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http://en.wikibooks.org/wiki/Next_Generation_Sequencing
The Need for an Up-To-Date Synthesis of Next Generation Sequencing Know-How.
Proper citation: Next Generation Sequencing WikiBook (RRID:SCR_011993) Copy
http://tfclass.bioinf.med.uni-goettingen.de/tfclass
Database that classifies human transcription factors based on the characteristics of their DNA-binding domains. It comprises six levels (superclasses, classes, families, subfamilies, genera and factor species), two of which are optional (subfamilies and factor species). The full classification can also be obtained as html document and as ontology in obo-format., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: TFClass (RRID:SCR_012018) Copy
Catalog of published genome-wide association studies. Genome-wide set of genetic variants in different individuals to see if any variant is associated with trait and disease. Database of genome-wide association study (GWAS) publications including only those attempting to assay single nucleotide polymorphisms (SNPs). Publications are organized from most to least recent date of publication. Studies are identified through weekly PubMed literature searches, daily NIH-distributed compilations of news and media reports, and occasional comparisons with an existing database of GWAS literature (HuGE Navigator). Works with HANCESTRO ancestry representation.
Proper citation: GWAS: Catalog of Published Genome-Wide Association Studies (RRID:SCR_012745) Copy
http://www.aasld.org/Pages/Default.aspx
A non-profit organization of scientists and healthcare professionals committed to preventing and curing liver disease, which runs three journals and an annual meeting. Its mission is to Advance the Science and Practice of Hepatology, Liver Transplantation and Hepatobiliary Surgery, Thereby Promoting Liver Health and Optimal Care of Patients with Liver and Biliary Tract Diseases. AASLD was founded in 1950 by a small group of leading liver specialists (including Hans Popper, Leon Schiff, Fred Hoffbauer, Cecil Watson, Jesse Bollman, and Sheila Sherlock, to name a few) to bring together those who had contributed to the field of hepatology. AASLD has grown to an international society responsible for all aspects of hepatology, and our annual meeting, The Liver Meeting, has grown in attendance from 12 to over 7,000 physicians, surgeons, researchers, and allied health professionals from around the world. AASLD sponsors two to four Single Topic Conferences each year in clinical, basic, hepatitis, or pediatric hepatology. Our two monthly journals, HEPATOLOGY and Liver Transplantation, provide the latest research findings for hepatology and surgery of the liver. AASLD''s membership includes ALL professionals dedicated to hepatobiliary discoveries and patient care. Mentoring, the sharing of knowledge, and dedication to professional growth and development are among the core values of AASLD and its members.
Proper citation: AASLD - American Association for the Study of Liver Diseases (RRID:SCR_012900) Copy
http://www.cdc.gov/nceh/tracking
The goal of environmental public health tracking is to protect communities by providing information to federal, state, and local agencies. These agencies, in turn, will use this information to plan, apply, and evaluate public health actions to prevent and control environmentally related diseases. Environmental public health tracking is the ongoing collection, integration, analysis, and interpretation of data about the following factors: :- Environmental hazards :- Exposure to environmental hazards :- Health effects potentially related to exposure to environmental hazards CDC''s goal is to develop a tracking system that integrates data about environmental hazards and exposures with data about diseases that are possibly linked to the environment. This system will allow federal, state, and local agencies, and others to do the following: :- monitor and distribute information about environmental hazards and disease trends :- advance research on possible linkages between environmental hazards and disease :- develop, implement, and evaluate regulatory and public health actions to prevent or control environment-related diseases. Planning for an environmental public health tracking network is an important priority for CDC because of the opportunity it provides to address some of the most challenging problems facing local, state, and national public health leaders. From the outset, this activity has involved substantial collaboration between CDC and its public health and environmental partners (e.g., see the memorandum of understanding between HHS/CDC and the Environmental Protection Agency). Sponsors: This resource is supported by the Center for Disease Control and Prevention. Keywords: Environment, Public, Health, Disease, Analysis, Integration, Data, Hazard, Health, Prevention,
Proper citation: National Environmental Public Health Tracking Program (RRID:SCR_012832) Copy
A next-generation stand-alone genome browser and editor initiated in the BSB group at VIB and currently developed at Broad Institute.
