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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Online Resource for Community Annotation of Eukaryotes
 
Resource Report
Resource Website
10+ mentions
Online Resource for Community Annotation of Eukaryotes (RRID:SCR_014989) OrcAE, ORCAE data or information resource, narrative resource, wiki Online genome annotation tool for validating and correcting gene annotations. OrcAE is community-driven and can be edited by account-holders in the research community. genome annotation, gene validation, community driven, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Bioinformatics Gent
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:23132114 Free, Account required, The research community can contribute to this resource biotools:orcae https://bio.tools/orcae SCR_014989 Online Resource for Community Annotation of Eukaryotes (OrcAE) 2026-09-12 12:58:24 17
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) data analysis software, data processing software, data visualization software, sequence analysis software, software application, software resource Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview, https://sources.debian.org/src/seaview/ SCR_015059 2026-09-12 12:58:25 1817
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) data analysis software, data processing software, sequence analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX, https://bio.tools/MeroX, https://bio.tools/MeroX SCR_014956 2026-09-12 12:58:23 74
BUSCO
 
Resource Report
Resource Website
5000+ mentions
BUSCO (RRID:SCR_015008) algorithm resource, data analysis software, data processing software, software application, software resource Software tool to quantitatively measure genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. genome assembly, annotation completeness, quantitative method, bio.tools is used by: rnaQUAST
is recommended by: CEGMA
is listed by: Debian
is listed by: bio.tools
is related to: CEGMA
works with: BUSCOMP
Marie Curie International Outgoing Fellowship ;
Swiss National Science Foundation
DOI:10.1093/bioinformatics/btv351 Free, Available for download, Freely available biotools:busco https://gitlab.com/ezlab/busco, https://bio.tools/busco, https://sources.debian.org/src/busco/ SCR_015008 BUSCO v2, Benchmarking Universal Single-Copy Orthologs (BUSCO), Benchmarking Universal Single-Copy Orthologs, BUSCO v1 2026-09-12 12:58:24 8320
GIIRA
 
Resource Report
Resource Website
1+ mentions
GIIRA (RRID:SCR_015507) data analysis software, data processing software, sequence analysis software, software application, software resource Gene prediction method that identifies potential coding regions based on the mapping of reads from an RNA-Seq experiment. gene prediction, rna seq, coding region, potential coding region is listed by: Debian
is listed by: OMICtools
DOI:10.1093/bioinformatics/btt577 Available for download OMICS_07360 http://www.rki.de/EN/Content/Institute/DepartmentsUnits/JuniorGroups/JRG4.html, https://sources.debian.org/src/giira/ SCR_015507 2026-09-12 12:58:27 3
LTR_Finder
 
Resource Report
Resource Website
500+ mentions
LTR_Finder (RRID:SCR_015247) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web software capable of scanning large-scale sequences for full-length LTR retrotranspsons., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Long Terminal Repeat retrotransposons, Long Terminal Repeat, retrotransposon prediction, genome sequences, LTR prediction, LTR structure prediction, DNA sequence, biotools is listed by: Debian
is listed by: bio.tools
Fudan University ;
Shanghai ;
China
PMID:17485477 THIS RESOURCE IS NO LONGER IN SERVICE SCR_020944, biotools:ltr_finder https://bio.tools/ltr_finder SCR_015247 LTR Finder 2026-09-12 12:58:26 807
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) data analysis software, data processing software, sequence analysis software, software application, software resource, source code Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2, https://bio.tools/hisat2, https://sources.debian.org/src/hisat2/ SCR_015530 HISAT 2026-09-12 12:58:27 20753
SEER
 
Resource Report
Resource Website
500+ mentions
SEER (RRID:SCR_015499) data analysis software, data processing software, sequence analysis software, software application, software resource, source code Sequence element enrichment analysis tool to perform pan-genome-wide association studies in bacteria. bacterial genome association, sequence element enrichment analysis, kmer enrichment analysis is listed by: Debian
is listed by: OMICtools
is hosted by: GitHub
DOI:10.1038/ncomms12797
DOI:10.1101/038463
Available for download OMICS_21699 https://sources.debian.org/src/seer/ SCR_015499 2026-09-12 12:58:27 547
primers4clades
 
