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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GOLEM An interactive, graphical gene-ontology visualization, navigation, and analysis tool
 
Resource Report
Resource Website
1+ mentions
GOLEM An interactive, graphical gene-ontology visualization, navigation, and analysis tool (RRID:SCR_003191) GOLEM production service resource, data analysis service, source code, analysis service resource, service resource, software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented July 7, 2017. Welcome to the home of GOLEM: An interactive, graphical gene-ontology visualization, navigation,and analysis tool on the web. GOLEM is a useful tool which allows the viewer to navigate and explore a local portion of the Gene Ontology (GO) hierarchy. Users can also load annotations for various organisms into the ontology in order to search for particular genes, or to limit the display to show only GO terms relevant to a particular organism, or to quickly search for GO terms enriched in a set of query genes. GOLEM is implemented in Java, and is available both for use on the web as an applet, and for download as a JAR package. A brief tutorial on how to use GOLEM is available both online and in the instructions included in the program. We also have a list of links to libraries used to make GOLEM, as well as the various organizations that curate organism annotations to the ontology. GOLEM is available as a .jar package and a macintosh .app for use on- or off- line as a stand-alone package. You will need to have Java (v.1.5 or greater) installed on your system to run GOLEM. Source code (including Eclipse project files) are also available. GOLEM (Gene Ontology Local Exploration Map)is a visualization and analysis tool for focused exploration of the gene ontology graph. GOLEM allows the user to dynamically expand and focus the local graph structure of the gene ontology hierarchy in the neighborhood of any chosen term. It also supports rapid analysis of an input list of genes to find enriched gene ontology terms. The GOLEM application permits the user either to utilize local gene ontology and annotations files in the absence of an Internet connection, or to access the most recent ontology and annotation information from the gene ontology webpage. GOLEM supports global and organism-specific searches by gene ontology term name, gene ontology id and gene name. CONCLUSION: GOLEM is a useful software tool for biologists interested in visualizing the local directed acyclic graph structure of the gene ontology hierarchy and searching for gene ontology terms enriched in genes of interest. It is freely available both as an application and as an applet. gene ontology, ontology visualization, ontology analysis is related to: Gene Ontology
has parent organization: Princeton University; New Jersey; USA
NIGMS R01 GM071966;
NSF IIS-0513552;
NIGMS P50 GM071508
PMID:17032457 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-30620 https://lsi.princeton.edu/golem-interactive-graph-based-gene-ontology-navigation-and-analysis-tool SCR_003191 GOLEM An interactive graphical gene-ontology visualization navigation and analysis tool, GOLEM An interactive graphical gene-ontology visualization navigation analysis tool 2026-08-03 09:32:00 3
KOBAS
 
Resource Report
Resource Website
1000+ mentions
KOBAS (RRID:SCR_006350) KOBAS production service resource, data analysis service, analysis service resource, service resource, software resource Web server to identify statistically enriched pathways, diseases, and GO terms for a set of genes or proteins, using pathway, disease, and GO knowledge from multiple famous databases. It allows for both ID mapping and cross-species sequence similarity mapping. It then performs statistical tests to identify statistically significantly enriched pathways and diseases. KOBAS 2.0 incorporates knowledge across 1327 species from 5 pathway databases (KEGG PATHWAY, PID, BioCyc, Reactome and Panther) and 5 human disease databases (OMIM, KEGG DISEASE, FunDO, GAD and NHGRI GWAS Catalog). A standalone command line version is also available, THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. ortholog, pathway, disease, gene, protein, annotation, command line, FASEB list is listed by: OMICtools
is related to: Gene Ontology
is related to: KEGG
is related to: OMIM
is related to: Pathway Interaction Database
is related to: BioCarta Pathways
is related to: Reactome
is related to: BioCyc
is related to: PANTHER
is related to: FunDO
is related to: Genetic Association Database
is related to: GWAS: Catalog of Published Genome-Wide Association Studies
has parent organization: Peking University; Beijing; China
PMID:21715386 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02228 SCR_006350 KEGG Orthology Based Annotation System 2026-08-03 09:33:03 4787
MGI GO Browser
 
