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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://health.ucdavis.edu/cancer/research/sharedresources/cmp.html
Provides services to support the development and implementation of clinical trials at UC Davis Comprehensive Cancer Center. Oversees high quality collection, processing, and analysis of clinical specimens,typically but not exclusively blood specimens, for pharmacokinetic and pharmacodynamics studies. Conducts preclinical modeling of novel anti cancer agents to test hypotheses and develop scientific rationale required for translation of laboratory concepts into clinical trials, including assessment of DM/PK/PD properties.
Proper citation: University of California Davis Health Molecular Pharmacology Shared Resource Core Facility (RRID:SCR_023588) Copy
https://www.research.colostate.edu/epf/
Core provides pathologic services ranging from animal model troubleshooting, and tissue fixation to stain slide prep and immunohistochemistry. Offers expertise in slide interpretations and quantitative histopathology in anatomic and clinical pathology. Offers molecular pathology services via Nanostring nCounter equipment.
Proper citation: Colorado State University Experimental Pathology Core Facility (RRID:SCR_023562) Copy
https://www.feinberg.northwestern.edu/sites/transplant/research/research-cores/immune-core.html
Core of Comprehensive Transplant Center provides translational mechanistic studies in human solid organ and cellular transplantations. Provides assistance with human immune monitoring needs for translational and clinical transplantation research projects.Offers immune monitoring services for translational mechanistic studies.
Proper citation: Northwestern University Immune Monitoring Core Facility (RRID:SCR_023561) Copy
https://ibt.tamu.edu/centers/translational-cancer-research/stephan-lab/mlots/index.html
Supports lead optimization programs and has established roster of medium throughput microphysiologic screening platforms including tissue- and tumor-on-a-chip platforms, organoid, and spheroid culture systems that will be used to evaluate efficacy and toxicity of new lead compounds and drug combinations.Provides resources to identify toxic liabilities in lead series molecules before entering pre-clinical or clinical testing. MLOTS can evaluate NME for cardiovascular, neuro, or liver toxicity relative to reference standards using in vitro screening platforms. Facility will potentially enhance the effectiveness of CPRITs drug discovery programs.
Proper citation: Texas A and M University Health Institute of Biosciences and Technology Microphysiological Lead Optimization and Toxicity Screening Core Facility (RRID:SCR_023717) Copy
https://med.stanford.edu/cancer/research/shared-resources/biostatistics_research_informatics.html
Core provides statistical support to SCI members by engages them on their data related needs. Specifically, BSR members assist researchers at each stage of study’s lifecycle, including project design, mid study evaluation and interpretation and reporting of results. In addition, BSR members mentor SCI investigators in research methods. BSR assists with development and review of proposed studies and planning of research related data management systems.
Proper citation: Stanford University School of Medicine Cancer Institute Biostatistics Shared Resource Core Facility (RRID:SCR_023696) Copy
https://med.stanford.edu/spectrum/ctsa-cores-and-programs/research-methods-core/berd.html
Core provides CTR investigators with support for study design development, data curation and management, and analytic strategies. Provides infrastructure through Data Studio; Clinical Office Hours; Data Science Navigation.
Proper citation: Stanford Spectrum Biostatistics Epidemiology and Research Design Core Facility (RRID:SCR_023695) Copy
http://researchservices.pitt.edu/facilities/machine-shop
Core specializes in mechanical design, fabrication, and repair of research equipment and instrumentation.
Proper citation: University of Pittsburgh Dietrich School Machine Shop Core Facility (RRID:SCR_023720) Copy
https://www.uniklinik-freiburg.de/medizin1/forschung/lighthouse-core-facility.html
Core specializes in areas of flow cytometry and cell sorting; light microscopy including confocal, widefield fluorescence, high content screening, lightsheet, slide scanning, highly multiplexed microscopy; and digital PCR / QPCR. It is located at University of Freiburg Medical Center and hosts institutions including Dept. of Medicine I, Center for Chronic Immunodeficiency (CCI), CCCF / DKTK, and Medical Faculty of University of Freiburg.
