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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Drug Related Gene Database
 
Resource Report
Resource Website
1+ mentions
Drug Related Gene Database (RRID:SCR_003330) DRG data or information resource, database Gene expression data from published journal articles that test hypotheses relevant to neuroscience of addiction and addictive behavior. Data types include effects of particular drug, strain, or knock out on particular gene, in particular anatomical region. Focuses on gene expression data and exposes data from investigations using DNA microarrays, polymerase chain reaction, immunohistochemistry and in-situ hybridizations. Data are available for query through NIF interface.Data submissions are welcome. drug of abuse, gene expression, brain region, brain, american recovery and reinvestment act, brain, dna microarray, microarray, addiction uses: PubMed
is listed by: NIF Data Federation
is related to: Integrated Manually Extracted Annotation
has parent organization: Neuroscience Information Framework
NIDA Free, Freely available nif-0000-37443 https://confluence.crbs.ucsd.edu/login.action?os_destination=%2Fpages%2Fviewpage.action%3FspaceKey%3DNIF%26title%3DDRG&permissionViolation=true SCR_003330 DRG Database, Drug Dependent Gene Database 2026-09-19 12:56:39 2
Enhancer Trap Line Browser
 
Resource Report
Resource Website
Enhancer Trap Line Browser (RRID:SCR_003592) Enhancer Trap Line Browser atlas, data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 6, 2023. Database and atlas of transgenic mouse lines that are generated by random insertion of enhancer trap probes. The trapped lines have highly restricted expression of tet transcription activator (some lines also have Cre DNA recombinase), which enables genetic manipulations in specific cell types. sagittal, coronal, gene, image, enhancer trap, piggybac transposon, probe, tet enahcer trap is related to: UCSC Genome Browser
is related to: Mouse Genome Informatics (MGI)
is related to: Allen Mouse Brain Reference Atlas
has parent organization: Brandeis University; Massachusetts; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_157737 SCR_003592 2026-09-19 12:56:40 0
FIDEA
 
Resource Report
Resource Website
1+ mentions
FIDEA (RRID:SCR_004187) FIDEA analysis service resource, data analysis service, production service resource, service resource A web server for the functional interpretation of differential expression analysis. It can: * Calculate overrepresentation statistics using KEGG, Interpro, Gene Ontology Molecular Function, Gene Ontology Biological Process, Gene Ontology Cellular Component and GoSlim classifications; * Analyze down-regulated and up-regulated DE genes separately or together as a single set; * Provide interactive graphs and tables that can be modified on the fly according to user defined parameters; the user can set a fold change filter and interactively see the effects on the gene set under examination; * Output publication-ready plot of the graph; * Compare the results of several experiments in any combination. is listed by: OMICtools
has parent organization: Sapienza University of Rome; Rome; Italy
PMID:23754850 Public, Free, Acknowledgement requested OMICS_01539 SCR_004187 Functional Interpretation of Differential Expression Analysis 2026-09-19 12:56:42 9
Pain Genes database
 
Resource Report
Resource Website
10+ mentions
Pain Genes database (RRID:SCR_004771) PainGenesdb data or information resource, database Database of genes regulated by pain derived from published manuscripts describing results of pain-relevant knockout studies. The database has two levels of exploration: across-gene and within-gene. The across-gene level, the PainGenesdbSelector, is encountered first. All genes in the database can be accessed and sorted by their gene name, protein name, common names and acronyms, or genomic position (by navigating a graphic representation of the mouse genome). The gene and protein names can be selected from an alphabetical list, or by typing a text string into a search box. knock out mouse, pain sensation, mice, mutant, knockout, gene, genome, protein has parent organization: McGill University; Montreal; Canada Pain Louise Edwards Foundation PMID:17574758 nlx_77039, r3d100012129 https://doi.org/10.17616/R3WP95 SCR_004771 PainGenes DB 2026-09-19 12:56:46 16
Information Hyperlinked Over Proteins
 