Resource Report
Resource Website
1+ mentions
MGI GO Browser (RRID:SCR_006489) MGI GO Browser production service resource, data analysis service, service resource, database, analysis service resource, data or information resource With the MGI GO Browser, you can search for a GO term and view all mouse genes annotated to the term or any subterms. You can also browse the ontologies to view relationships between terms, term definitions, as well as the number of mouse genes annotated to a given term and its subterms. The MGI GO browser directly accesses the GO data in the MGI database, which is updated nightly. Platform: Online tool gene, ontology, browser, molecular function, biological process, cellular component, ontology or annotation browser, ontology or annotation search engine, ontology or annotation visualization is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Mouse Genome Informatics (MGI)
Free for academic use nlx_149104 SCR_006489 2026-08-03 09:33:02 7
Gene Ontology For Functional Analysis (GOFFA)
 
Resource Report
Resource Website
1+ mentions
Gene Ontology For Functional Analysis (GOFFA) (RRID:SCR_006484) GOFFA software resource, data processing software, software application, data analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 23,2023. Software tool developed for ArrayTrack that takes a list of genes and identifies terms in Gene Ontology associated with those genes. GOFFA provides tools to view/access the following: GO term hierarchy, full listing of GO terms annotated with the genes associated with a given term, Fisher's exact test p-value providing the probability of identifying that many genes for a given term by chance alone, and relative enrichment factor (E-value) giving the enrichment of a GO term for genes in the submitted list relative to the frequency of genes assigned to that term from the full set of GOFFA annotated genes for a particular species. gene ontology, proteomic, visualization, fisher's exact test, browser, search engine, term enrichment, text mining, ontology browser, annotation browser, ontology visualization, annotation visualization, database, data warehouse, software, identify term is used by: ArrayTrack
is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: National Center for Toxicological Research
PMID:17118145 THIS RESOURCE IS NO LONGER IN SERVICE nlx_149101 http://edkb.fda.gov/webstart/arraytrack/ SCR_006484 Gene Ontology For Functional Analysis 2026-08-03 09:33:02 7
Ontology Lookup Service
 
Resource Report
Resource Website
10+ mentions
Ontology Lookup Service (RRID:SCR_006596) OLS web service, database, source code, data access protocol, data or information resource, software resource Interactive and programmatic interfaces to query, browse and navigate an increasing number of biomedical ontologies and controlled vocabularies. It provides a web service interface to query multiple ontologies from a single location with a unified output format. It can integrate any ontology available in the Open Biomedical Ontology (OBO) format. The database can be queried to obtain information on a single term or to browse a complete ontology using AJAX. Auto-completion provides a user-friendly search mechanism. An AJAX-based ontology viewer is available to browse a complete ontology or subsets of it. A weekly MySQL database export file can be downloaded from the EBI public FTP directory. ontology, ontology or annotation browser, ontology or annotation search engine, gold standard lists: Cell Type Ontology
is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: OBO-Edit
is related to: OBO
has parent organization: European Bioinformatics Institute
BBSRC ;
iSPIDER ;
European Union FP6 Felics contract 021902 (RII3)
PMID:18467421
PMID:16507094
Apache License, v2, Acknowledgement requested OMICS_02275, nif-0000-10390, r3d100010413 https://doi.org/10.17616/R3GS9G http://www.ebi.ac.uk/ols SCR_006596 OLS - Ontology Lookup Service, Ontology Lookup Service (OLS) 2026-08-03 09:33:07 24
Mouse Genome Informatics: The Gene Ontology Project
 
Resource Report
Resource Website
10+ mentions
Mouse Genome Informatics: The Gene Ontology Project (RRID:SCR_006447) controlled vocabulary, data or information resource, database This resource is part of the Gene Ontology Consortium which seeks to provide controlled vocabularies for the description of the molecular function, biological process, and cellular component of gene products. These terms are to be used as attributes of gene products by collaborating databases, facilitating uniform queries across them. GO team members at MGI participate in ontology development, outreach, and functional curation of mouse gene products. The GO vocabularies have a hierarchical structure that permits a range of detail from high-level, broadly descriptive terms to very low level, highly specific terms. This broad range is useful both in annotating genes and in searching for gene information using these terms as search criteria. GO terms are defined, allowing all databases to use the terms consistently and properly. GO annotations in the databases additionally include the publication reference which allowed the association to be made and an evidence statement citing how the association was determined. function, gene, biological, cellular, component, molecular, process, product is affiliated with: Gene Ontology
has parent organization: Jackson Laboratory
NHGRI HG002273 Available to the research community nif-0000-10304 SCR_006447 Gene Ontology (GO) Project, MGI: GO Project, Gene Ontology Project 2026-08-03 09:33:01 12
InnateDB
 