Resource Report
Resource Website
1+ mentions
primers4clades (RRID:SCR_015714) software resource, web application Web application for the design of PCR primers for cross-species amplification of novel sequences from metagenomic DNA or from uncharacterized organisms belonging to user-specified phylogenetic lineages. It implements an extended CODEHOP strategy and evaluates thermodynamic properties of the oligonucleotide pairs. pcr primer, metagenomic dna, phylogenetic lineage, primer, clade, bio.tools is listed by: Debian
is listed by: bio.tools
DGAPA IN201806-2;
CONACyT-Mexico P1-60071;
CSIC 200720I038
PMID:19465390 Freely available, Free for academic use, Tutorial available biotools:primers4clades http://maya.ccg.unam.mx/primers4clades, https://bio.tools/primers4clades SCR_015714 2026-09-12 12:58:29 2
clustergrammer
 
Resource Report
Resource Website
10+ mentions
clustergrammer (RRID:SCR_015681) data visualization tool, software tool Clustergrammer is a web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable hierarchically clustered heatmaps. Clustergrammer enables intuitive exploration of high-dimensional data and has several optional biology-specific features. bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/sdata.2017.151 biotools:clustergrammer https://bio.tools/clustergrammer SCR_015681 2026-09-12 12:58:29 48
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) data analysis software, data processing software, software application, software resource, source code Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-09-12 12:58:29 1808
BSVF
 
Resource Report
Resource Website
1+ mentions
BSVF (RRID:SCR_015727) BSVF data analysis software, data processing software, sequence analysis software, software application, software resource, source code Software code for bisulfite sequencing virus integration. This finder is for directional libraries only and does not support PBAT and indirectional libraries. virus integration, sequencing analysis, virus assembly, integration, bisulfite, bio.tools is listed by: bio.tools
is listed by: Debian
Open source biotools:bs-virus-finder https://bio.tools/bs-virus-finder SCR_015727 BSVF: Bisulfite Sequencing Virus integration Finder, Bisulfite Sequencing Virus integration Finder 2026-09-12 12:58:29 1
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) electronic laboratory notebook, software application, software resource, systems interoperability software, web application Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-09-12 12:58:29 3
DISEASES
 
Resource Report
Resource Website
500+ mentions
DISEASES (RRID:SCR_015664) data or information resource, database Database that integrates evidence on disease-gene associations from automatic text mining, manually curated literature, cancer mutation data, and genome-wide association studies. It also assigns confidence scores that facilitate comparison of the different types and sources of evidence. disease, gene, disease-gene association, text-mining, , bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation Center for Protein Research NNF14CC0001;
European Union Seventh Framework Programme n259348
PMID:25484339 biotools:diseases https://bio.tools/diseases SCR_015664 2026-09-12 12:58:28 655
TISSUES
 
Resource Report
Resource Website
10+ mentions
TISSUES (RRID:SCR_015665) data or information resource, database, software resource, web application Database that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. It maps all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unifies it by assigning confidence scores that facilitate comparison of the different types and sources of evidence. tissue expression, proteomic, transcriptomic, text-mining, brenda tissue ontology, protein identifier, bio.tools uses: BRENDA Tissue and Enzyme Source Ontology
is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation NNF14CC0001;
NCI U54 CA189205-01;
CSIRO’s OCE Science Leader program
PMID:26157623 Freely available, Free, Available for download biotools:tissues https://bio.tools/tissues SCR_015665 TISSUES: Tissue Expression Database, Tissue Expression Database 2026-09-12 12:58:28 45
Hybrid-denovo
 
