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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
ChIPsim
 
Resource Report
Resource Website
1+ mentions
ChIPsim (RRID:SCR_001293) ChIPsim software resource Software package providing a general framework for the simulation of ChIP-seq data. Although currently focused on nucleosome positioning the package is designed to support different types of experiments. chip-seq, infrastructure, simulation is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 or newer OMICS_02042 SCR_001293 ChIPsim - Simulation of ChIP-seq experiments 2026-08-01 12:01:46 1
methyAnalysis
 
Resource Report
Resource Website
1+ mentions
methyAnalysis (RRID:SCR_001290) methyAnalysis software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for DNA methylation data analysis and visualization. A new class is defined to keep the chromosome location information together with the data. The current version of the package mainly focuses on analyzing the Illumina Infinium methylation array data, but most methods can be generalized to other methylation array or sequencing data. dna methylation, microarray, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:21159174 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02046 SCR_001290 methyAnalysis - DNA methylation data analysis and visualization 2026-08-01 12:01:46 9
les
 
Resource Report
Resource Website
les (RRID:SCR_001291) les software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package that estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip, or DNA modification analysis. The package provides a universal framework suitable for identifying differential effects in tiling microarray data sets, and is independent of the underlying statistics at the level of single probes. loci of enhanced significance, tiling microarray, tiling, microarray, chip-chip, dna modification, probe, dna methylation, differential expression, microarray, transcription, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
THIS RESOURCE IS NO LONGER IN SERVICE biotools:les, OMICS_02045 https://bioconductor.org/packages/les/, https://bio.tools/les SCR_001291 les package: Identifying Differential Effects in Tiling Microarray Data, Loci of Enhanced Significance 2026-08-01 12:01:37 0
beadarraySNP
 
Resource Report
Resource Website
beadarraySNP (RRID:SCR_001281) beadarraySNP software resource Software package for importing data from Illumina SNP experiments and performing copy number calculations and reports. copy number variation, data import, genetic variability, preprocessing, snp, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02056 http://www.bioconductor.org/packages/devel/bioc/html/beadarraySNP.html SCR_001281 beadarraySNP - Normalization and reporting of Illumina SNP bead arrays 2026-08-01 12:01:45 0
RCASPAR
 
Resource Report
Resource Website
RCASPAR (RRID:SCR_001253) RCASPAR software resource Software package for survival time prediction based on a piecewise baseline hazard Cox regression model. It is meant to help predict survival times in the presence of high-dimensional explanatory covariates. gene expression, genetics, proteomics, visualization, acgh is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02087 SCR_001253 2026-08-01 12:01:36 0
CNVtools
 
Resource Report
Resource Website
10+ mentions
CNVtools (RRID:SCR_001250) CNVtools software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package to facilitate the testing of Copy Number Variant data for genetic association, typically in case-control studies. genetic variability, copy number variant, genetic association is listed by: OMICtools
has parent organization: Bioconductor
PMID:18776912 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02090 SCR_001250 CNVtools - A package to test genetic association with CNV data 2026-08-01 12:01:35 12
multtest
 
Resource Report
Resource Website
10+ mentions
multtest (RRID:SCR_001255) multtest software resource Software package for non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments. differential expression, microarray, multiple comparison, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:multtest, OMICS_02085 https://bio.tools/multtest SCR_001255 multtest - Resampling-based multiple hypothesis testing 2026-08-01 12:01:44 35
ITALICS
 
Resource Report
Resource Website
ITALICS (RRID:SCR_001274) ITALICS software resource Software package to normalize of Affymetrix GeneChip Human Mapping 100K and 500K set. affymetrix, copy number variation, microarray is listed by: OMICtools
has parent organization: Bioconductor
PMID:18252739 Free, Available for download, Freely available OMICS_02064 SCR_001274 2026-08-01 12:01:45 0
mBPCR
 
Resource Report
Resource Website
mBPCR (RRID:SCR_001273) mBPCR software resource Software package that estimates the DNA copy number profile to detect regions with copy number changes. copy number variation, microarray, snp, acgh is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02065 SCR_001273 mBPCR - Bayesian Piecewise Constant Regression for DNA copy number estimation 2026-08-01 12:01:26 0
CGHregions
 