Resource Report
Resource Website
10+ mentions
Information Hyperlinked Over Proteins (RRID:SCR_004829) iHOP data or information resource, database, service resource Information system that provides a network of concurring genes and proteins extends through the scientific literature touching on phenotypes, pathologies and gene function. It provides this network as a natural way of accessing millions of PubMed abstracts. By using genes and proteins as hyperlinks between sentences and abstracts, the information in PubMed can be converted into one navigable resource, bringing all advantages of the internet to scientific literature research. Moreover, this literature network can be superimposed on experimental interaction data (e.g., yeast-two hybrid data from Drosophila melanogaster and Caenorhabditis elegans) to make possible a simultaneous analysis of new and existing knowledge. The network contains half a million sentences and 30,000 different genes from humans, mice, D. melanogaster, C. elegans, zebrafish, Arabidopsis thaliana, yeast and Escherichia coli. phenotype, gene, protein, interaction, pathology, physiology, gene network, network, literature, gene function, text-mining, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: PubMed
has parent organization: Autonomous University of Madrid; Madrid; Spain
European Union IST-2001- 32688;
European Union QLRT-2001-00015
PMID:15226743 Creative Commons Attribution-NoDerivs License, Works v3 biotools:ihop, nif-0000-00232, OMICS_01185 https://bio.tools/ihop SCR_004829 iHOP - Information Hyperlinked over Proteins 2026-09-19 12:56:47 24
mouseMAP
 
Resource Report
Resource Website
mouseMAP (RRID:SCR_004784) MouseMAP analysis service resource, data analysis service, production service resource, service resource In collaboration with several research groups at Jackson Laboratory, we mapped the tissue-specific functional relationship networks in the laboratory mouse by simulating the natural tissue specificity realized by differential protein expression between tissues. MouseMAP is an interface that allows browsing networks of different tissues and the comparison between them. The current version of MouseMAP includes one global network as an extension of mouseNET (http://mousenet.princeton.edu) and 107 tissue-specific networks organized into 15 different major body systems. The interface has the following features (their usage are detailed in Help and FAQ page): 1. Single graph query with one or multiple genes of interests. 2. Expansion/shrinking of query results through edge or node cutoffs. 3. Comparison of local networks between different tissues. 4. Dynamic generation of figure legend to facilitate manuscript writing. network, visualization, mouse, gene is related to: MouseNET
has parent organization: Princeton University; New Jersey; USA
nlx_143914 SCR_004784 mouseMAP: Tissue-specific functional networks for the laboratory mouse 2026-09-19 12:56:46 0
MethylomeDB
 
Resource Report
Resource Website
1+ mentions
MethylomeDB (RRID:SCR_005583) MethylomeDB data or information resource, database A database containing genome-wide brain DNA methylation profiles for human and mouse brains. The DNA methylation profiles were generated by Methylation Mapping Analysis by Paired-end Sequencing (Methyl-MAPS) method and analyzed by Methyl-Analyzer software package. The methylation profiles cover over 80% CpG dinucleotides in human and mouse brains in single-CpG resolution. The integrated genome browser (modified from UCSC Genome Browser allows users to browse DNA methylation profiles in specific genomic loci, to search specific methylation patterns, and to compare methylation patterns between individual samples. Two species were included in the Brain Methylome Database: human and mouse. Human postmortem brain samples were obtained from three distinct cortical regions, i.e., dorsal lateral prefrontal cortex (dlPFC), ventral prefrontal cortex (vPFC), and auditory cortex (AC). Human samples were selected from our postmortem brain collection with extensive neuropathological and psychopathological data, as well as brain toxicology reports. The Department of Psychiatry of Columbia University and the New York State Psychiatric Institute have assembled this brain collection, where a validated psychological autopsy method is used to generate Axis I and II DSM IV diagnoses and data are obtained on developmental history, history of psychiatric illness and treatment, and family history for each subject. The mouse sample (strain 129S6/SvEv) DNA was collected from the entire left cerebral hemisphere. The three human brain regions were selected because they have been implicated in the neuropathology of depression and schizophrenia. Within each cortical region, both disease and non-psychiatric samples have been profiled (matching subjects by age and sex in each group). Such careful matching of subjects allows one to perform a wide range of queries with the ability to characterize methylation features in non-psychiatric controls, as well as detect differentially methylated domains or features between disease and non-psychiatric samples. A total of 14 non-psychiatric, 9 schizophrenic, and 6 depression methylation profiles are included in the database. brain, dna methylation, dorsal lateral prefrontal cortex, ventral prefrontal cortex, auditory cortex, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Columbia University; New York; USA
NIH ;
NHGRI HG002915;
NIMH MH074118
PMID:22140101 OMICS_01843, biotools:methylomedb, nlx_146210 https://bio.tools/methylomedb SCR_005583 MethylomeDB - the Brain Methylome Database, Brain Methylome Database 2026-09-19 12:56:52 1
High Resolution Mouse Brain Atlas
 