Proper citation: GenomeView (RRID:SCR_012968) Copy
http://www.ucdenver.edu/academics/colleges/medicalschool/centers/tastesmell/Pages/software.aspx
:GLOM MAP was written for MATLAB, it works equally as well on the PC as on the MAC. GLOM MAP consists of two components: 1. OBS can be used to map the location of glomeruli in transverse sections of the olfactory bulb. 2. GDB can be used to transform the OBS data and to analyze the collected glomerular activity data. This data can be scored and mapped in the radial and anterio-posterior dimensions as discussed in Salcedo et al, 2005. :
Proper citation: GLOM MAP is a toolbox written for the MATLAB development enviroment (RRID:SCR_013274) Copy
http://www.cochrane.org/reviews/clibintro.htm
Contains data to inform healthcare decision-making from Cochrane and other systematic reviews, clinical trials, and more. Cochrane reviews bring you the combined results of the worlds best medical research studies, and are recognized as the gold standard in evidence-based health care. Consists of a regularly updated collection of evidence-based medicine databases, including The Cochrane Database of Systematic Reviews. This database includes systematic reviews of healthcare interventions that are produced and disseminated by The Cochrane Collaboration. It is published on a monthly basis and made available both on CD-ROM and the Internet. The review abstracts are available to browse and search free of charge on this website. The Cochrane Library Users'' Group (CLUG) provides a forum for discussion of usability, readability, searchability, and formatting issues related to the use of The Cochrane Library. The Cochrane Collaboration is an international not-for-profit and independent organization, dedicated to making up-to-date, accurate information about the effects of healthcare readily available worldwide. Funded by John Wiley and Sons Limited. The individual entities of The Cochrane Collaboration are funded by a large variety of governmental, institutional and private funding sources, and are bound by organisation-wide policy limiting uses of funds from corporate sponsors.
Proper citation: Cochrane Library (RRID:SCR_013000) Copy
http://www.dkfz.de/en/epidemiologie-krebserkrankungen/software/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software program that performs estimation of power and sample sizes required to detect genetic and environmental main, as well as gene-environment interaction (GxE) effects in indirect matched case-control studies (1:1 matching). When the hypothesis of GxE is tested, power/sample size will be estimated for the detection of GxE, as well as for the detection of genetic and environmental marginal effects. Furthermore, power estimation is implemented for the joint test of genetic marginal and GxE effects (Kraft P et al., 2007). Power and sample size estimations are based on Gauderman''s (2002) asymptotic approach for power and sample size estimations in direct studies of GxE. Hardy-Weinberg equilibrium and independence of genotypes and environmental exposures in the population are assumed. The estimates are based on genotypic codes (G=1 (G=0) for individuals who carry a (non-) risk genotype), which depend on the mode of inheritance (dominant, recessive, or multiplicative). A conditional logistic regression approach is used, which employs a likelihood-ratio test with respect to a biallelic candidate SNP, a binary environmental factor (E=1 (E=0) in (un)exposed individuals), and the interaction between these components. (entry from Genetic Analysis Software)
Proper citation: PIAGE (RRID:SCR_013124) Copy
http://www.ebi.ac.uk/thornton-srv/databases/CSA/
The Catalytic Site Atlas (CSA) is a database documenting enzyme active sites and catalytic residues in enzymes of 3D structure. We defined a classification of catalytic residues which includes only those residues thought to be directly involved in some aspect of the reaction catalyzed by an enzyme. The CSA contains 2 types of entry: 1. Original hand-annotated entries, derived from the primary literature. References for these entries are given. 2. Homologous entries, found by PSI-BLAST alignment (using an e value cut-off of 0.00005) to one of the original entries. The equivalent residues, which align in sequence to the catalytic residues found in the original entry are documented. Access to the CSA is via PDB code, SWISS-PROT entry or E.C. number. Accessing via PDB code takes you straight to the CSA entry for that PDB, while accessing via SWISS-PROT or E.C. number gives a list of all PDB codes for structures assigned that particular SWISS-PROT identifier or E.C. number. Structures with entries in the CSA are given as hyperlinks. Each CSA entry lists the catalytic residues found in that entry, using PDB residue numbering. Each site is also marked with an evidence tag, which is either Literature reference or PSI-BLAST hit. If the entry is a PSI-BLAST hit you can follow the link to the original entry. You may download the CSA. JESS, an algorithm for constraint-based structural template matching and its application to 3D templates used by the CSA, is available for download.
Proper citation: CSA - Catalytic Site Atlas (RRID:SCR_013099) Copy
http://www.functionalglycomics.org
This Gateway is a collaboration between the Consortium for Functional Glycomics (CFG) and Nature Publishing Group (NPG), providing a comprehensive resource for functional glycomics research. Use this site to stay up-to-date on glycomics news, request CFG resources, and search databases of glycan-binding proteins, glycan structures, and glycosyltransferases. The Functional Glycomics Update provides a one-stop overview of the latest research in glycobiology for specialists and non-specialists alike. It is updated monthly to bring you the latest news and selected highlights from Nature journals. In addition, it will provide two featured articles a month on the most relevant advances in the field published in NPG and other top journals. By collating new articles into a key worded research library, we hope to provide a continuously updated and broad overview of the field. Sponsor. The CFG is a large international research initiative funded by NIGMS to elucidate the roles of carbohydrate-protein interactions in cell communication at the cell surface.