Resource Report
Resource Website
1+ mentions
Hybrid-denovo (RRID:SCR_015866) data analysis software, data processing software, sequence analysis software, software application, software resource Software for a de novo OTU-picking pipeline integrating single- and paired-end 16S sequence tags. It is designed to take Illumina paired-end sequencing reads as input and output the OTU BIOM table, together with their representative sequences and a phylogenetic tree of OTUs. hybrid-denovo, 16S rRNA, microbiota pipeline, single-end, paired-end, illumina read, de novo, otu-picking pipeline, phylogenetic tree, python, bio.tools is listed by: bio.tools
is listed by: Debian
biotools:hybrid-denovo https://bio.tools/hybrid-denovo SCR_015866 2026-09-12 12:58:31 3
Short Read Sequence Typing for Bacterial Pathogens
 
Resource Report
Resource Website
10+ mentions
Short Read Sequence Typing for Bacterial Pathogens (RRID:SCR_015870) SRST2 data analysis software, data processing software, sequence analysis software, software application, software resource, source code Software that is designed to take Illumina sequence data, a MLST database and/or a database of gene sequences (e.g. resistance genes, virulence genes, etc) and report the presence of STs and/or reference genes. genotype analysis, illumina sequence data, mlst database, gene sequence, st, reference gene, short read uses: Bowtie
uses: SAMTOOLS
is listed by: Debian
is listed by: OMICtools
requires: SciPy
requires: Python Programming Language
infectious disease NHMRC of Australia 1043830;
NHMRC of Australia 1061409;
NHMRC of Australia 1061435;
Victorian Life Sciences Computation Initiative (VLSCI) VR0082
PMID:25422674 Free, Available for download OMICS_12777 http://katholt.github.io/srst2/, https://sources.debian.org/src/srst2/ http://srst.sourceforge.net/ SCR_015870 SRST2: Short Read Sequence Typing for Bacterial Pathogens, Short Read Sequence Typing v2 2026-09-12 12:58:32 24
NiftyPET
 
Resource Report
Resource Website
1+ mentions
NiftyPET (RRID:SCR_015873) data processing software, data visualization software, image analysis software, software application, software resource, software toolkit, source code Python software package that offers quantitative PET image reconstruction and analysis with high accuracy and precision. It is written in CUDA C and embedded in Python C extensions. python, cuda c, python c, pet, image reconstruction, image analysis, bio.tools uses: CMake
is listed by: Debian
is listed by: bio.tools
DOI:10.1007/s12021-017-9352-y Free, Available for download, Runs on Windows, Runs on Linux biotools:niftypet https://bio.tools/niftypet SCR_015873 2026-09-12 12:58:32 7
larvalign
 
Resource Report
Resource Website
1+ mentions
larvalign (RRID:SCR_015815) data analysis software, data or information resource, data processing software, data set, sequence analysis software, software application, software resource, software toolkit Software package including computational methods for aligning gene expression patterns from the larval brain of Drosophila melanogaster. Its method includes evaluation of the registration framework involved in template generation and mapping. drosophila melanogaster, computational method, gene expression, alignment, larval brain, larvae, template generation, mapping, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download biotools:larvalign https://bio.tools/larvalign SCR_015815 2026-09-12 12:58:31 1
Canu
 
Resource Report
Resource Website
1000+ mentions
Canu (RRID:SCR_015880) data analysis software, data processing software, sequence analysis software, software application, software resource Software for scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation. Canu is a fork of the Celera Assembler and is designed for high-noise single-molecule sequencing (such as the PacBio RS II/Sequel or Oxford Nanopore MinION). long-read, assembly, k-mer, weighting, repeat separation, adaptive, pacbio, single-molecule, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Celera assembler
National Human Genome Research Institute ;
National Science Foundation NSF IOS-1237993;
US Department of Homeland Security (DHS) HSHQDC-07-C-00020
PMID:28298431
DOI:10.1101/071282
Free, Available for download OMICS_14592, biotools:canu http://canu.readthedocs.io/en/latest/, https://bio.tools/canu, https://sources.debian.org/src/canu/ SCR_015880 2026-09-12 12:58:32 2451

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