Resource Report
Resource Website
10+ mentions
High Resolution Mouse Brain Atlas (RRID:SCR_006063) High Resolution Mouse Brain Atlas atlas, data or information resource 2D mouse brain atlas of high quality coronal Nissl- and myelin-stained sections with labels, 3D images of hippocampal formation and limited other brain structures. The data for this digital atlas are based on the Atlas of the Mouse Brain and Spinal Cord, authored by Richard L. Sidman, Jay. B. Angevine and Elizabeth Taber Pierce, published as a hard cover book by Harvard University Press in 1971 and currently out of print. C57BL/6J strain adult specimens were used in creating the atlas. adult mouse, hippocampal formation, image, leaf lumina camera, mouse, normal, nuclei of the limbic thalamus, c57bl/6, nissel, myelin, neuroanatomy, olfactory bulb, frontal pole, pyriform cortex, septo-striatal, septo-diencephalic, rostral diencephalon, caudal diencephalon, rostral cerebellum, caudal cerebellum, medula, spinal cord, diencephalon, cerebellum, mesencephalon has parent organization: Harvard University; Cambridge; United States Human Brain Project ;
NINDS RO1 NS36041
nif-0000-00087 SCR_006063 2026-09-19 12:56:55 28
Unified Human Interactome
 
Resource Report
Resource Website
10+ mentions
Unified Human Interactome (RRID:SCR_005805) UniHI data or information resource, database A database of human molecular interaction networks that integrates human protein-protein and transcriptional regulatory interactions from 15 distinct resources and aims to give direct and easy access to the integrated data set and to enable users to perform network-based investigations. The database includes tools (i) to search for molecular interaction partners of query genes or proteins in the integrated dataset, (ii) to inspect the origin, evidence and functional annotation of retrieved proteins and interactions, (iii) to visualize and adjust the resulting interaction network, (iv) to filter interactions based on method of derivation, evidence and type of experiment as well as based on gene expression data or gene lists and (v) to analyze the functional composition of interaction networks. molecular interaction network, interactome, protein, protein interaction network, protein interaction, pathway, function, visualization, protein-protein interaction, transcriptional regulatory interaction, network is listed by: OMICtools
has parent organization: University of Algarve; Faro; Portugal
PMID:24214987
PMID:22218860
PMID:18984619
PMID:17158159
Public, Non-commercial OMICS_01911, nif-0000-03609 http://www.mdc-berlin.de/unihi SCR_005805 2026-09-19 12:56:54 20
FuncAssociate: The Gene Set Functionator
 
Resource Report
Resource Website
10+ mentions
FuncAssociate: The Gene Set Functionator (RRID:SCR_005768) FuncAssociate analysis service resource, data analysis service, production service resource, service resource A web-based tool that accepts as input a list of genes, and returns a list of GO attributes that are over- (or under-) represented among the genes in the input list. Only those over- (or under-) representations that are statistically significant, after correcting for multiple hypotheses testing, are reported. Currently 37 organisms are supported. In addition to the input list of genes, users may specify a) whether this list should be regarded as ordered or unordered; b) the universe of genes to be considered by FuncAssociate; c) whether to report over-, or under-represented attributes, or both; and d) the p-value cutoff. A new version of FuncAssociate supports a wider range of naming schemes for input genes, and uses more frequently updated GO associations. However, some features of the original version, such as sorting by LOD or the option to see the gene-attribute table, are not yet implemented. Platform: Online tool gene, gene ontology, statistical analysis, web service, bio.tools is listed by: Gene Ontology Tools
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: Roth Laboratory
NIH ;
Canadian Institute for Advanced Research ;
NINDS NS054052;
NINDS NS035611;
NHLBI HL081341;
NHGRI HG0017115;
NHGRI HG004233;
NHGRI HG003224
PMID:19717575
PMID:14668247
Free for academic use, Acknowledgement requested biotools:funcassociate, OMICS_02264, nlx_149233 http://llama.mshri.on.ca/cgi/func/funcassociate, https://bio.tools/funcassociate SCR_005768 2026-09-19 12:56:53 36
ADGO
 