Resource Report
Resource Website
100+ mentions
InnateDB (RRID:SCR_006714) InnateDB data or information resource, database Publicly available database of the genes, proteins, experimentally-verified interactions and signaling pathways involved in the innate immune response of humans, mice and bovines to microbial infection. The database captures coverage of the innate immunity interactome by integrating known interactions and pathways from major public databases together with manually-curated data into a centralized resource. The database can be mined as a knowledgebase or used with the integrated bioinformatics and visualization tools for the systems level analysis of the innate immune response. Although InnateDB curation focuses on innate immunity-relevant interactions and pathways, it also incorporates detailed annotation on the entire human, mouse and bovine interactomes by integrating data (178,000+ interactions & 3,900+ pathways) from several of the major public interaction and pathway databases. InnateDB also has integrated human, mouse and bovine orthology predictions generated using Ortholgue software. Ortholgue uses a phylogenetic distance-based method to identify possible paralogs in high-throughput orthology predictions. Integrated human and mouse conserved gene order and synteny information has also been determined to provide further support for orthology predictions. InnateDB Capabilities: * View statistics for manually-curated innate immunity relevant molecular interactions. New manually curated interactions are submitted weekly. * Search for genes and proteins of interest. * Search for experimentally-verified molecular interactions by gene/protein name, interaction type, cell type, etc. * Search genes/interactions belonging to 3,900 pathways. * Visualize interactions using an intuitive subcellular localization-based layout in Cerebral. * Upload your own list of genes along with associated gene expression data (from up to 10 experimental conditions) to interactively analyze this data in a molecular interaction network context. Once you have uploaded your data, you will be able to interactively visualize interaction networks with expression data overlaid; carry out Pathway, Gene Ontology and Transcription Factor Binding Site over-representation analyses; construct orthologous interaction networks in other species; and much more. * Access curated interaction data via a dedicated PSICQUIC webservice. gene, immune response, pathway, protein, signaling pathway, interaction, immune, signaling response, gene, orthology prediction, orthology, ortholg, annotation, interactome, gene expression, molecule, protein-protein interaction, molecular interaction, visualization, nucleic acid-protein, nucleic acid, network, web service, transcription factor binding site, software resource, FASEB list is listed by: re3data.org
is related to: IMEx - The International Molecular Exchange Consortium
is related to: Interaction Reference Index
is related to: ConsensusPathDB
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
is related to: PSICQUIC Registry
is related to: Gene Ontology
is related to: IntAct
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: University of British Columbia; British Columbia; Canada
works with: IMEx - The International Molecular Exchange Consortium
Microbial infection, Allergy, Asthma Michael Smith Foundation for Health Research ;
AllerGen 12ASI1;
AllerGen 12B&B2;
Teagasc RMIS6018;
European Union PSIMEx project contract FP7-HEALTH-2007-223411
PMID:23180781
PMID:18766178
Free, Freely available nif-0000-20808, r3d100010676 https://doi.org/10.17616/R36S43 SCR_006714 A Knowledge Resource for Innate Immunity Interactions and Pathways, InnateDB: Systems Biology of the Innate Immune Response, InnateDB - A Knowledge Resource for Innate Immunity Interactions and Pathways 2026-08-03 09:33:08 496
canSAR
 
