microscopy service, Conventional and energy-filtering transmission electron microscopy service, Laser scanning confocal microscopy service, Fluorescence microscopy service, Laser microdissection and laser tweezing service. The Biological Electron Microscope Facility (BEMF) at the University of Hawai''i is a multi-user/service facility, administered by the Pacific Biosciences Research Center (PBRC). The mission of the BEMF is to provide biological-biomedical researchers with state-of-the-art instrumentation, training and services for high-resolution scanning electron microscopy, conventional and energy-filtering transmission electron microscopy, optical, fluorescence, and laser scanning confocal microscopy, and image analysis on a recharge basis. The facility receives partial support from the Pacific Biosciences Research Center and the UH Manoa Chancellor''s Office. Includes the Richard Allen Image Collection, a unique set of images taken with electron microscopes (http://www5.pbrc.hawaii.edu/allen/).

Proper citation: UH Manoa Biological Electron Microscope Facility (RRID:SCR_010087) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-b257-d364-2f73-b43980000000

The Biostatistics Shared Resource (BSR) provides statistical consultation and support to the research enterprise of the University of Hawai?i Cancer Center. The primary goal of the resource is to improve the quality of the research through sound statistical principles. The resource was established in 1995 and provides access to statistical support to all Center members on all aspects of research. The BSR provides short-term as well as long-term support for research projects. Support is provided to scientists in epidemiology, health behavior and quality of life research, and molecular and clinical oncology. The members of the Shared Resource often serve as co-investigators on epidemiology and cancer prevention and control projects. Consultation is available in the following areas: design, data collection, data analysis, statistical programming, interpretation and dissemination of results, and protocol review. The members of the resource have contributed to the publication of many peer-reviewed manuscripts from Center research projects. In addition, the statisticians work on methodological issues important to the research ongoing at UH Cancer Center. One area of interest is measurement error models that correct for bias in model parameter estimates when the exposure variable is measured with error. The role of dietary intake and sunlight exposure in cancer etiology are of interest at the Center, and these variables are measured with error. Another interest is in how susceptibility genes affect cancer risk, in combination with exposure data. Therefore, statistical techniques for the investigation of genes and lifestyle-gene interactions in cancer models are also studied.

Proper citation: UH Manoa Biostatistics Shared Resources (RRID:SCR_010088) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-0387-c99c-aef680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core provides access to high speed computer hardware and bioinformatics consultation. Research at the facility includes studying of evolutionary change in emergent dengue viruses associated with increasingly severe epidemics and confirm the impact of these changes in experimental models.

Proper citation: University of Hawaii at Manoa Centers of Biomedical Research Excellence Bioinformatics Core Facility (RRID:SCR_010089) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-e488-f75c-a272-8ee780000000

Core facility that provides the following services: Nucleic acid sequencing service, Real-Time PCR services, Cell culture service, Protein quantitation assay, Nucleic acid estimation service, Fusion protein purification and expression service, Transfection service, Site-directed mutagenesis service, Primer design service, Gel electrophoresis service, Polymerase chain reaction service. The Protein and Nucleic Acid Core Facility (PNACF) aids in the transition from classical to molecular analysis of the problems being addressed by faculty members. PNACF focuses on faculty training, seminars, training on specialized molecular biology techniques, protein expression and protein purification and characterization.

Proper citation: UCC Protein and Nucleic Acid Core Facility (RRID:SCR_010080) Copy   

•   Source: SciCrunch Registry