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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
REDfly Regulatory Element Database for Drosophilia
 
Resource Report
Resource Website
10+ mentions
REDfly Regulatory Element Database for Drosophilia (RRID:SCR_006790) REDfly storage service resource, data repository, service resource, database, data or information resource Curated collection of known Drosophila transcriptional cis-regulatory modules (CRMs) and transcription factor binding sites (TFBSs). Includes experimentally verified fly regulatory elements along with their DNA sequence, associated genes, and expression patterns they direct. Submission of experimentally verified cis-regulatory elements that are not included in REDfly database are welcome. transcriptional cis-regulatory module, transcription factor binding site, dna sequence, gene, expression pattern, genome, gene expression, transcription factor, cis-regulatory module, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Drosophila anatomy and development ontologies
is related to: FlyMine
has parent organization: University at Buffalo; New York; USA
NSF EF0843229;
NIGMS U24 GM144232
PMID:20965965
PMID:18039705
PMID:16303794
Acknowledgement requested OMICS_01870, biotools:redfly, nif-0000-03393 https://bio.tools/redfly SCR_006790 Regulatory Element Database for Drosophilia, Regulatory Element Database 2026-08-04 09:41:42 14
WSsas - Web Service for the SAS tool
 
Resource Report
Resource Website
WSsas - Web Service for the SAS tool (RRID:SCR_007051) WSsas data access protocol, software resource, web service SAS is a tool for applying structural information to a given protein sequence. It uses FASTA to scan a given protein sequence against all the proteins of known 3D structure in the Protein Data Bank and provides functional residue annotation based on data from the Catalytic Site Atlas and PDBsum. The web service is aimed to facilitate the use of the SAS tool when having a huge number of queries. Currently, the web service provides annotation for binding sites (to ligand, metal or nucleic acid), catalytic residues and amino acids related to protein-protein interactions. gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: SAS - Sequence Annotated by Structure
has parent organization: European Bioinformatics Institute
nlx_18182, biotools:wssas https://bio.tools/wssas SCR_007051 Web Service for the SAS tool 2026-08-04 09:41:44 0
AutismKB
 
Resource Report
Resource Website
10+ mentions
AutismKB (RRID:SCR_006937) AutismKB data analysis service, analysis service resource, production service resource, service resource, database, data or information resource Genetic factors contribute significantly to ASD. AutismKB is an evidence-based knowledgebase of Autism spectrum disorder (ASD) genetics. The current version contains 2193 genes (99 syndromic autism related genes and 2135 non-syndromic autism related genes), 4617 Copy Number Variations (CNVs) and 158 linkage regions associated with ASD by one or more of the following six experimental methods: # Genome-Wide Association Studies (GWAS); # Genome-wide CNV studies; # Linkage analysis; # Low-scale genetic association studies; # Expression profiling; # Other low-scale gene studies. Based on a scoring and ranking system, 99 syndromic autism related genes and 383 non-syndromic autism related genes (434 genes in total) were designated as having high confidence. Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder with a prevalence of 1.0-2.6%. The three core symptoms of ASD are: # impairments in reciprocal social interaction; # communication impairments; # presence of restricted, repetitive and stereotyped patterns of behavior, interests and activities. gene, copy number variation, linkage region, genome-wide association study, family-based association study, case-control association study, expression profile, blast, syndromic, non-syndromic, snp, vntr, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: Peking University; Beijing; China
Autism spectrum disorder, Autism Merck ;
Johnson and Johnson ;
Natural Science Foundation of China 31025014;
Natural Science Foundation of China 2011CBA01102
PMID:22139918 biotools:autismkb, nlx_151318 https://bio.tools/autismkb SCR_006937 Autism Knowledgebase 2026-08-04 09:41:42 33
Expression Database in 4D
 