Resource Report
Resource Website
50+ mentions
canSAR (RRID:SCR_006794) canSAR production service resource, data analysis service, service resource, database, analysis service resource, data or information resource canSAR is an integrated database that brings together biological, chemical, pharmacological (and eventually clinical) data. Its goal is to integrate this data and make it accessible to cancer research scientists from multiple disciplines, in order to help with hypothesis generation in cancer research and support translational research. This cancer research and drug discovery resource was developed to utilize the growing publicly available biological annotation, chemical screening, RNA interference screening, expression, amplification and 3D structural data. Scientists can, in a single place, rapidly identify biological annotation of a target, its structural characterization, expression levels and protein interaction data, as well as suitable cell lines for experiments, potential tool compounds and similarity to known drug targets. canSAR has, from the outset, been completely use-case driven which has dramatically influenced the design of the back-end and the functionality provided through the interfaces. The Web interface provides flexible, multipoint entry into canSAR. This allows easy access to the multidisciplinary data within, including target and compound synopses, bioactivity views and expert tools for chemogenomic, expression and protein interaction network data. molecular target, expression, cell line, compound, molecule, protein, structure, ligand, drug, 3d, genomics, 3d complex, bioactivity, protein affinity, cell line sensitivity, pathway, annotation, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: BindingDB
is related to: Gene Ontology
has parent organization: Cancer Research UK
Cancer Cancer Research UK C309/A8274 PMID:22013161 CanSAR is freely available to all cancer researchers. By using canSAR you are agreeing to the Terms of Use, Https://cansar.icr.ac.uk/cansar/terms-of-use/ biotools:cansar, nlx_149410 https://bio.tools/cansar SCR_006794 2026-08-03 09:33:10 54
Aging Portal
 
Resource Report
Resource Website
Aging Portal (RRID:SCR_000496) Aging portal, database, topical portal, catalog, data or information resource Portal devoted to aging relevant scientific data and resources. late adult human, senescence uses: Aging Genes and Interventions Database
uses: anage
uses: Human Life-Table Database
uses: Gene Ontology
uses: Grants.gov
uses: Integrated Blogs
uses: Integrated Clinical Trials
uses: Integrated Videos
uses: Integrated Grants
uses: Lifespan Observations Database
uses: One Mind Biospecimen Bank Listing
uses: Gait in Parkinson's Disease
uses: SciCrunch Registry
has parent organization: SciCrunch
Aging NIA 1R03AG043018-01 Restricted nlx_158366 SCR_000496 2026-08-03 09:31:04 0
MEME Suite - Motif-based sequence analysis tools
 
Resource Report
Resource Website
1000+ mentions
MEME Suite - Motif-based sequence analysis tools (RRID:SCR_001783) MEME Suite production service resource, data analysis service, data or information resource, software application, database, data processing software, data analysis software, source code, analysis service resource, service resource, software resource Suite of motif-based sequence analysis tools to discover motifs using MEME, DREME (DNA only) or GLAM2 on groups of related DNA or protein sequences; search sequence databases with motifs using MAST, FIMO, MCAST or GLAM2SCAN; compare a motif to all motifs in a database of motifs; associate motifs with Gene Ontology terms via their putative target genes, and analyze motif enrichment using SpaMo or CentriMo. Source code, binaries and a web server are freely available for noncommercial use. gene ontology, motif, comparative genomics, dna regulatory motif, dna sequence, dna, gene, transcription factor, genome, protein, analysis, function analysis, comparison, cluster, enrichment analysis, sequence analysis, bio.tools, FASEB list lists: DREME
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Glam2
is related to: ANNOgesic
is related to: memesuite-lite
has parent organization: National Biomedical Computation Resource
is parent organization of: GOMO - Gene Ontology for Motifs
NCRR R01 RR021692 PMID:19458158
DOI:10.1093/nar/gkl198
Free, Freely available nif-0000-10298, biotools:meme_suite, OMICS_08103 https://bio.tools/meme_suite http://meme.sdsc.edu/meme4_6_1/intro.html, http://meme.nbcr.net/meme/, https://sources.debian.org/src/meme/ SCR_001783 The MEME Suite 2026-08-03 09:31:30 2091
AmiGO
 