Resource Report
Resource Website
1+ mentions
ADGO (RRID:SCR_006343) ADGO analysis service resource, data analysis service, production service resource, service resource A web-based tool that provides composite interpretations for microarray data comparing two sample groups as well as lists of genes from diverse sources of biological information. It provides multiple gene set analysis methods for microarray inputs as well as enrichment analyses for lists of genes. It screens redundant composite annotations when generating and prioritizing them. It also incorporates union and subtracted sets as well as intersection sets. Users can upload their gene sets (e.g. predicted miRNA targets) to generate and analyze new composite sets. microarray, gene, annotation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21624890 Acknowledgement requested OMICS_02229, biotools:adgo https://bio.tools/adgo SCR_006343 2026-09-19 12:56:57 3
Recombinase (cre) Activity
 
Resource Report
Resource Website
10+ mentions
Recombinase (cre) Activity (RRID:SCR_006585) Recombinase Activity data or information resource, database Curated data about all recombinase-containing transgenes and knock-ins developed in mice providing a comprehensive resource delineating known activity patterns and allows users to find relevant mouse resources for their studies. cre, recombinase, transgene, knock-in, allele, expression, activity pattern, mutagenesis, promoter, driver, image, tissue, specificity assay is related to: International Mouse Strain Resource
is related to: CREATE
is related to: JAX Cre Repository
is related to: Allen Institute for Brain Science
is related to: CRE Driver Network
is related to: Pleiades Promoter Project: Genomic Resources Advancing Therapies for Brain Disorders
is related to: EUCOMMTOOLS
has parent organization: Mouse Genome Informatics (MGI)
European Union HEALTH-F4-2009-223487;
NCRR RR03 2656;
NICHD HD062499
SCR_017520, nlx_152803 http://www.creportal.org/ SCR_006585 Cre Portal 2026-09-19 12:56:59 22
Tuberculosis Database
 
Resource Report
Resource Website
50+ mentions
Tuberculosis Database (RRID:SCR_006619) TBDB data or information resource, database Database providing integrated access to genome sequence, expression data and literature curation for Tuberculosis (TB) that houses genome assemblies for numerous strains of Mycobacterium tuberculosis (MTB) as well assemblies for over 20 strains related to MTB and useful for comparative analysis. TBDB stores pre- and post-publication gene-expression data from M. tuberculosis and its close relatives, including over 3000 MTB microarrays, 95 RT-PCR datasets, 2700 microarrays for human and mouse TB related experiments, and 260 arrays for Streptomyces coelicolor. (July 2010) To enable wide use of these data, TBDB provides a suite of tools for searching, browsing, analyzing, and downloading the data. genomic, protein, blast, genome, gene, systems biology, gene expression, microarray, comparative analysis, regulatory network, metabolic network, epitope, expression profile, rt-pcr, gene regulation, genome browser, FASEB list is listed by: re3data.org
is related to: SMD
is related to: BioCyc
has parent organization: Broad Institute
has parent organization: Stanford University School of Medicine; California; USA
Tuberculosis Bill and Melinda Gates Foundation PMID:20488753
PMID:18835847
Acknowledgement requested, Public, (Published data) nif-0000-03537, r3d100010930 https://doi.org/10.17616/R39G8F SCR_006619 TB Database, TBDatabase 2026-09-19 12:56:59 64
Integrated Gene-Disease Interaction
 
Resource Report
Resource Website
Integrated Gene-Disease Interaction (RRID:SCR_006173) data or information resource, database Virtual database currently indexing interaction between genes and diseases from Online Mendelian Inheritance in Man (OMIM) and Comparative Toxicogenomics Database (CTD). gene, phenotype, disease, interaction, integrated, database is used by: NIF Data Federation
is related to: OMIM
is related to: Comparative Toxicogenomics Database (CTD)
has parent organization: Integrated
NIDA ;
NIH Blueprint for Neuroscience Research
Data are licensed by their respective owners, Use and distribution is subject to the Terms of Use by the original resource nlx_151674 https://legacy.neuinfo.org/mynif/search.php?q=*&t=indexable&list=cover&nif=nlx_154697-7 http://neuinfo.org/nif/nifgwt.html?query=nlx_151674, https://www.neuinfo.org/mynif/search.php?q=*&t=indexable&nif=nlx_151674-1, https://neuinfo.org/mynif/search.php?q=*&t=indexable&list=cover&nif=nlx_154697-7 SCR_006173 Gene-Disease Interaction, NIF Integrated Gene-Disease Interaction, Integrated GDI, NIF Integrated Gene-Disease Interaction View, NIF Gene-Disease Interaction, Integrated Gene-Disease Interaction View 2026-09-19 12:56:56 0
BioGPS: The Gene Portal Hub
 
