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A community-driven ontology that is developed to standardize and integrate cell line information and support computer-assisted reasoning. Its focus is on permanent cell lines from culture collections. Upper ontology structures that frame the skeleton of CLO include Basic Formal Ontology and Relation Ontology. Cell lines contained in CLO are associated with terms from other ontologies such as Cell Type Ontology, NCBI Taxonomy, and Ontology for Biomedical Investigation. A common design pattern for the cell line is used to model cell lines and their attributes, the Jurkat cell line provides ane xample. Currently CLO contains over 36,000 cell line entries obtained from ATCC, HyperCLDB, Coriell, and bymanual curation. The cell lines are derived from 194 cell types, 656 anatomical entries, and 217 organisms. The OWL-based CLO is machine-readable and can be used in various applications. The CLO development has become a community effort with international collaborations. The development consortium includes experts from all over the world: the USA, Europe, and Japan.
Proper citation: Cell Line Ontology (RRID:SCR_005840) Copy
http://purl.bioontology.org/ontology/RCD
Ontology of clinical terms Version 3 (CTV3) (Read Codes) (Q199): National Health Service National Coding and Classification Centre
Proper citation: Read Codes Clinical Terms Version 3 (RRID:SCR_006055) Copy
http://purl.bioontology.org/ontology/RCTONT
Ontology specifically for Randomized Controlled Trials in order to facilitate the production of systematic reviews and metaanalysis.
Proper citation: Randomized Controlled Trials Ontology (RRID:SCR_005992) Copy
http://purl.bioontology.org/ontology/RETO
An application ontology for the domain of gene transcription regulation. The ontology integrates fragments of GO and MI with data from GOA, IntAct, UniProt, NCBI, KEGG and orthology relations.
Proper citation: Regulation of Transcription Ontology (RRID:SCR_006238) Copy
An ontology for the description of biological and clinical investigations built with international, collaborative effort. The ontology represents the design of an investigation, the protocols and instrumentation used, the material used, the data generated and the type analysis performed on it. This includes a set of universal terms that are applicable across various biological and technological domains, and domain-specific terms relevant only to a given domain. Currently OBI is being built under the Basic Formal Ontology (BFO). This project was formerly titled the Functional Genomics Investigation Ontology (FuGO) project.
Proper citation: Ontology for Biomedical Investigations (RRID:SCR_006266) Copy
Online catalog of human genes and genetic disorders, for clinical features, phenotypes and genes. Collection of human genes and genetic phenotypes, focusing on relationship between phenotype and genotype. Referenced overviews in OMIM contain information on all known mendelian disorders and variety of related genes. It is updated daily, and entries contain copious links to other genetics resources.
Proper citation: OMIM (RRID:SCR_006437) Copy
http://purl.bioontology.org/ontology/BDO
Ontology that provides a comprehensive and formal representation of the different domain concepts involved in documenting the full complexity of the skeletal dysplasia domain. It captures and combines the genetic features that discriminate the bone dysplasias with the multitude of phenotypic characteristics manifested by patients and required to be taken into account in order to support the diagnosis process.
Proper citation: Bone Dysplasia Ontology (RRID:SCR_006588) Copy
http://purl.bioontology.org/ontology/SPTO
Ontology for Solanaceae crop phenotypes and traits, developed in collaboration with the research community, especially for breeder traits of agronomic importance.
Proper citation: Solanaceae Phenotype Ontology (RRID:SCR_007832) Copy
http://purl.bioontology.org/ontology/SOY
Growth, trait and development ontology for soybean
Proper citation: Soy Ontology (RRID:SCR_007847) Copy
http://purl.bioontology.org/ontology/HCPCS
Ontology for the healthcare common procedure coding system.
Proper citation: Healthcare Common Procedure Coding System (RRID:SCR_007598) Copy
http://purl.bioontology.org/ontology/DIKB
An evidence taxonomy for pharmacologic studies that, when combined with a set of inclusion criteria, enable drug experts to specify what their confidence in a drug mechanism assertion would be if it were supported by a specific set of evidence.
Proper citation: Drug Interaction Knowledge Base Ontology (RRID:SCR_007591) Copy
http://purl.bioontology.org/ontology/CHD
An ontology that describes the Congenital Heart Defects data.
Proper citation: Congenital Heart Defects Ontology (RRID:SCR_007584) Copy
http://purl.bioontology.org/ontology/SSE
Memorial Sloan-Kettering Cancer Center''s ontology of surgical secondary events (adverse events).
Proper citation: Surgical Secondary Events (RRID:SCR_007894) Copy
http://purl.bioontology.org/ontology/LIPRO
An ontology that describes the LIPIDMAPS nomenclature classification explicitly using description logics (OWL-DL). Lipid classes are organized hierarchically with the super-classes restricted by generic necessary conditions. More specific necessary conditions are used to define membership requirements for sub classes of lipid according to appropriate functional groups. Lipid research is increasingly integrated within systems level biology such as lipidomics where lipid classification is required before appropriate annotation of chemical functions can be applied.
Proper citation: Lipid Ontology (RRID:SCR_003349) Copy
http://purl.bioontology.org/ontology/MMO
An ontology designed to represent the variety of methods used to make qualitative and quantitative clinical and phenotype measurements both in the clinic and with model organisms.
Proper citation: Measurement Method Ontology (RRID:SCR_003373) Copy
http://sig.biostr.washington.edu/projects/fm/
A domain ontology that represents a coherent body of explicit declarative knowledge about human anatomy. It is concerned with the representation of classes or types and relationships necessary for the symbolic representation of the phenotypic structure of the human body in a form that is understandable to humans and is also navigable, parseable and interpretable by machine-based systems. Its ontological framework can be applied and extended to all other species. The description of how the OWL version was generated is in Pushing the Envelope: Challenges in a Frame-Based Representation of Human Anatomy by N. F. Noy, J. L. Mejino, C. Rosse, M. A. Musen: http://bmir.stanford.edu/publications/view.php/pushing_the_envelope_challenges_in_a_frame_based_representation_of_human_anatomy The Foundational Model of Anatomy ontology has four interrelated components: # Anatomy taxonomy (At), # Anatomical Structural Abstraction (ASA), # Anatomical Transformation Abstraction (ATA), # Metaknowledge (Mk), The ontology contains approximately 75,000 classes and over 120,000 terms; over 2.1 million relationship instances from over 168 relationship types link the FMA's classes into a coherent symbolic model.
Proper citation: FMA (RRID:SCR_003379) Copy
http://purl.bioontology.org/ontology/IDOMAL
An application ontology to cover all aspects of malaria (clinical, epidemiological, biological, etc) as well as the intervention attempts to control it, extending the infectious disease ontology (IDO).
Proper citation: Malaria Ontology (RRID:SCR_003369) Copy
http://purl.bioontology.org/ontology/DDANAT
A structured controlled vocabulary of the anatomy of the slime-mould Dictyostelium discoideum.
Proper citation: Dictyostelium Discoideum Anatomy Ontology (RRID:SCR_003309) Copy
http://purl.bioontology.org/ontology/MAT
An ontology of minimal set of terms for anatomy.
Proper citation: Minimal Anatomical Terminology (RRID:SCR_003385) Copy
http://www.bioontology.org/wiki/index.php/CARO:Main_Page
An ontology developed to facilitate interoperability between existing anatomy ontologies for different species, and to provide a template for building new anatomy ontologies.
Proper citation: Common Anatomy Reference Ontology (RRID:SCR_003296) Copy
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