Resource Report
Resource Website
1+ mentions
Expression Database in 4D (RRID:SCR_007066) 4DXpress storage service resource, data repository, service resource, database, data or information resource This database provides a platform to query and compare gene expression data during the development of the major model animals (zebrafish, drosophila, medaka, mouse). The name 4DXpress stands for expression database in 4D. The 4D (four dimensions) of 4DXpress can be interpreted either as: 3 spatial dimensions plus time, or as 1. species 2. gene 3. developmental stage 4. anatomical structure. The major focus of this database lies in cross species comparison. The high resolution expression data was acquired through whole mount in situ hybridsation-, antibody- or transgenic experiments. Data was integrated from several species specific expression pattern databases, such as ZFIN, BDGP, GXD, MEPD as well as directly submitted by researchers of the participating groups at EMBL. The 4DXpress database is a project within the Centre for Computational Biology at EMBL. It is developed by Yannick Haudry, Thorsten Henrich and Ivica Letunic and coordinated by Thorsten Henrich. Hugo Berube is developing the 4D ArrayExpress Data Warehouse at EBI for integrating in situ data with microarray data. genes, anatomical structures, developmental stage, microarray data, species, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
European Molecular Biology Laboratory; Heidelberg; Germany PMID:17916571 nif-0000-02524, biotools:4dxpress https://bio.tools/4dxpress SCR_007066 4DXpress Database 2026-08-04 09:41:45 1
SimSeq
 
Resource Report
Resource Website
10+ mentions
SimSeq (RRID:SCR_006947) SimSeq simulation software, software application, software resource An illumina paired-end and mate-pair short read simulator. This project attempts to model as many of the quirks that exist in Illumina data as possible. Some of these quirks include the potential for chimeric reads, and non-biotinylated fragment pull down in mate-pair libraries . bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Free biotools:simseq, OMICS_00258 https://bio.tools/simseq SCR_006947 2026-08-04 09:41:43 29
larvalign
 
Resource Report
Resource Website
1+ mentions
larvalign (RRID:SCR_015815) data processing software, data analysis software, data set, software resource, sequence analysis software, software application, software toolkit, data or information resource Software package including computational methods for aligning gene expression patterns from the larval brain of Drosophila melanogaster. Its method includes evaluation of the registration framework involved in template generation and mapping. drosophila melanogaster, computational method, gene expression, alignment, larval brain, larvae, template generation, mapping, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download biotools:larvalign https://bio.tools/larvalign SCR_015815 2026-08-04 09:43:45 1
TreeDyn
 
Resource Report
Resource Website
100+ mentions
TreeDyn (RRID:SCR_015946) data processing software, data visualization software, software application, software resource Visualization software that links unique leaf labels to lists of variables/values pairs of annotations (meta-information), independently of the tree topologies, remaining fully compatible with the basic newick format. These relationships are used by dynamic graphics operators, information visualization methods like Projection, Localization, Labelization, Reflection allowing an interaction from annotations to trees, from trees to annotations and from trees to trees through annotations., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. tree, variable, annotation, metainfo, newick, topology, graphic, operator, projection, localization, reflection, leaf, label, bio.tools is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE biotools:treedyn https://bio.tools/treedyn SCR_015946 2026-08-04 09:43:47 355
SC3
 
Resource Report
Resource Website
10+ mentions
SC3 (RRID:SCR_015953) data processing software, data analysis software, software resource, sequence analysis software, software application Software tool for the unsupervised clustering of cells from single cell RNA-Seq experiments. SC3 is capable of identifying subclones from the transcriptomes of neoplastic cells collected from patients. scRNA-seq, interactive, cluster, clustering, cell, single, rna, rnaseq, bio.tools is listed by: Debian
is listed by: bio.tools
Wellcome Trust 104710/Z/14/Z;
Belgian Network DYSCO ;
FRS-FNRS ;
Belgian State Science Policy Office ;
ARC (Action de Recherche Concerte) ;
Wallonia-Brussels Federation ;
EPSRC EP/N014529/1;
Sanger Institute ;
University of Edinburgh ;
Bloodwise 13003;
MRC ;
Kay Kendall Leukaemia Fund ;
Cambridge NIHR Biomedical Research Center ;
Cambridge Experimental Cancer Medicine Centre ;
Leukemia and Lymphoma Society of America 07037
PMID:28346451 Free, Available for download biotools:sc3 https://bio.tools/sc3 SCR_015953 SC3 package, Single-Cell Consensus Clustering 2026-08-04 09:43:46 20
Canu
 
Resource Report
Resource Website
1000+ mentions
Canu (RRID:SCR_015880) data processing software, data analysis software, software resource, sequence analysis software, software application Software for scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation. Canu is a fork of the Celera Assembler and is designed for high-noise single-molecule sequencing (such as the PacBio RS II/Sequel or Oxford Nanopore MinION). long-read, assembly, k-mer, weighting, repeat separation, adaptive, pacbio, single-molecule, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Celera assembler
National Human Genome Research Institute ;
US Department of Homeland Security (DHS) HSHQDC-07-C-00020;
National Science Foundation NSF IOS-1237993
PMID:28298431
DOI:10.1101/071282
Free, Available for download biotools:canu, OMICS_14592 http://canu.readthedocs.io/en/latest/, https://bio.tools/canu, https://sources.debian.org/src/canu/ SCR_015880 2026-08-04 09:43:45 2255
Genesis
 