Resource Report
Resource Website
1+ mentions
CGHregions (RRID:SCR_001278) CGHregions software resource Software package for dimension Reduction for Array CGH Data with Minimal Information Loss. copy number variation, microarray, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:19455235 Free, Available for download, Freely available OMICS_02058 SCR_001278 CGHregions - Dimension Reduction for Array CGH Data with Minimal Information Loss 2026-08-01 12:01:45 4
quantsmooth
 
Resource Report
Resource Website
1+ mentions
quantsmooth (RRID:SCR_001271) quantsmooth software resource Software package for quantile smoothing and genomic visualization of array data. copy number variation, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:15572474 Free, Available for download, Freely available OMICS_02067, BioTools:quantsmooth, biotools:quantsmooth https://bio.tools/quantsmooth, https://bio.tools/quantsmooth, https://bio.tools/quantsmooth SCR_001271 2026-08-01 12:01:45 1
SNPchip
 
Resource Report
Resource Website
10+ mentions
SNPchip (RRID:SCR_001269) SNPchip software resource Software package that contains classes and methods useful for storing, visualizing and analyzing high density SNP data. Originally developed from the SNPscan web-tool, SNPchip utilizes S4 classes and extends other open source R tools available at Bioconductor, including the R packages Biobase and oligo. This has numerous advantages, including the ability to build statistical models for SNP-level data that operate on instances of the class, and to communicate with other R packages that add additional functionality. dna copy number, snp, genetic variability, visualization, high throughput, snp chip, microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:17204461 Free, Available for download, Freely available OMICS_02069, biotools:snpchip https://bio.tools/snpchip SCR_001269 2026-08-01 12:01:36 13
VegaMC
 
Resource Report
Resource Website
1+ mentions
VegaMC (RRID:SCR_001267) VegaMC software resource Software package that enables the detection of driver chromosomal imbalances including loss of heterozygosity (LOH) from array comparative genomic hybridization (aCGH) data. It performs a joint segmentation of a dataset and uses a statistical framework to distinguish between driver and passenger mutation. VegaMC has been implemented so that it can be immediately integrated with the output produced by PennCNV tool. In addition, it produces in output two web pages that allows a rapid navigation between both the detected regions and the altered genes. In the web page that summarizes the altered genes, the link to the respective Ensembl gene web page is reported. copy number variation, acgh, chromosomal imbalance is listed by: OMICtools
is related to: PennCNV
has parent organization: Bioconductor
Cancer PMID:22815357 Free, Available for download, Freely available OMICS_02071 SCR_001267 VegaMC: A Package Implementing a Variational Piecewise Smooth Model for Identification of Driver Chromosomal Imbalances in Cancer 2026-08-01 12:01:26 1
VanillaICE
 
Resource Report
Resource Website
1+ mentions
VanillaICE (RRID:SCR_001268) VanillaICE software resource Software package using Hidden Markov Models for characterizing chromosomal alterations in high throughput SNP arrays. statistics, dna copy number, snp, genetic variability, visualization, high throughput, snp chip, microarray is listed by: OMICtools
has parent organization: Bioconductor
has parent organization: Johns Hopkins Bloomberg School of Public Health; Maryland; USA
PMID:19609370 GNU General Public License, v2 or newer OMICS_02070 http://www.biostat.jhsph.edu/~rscharpf/software/index.html SCR_001268 vanilla-ice 2026-08-01 12:01:45 3
sRAP
 
Resource Report
Resource Website
10+ mentions
sRAP (RRID:SCR_001297) sRAP software resource Software package that provides a pipeline for gene expression analysis (primarily for RNA-Seq data). The normalization function is specific for RNA-Seq analysis, but all other functions (Quality Control Figures, Differential Expression and Visualization, and Functional Enrichment via BD-Func) will work with any type of gene expression data. gene expression, differential expression, go, gene set enrichment, microarray, preprocessing, quality control, rna-seq, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02038 http://www.bioconductor.org/packages/release/bioc/html/sRAP.html SCR_001297 Simplified RNA-Seq Analysis 2026-08-01 12:01:37 15
SCAN.UPC
 
