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http://it.med.harvard.edu/ris

Core facility that positions digital imaging resources right where the research is being done: in Harvard Medical School''s quad-based basic science departments. The convenience of these locations makes it easy for researchers to access digital imaging expertise when faced with research imaging questions. This accessibility and convenience is supplemented by substantial web-based assistance, making Research Imaging Solutions a 24/7 resource. Seminars, Workshops and printed training materials guide faculty, students, post-docs and lab personnel on supported imaging hardware and software products. Supported hardware and software packages includes: Adobe products including Acrobat, Photoshop, and Illustrator; ACD Canvas; Microsoft Office applications including Word, PowerPoint and Excel; film recorders, slide and flatbed scanners, and color output devices such as color laser printers, poster printers and photo quality printers.

Proper citation: HMS Research Imaging Solutions (RRID:SCR_012302) Copy   

•   Source: SciCrunch Registry

http://www.neurodiscovery.harvard.edu/research/neurobehavior_laboratory.html

Core facility that provides the following services: Surgery/necropsy service. Mouse models have become a popular and successful approach to elucidating the physiological and pathological roles of individual genes and are truly crucial to accelerate the development of effective treatments and cures for Alzheimer''''s, Parkinson''''s, ALS, MS and other neurodegenerative diseases. The increasing demand for mouse behavioral studies within the neuroscience community has led the Harvard NeuroDiscovery Center to develop a major new, state of the art mouse behavior laboratory, located in the Longwood medical area and carefully designed to meet the exacting standards required for this type of work. The NeuroBehavior Laboratory (NBL) will provide the Harvard community and other investigators access to a broad range of reliable behavioral/cognitive tests necessary to analyze and interpret the impact of a genetic, surgical or pharmacologic manipulation on specific behaviors. They can provide: * Assistance with experimental design. * Support for grant applications that have a significant component of mouse neurobehavioral research. * Full, fee-for-service, mouse behavioral testing services. * Training in all aspects of mouse neurobehavioral testing. * Assistance with data analysis and interpretation.

Proper citation: HNDC NeuroBehavior Laboratory Core (RRID:SCR_012396) Copy   

•   Source: SciCrunch Registry

http://microscopy.dfci.harvard.edu

Core facility that provides state-of-the-art imaging microscopy technology for fixed and live cells, tissues and multi-photon animal imaging along with scientific and technical expertise to assist in experimental design and optimal image collection. Imaging techniques available include Standard fluorescence, Live-cell long term imaging, Confocal, Deconvolution, Fluorescence spectral detection, TIRF, FRET, Calcium imaging, Multi-photon, and Fluorescence lifetime imaging. Available equipment includes: Yokogawa spinning disk confocal microscope (Andor), Leica SP5 laser scanning confocal with a white light laser, Zeiss 710 confocal/multi-photon, Nikon inverted widefield fluorescence microscope. Other services include training on all equipment, consultation about various imaging techniques and assistance with image analysis. In addition, staff are available to assist with troubleshooting regarding microscopes in individual research labs. All services are available on a fee basis, and equipment is available for either assisted use or unassisted use after training by core staff. NEW: The core has established a collaboration with Rockland Immunochemicals to provide free, trial-size samples of primary and secondary antibodies that may be useful in your experiments.

Proper citation: DFCI Confocal and Light Microscopy Core Facility (RRID:SCR_012314) Copy   

•   Source: SciCrunch Registry

http://cccb.dfci.harvard.edu

Core facility that provides the following services: Microarray and other genomic data analysis, MiSeq. The Center provides broad-based support for the generation, analysis, and interpretation of genomic and other large-scale data in the context of basic, clinical and translational research. The CCCB has three primary elements. * The CCCB sequencing facility offers a wide range of services to assist in the design and execution of next-generation sequencing projects. Utilizing the Illumina (Solexa) sequencing technology, they currently support a number of applications inlcuding ChIP-Seq, RNA-Seq, whole genome, whole exome, and targeted re-sequencing. * The analytical services and support platform aims to provide state-of-the-art assistance in the collection, management, analysis, and interpretation of large-scale data with a focus on data generated using ''''omic technologies. In addition, they offer software, services, and training designed to assist investigators in advancing their research. * The CCCB research program is focused on development of new methods for improving analysis and interpretation of genomic data through integration of diverse data types with the goal of creating open-source software tools to be made freely-available to the research community.