Resource Report
Resource Website
1000+ mentions
Genesis (RRID:SCR_015775) data processing software, data analysis software, software resource, software application, data visualization software Software for cluster analysis of microarray data. Genesis is a platform independent Java package of tools to simultaneously visualize and analyze a whole set of gene expression experiments. cluster analysis, microarray data, java, gene expression, visualization, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
PMID:11836235 Free for academic use, Free for non-profits, Available for download, Runs on Windows, Runs on Mac OS, Runs on Linux biotools:genesis_microarray https://bio.tools/genesis_microarray SCR_015775 Genesis: Cluster analysis of microarray data 2026-08-04 09:43:43 1018
Barrnap
 
Resource Report
Resource Website
500+ mentions
Barrnap (RRID:SCR_015995) data processing software, data analysis software, software resource, sequence analysis software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software to predict the location of ribosomal RNA genes in genomes. It supports bacteria, archaea, mitochondria, and eukaryotes. It takes FASTA DNA sequence as input, writes GFF3 as output, and supports multithreading., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. multithreading, fasta, sequencing, software, predict, location, ribosomal, gene, genome, RNA, prediction, bacteria, archaea, mitochondria, eukaryote, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE biotools:barrnap, OMICS_13988 https://github.com/tseemann/barrnap, https://bio.tools/barrnap, https://sources.debian.org/src/barrnap/ SCR_015995 Barrnap: Basic rapid ribosomal RNA predictor 2026-08-04 09:43:47 568
HyPhy
 
Resource Report
Resource Website
1000+ mentions
HyPhy (RRID:SCR_016162) data processing software, data analysis software, software resource, sequence analysis software, software application, software toolkit Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning. analysis, genetic, sequence, multiply, alignment, rate, pattern, data, evolution, platform, python, r, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NSF DBI-0096033;
NSF DEB-9996118;
NIH R01 AI47745;
NIH U01 AI43638;
University of California Universitywide AIDS Research Program IS02-SD-701;
University of California ;
San Diego Center for AIDS Research/NIAID Developmental Award 2 P30 AI36214;
NIGMS R01
PMID:15509596 Free, Available for download, Freely available SCR_016271, biotools:HyPhy, OMICS_04235 https://sources.debian.org/src/hyphy-pt/, https://veg.github.io/hyphy-site/, https://github.com/veg/hyphy, https://bio.tools/HyPhy, SCR_016162 HyPhy:Hypothesis Testing using Phylogenies, Hyphy-pt 2026-08-04 09:43:49 1497
zUMIs
 
Resource Report
Resource Website
100+ mentions
zUMIs (RRID:SCR_016139) data processing software, software application, software resource, data analysis software Software pipeline to process RNA-seq data with UMIs. The input to this pipeline is paired-end fastq files, where one read contains the cDNA sequence and the other read contains UMI and Cell Barcode information. single-cell, RNA-seq, UMI, Genomics, shell, r, perl, rna, cdna, cell, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1101/153940 Open source, Free, Available for download biotools:zumis https://bio.tools/zumis SCR_016139 zumi 2026-08-04 09:43:49 118
Fastml
 
Resource Report
Resource Website
100+ mentions
Fastml (RRID:SCR_016092) web application, data access protocol, software resource, web service Web application for the reconstruction of ancestral sequences. It computes maximum likelihood ancestral sequence reconstruction based on the phylogenetic relations between homologous sequences. ancestral, amino-acid, sequence, reconstruction, phylogenetic, relation, accurate, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Israel Science Foundation 878/09;
Bioinformatics Center at Tel-Aviv University
PMID:22661579 Free, Freely available biotools:fastml, OMICS_08650 https://bio.tools/fastml, https://sources.debian.org/src/fastml/ SCR_016092 The FastML Server 2026-08-04 09:43:48 109
BioPlex
 