Proper citation: University of Freiburg Medical Center Lighthouse Core Facility (RRID:SCR_023785) Copy
https://www.cores.emory.edu/fcc/
Core provides sorting, sample analysis and analyzer training.Provides quantitative flow cytometric analyses on samples including blood, bone marrow, spleen, serum, plasma, solid tissues, cell extracts to support both clinical and basic research efforts. These analyses will provide insight on cell function and precursors whose abundance can be monitored as biomarkers to predict and follow progression of a wide range of diseases, such as H1N1, yellow fever, dengue, neurodegenerative diseases, stem cell studies.Provides consultations, expert training, and support for all systems and provides access to equipment.
Proper citation: Emory University School of Medicine Flow Cytometry Core Facility (RRID:SCR_023536) Copy
https://www.cores.emory.edu/tmf/index.html
Provides equipment and expertise for generating and characterizing genetically altered mouse models. Please contact us so that we can discuss your experimental needs.
Proper citation: Emory University Mouse Transgenic and Gene Targeting Core Facility (RRID:SCR_023535) Copy
https://www.cores.emory.edu/ici/index.html
Provides light microscopy. Offers expertise in imaging for experimental needs.
Proper citation: Emory University Emory Integrated Cellular Imaging Core Facility (RRID:SCR_023534) Copy
https://winshipcancer.emory.edu/research/shared-resources/emory-cellular-immunotherapy-core.html
Clinical cell manufacturing facility that prepares cell and immunotherapy products under current Good Manufacturing Practices for development of investigational new drugs and diagnostics methods.Provides GMP compliant cell manufacturing and/or consultation for translational of Emory based or external research collaborations into early phase clinical trials.
Proper citation: Emory University Emory Cellular and Immunotherapy Core Facility (RRID:SCR_023533) Copy
Provides comprehensive solution characterization of macromolecules or macromolecular interactions and assemblies. This includes description of stoichiometry, size composition, cargo loading.Core is equipped with analytical ultracentrifuges featuring multi-wavelength UV-visible detection, as well as Rayleigh interference optics and fluorescence emission detection for fluorescent tags with 488 nm excitation.
Proper citation: University of Lethbridge Canadian Center for Hydrodynamics Core Facility (RRID:SCR_023791) Copy
https://med.miami.edu/research/cores/biomarker-and-immunoassay-laboratory
Provides biomarker testing for human clinilcal research studies across multiple disciplines.Provides expertise with chemistry, special chemistry, radioimmunoassay, nephelometric and ELISA and multiplexing assay methods utilizing automated and manual procedures. Laboratory has Clinical Laboratory Improvement Act certification and follows guidelines established by CLIA for quality control and proficiency testing to ensure results. Core coordinates proper pre-analytical sample collection and processing procedures with project leaders; performs biochemical assays on samples submitted to the laboratory by investigators in manner that assures strict quality control both within and between assay runs; reports results to project staff in timely fashion; makes available expertise and technical assistance for establishing and validating new methodologies to support University of Miami investigators.
Proper citation: University of Miami Miller School of Medicine Biomarkers and Immunoassay Laboratory Core Facility (RRID:SCR_023705) Copy
https://moffitt.org/research-science/shared-resources/molecular-genomics/
Molecular Genomics Core Facility at Moffitt Cancer Center in Tampa, FL offers services to assess gene expression, epigenetic modification and sequence variation. Performs bulk and single cell RNA and DNA sequencing on Illumina platform, NanoString nCounter, GeneChip and Illumina array services.Offers services to discuss your project and timeline for your project.
Proper citation: Moffitt Cancer Center Molecular Genomics Core Facility (RRID:SCR_012333) Copy
https://www.cores.emory.edu/rbc/
One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.
Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy
https://cbc.arizona.edu/research/support-services/facilities/nuclear-magnetic-resonance-nmr
Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.
Proper citation: University of Arizona Nuclear Magnetic Resonance Core Facility (RRID:SCR_012716) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html
MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.
Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy
https://www.sbpdiscovery.org/biomedical-research/shared-resources/cancer-metabolism
Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) Copy
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
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