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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.huck.psu.edu/core-facilities/cryo-electron-microscopy-facility
Cryo-Electron Microscopy Facility houses FEI Titan Krios microscope that offers data collection for life sciences while incorporating materials science applications. Used for creating super high definition 3D images of atoms and molecules. Facility allows for fully automated atomic resolution single particle and high contrast tomography tilt-series data collection. Additional microscopy components permit a full range of materials science applications, including EELS, STEM, and DPC. Facility also houses ThermoFisher Arctica G2.
Proper citation: Pennsylvania State University Huck Institutes Cryo-Electron Microscopy Core Facility (RRID:SCR_024456) Copy
https://tnprc.tulane.edu/infectious-disease-aerobiology-core
Core focuses on infectious disease aerobiology. Core facilitates biomedical research efforts that require unique demands of aerosol and aerobiology in their respective performance.
Proper citation: Tulane University TNBRC Infectious Disease Aerobiology Core Facility (RRID:SCR_024608) Copy
https://tnprc.tulane.edu/clinical-pathology-core
Clinical Pathology Core performs clinical diagnostic testing for all research and colony animals. This includes complete blood counts, routine chemistry panels, and microbial culture workups. The lab is equipped with Sysmex XN1000v veterinary hematology analyzer, Beckman AU480 chemistry analyzer, and Matrix assisted laser desorption ionization time of flight MALDI-TOF instrument for microbe identification. CPC is staff with American Society of Clinical Pathologist certified licensed Medical Technologists.
Proper citation: Tulane University TNBRC Clinical Pathology Core Facility (RRID:SCR_024609) Copy
https://tnprc.tulane.edu/anatomic-pathology-core
Anatomic Pathology Core is responsible for post-mortem examinations, tissue collection and distribution, fixation, processing, slide preparation, routine and special staining, and diagnostic gross and histologic pathology services. Processes and interprets biopsy specimens for both research and diagnostic purposes and provides tissue trimming, paraffin processing, sectioning, and routine and special staining for clinical and research staff and faculty. APC works closely with clinical veterinarians, and through diagnostic pathology on biopsies and necropsies, plays major role in monitoring and maintaining health of animals in breeding colonies.
Proper citation: Tulane University TNBRC Anatomic Pathology Core Facility (RRID:SCR_024606) Copy
https://www.huck.psu.edu/core-facilities/proteomics-and-mass-spectrometry-core-facility
Facility offers highly sensitive and accurate mass spectrometry analysis, including identification and quantitation of proteins by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS-MS) or by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-TOF-MS).
Proper citation: Pennsylvania State University Huck Institutes Proteomics and Mass Spectrometry Core Facility (RRID:SCR_024462) Copy
https://www.huck.psu.edu/core-facilities/microscopy-facility
Microscopy facility specializes in areas of optical microscopy, electron microscopy, and histology. Facility is equipped with confocal microscopes, research fluorescence microscopes, and transmission and scanning electron microscopes. Research staff engage in experimentation, training, project collaboration, and consultation.
Proper citation: Pennsylvania State University Huck Institutes Microscopy Core Facility (RRID:SCR_024457) Copy
https://tnbrc.tulane.edu/cores-and-services/flow-cytometry
Core provides analytical flow cytometry services and live cell sorting under enhanced Biosafety Level 2 conditions. Instruments available include six analyzers ranging from 4-30 color acquisition and three sorters using 1-,2-,4-way, and plate sorting between 6-18 colors. Provides experimental and panel design consultation. Provides continued education in seminar format and one-on-one sessions with user.
Proper citation: Tulane University TNBRC Flow Cytometry Core Facility (RRID:SCR_024611) Copy
https://www.huck.psu.edu/core-facilities/fermentation-facility
Biotechnology pilot plant capable of research and pilot scale production of microbial cells, recombinant proteins, and other microbial products over wide range of controlled conditions. Facility provides equipment and expertise to university affiliated and independent government and industry researchers interested in fermentation and related technologies, including cell separation and disruption, biomolecule production and purification, and process monitoring.
Proper citation: Pennsylvania State University Huck Institutes CSL Behring Fermentation Core Facility (RRID:SCR_024459) Copy
https://tnprc.tulane.edu/confocal-microscopy-and-molecular-pathology-core
Core provides research support and training with molecular pathology skills, confocal microscopy, image analysis, and multicolor immunohistochemistry and in-situ hybridization techniques for internal and affiliate scientists. Services include assistance with experimental design, antibody selection, molecular probe selection, fixation and staining protocols, operating fluorescent and confocal microscopes, acquiring and storing imaging data, interpretation of results, and generation of publication-quality images. Image analysis services include assistance with capturing images for evaluation and with use of various image analysis software.
Proper citation: Tulane University TNBRC Confocal Microscopy and Molecular Pathology Core Facility (RRID:SCR_024613) Copy
https://www.uml.edu/research/crf/ourlabs/nanofab-lab.aspx
Core features 4,200 ft2 Class 100 clean room equipped with over 40 pieces of process and analytical instrumentation for complex research projects that require micro and nano scale fabrication.