Resource Report
Resource Website
10+ mentions
SCAN.UPC (RRID:SCR_001334) SCAN.UPC software resource A microarray normalization software (SCAN) to facilitate personalized-medicine workflows with an extension (UPC) that estimates whether a given gene/transcript is active above background levels in a given sample. Rather than processing microarray samples as groups, which can introduce biases and present logistical challenges, SCAN normalizes each sample individually by modeling and removing probe- and array-specific background noise using only data from within each array. SCAN can be applied to one-channel (e.g., Affymetrix) or two-channel (e.g., Agilent) microarrays. The UPC method can be applied to one-channel or two-channel microarrays as well as to RNA-Seq read counts. Because UPC values are represented on the same scale and have an identical interpretation for each platform, they can be used for cross-platform data integration. A microarray, one channel, preprocessing, rna-seq, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02006 SCR_001334 Single-channel array normalization (SCAN) and Universal exPression Codes (UPC), Single-channel array normalization and Universal exPression Codes 2026-08-01 12:01:28 11
SNM
 
Resource Report
Resource Website
1+ mentions
SNM (RRID:SCR_001299) SNM software resource Software package that uses a modeling strategy especially designed for normalizing high-throughput genomic data. The premise is that your data is a function of study-specific variables which are either biological variables that represent the target of the statistical analysis, or adjustment variables that represent factors arising from the experimental or biological setting the data is drawn from. The SNM approach aims to simultaneously model all study-specific variables in order to more accurately characterize the biological or clinical variables of interest. differential expression, exon array, gene expression, microarray, multi channel, multiple comparison, one channel, preprocessing, quality control, transcription, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02036 SCR_001299 Supervised Normalization of Microarrays 2026-08-01 12:01:46 1
betr
 
Resource Report
Resource Website
10+ mentions
betr (RRID:SCR_001332) betr software resource Software package that implements the Bayesian Estimation of Temporal Regulation algorithm to identify differentially expressed genes in microarray time-course data. differentially expression, gene, microarray, time-course is listed by: OMICtools
has parent organization: Bioconductor
PMID:20003283 Free, Available for download, Freely available OMICS_01997 http://www.bioconductor.org/packages/release/bioc/html/betr.html SCR_001332 Bayesian Estimation of Temporal Regulation 2026-08-01 12:01:48 17
gprege
 
Resource Report
Resource Website
1+ mentions
gprege (RRID:SCR_001324) gprege software resource Software R package for Gaussian Process Ranking and Estimation of Gene Expression time-series. The software fits two Gaussian processes (GPs) with an radial basis function (RBF) (+ noise diagonal) kernel on each profile. One GP kernel is initialized wih a short lengthscale hyperparameter, signal variance as the observed variance and a zero noise variance. It is optimized via scaled conjugate gradients (netlab). A second GP has fixed hyperparameters: zero inverse-width, zero signal variance and noise variance as the observed variance. The log-ratio of marginal likelihoods of the two hypotheses acts as a score of differential expression for the profile. Comparison via receiver operating characteristic curves (ROC curves) is performed against Bayesian hierarchical model for the analysis of time-series (BATS) (Angelini et.al, 2007). differential expression, microarray, preprocessing, time course, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:21599902 Free, Available for download, Freely available OMICS_02011, biotools:gprege http://www.bioconductor.org/packages/release/bioc/html/gprege.html SCR_001324 Gaussian Process Ranking and Estimation of Gene Expression time-series 2026-08-01 12:01:38 1
waveTiling
 
Resource Report
Resource Website
waveTiling (RRID:SCR_001322) waveTiling software resource Software package to conduct transcriptome analysis for tiling arrays based on fast wavelet-based functional models. differential expression, microarray, gene expression, time course is listed by: OMICtools
has parent organization: Bioconductor
PMID:22974078 Free, Available for download, Freely available OMICS_02014 http://www.bioconductor.org/packages/release/bioc/html/waveTiling.html SCR_001322 waveTiling - Wavelet-Based Models for Tiling Array Transcriptome Analysis 2026-08-01 12:01:27 0

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