Resource Report
Resource Website
1000+ mentions
AmiGO (RRID:SCR_002143) AmiGO production service resource, data analysis service, service resource, database, analysis service resource, data or information resource Web tool to search, sort, analyze, visualize and download data of interest. Along with providing details of the ontologies, gene products and annotations, features a BLAST search, Term Enrichment and GO Slimmer tools, the GO Online SQL Environment and a user help guide.Used at the Gene Ontology (GO) website to access the data provided by the GO Consortium. Developed and maintained by the GO Consortium. search, sort, analyze, visualize, data, ontology, gene, annotation, FASEB list uses: GOlr
is used by: NIF Data Federation
is listed by: OMICtools
is listed by: Gene Ontology Tools
is related to: ASAP
is related to: Candida Genome Database
is related to: Berkeley Bioinformatics Open-Source Projects
is related to: ECO
is related to: Zebrafish Information Network (ZFIN)
is related to: Gramene
is related to: WormBase
is related to: NCBI Protein Database
is related to: UniProtKB
is related to: GeneDB Lmajor
is related to: TAIR
is related to: SGD
is related to: GeneDB Tbrucei
is related to: VMD
is related to: JCVI CMR
is related to: go-db-perl
is related to: Mouse Genome Informatics (MGI)
is related to: NCBI
is related to: FlyBase
is related to: GeneDB Pfalciparum
is related to: PomBase
is related to: Pseudomonas Genome Database
is related to: Dictyostelium discoideum genome database
is related to: Plant Ontology
is related to: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
is related to: MeGO
is related to: ASPGD
is related to: EcoCyc
is related to: Reactome
is related to: SGN
is related to: GO-Module
is related to: Songbird Brain Transcriptome Database
is related to: Rat Genome Database (RGD)
is related to: RamiGO
has parent organization: Gene Ontology
NHGRI P41 HG002273 PMID:19033274 Free, Available for download, Freely available nif-0000-20935, OMICS_02266 http://sourceforge.net/projects/geneontology/ SCR_002143 GO Consortium, AmiGO, AmiGO 2, AmiGene Ontology, Gene Ontology Database, Gene Ontology Consortium, GO Database, The Gene Ontology Consortium 2026-08-03 09:31:34 1242
Generic GO Term Finder
 
Resource Report
Resource Website
100+ mentions
Generic GO Term Finder (RRID:SCR_008870) GOTermFinder, GO-TermFinder, GO Term Finder, GO::TermFinder production service resource, data analysis service, software application, data processing software, source code, analysis service resource, service resource, software resource The Generic GO Term Finder finds the significant GO terms shared among a list of genes from an organism, displaying the results in a table and as a graph (showing the terms and their ancestry). The user may optionally provide background information or a custom gene association file or filter evidence codes. This tool is capable of batch processing multiple queries at once. GO::TermFinder comprises a set of object-oriented Perl modules GO::TermFinder can be used on any system on which Perl can be run, either as a command line application, in single or batch mode, or as a web-based CGI script. This implementation, developed at the Lewis-Sigler Institute at Princeton, depends on the GO-TermFinder software written by Gavin Sherlock and Shuai Weng at Stanford University and the GO:View module written by Shuai Weng. It is made publicly available through the GMOD project. The full source code and documentation for GO:TermFinder are freely available from http://search.cpan.org/dist/GO-TermFinder/. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene ontology, gene, graph, visualization, genomics, gene association, ontology or annotation visualization, term enrichment, ontology, process, function, component, enrichment, bio.tools is listed by: 3DVC
is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Generic Model Organism Database Project
has parent organization: Princeton University; New Jersey; USA
has parent organization: Comprehensive Perl Archive Network
NHGRI 1R01HG002732 PMID:15297299 Free for academic use nlx_149293, biotools_go_term_finder https://bio.tools/go_term_finder SCR_008870 Generic Gene Ontology (GO) Term Finder, Generic Gene Ontology Term Finder 2026-08-03 09:34:14 108
Agile Protein Interactomes DataServer
 