Proper citation: Functional Glycomics Research (RRID:SCR_013337) Copy
http://www.ritsumei.ac.jp/~akitaoka/index-e.html
This portal describes Professor Kitaoka Akiyoshi''s research in the science of visual illusions. Working as an associate professor at the Ritsumeiken University, Department of Psychology, he is one of the few researchers in Japan to be actively researching in this field of study. Professor Kitaoka defines an illusion as a misperception of a real object, adding that defining what is real is a difficult task that depends on recognition and epistemology. An illusion is formed when the perceived characteristics of the object differ from the physical characteristics. Professor Kitaoka first started studying visual illusions when working at the Tokyo Metropolitan Institute for Neuroscience, before coming to RU. He currently researches geometrical, color, lightness, and motion illusions and visual completion, and has become a prominent expert in the field, publishing a wide range of articles on the subject as well as the popular books Trick Eyes, Trick Eyes 2, Trick Eyes Graphics, and the Handbook of the Science of Illusion. To create his illusions, Professor Kitaoka uses graphic design software such as CorelDRAW, Adobe Illustrator, and the drawing software included in Microsoft Word in addition to making use of programming languages like Borland Delphi (Pascal). All of the images set out to test hypotheses that serve to advance his study of illusions and their applications for other visual functions. The goal of his research is to test visual mechanisms through visual illusions.
Proper citation: Akiyoshis illusion pages (RRID:SCR_013187) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 2, 2022. Much of the current effort in functional genomics, and our understanding of the biology of human disease, is underpinned by informatics infrastructures served by the scattered collection of relevant databases which exists in Europe. This infrastructure is essential for the support of a European Research Area in mouse functional genomics. CASIMIR, a coordination action of the 6th Framework Programme of the European Commission, will focus on co-ordination and integration of databases set up in support of FP5 and FP6 projects containing experimental data, including sequences, and material resources such as biological collections, relevant to the use of the mouse as a model organism for human disease. Interoperability of disseminated databases potentially provides enormous synergy in the provision, integration and analysis of a wide range of data with concomitant added value for research projects. Having set standards and benchmarks the proposed action will then reach out to co-ordinate other European and International databases and consult with the Community. EU FlagThe CASIMIR project is funded by the European Commission within its FP6 Programme, under the thematic area Life sciences, genomics and biotechnology for health, contract number LSHG-CT-2006-037811
Proper citation: Coordination and sustainability of international mouse informatics resources (RRID:SCR_013345) Copy
The incidence of Creutzfeldt-Jakob disease (CJD) is monitored in the UK by the National CJD Surveillance Unit (NCJDSU) based at the Western General Hospital in Edinburgh, Scotland. The Unit brings together a team of clinical neurologists, neuropathologists and scientists specialising in the investigation of this disease. This document is intended to summarise the research in progress at the NCJDSU and also provide some background information about CJD and other human spongiform encephalopathies. We have also provided some links to other resources and contrary points of view available on the Web.
Proper citation: NCJDSU (RRID:SCR_013183) Copy
http://wellness.wikispaces.com/
Wellness Wiki is offered to help clarify the complex problems plaguing the U.S. healthcare system and develop sustainable ways to improve the health and well-being of all people. This virtual encyclopedia of the healthcare crisis and potential remedies welcomes your comments! The Wellness Wiki Book (Understanding & Curing American Healthcare: A Wise Way to Better Outcomes and Lower Costs) is available for purchase as a softcover book or pdf download. Table of contents: *Introduction & Executive Summary *Defining the Problem *Examining Three Proposed Solutions *Introducing a New Solution - Overview and Benefits, Wellness-Plus Solution Tactics, Barriers and Drivers to Implementing the Wellness-Plus Solution *Conclusion & Epilogue *Appendix *Wellness Model Technology Blueprint
Proper citation: Wellness Wiki (RRID:SCR_004957) Copy
https://knightadrc.wustl.edu/center-events/
Videos of Knight ADRC related events for educational and informational purposes. A link to additional Center produced media is provided to access the Knight ADRC YouTube Channel. Videos are in HTML5 mp4 format and are available in 1080p or 4K resolution.