Proper citation: DFCI Center for Cancer Computational Biology (RRID:SCR_012688) Copy   

•   Source: SciCrunch Registry

http://www.neurodiscovery.harvard.edu/research/lddn_2.html

Core facility that provides the following services: Assay design and development service. The NeuroDiscovery Center''''s Laboratory for Drug Discovery in Neurodegeneration (LDDN) was established to discover chemical agents from which we and others will develop a new generation of drugs to treat neurodegenerative diseases (including degenerative diseases of the eye and ear). To accomplish this goal, LDDN has recruited a permanent staff of industry-seasoned scientists with expertise in assay development, laboratory automation, informatics, and medicinal chemistry, to work in close collaboration with principal investigators from the academic neuroscience community. In this way, LDDN helps transform discoveries in the basic biology of neurodegeneration into opportunities for drug discovery. (While priority is given to members investigating neurodegenerative diseases and the central nervous system, we welcome inquiries from all investigators.)

Proper citation: HNDC Drug Discovery in Neurodegeneration (RRID:SCR_012680) Copy   

•   Source: SciCrunch Registry

http://www.ohsu.edu/xd/research/centers-institutes/onprc/research-services/research-support/virology.cfm

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 5, 2022. Core facility that provides the following services: DNA isolation service, RNA isolation service, Cloning and endotoxin-free plasmid preparation service, Virus plaque assay, SIV p27 protein ELISA, HIV p24 protein ELISA with sample prep, Real time PCR titer of lentivirus prep with sample prep, Coculture of animal tissues/fluids service, Virus plaque purification service, Virus growth curve service, Protein determination, Bradford method, Crude viral DNA prep service, Gradient purified viral DNA prep service, Southern blot for viral DNA, Viral Real-time PCR, RhCMV Real-time PCR, HSV 1/2 B virus antibody ELISA, single dilution service, RhRRV antibody ELISA, single dilution, RhSFV antibody ELISA, single dilution, SIV antibody ELISA, single dilution, Virus antibody ELISA, RhCMV antibody ELISA, Virus neutralization service, Polyclonal IgG preparation, SIV in vitro susceptibility, p27 ELISA, Vaccinia (MVA) virus plaque assays, Antiviral antibody determination by ELISA, SIV in vitro infectivity (leukocytes) service, Viral load quantification with qPCR, Virus detection using nested PCR, Virus stock production, Cytomegalovirus plaque assays and purification, Cytomegalovirus stock and vector production, Western blot service for viral protein, Cell sample processing and banking, Nucleic acid isolation and purification service, Virus cloning and plasmid preparation service, Vaccinia (MVA) virus stock and vector production. The Core''''s overall goal is to advance the efforts of the Oregon National Primate Research Center (ONPRC), the Vaccine and Gene Therapy Institute (VGTI), and collaborative research programs focused on nonhuman primate (NHP) infectious disease models and those using viral vectors as tools to modify genes or deliver macromolecules through provision of expertise, reagents, standardized assays, and training in the use of infectious viral agents in their research programs. The MVSC provides specialized expertise and infrastructure in five essential areas: * Virus identification and quantification in clinical specimens * Production of virus stocks, virus vectors, and viral antigen preparations * Serologic assays to assess host antiviral immune responses * Maintenance of cell stocks and sample processing * Development of new reagents and standardized assays The MVSC has considerable experience and expertise in both viral diagnostics and production, particularly for AIDS and CMV pathogenesis and vaccine studies, and in adenoviral vector production.

Proper citation: OHSU Molecular Virology Support Core (RRID:SCR_012730) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-e17f-6dab-2162-17a280000000

Core facility that provides the following services: Sample processing/storage. The Harvard NeuroDiscovery Center Biomarker Study aims to discover and validate biomarkers for neurodegenerative diseases.

Proper citation: Harvard NeuroDiscovery Center - Biomarker Study (RRID:SCR_000881) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-eda0-e0bc-6bbe-6fcf80000000

The most comprehensive health sciences collection in Puerto Rico.

Proper citation: UPR Conrado F. Asenjo Library (RRID:SCR_002405) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250c-1333-43fb-601a80000000

Core facility that provides the following services: Classic confocal imaging experiments.

Proper citation: UPR Confocal Microscope Facility (RRID:SCR_002408) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-3632-9a76-dacb-da6080000000

Core facility that provides the following services: FACS AriaCell Sorting, LSRII-Analytical Cytometry, AutoMacs-Magnetic Sorting, EasyCyte-Cell Counting/Viability. We enjoy state-of-the-art digital instrumentation maintained at the highest standards we can attain. This quality control allows researchers to sort cells at high efficiency and purity under the proper conditions or to run analytical experiments with as many as 17 different fluorochromes simultaneously. We are dedicated to providing the best service and training possible to ensure the best results attainable for our research scientists and physicians. Please investigate the pages of this website to address your scheduling needs and questions relating to flow cytometry research, methods and fees

Proper citation: Vanderbilt Flow Cytometry Core Laboratory (RRID:SCR_000895) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/community/profile/id/2228

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 13,2025.Core facility that provides access to isolated pancreatic islets from normal and diabetic models and performs islet functional analysis. The IPA Core also provides solutions for high-resolution whole slide imaging and access to image analysis tools for quantitative assessment of pancreatic islet morphology.