Resource Report
Resource Website
10+ mentions
Agile Protein Interactomes DataServer (RRID:SCR_008871) APID production service resource, data analysis service, web service, data or information resource, database, analysis service resource, data access protocol, service resource, software resource APID Interactomes (Agile Protein Interactomes DataServer) provides information on the protein interactomes of numerous organisms, based on the integration of known experimentally validated protein-protein physical interactions (PPIs). The interactome data includes a report on quality levels and coverage over the proteomes for each organism included. APID integrates PPIs from primary databases of molecular interactions (BIND, BioGRID, DIP, HPRD, IntAct, MINT) and also from experimentally resolved 3D structures (PDB) where more than two distinct proteins have been identified. This collection references protein interactors, through a UniProt identifier. protein, protein interaction, interactions, ppi, interactomes, analysis, gene, ontology, functional, environment, data, network, graphic, visualize is listed by: Gene Ontology Tools
is related to: PSICQUIC Registry
is related to: Gene Ontology
is related to: BIND
is related to: Biological General Repository for Interaction Datasets (BioGRID)
is related to: Database of Interacting Proteins (DIP)
is related to: HPRD - Human Protein Reference Database
is related to: IntAct
is related to: MINT
has parent organization: University of Salamanca; Salamanca; Spain
Spanish Ministerio de Sanidad y Consumo ;
Junta de Castilla y Leon
PMID:27131791
PMID:30715274
Free for academic use r3d100012339, nlx_149321 https://doi.org/10.17616/R3407P, https://doi.org/10.17616/R3407P SCR_008871 Agile Protein Interactomes DataServer, APID, APID Interactomes, Agile Protein Interactomes DataServer (APID), APID (Agile Protein Interactomes DataServer) 2026-08-03 09:33:58 14
LegumeIP
 
Resource Report
Resource Website
10+ mentions
LegumeIP (RRID:SCR_008906) LegumeIP production service resource, data analysis service, service resource, database, analysis service resource, data or information resource LegumeIP is an integrative database and bioinformatics platform for comparative genomics and transcriptomics to facilitate the study of gene function and genome evolution in legumes, and ultimately to generate molecular based breeding tools to improve quality of crop legumes. LegumeIP currently hosts large-scale genomics and transcriptomics data, including: * Genomic sequences of three model legumes, i.e. Medicago truncatula, Glycine max (soybean) and Lotus japonicus, including two reference plant species, Arabidopsis thaliana and Poplar trichocarpa, with the annotation based on UniProt TrEMBL, InterProScan, Gene Ontology and KEGG databases. LegumeIP covers a total 222,217 protein-coding gene sequences. * Large-scale gene expression data compiled from 104 array hybridizations from L. japonicas, 156 array hybridizations from M. truncatula gene atlas database, and 14 RNA-Seq-based gene expression profiles from G. max on different tissues including four common tissues: Nodule, Flower, Root and Leaf. * Systematic synteny analysis among M. truncatula, G. max, L. japonicus and A. thaliana. * Reconstruction of gene family and gene family-wide phylogenetic analysis across the five hosted species. LegumeIP features comprehensive search and visualization tools to enable the flexible query on gene annotation, gene family, synteny, relative abundance of gene expression. gene function, genome evolution, legume, gene, genome, plant, genomics, transcriptomic, gene annotation, gene family, synteny, gene expression, blast, genomic sequence, microarray, rna-seq, comparative genomics, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is related to: UniProt
is related to: InterProScan
is related to: Gene Ontology
is related to: KEGG
has parent organization: Samuel Roberts Noble Foundation
Samuel Roberts Noble Foundation ;
NSF ABI-0960897
PMID:22110036 biotools:legumeip, nlx_151455 https://bio.tools/legumeip SCR_008906 LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes, LegumeIP - An Integrative Platform to Study Gene Function and Genome Evolution in Legumes 2026-08-03 09:34:10 19
GOMO - Gene Ontology for Motifs
 
Resource Report
Resource Website
1+ mentions
GOMO - Gene Ontology for Motifs (RRID:SCR_008864) GOMO production service resource, data analysis service, software application, data processing software, analysis service resource, service resource, software resource Gene Ontology for Motifs (GOMO) is an alignment- and threshold-free comparative genomics approach for assigning functional roles to DNA regulatory motifs from DNA sequence. The algorithm detects associations between a user-specified DNA regulatory motif (expressed as a position weight matrix; PWM) and Gene Ontology terms. The original method for predicting the roles of transcription factors (TFs starts with a PWM motif describing the DNA-binding affinity of the TF. GOMO uses the PWM to score the promoter region of each gene in the genome for its likelihood to be bound by the TF. The resulting ''''affinity'''' scores are then used to test each term in the Gene Ontology for association with high-scoring genes. The algorithm was subsequently extended to leverage conserved signals using multiple, related species in a comparative approach, which greatly improves the resulting annotations. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, motif, genomics, gene ontology, function, compare, ontology or annotation editor, statistical analysis, dna binding motif, dna binding, dna, transcription factor, sequence is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Queensland; Brisbane; Australia
has parent organization: MEME Suite - Motif-based sequence analysis tools
Australian Research Council ;
University of Queensland; Brisbane; Australia ;
International Research Tuition Award ;
NCRR R01 RR021692
PMID:20147307
PMID:18544606
Free for academic use nlx_149250 SCR_008864 Gene Ontology for Motifs 2026-08-03 09:34:09 3
Onto-Express To Go (OE2GO)
 