Proper citation: WU Knight ADRC Multimedia Presentations (RRID:SCR_005147) Copy
Tropical Botanic Garden & Research Institute (TBGRI) is an autonomous Institute established by the Government of Kerala on 17th November 1979 and registered on 23rd November 1979 under the Travancore-Cochin Literary, Scientific and Charitable Societies Registration Act, 1955. It functions under the umbrella of the Science, Technology and Environment Department, Government of Kerala. Prof. A. Abraham, a visionary and a great Botanist, conceived the idea of establishing a Botanic Garden and Research Institute to study and conserve the rare and vanishing wild plant genetic resources of the country. Kinded by the spirit of his concept, the Government of Kerala took a far sighted decision resulting in the establishment of Tropical Botanic Garden & Research Institute (TBGRI) as an autonomous organization at Thiruvananthapuram, the capital City of Kerala. In the beginning, the Institute functioned at Thiruvananthapuram city on a rented duplex building. Thanks to the Forests & Wildlife Department, the land for establishment of the garden was allotted in 1983 and the foundation stone was laid on 27th May 1983 by the then Chief Minister, Shri K. Karunakaran. The then Education Minister, the late C. H. Mohammed Koya laid the foundation stone for the construction of the Visiting Scientists'' Guest House. The meeting was presided over by the Minister for Forests, Shri K. P. Noorudeen. With the recruitment of a skeletal scientific and technical staff, the Institute made a modest beginning. Biotechnology and Taxonomy were the two subjects considered to have immediate relevance to the development of the garden. While taxonomists prepared a flora of the garden documenting the native plant wealth before mass introduction and face lift which subsequently followed, the bio-technologists mass multiplied plants of commercial importance, especially orchids for cultivation and distribution to the public. The Royal Botanic Gardens (RBG), Kew played an exemplary and significant role in shaping and design of garden lay out of TBGRI in its formative stages. RBG, Kew not only lent its best men to train our technical staff in gardening and landscaping but also generously supplied books and living plants as gifts to enrich the respective collections. Undoubtedly, the continuing support of RBG, Kew is of special mention in the development of the Garden.
Proper citation: Tropical Botanic Garden and Research Institute (RRID:SCR_005162) Copy
http://noble.gs.washington.edu/proj/percolator/
Percolator post-processes the results of a shotgun proteomics database search program, re-ranking peptide-spectrum matches so that the top of the list is enriched for correct matches. Shotgun proteomics uses liquid chromatography-tandem mass spectrometry to identify proteins in complex biological samples. We describe an algorithm, called Percolator, for improving the rate of peptide identifications from a collection of tandem mass spectra. Percolator uses semi-supervised machine learning to discriminate between correct and decoy spectrum identifications, correctly assigning peptides to 17% more spectra from a tryptic dataset and up to 77% more spectra from non-tryptic digests, relative to a fully supervised approach. The yeast-01 data is available in tab delimetered format. The SEQUEST parameter file and target database for the yeast and worm data are also available.
Proper citation: Percolator: Semi-supervised learning for peptide identification from shotgun proteomics datasets (RRID:SCR_005040) Copy
http://bioinformatics.knowledgeblog.org/
Series of tutorial material covering a broad selection of topics in bioinformatics. Categories include: Bioinformatics APIs, Data integration, Events, Grid and Cloud Computing, Metabolic modelling, Reviews, Software Comparisons, Statistics, Systems Biology, Transcriptomics, Tutorials.
Proper citation: Bioinformatics Knowledgeblog (RRID:SCR_005379) Copy
https://www.har.mrc.ac.uk/about/mammalian-genetics-unit
It is now widely known that animals share many genes with humans and can suffer from the same diseases, for example diabetes or deafness. Investigating these diseases in animals can provide vital leads to understanding both their causes and ways to treat them in humans. This approach to medical research lies at the heart of work at the MRC Mammalian Genetics Unit (MGU) at Harwell in Oxfordshire. In 1995 the MRC Radiobiology Unit was reconstituted to form two new units, the Radiation and Genome Stability Unit and the MGU. These opened in January 1996, together with the UK Mouse Genome Centre which is now part of MGU, making MRC Harwell a unique campus for multi-disciplinary genetics research. Since MGU's Director Steve Brown took the reins in 1996, the unit has dramatically expanded its scientific scope and increased its personnel from 40 to over 100. It now has 13 research programs encompassing molecular genetics, genomics, genetic manipulation and data analysis at all levels, from single genes to the whole genome. With a combination of cutting-edge facilities and expertise unrivaled in Europe, MGU Harwell has become firmly established as one of the world's leading academic centres for mouse genetics.
Proper citation: MRC Mammalian Genetics Unit (RRID:SCR_005378) Copy
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