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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) data processing software, software application, software resource, data analysis software Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-08-04 09:43:29 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) data processing software, data analysis software, software resource, sequence analysis software, software application Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks, https://bio.tools/cufflinks, https://sources.debian.org/src/cufflinks/ SCR_014597 2026-08-04 09:43:29 8838
RAST Server
 
Resource Report
Resource Website
500+ mentions
RAST Server (RRID:SCR_014606) RAST production service resource, service resource A SEED-quality automated service that annotates complete or nearly complete bacterial and archaeal genomes across the entire phylogenetic tree. RAST can also be used to analyze draft genomes. microbiome, seed, annotate, genome, bacteria, archaea, service, bio.tools is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
National Science Foundation 0850546;
NIAID contract HHSN272200900040C
PMID:18261238 Free for the scientific community, Login required biotools:theseed https://bio.tools/theseed SCR_014606 Rapid Annotation using Subsystem Technology, Rapid Annotation using Subsystem Technology Server 2026-08-04 09:43:29 907
SPEX2
 
Resource Report
Resource Website
1+ mentions
SPEX2 (RRID:SCR_014923) data processing software, data analysis software, software resource, sequence analysis software, software application Automatic software program for profiling spatial gene expression patterns from Fly embryo ISH images. It utilizes image-based genome-scale profiling of whole-body mRNA patterns. software, spatial gene expression, fly, embryo, extraction, mrna, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Carnegie Mellon University; Pennsylvania; USA
PMID:20529936 biotools:spex2 https://bio.tools/spex2 SCR_014923 2026-08-04 09:43:33 1
libRoadRunner
 
Resource Report
Resource Website
10+ mentions
libRoadRunner (RRID:SCR_014763) simulation software, software application, software resource Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support. simulation engine, simulation software, road runner, roadrunner, systems biology, synthetic biology is listed by: Debian
is listed by: OMICtools
NIGMS GM081070 DOI:10.1093/bioinformatics/btv363 Open source, Available for download OMICS_09368 https://sources.debian.org/src/libroadrunner-dev/ SCR_014763 2026-08-04 09:43:31 11
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) data processing software, data analysis software, software resource, sequence analysis software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka, https://sources.debian.org/src/prokka/, https://sources.debian.org/src/prokka/ SCR_014732 2026-08-04 09:43:31 4876
MeroX
 
Resource Report
Resource Website
50+ mentions
MeroX (RRID:SCR_014956) data processing software, data analysis software, software resource, sequence analysis software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 29,2023. Software tool for the analysis of cross-linking/mass spectrometry datasets using MS-cleavable cross-linkers. MeroX is specialized for MS/MS-cleavable cross linking reagents and identifies the specific fragmentation products of the cleavable cross links. sequence analysis software, cross linking, mass spectrometry, MS cleavage, fragmentation, cleavable cross link, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: StavroX
PMID:25261217 THIS RESOURCE IS NO LONGER IN SERVICE BioTools:MeroX, biotools:MeroX https://bio.tools/MeroX, https://bio.tools/MeroX, https://bio.tools/MeroX SCR_014956 2026-08-04 09:43:32 74
BUSCO
 
Resource Report
Resource Website
5000+ mentions
BUSCO (RRID:SCR_015008) data processing software, data analysis software, algorithm resource, software resource, software application Software tool to quantitatively measure genome assembly and annotation completeness based on evolutionarily informed expectations of gene content. genome assembly, annotation completeness, quantitative method, bio.tools is used by: rnaQUAST
is recommended by: CEGMA
is listed by: Debian
is listed by: bio.tools
is related to: CEGMA
works with: BUSCOMP
Swiss National Science Foundation ;
Marie Curie International Outgoing Fellowship
DOI:10.1093/bioinformatics/btv351 Free, Available for download, Freely available biotools:busco https://gitlab.com/ezlab/busco, https://bio.tools/busco, https://sources.debian.org/src/busco/ SCR_015008 BUSCO v2, Benchmarking Universal Single-Copy Orthologs (BUSCO), Benchmarking Universal Single-Copy Orthologs, BUSCO v1 2026-08-04 09:43:33 7284
DOGMA
 
Resource Report
Resource Website
100+ mentions
DOGMA (RRID:SCR_015060) web application, software resource Web-based annotation tool for plant chloroplasts and animal mitochondrial genomes. DOGMA allows the use of BLAST searches against a custom database, and conservation of basepairing in the secondary structure of animal mitochondrial tRNAs to identify and annotate genes. chloroplast, mitochondria, genome annotation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
PMID:15180927 Freely available biotools:DOGMA https://bio.tools/DOGMA SCR_015060 Dual Organellar GenoMe Annotator, Dual Organellar GenoMe Annotator (DOGMA) 2026-08-04 09:43:35 413
GIIRA
 
Resource Report
Resource Website
1+ mentions
GIIRA (RRID:SCR_015507) data processing software, data analysis software, software resource, sequence analysis software, software application Gene prediction method that identifies potential coding regions based on the mapping of reads from an RNA-Seq experiment. gene prediction, rna seq, coding region, potential coding region is listed by: Debian
is listed by: OMICtools
DOI:10.1093/bioinformatics/btt577 Available for download OMICS_07360 http://www.rki.de/EN/Content/Institute/DepartmentsUnits/JuniorGroups/JRG4.html, https://sources.debian.org/src/giira/ SCR_015507 2026-08-04 09:43:41 3
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) data processing software, data analysis software, software resource, sequence analysis software, software application, data visualization software Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview, https://sources.debian.org/src/seaview/ SCR_015059 2026-08-04 09:43:33 1777
LTR_Finder
 