Resource Report
Resource Website
Onto-Express To Go (OE2GO) (RRID:SCR_008854) OE2GO production service resource, data analysis service, software application, analysis service resource, text-mining software, service resource, software resource Onto-Express is a web-based tool in the Onto-Tools suite that performs automated function profiling for a list of differentially expressed genes. However, Onto-Express does not support functional profiling for the organisms that do not have annotations in public domain, or use of custom (i.e. user-defined) ontologies. This limitation is also true for most of the other existing tools for functional profiling, which means that researchers working with uncommon organisms and/or new annotations or ontologies may be forced to construct such profiles manually. Onto-Express To Go (OE2GO) is a new tool added to the Onto-Tools ensemble to address these issues. OE2GO is built on top of OE to leverage its existing functionality. In OE2GO, the users now have an option to use either the Onto-Tools database as a source of functional annotations or provide their own annotations in a separate file. Currently, OE2GO supports annotation file in the Gene Ontology format. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene, gene expression, annotation, data mining, ontology browser, annotation browser, ontology search engine, annotation search engine, ontology visualization, annotation visualization, statistical analysis, term enrichment, browser, visualization, search engine is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: Wayne State University; Michigan; USA
PMID:17584796 Free for academic use nlx_149112 SCR_008854 Onto-Express-to-go, Onto-Express To Go 2026-08-03 09:33:58 0
Renal Disease Portal
 
Resource Report
Resource Website
Renal Disease Portal (RRID:SCR_009030) Renal Disease Portal portal, disease-related portal, topical portal, data or information resource, data set An integrated resource for information on genes, QTLs and strains associated with a variety of kidney and renal system conditions such as Renal Hypertension, Polycystic Kidney Disease and Renal Insufficiency, as well as Kidney Neoplasms. gene, quantitative trait locus, strain, renal hypertension, kidney neoplasm, phenotype, pathway, biological process, disease, kidney, genome, gviewer, chromosome, molecular function, cellular component, visualization, synteny is related to: NIDDK Information Network (dkNET)
is related to: Gene Ontology
has parent organization: Rat Genome Database (RGD)
Renal disease, Renal hypertension, Polycystic kidney disease, Renal insufficiency, Kidney neoplasm, Diabetes Insipidus, Hyperoxaluria, Renal hypertension, Nephritis, Nephrocalcinosis, Nephrolithiasis, Nephrosis, Renal Fibrosis, Inborn Error of Renal Tubular Transport, Uremia nlx_153941 SCR_009030 RGD Renal Disease Portal 2026-08-03 09:34:19 0
UBERON
 
Resource Report
Resource Website
50+ mentions
UBERON (RRID:SCR_010668) UBERON controlled vocabulary, data or information resource, ontology An integrated cross-species anatomy ontology representing a variety of entities classified according to traditional anatomical criteria such as structure, function and developmental lineage. The ontology includes comprehensive relationships to taxon-specific anatomical ontologies, allowing integration of functional, phenotype and expression data. Uberon consists of over 10000 classes (March 2014) representing structures that are shared across a variety of metazoans. The majority of these classes are chordate specific, and there is large bias towards model organisms and human. anatomy, comparative, evolution, organ system, anatomical structure, body part, organ, tissue, body, vertebrate, function, phenotype, expression, model organism, obo is used by: Neuroscience Information Framework
is listed by: BioPortal
is related to: Gene Ontology
has parent organization: OBO
ARRA ;
NSF ;
NHGRI 5R01HG004838;
NHGRI P41HG002273;
DOE DE-AC02-05CH11231;
NCRR 1U24RR029825-01;
NHGRI P41HG002273-09S1
PMID:22293552 nlx_74404 SCR_010668 Uber anatomy ontology, Uber-anatomy ontology 2026-08-03 09:34:52 59
Algal Functional Annotation Tool
 