Resource Report
Resource Website
500+ mentions
BioGPS: The Gene Portal Hub (RRID:SCR_006433) BioGPS data or information resource, database An extensible and customizable gene annotation portal that emphasizes community extensibility and user customizability. It is a complete resource for learning about gene and protein function. Community extensibility reflects a belief that any BioGPS user should be able to add new content to BioGPS using the simple plugin interface, completely independently of the core developer team. User customizability recognizes that not all users are interested in the same set of gene annotation data, so the gene report layouts enable each user to define the information that is most relevant to them. Currently, BioGPS supports eight species: Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Fruitfly (Drosophila melanogaster), Nematode (Caenorhabditis elegans), Zebrafish (Danio rerio), Thale-cress (Arabidopsis thaliana), Frog (Xenopus tropicalis), and Pig (Sus scrofa). BioGPS presents data in an ortholog-centric format, which allows users to display mouse plugins next to human ones. Our data for defining orthologs comes from NCBI's HomoloGene database. gene, ortholog, plug-in, report, literature, genetics, expression, reagent, protein, pathway, snp, genomics, gene annotation, function, FASEB list is listed by: Biositemaps
is related to: bioDBcore
is related to: aGEM
has parent organization: Scripps Research Institute
Novartis Research Foundation ;
NIGMS R01GM083924
PMID:19919682 Free, The community can contribute to this resource r3d100012402, nif-0000-10168 http://biogps.gnf.org/, https://doi.org/10.17616/R33J20 SCR_006433 2026-09-19 12:56:58 814
waviCGH
 
Resource Report
Resource Website
1+ mentions
waviCGH (RRID:SCR_006662) waviCGH analysis service resource, data analysis service, production service resource, service resource A versatile web-server application for the analysis and visualization of array-CGH data. genomic, copy number alteration, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20507915 Acknowledgement requested OMICS_00739, biotools:wavicgh https://bio.tools/wavicgh SCR_006662 2026-09-19 12:56:59 4
CRCView
 
Resource Report
Resource Website
CRCView (RRID:SCR_007092) CRCView analysis service resource, data analysis service, production service resource, service resource Web-based microarray data analysis and visualization system powered by CRC, or Chinese Restaurant cluster, a Dirichlet process model-based clustering algorithm recently developed by Dr. Steve Qin. It also incorporates several gene expression analysis programs from Bioconductor, including GOStats, genefilter, and Heatplus. CRCView also installs from the Bioconductor system 78 annotation libraries of microarray chips for human (31), mouse (24), rat (14), zebrafish (1), chicken (1), Drosophila (3), Arabidopsis (2), Caenorhabditis elegans (1), and Xenopus Laevis (1). CRCView allows flexible input data format, automated model-based CRC clustering analysis, rich graphical illustration, and integrated Gene Ontology (GO)-based gene enrichment for efficient annotation and interpretation of clustering results. CRC has the following features comparing to other clustering tools: 1) able to infer number of clusters, 2) able to cluster genes displaying time-shifted and/or inverted correlations, 3) able to tolerate missing genotype data and 4) provide confidence measure for clusters generated. You need to register for an account in the system to store your data and analyses. The data and results can be visited again anytime you log in. microarray, gene expression, cluster, gene, expression profile, data repository, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Bioconductor
is related to: Gene Ontology
has parent organization: University of Michigan; Ann Arbor; USA
University of Michigan; Michigan; USA ;
Institutional Fund ;
NIH U013422;
NIAID 1R21AI057875-01
PMID:17485426 Registration required biotools:crcview, nlx_99864 https://bio.tools/crcview http://helab.bioinformatics.med.umich.edu/crcview/ SCR_007092 Chinese Restaurant ClusterView 2026-09-19 12:57:01 0
Mouse Brain Atlases
 