Resource Report
Resource Website
1000+ mentions
BioPlex (RRID:SCR_016144) storage service resource, data repository, service resource, database, data or information resource Database of cell lines with each expressing a tagged version of a protein from the ORFeome collection. The overarching project goal is to determine protein interactions for every member of the collection. cell, line, protein, immunopurification, mass, spectrometry, interaction, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Harvard Medical School; Massachusetts; USA
NHGRI U41HG006673;
NIDDK K01 DK098285;
Canadian Institutes for Health Research
PMID:28514442 biotools:bioplex_2.0 https://bio.tools/bioplex_2.0 SCR_016144 BioPlex (biophysical interactions of ORFeome-based complexes), Harvard BioPlex, Biophysical Interactions of Orfeome-based comPLEXes (BioPLEX) 2026-08-04 09:43:49 1355
mentha
 
Resource Report
Resource Website
100+ mentions
mentha (RRID:SCR_016148) data processing software, data analysis software, software resource, software application, web application, database, data or information resource Software that archives evidence collected from different sources, then analyzes and presents these data. Its data come from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. protein, ppi, imex, interactome, archival, bio.tools, FASEB list uses: PSICQUIC Registry
is listed by: Debian
is listed by: bio.tools
is related to: IMEx - The International Molecular Exchange Consortium
PMID:23900247 biotools:mentha, r3d100011124 https://bio.tools/mentha, https://doi.org/10.17616/R3SP8V SCR_016148 2026-08-04 09:43:50 149
DISULFIND
 
Resource Report
Resource Website
50+ mentions
DISULFIND (RRID:SCR_016072) Disulfinder data processing software, data analysis software, software resource, sequence analysis software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023, Software for predicting the disulfide bonding state of cysteines and their disulfide connectivity, starting from a protein sequence alone and may be useful in other genomic annotation tasks. predict, disulfide, bonding, state, cysteine, protein, sequence, genomic, annotation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
has parent organization: University of Florence; Florence; Italy
EU STREP APrIL II contract no. FP6-508861;
EU NoE BIOPATTERN contract no. FP6-508803;
Embark Fellowship from the Irish Research Council for Science ;
Engineering and Technology
PMID:16844986
DOI:10.1093/nar/gkl266
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04214, biotools:disulfind https://bio.tools/disulfind, https://sources.debian.org/src/disulfinder/ SCR_016072 Cysteines Disulfide Bonding State and Connectivity Predictor 2026-08-04 09:43:49 66
Exonerate
 
Resource Report
Resource Website
100+ mentions
Exonerate (RRID:SCR_016088) data processing software, alignment software, software resource, software application, image analysis software, software toolkit Software package for sequence alignment of pairwise sequence comparison. Exonerate can be used to align sequences using many alignment models, exhaustive dynamic programming, or a variety of heuristics., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence, alignment, pairwise, comparison, dynamic, programming, heuristic, bio.tools is used by: ExonerateTransferAnnotation
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:15713233 THIS RESOURCE IS NO LONGER IN SERVICE biotools:exonerate https://bio.tools/exonerate SCR_016088 2026-08-04 09:43:48 374
Bio++
 
Resource Report
Resource Website
50+ mentions
Bio++ (RRID:SCR_016055) software development tool, software resource, software application, software library, software toolkit Software providing a set of ready-to-use C++ libraries as re-usable tools to visualize, edit, print and output data for bioinformatics. It uses sequence analysis, phylogenetics, molecular evolution and population genetics to help to write programs., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. phylogenetic, molecular evolution, genetic, program, write, tool, visualize, edit, print, data, bioinformatic, sequence analysis, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_15696, biotools:biopp https://sources.debian.org/src/bppsuite/, https://groups.google.com/forum/#!categories/biopp-help-forum/all-questions, https://github.com/BioPP, https://bio.tools/biopp, SCR_016055 Bppsuite, Bppphyview, Bio++ program suite, Bio++ Phylogenetic Viewer 2026-08-04 09:43:48 65
EnrichmentMap
 
Resource Report
Resource Website
500+ mentions
EnrichmentMap (RRID:SCR_016052) data processing software, source code, software resource, software application, data visualization software Source code of a Cytoscape plugin for functional enrichment visualization. It organizes gene-sets, such as pathways and Gene Ontology terms, into a network to reveal which mutually overlapping gene-sets cluster together. cytoscape, functional, visualization, enrichment, gene, mapping, genome, pathway, network, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is a plug in for: Cytoscape
NHGRI P41 HG04118;
Ontario Genomics Institute ;
Heart and Stroke Foundation of Canada ;
Canada Foundation for Innovation ;
Ontario Research Fund (ORF)
PMID:21085593 biotools:enrichmentmap https://github.com/BaderLab/EnrichmentMapApp, https://bio.tools/enrichmentmap SCR_016052 2026-08-04 09:43:48 545

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