Resource Report
Resource Website
500+ mentions
LTR_Finder (RRID:SCR_015247) analysis service resource, web service, software resource, data access protocol, production service resource, service resource Web software capable of scanning large-scale sequences for full-length LTR retrotranspsons., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Long Terminal Repeat retrotransposons, Long Terminal Repeat, retrotransposon prediction, genome sequences, LTR prediction, LTR structure prediction, DNA sequence, biotools is listed by: Debian
is listed by: bio.tools
Fudan University ;
Shanghai ;
China
PMID:17485477 THIS RESOURCE IS NO LONGER IN SERVICE SCR_020944, biotools:ltr_finder https://bio.tools/ltr_finder SCR_015247 LTR Finder 2026-08-04 09:43:37 795
SEER
 
Resource Report
Resource Website
100+ mentions
SEER (RRID:SCR_015499) data processing software, source code, data analysis software, software resource, sequence analysis software, software application Sequence element enrichment analysis tool to perform pan-genome-wide association studies in bacteria. bacterial genome association, sequence element enrichment analysis, kmer enrichment analysis is listed by: Debian
is listed by: OMICtools
is hosted by: GitHub
DOI:10.1038/ncomms12797
DOI:10.1101/038463
Available for download OMICS_21699 https://sources.debian.org/src/seer/ SCR_015499 2026-08-04 09:43:41 463
primers4clades
 
Resource Report
Resource Website
1+ mentions
primers4clades (RRID:SCR_015714) web application, software resource Web application for the design of PCR primers for cross-species amplification of novel sequences from metagenomic DNA or from uncharacterized organisms belonging to user-specified phylogenetic lineages. It implements an extended CODEHOP strategy and evaluates thermodynamic properties of the oligonucleotide pairs. pcr primer, metagenomic dna, phylogenetic lineage, primer, clade, bio.tools is listed by: Debian
is listed by: bio.tools
DGAPA IN201806-2;
CONACyT-Mexico P1-60071;
CSIC 200720I038
PMID:19465390 Freely available, Free for academic use, Tutorial available biotools:primers4clades http://maya.ccg.unam.mx/primers4clades, https://bio.tools/primers4clades SCR_015714 2026-08-04 09:43:42 2
clustergrammer
 
Resource Report
Resource Website
10+ mentions
clustergrammer (RRID:SCR_015681) data visualization tool, software tool Clustergrammer is a web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable hierarchically clustered heatmaps. Clustergrammer enables intuitive exploration of high-dimensional data and has several optional biology-specific features. bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/sdata.2017.151 biotools:clustergrammer https://bio.tools/clustergrammer SCR_015681 2026-08-04 09:43:43 41
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) data processing software, source code, data analysis software, software resource, software application Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-08-04 09:43:42 1749
BSVF
 
Resource Report
Resource Website
1+ mentions
BSVF (RRID:SCR_015727) BSVF data processing software, source code, data analysis software, software resource, sequence analysis software, software application Software code for bisulfite sequencing virus integration. This finder is for directional libraries only and does not support PBAT and indirectional libraries. virus integration, sequencing analysis, virus assembly, integration, bisulfite, bio.tools is listed by: bio.tools
is listed by: Debian
Open source biotools:bs-virus-finder https://bio.tools/bs-virus-finder SCR_015727 BSVF: Bisulfite Sequencing Virus integration Finder, Bisulfite Sequencing Virus integration Finder 2026-08-04 09:43:43 1
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) systems interoperability software, software resource, software application, web application, electronic laboratory notebook Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-08-04 09:43:43 3
DISEASES
 
Resource Report
Resource Website
500+ mentions
DISEASES (RRID:SCR_015664) database, data or information resource Database that integrates evidence on disease-gene associations from automatic text mining, manually curated literature, cancer mutation data, and genome-wide association studies. It also assigns confidence scores that facilitate comparison of the different types and sources of evidence. disease, gene, disease-gene association, text-mining, , bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation Center for Protein Research NNF14CC0001;
European Union Seventh Framework Programme n259348
PMID:25484339 biotools:diseases https://bio.tools/diseases SCR_015664 2026-08-04 09:43:43 627
TISSUES
 
Resource Report
Resource Website
10+ mentions
TISSUES (RRID:SCR_015665) web application, software resource, database, data or information resource Database that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. It maps all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unifies it by assigning confidence scores that facilitate comparison of the different types and sources of evidence. tissue expression, proteomic, transcriptomic, text-mining, brenda tissue ontology, protein identifier, bio.tools uses: BRENDA Tissue and Enzyme Source Ontology
is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation NNF14CC0001;
NCI U54 CA189205-01;
CSIRO’s OCE Science Leader program
PMID:26157623 Freely available, Free, Available for download biotools:tissues https://bio.tools/tissues SCR_015665 TISSUES: Tissue Expression Database, Tissue Expression Database 2026-08-04 09:43:42 42

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