Resource Report
Resource Website
1+ mentions
Mouse Brain Atlases (RRID:SCR_007127) Mouse Brain Atlases atlas, data or information resource High-resolution electronic atlases for mouse strains c57bl/6j, a/j, and dba/2j in either coronal or horizontal section. About this Atlas: The anterior-posterior coordinates are taken from an excellent print atlas of a C57BL/6J brain by K. Franklin and G. Paxinos (The Mouse Brain in Stereotaxic Coordinates, Academic Press, San Diego, 1997, ISBN Number 0-12-26607-6; Library of Congress: QL937.F72). The abbreviations we have used to label the sections conform to those in the Franklin-Paxinos atlas. A C57BL/6J mouse brain may contain as many as 75 million neurons, 23 million glial cells, 7 million endothelial cells associated with blood vessels, and 3 to 4 million miscellaneous pial, ependymal, and choroid plexus cells (see data analysis in Williams, 2000). We have not yet counted total cell number in DBA/2J mice, but the counts are probably appreciably lower.The brain and sections were all processed as described in our methods section. The enlarged images have a pixel count of 1865 x 1400 and the resolution is 4.5 microns/pixel for the processed sections.Plans: In the next several years we hope to add several additional atlases of the same sort for other strains of mice. A horizontal C57BL/6J atlas and a DBA/2J coronal atlas were completed by Tony Capra, summer 2000, and additional atlases may be made over the next several years. As describe in the MBL Procedures Section is not hard to make your own strain-specific atlas from the high resolution images in the MBL. genetics, anatomy, coronal, cerebellum, c57bl/6j, dba/2j, a/j, horizontal, morphology, subcortical, volume has parent organization: Mouse Brain Library Human Brain Project ;
NIDA ;
NSF ;
NIMH P20-MH 62009
nif-0000-00044 SCR_007127 2026-09-19 12:57:02 7
Mouse Transcriptome Project
 
Resource Report
Resource Website
1+ mentions
Mouse Transcriptome Project (RRID:SCR_007311) Mouse Transcriptome Project data or information resource, database Focus is the generation of a reference expression database for the C57BL/6J mouse. The current dataset will consist of 90 samples, primarily from adult tissue, and was analyzed using a technique known as Massively Parallel Signature Sequencing (MPSS). The data are stored in the Gene Expression Omnibus (GEO).The focus of this project is the generation of a reference RNA transcriptome expression database for the C57BL/6J mouse. The current dataset will consist of 90 samples, primarily from adult tissue, and was analyzed using a technique known as Massively Parallel Signature Sequencing (MPSS) NIH Blueprint for Neuroscience Research nif-0000-00176 SCR_007311 NIH Mouse Transcriptome Project 2026-09-19 12:57:03 1
Public Expression Profiling Resource
 
Resource Report
Resource Website
10+ mentions
Public Expression Profiling Resource (RRID:SCR_007274) PEPR data or information resource, database An experiment in web-database access to large multi-dimensional data sets using a standardized experimental platform to determine if the larger scientific community can be given simple, intuitive, and user-friendly web-based access to large microarray data sets. All data in PEPR is also available via NCBI GEO. The structure and goals of PEPR differ from other mRNA expression profiling databases in a number of important ways. * The experimental platform in PEPR is standardized, and is an Affymetrix - only database. All microarrays available in the PEPR web database should ascribe to quality control and standard operating procedures. A recent publication has described the QC/SOP criteria utilized in PEPR profiles ( The Tumor Analysis Best Practices Working Group 2004 ). * PEPR permits gene-based queries of large Affymetrix array data sets without any specialized software. For example, a number of large time series projects are available within PEPR, containing 40-60 microarrays, yet these can be simply queried via a dynamic web interface with no prior knowledge of microarray data analysis. * Projects in PEPR originate from scientists world-wide, but all data has been generated by the Research Center for Genetic Medicine, Children''''s National Medical Center, Washington DC. Future developments of PEPR will allow remote entry of Affymetrix data ascribing to the same QC/SOP protocols. They have previously described an initial implementation of PEPR, and a dynamic web-queried time series graphical interface ( Chen et al. 2004 ). A publication showing the utility of PEPR for pharmacodynamic data has recently been published ( Almon et al. 2003 ). microarray, expression profiling, affymetrix, metadata standard, gene, time series, data sharing, visualization, data mining, platform, blood, cell, cancer, bone, brain, eye, gut, heart, kidney, liver, lung, muscle, spinal cord, spleen, analysis is listed by: OMICtools
is related to: Gene Expression Omnibus
NINDS ;
United States Department of Defense ;
NHGRI ;
NHLBI
PMID:14681485
PMID:14596642
Public, Account required, (to download, For the analysis and visualization tools), The community can contribute to this resource nif-0000-00014, OMICS_00776 SCR_007274 2026-09-19 12:57:03 16

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