Proper citation: University of Massachusetts Lowell Nanofabrication Lab Core Facility (RRID:SCR_024734) Copy
https://tnprc.tulane.edu/pathogen-detection-and-quantification-core
THIS RESOURCE IS NO LONGER AVAILABLE. SAME SERVICES ARE AVAILABLE IN Molecular Virology and Sequencing Core. Documented on January 28,2025. Core provides services for maintaining Specific Pathogen Free status in macaque breeding colonies. Services include antibody detection in serum or plasma by Luminex-based assays and /or ELISA for SPF-agents like SIV, SRV, STLV, B virus, SFV. CMV, RRV, SVV, SV40, and LCV, and non-SPF infectious agents like measles, Burkholderia pseudomallei, Tripanosoma cruzi, Mycobacterium tuberculosis, and SARS-CoV-2. Offers services of cytokines quantification, and molecular assays for detection of SRV, CMV, SFV, and RRV.Performs nucleic acid purification from blood and tissue samples as well as qPRC for SIV viral load in plasma, cells, or tissue.
Proper citation: Tulane University TNPRC Pathogen Detection and Quantification Core Facility (RRID:SCR_024614) Copy
https://www.library.upenn.edu/holman/bollinger-digital-fabrication
Provides fabrication services and consultations contributing to innovation in teaching, learning, research, and clinical care at the University of Pennsylvania.
Proper citation: University of Pennsylvania Bollinger Digital Fabrication Laboratory Core Facility (RRID:SCR_024735) Copy
https://www.uml.edu/research/crf/ourlabs/microscopy-core-lab.aspx
Core offers micro-imaging and micro-analysis solutions by providing access to several photon-, scanned probe-, ion beam-, and electron beam-based imaging and analytical instruments, services, and technical expertise for characterization of materials including nano-engineered materials, microelectronics, photonics, biomaterials, and others with applications in life sciences, drug discovery, environmental and energy research. Consultative services are also available.
Proper citation: University of Massachusetts Lowell Microscopy Core Facility (RRID:SCR_024677) Copy
http://faculty.washington.edu/maga/SCRI_MicroCT/
Shared instrument facility that has a Bruker Skyscan 1272 ex-vivo microCT that is capable of X-ray imaging at sub-microb resolution. The instrument can optionally be equipped with a 16-sample sample changer to automate the scanning queue. Core provides visualization and image analysis support for researchers, using open-source 3D Slicer biomedical imaging suite.
Proper citation: Seattle Children's Research Institute Micro Computed Tomography Imaging and Visualization Lab Core Facility (RRID:SCR_024678) Copy
https://biotech.unl.edu/flow-cytometry#tab1
Provides flow cytometry services. Instruments include Beckman Coulter CytoFLEX SRT sorter and CytoFLEX LX, as well as NanoAnalyzer from NanoFCM. Facility staff are able to assist with everything from experimental design, instrument training, sample collection, and data analysis.
Proper citation: University of Nebraska Lincoln Flow Cytometry Core Facility (RRID:SCR_024711) Copy
Core provides instrumentation for light and fluorescence based microscopy, including epifluorescence, confocal, and super-resolution imaging.Provides access to and training on basic and advanced light microscopy techniques. Expertise and advice is available for the design of experiments involving these techniques.
Proper citation: University of Wisconsin-Madison Biochemistry Optical Core Facility (RRID:SCR_023952) Copy
Core for collaborative human neuroscience research provides access to technology and expertise to high density electroencephalography recording and transcranial magnetic stimulation studies in human subjects.
Proper citation: Stanford University Koret Human Neurosciences Community Laboratory Core Facility (RRID:SCR_024528) Copy
https://www.sdstate.edu/genomics-sequencing-facility
Facility offers custom sequencing services from DNA/RNA extractions to sequencing using Illumina and Oxford Nanopore platforms. Projects examples include bulk RNAseq, 3\'RNASeq, Single Cell transcriptomics (10X Genomics), Genome sequencing, and amplicon sequencing (ie 16SRNA, genotyping). Services include experimental design and bioinformatics data analysis.
Proper citation: South Dakota State University Genomics Sequencing Core Facility (RRID:SCR_023959) Copy
Imaging core and shared resource facility. Provides electron microscopy services, education, and training. Equipped with high resolution transmission electron microscopes, scanning electron microscopes, high pressure freezer and ancillary sample preparation equipment. The equipment can provide nanometer scale analysis for biological, chemical and materials science. Offers Project consultation, Education and training for new users, Equipment for trained users who anticipate having long term EM projects, Full service microscopy.
Proper citation: University of California at Berkeley Electron Microscope Laboratory Core Facility (RRID:SCR_024544) Copy
https://health.uconn.edu/cell-analysis-modeling/microscopy-facility/
CCAM Microscopy Facility provides access to equipment for quantitative fluorescence imaging applications. Instruments include laser scanning confocal microscopes equipped with 34 channel highefficiency QUASAR detectors. One of these microscopes supports nonlinear optical excitation, fluorescence correlation spectroscopy, and fluorescence lifetime imaging microscopy. Additionally, there is a light sheet microscope available for micro/mesoscale 3D imaging. The Zeiss Elyra 7 microscope is capable of total internal reflection fluorescence microscopy and supports several super resolution techniques such as lattice structured illumination microscopy, stochastic optical reconstruction microscopy, 3D photoactivated localization microscopy, and DNA points accumulation for imaging in nanoscale topography.
Proper citation: University of Connecticut Health Center for Cell Analysis and Modeling Microscopy Core Facility (RRID:SCR_024655) Copy
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