Proper citation: Vanderbilt Diabetes Research and Training Center Islet Procurement and Analysis Core (RRID:SCR_000896) Copy   

•   Source: SciCrunch Registry

http://utsa.eagle-i.net/i/00000135-595e-a213-d7c8-cf3780000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 13,2025. Core facility located at the University of Texas at San Antonio.

Proper citation: UTSA Engineering Core (RRID:SCR_000894) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013a-64b9-8347-01af-beb880000000

Core facility that provides the following services: Biomarker quantification by mass spectrometry. This core provides sophisticated analytical services based on liquid chromatography-mass spectrometry.

Proper citation: Penn Translational Biomarker Core (RRID:SCR_000891) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/mouse.html

Core which provides researchers with resources for performing metabolic studies in mice. It also provides services, innovative techniques, and helpful consultation to both experienced and novice investigators with regards to metabolic questions.

Proper citation: Penn Diabetes Research Center Mouse Phenotyping Physiology and Metabolism Core (RRID:SCR_000888) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/bauer-core-laboratory-fas-harvard

Core facility that provides the following services: Liquid handling, Long read sequencing, Cell sorting service, Cell analysis service, Imaging systems service, Microarrays service, Sequencing service, Genotyping service, Fragment analysis, Solexa DNA sequencing service, Solexa gene expression service, Solexa small RNA service, Solexa ChIP-Seq service, Real-time quantitative PCR service, Protein-molecule interaction service, Library replication service, Nucleic acid isolation service, Nucleic acid shearing service, DNA, RNA and protein sample analysis service. Their goal is to advance research efforts in the life sciences that cannot readily be accomplished in the traditional academic laboratory because of a need for expensive instrumentation or automation, scientific or organizational infrastructure, or multidisciplinary expertise. To promote cutting-edge research and to foster scientific collaborations, we make our extensive laboratory and computational resources available to scientists at Harvard. Our technical staff provide expertise and hands-on training in protocols and the use of instrumentation for a nominal fee. Researchers can sign up to use the instrumentation through an on-line scheduling system and conduct their experiments independently.

Proper citation: Harvard FAS Bauer Core Laboratory (RRID:SCR_001031) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000013f-dd9e-c2d6-8fa3-ce9080000000

The SYNERGY Clinical Research Unit (CRU) is an outpatient research support unit that offers investigators a full array of services for the conduct of clinical research. The CRU is available to any Dartmouth faculty or researcher wishing to access dedicated space and staff resources for the efficient conduct of clinical research.

Proper citation: Dartmouth SYNERGY Clinical Research Unit (RRID:SCR_005645) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012b-3a20-eab4-bd3e-55f580000000

Core facility that provides the following services: Printed circuit fabrication, Printed circuit board assembly, System design and fabrication.

David Collins is NASA certified for electrical assembly.

Proper citation: Dartmouth Science Division Electronics Shop (RRID:SCR_003589) Copy   

•   Source: SciCrunch Registry

http://www.brighamandwomens.org/Departments_and_Services/radiology/Research/BRIC/default.aspx

Imaging Core facility that provides a comprehensive research imaging service to meet the needs of investigators and research subjects using imaging facilities at Brigham and Women's Hospital (BWH). A unique feature of BRIC is the complete anonymity of research subjects. Research image scheduling, image acquisition and image storage are all kept completely separate from BWH clinical Radiology systems. The BRIC provides the administrative infrastructure, customer service architecture and institutional support to promote investigative applications of imaging technologies.

Proper citation: BWH Research Imaging Core (RRID:SCR_002708) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-e19f-9e69-d807-77a880000000

The molecular lab at Weld Hill is well equipped for modern molecular studies, from RNA expression studies to phylogenetic analyses.

Proper citation: Arnold Arboretum of Harvard University: Weld Hill Molecular Lab (RRID:SCR_004781) Copy   

•   Source: SciCrunch Registry

http://hunter-cuny.eagle-i.net/i/00000136-7eb5-5555-949b-425080000000

Core facility that provides the following services: Training Service, TEM Analysis Service. ?The Nanoscale Analytical Facility is equipped with Jeol 2100 EDAX operated at 200kV. Nanomaterial containing samples of inorganic as well as organic building blocks, macromolecular constructs, metallic nanoparticles, metal oxide nano-powders are often imaged.

Proper citation: Hunter Nanoscale Analytical Facility (RRID:SCR_005617) Copy   

•   Source: SciCrunch Registry