Resource Report
Resource Website
Algal Functional Annotation Tool (RRID:SCR_012034) Algal Functional Annotation Tool production service resource, data analysis service, data or information resource, database, analysis service resource, service resource Tools to search gene lists for functional term enrichment as well as to dynamically visualize proteins onto pathway maps. Additionally, integrated expression data may be used to discover similarly expressed genes based on a starting gene of interest. gene, pathway, visualization, annotation, function, protein family, ontology, protein, genomics is listed by: OMICtools
is related to: Gene Ontology
is related to: KEGG
is related to: MetaCyc
is related to: Reactome
is related to: Pfam
is related to: InterPro
has parent organization: University of California at Los Angeles; California; USA
DOE ;
NAABB ;
IGP ;
Air Force Office of Scientific Research
PMID:21749710 OMICS_02226 SCR_012034 2026-08-03 09:34:47 0
L2L Microarray Analysis Tool
 
Resource Report
Resource Website
1+ mentions
L2L Microarray Analysis Tool (RRID:SCR_013440) L2L data repository, production service resource, data analysis service, service resource, software application, data processing software, database, data analysis software, storage service resource, analysis service resource, data or information resource, software resource THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone.. Documented on August 26, 2019.

Database of published microarray gene expression data, and a software tool for comparing that published data to a user''''s own microarray results. It is very simple to use - all you need is a web browser and a list of the probes that went up or down in your experiment. If you find L2L useful please consider contributing your published data to the L2L Microarray Database in the form of list files. L2L finds true biological patterns in gene expression data by systematically comparing your own list of genes to lists of genes that have been experimentally determined to be co-expressed in response to a particular stimulus - in other words, published lists of microarray results. The patterns it finds can point to the underlying disease process or affected molecular function that actually generated the observed changed in gene expression. Its insights are far more systematic than critical gene analyses, and more biologically relevant than pure Gene Ontology-based analyses. The publications included in the L2L MDB initially reflected topics thought to be related to Cockayne syndrome: aging, cancer, and DNA damage. Since then, the scope of the publications included has expanded considerably, to include chromatin structure, immune and inflammatory mediators, the hypoxic response, adipogenesis, growth factors, hormones, cell cycle regulators, and others. Despite the parochial origins of the database, the wide range of topics covered will make L2L of general interest to any investigator using microarrays to study human biology. In addition to the L2L Microarray Database, L2L contains three sets of lists derived from Gene Ontology categories: Biological Process, Cellular Component, and Molecular Function. As with the L2L MDB, each GO sub-category is represented by a text file that contains annotation information and a list of the HUGO symbols of the genes assigned to that sub-category or any of its descendants. You don''''t need to download L2L to use it to analyze your microarray data. There is an easy-to-use web-based analysis tool, and you have the option of downloading your results so you can view them at any time on your own computer, using any web browser. However, if you prefer, the entire L2L project, and all of its components, can be downloaded from the download page. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible
microarray, gene expression, adipogenesis, biological, biological process, cancer, cell cycle regulator, cellular component, chromatin, cockayne syndrome, dna damage, growth factor, hormone, human biology, hypoxic response, immune mediator, inflammatory mediator, molecular function, molecular neuroanatomy resource, adipocyte, development, hypoxia, immune, inflammation, metabolism, mitogen, neuro, rna, vascular, transcription, tissue, splicing, mouse, human, rat, source code, statistical analysis, gene, chromatin structure is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Washington; Seattle; USA
Cockayne syndrome, DNA damage, Other, Aging, Cancer Cora May Poncin Foundation ;
NIGMS GM41624
PMID:16168088 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10463 http://depts.washington.edu/l2l/about.html SCR_013440 L2L Microarray Database, L2L Microarray Analysis Tool: A simple tool for discovering the hidden biological significance in microarray expression data, L2L MDB 2026-08-03 09:35:15 1

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