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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.albany.edu/genomics/microarray-ngs.html
Provides services for DNA microarrays for large scale analysis of gene expression,gene regulation, exon splicing, epigenetics. Provides instrumentation for scanning of protein arrays.Offers services in RNA sequencing, ChIP-seq, ChIRP-seq, metagenomics and miRNA sequencing.Provides bioinformatics tools for analysis of results of microarray and sequencing experiments. Houses Illumina Nextseq500 and Ion PGM platforms for next generation sequencing. Provides instruments for Next gen sequencing including Illumina, MinIon, Wafergen-Takara, 10x genomics and for DNA microarrays including Affymetrix, Agilent.
Proper citation: University at Albany SUNY Center for Functional Genomics Microarray and Next Gen Sequencing Core Facility (RRID:SCR_018262) Copy
http://nemoursresearch.org/cores/bcl/
Develops research projects in pediatric genetics and provides essential services in molecular biology and genetics to Nemours clinicians and research staff and to affiliates researchers of University of Delaware and Thomas Jefferson University. Resource for staff of Alfred I. duPont Hospital for Children, Nemours affiliates, COBRE / INBRE investigators and outside customers. Offers expertise in molecular genetics and genomics. Operates according to policies set forth by federal CLIA standards.Services provided include Ion Torrent PGM Next Generation Sequencing, QuantStudio (QS) 3D Digital PCR, Cell Line Authentication, Nucleic Acid Quality Number (AATI Fragment Analyzer),Genotyping including Allelic Discrimination Probes (SNP Real-Time PCR), Affymetrix Microarray (CNV CytoScan, SNP arrays), Fragment Analysis (Capillary Electrophoresis up to 1200 bp), DNA Sequencing (Sanger Sequencing), Expression Analysis including Affymetrix Microarray (global gene expression, transcriptome assays), Pathway-focused Real-Time qPCR (mRNA and miRNA). Shared Instrumentation including Beckman Biomek 3000 Liquid Handler, NanoDrop 2000c, ABI7900 384-well Real-Time Genetic Analyzer, PCR Tamer, Thermocyclers.
Proper citation: Nemours Biomolecular Core Facility (RRID:SCR_018265) Copy
Core provides services including high throughput next generation sequencing (NGS) to support whole genome, whole exome, RNA-Seq, single cell RNA-Seq, microbiome and global chromatin and methylation studies, biostatistical and bioinformatic support for NGS projects, access to DNA/RNA sequence analysis software, automated Sanger DNA sequencing, genotyping and RNA/DNA quality assessment, access to shared instrumentation such as plate readers, real time thermal cyclers, Agilent Bioanalyzers, fluorimeters, and spectrophotometers.
Proper citation: Marshall University School of Medicine Genomics Core Facility (RRID:SCR_018885) Copy
https://med.virginia.edu/gatc/
Core offers instrumentation and expertise in all areas of bulk and single cell NGS genomics and transcriptomics, as well as training to access core shared instrumentations. Services include RNA Seq, CHIP Seq, ATAC Seq, Amplicon DNA Seq, 16S ribosomal gene sequencing, shot gun sequencing for small genomes and whole exome sequencing.10X Genomics resources include single cell CNV, VDJ, and 3 or 5 RNA seq as well as linked reads.Core provides real time and droplet digital PCR services most suitable for targeted gene expression, SNP genotyping and CNV discovery.
Proper citation: Virginia University School of Medicine Genome Analysis and Technology Core Facility (RRID:SCR_018883) Copy
https://sciex.com/products/mass-spectrometers/qtof-systems/tripletof-systems/tripletof-5600-system
Mass spectrometry system that combines SCIEX Triple Quad technology with Accelerator TOF Analyzer, to deliver nominal mass and accurate mass benefits in single platform. Integrates comprehensive, qualitative exploration, rapid profiling, and high-resolution quantitation workflows.
Proper citation: SCIEX: TripleTOF 5600+ Mass Spectrometer System (RRID:SCR_018053) Copy
Real-time PCR system that performs high performance, multicolor real-time PCR. Has five color platform that is calibrated for broadest range of dyes available: FAM, SYBR Green I, VIC, JOE, NED, TAMRA, Cy3, ROX, Texas Red, and Cy5 dyes. Thermal cycling block is built to reduce environmental exposure and contamination risk.
Proper citation: Thermo Fisher: Applied Biosystems: 7500 Real-Time PCR System (RRID:SCR_018051) Copy
Benchtop flow cytometer features reliable performance and accurate results for experiments requiring up to 10 parameters. Fixed alignment flow cell minimizes startup time and improves reproducibility. Patented optical design maximizes signal detection and increases sensitivity and resolution for each color in multicolor assay.
Proper citation: BD Biosciences: Canto II Flow Cytometer (RRID:SCR_018056) Copy
https://www.thermofisher.com/order/catalog/product/4351405#/4351408
Real Time quantitative PCR system that combines 96- and 384-well plate compatibility and the TaqMan Low Density Array with fully automated robotic loading and now also offers optional Fast real-time PCR capability. High-throughput Real-Time PCR system that detects and quantitates nucleic acid sequences. Uses fluorescent-based PCR chemistries to provide: Quantitative detection of nucleic acid sequences using real-time analysis and Qualitative detection of nucleic acid sequences using end-point and dissociation-curve analysis.
Proper citation: Thermo Fisher: Applied Biosystems: 7900HT Fast Real-Time PCR System (RRID:SCR_018060) Copy
Multimode microplate reader that provides speed, ultra-high throughput, and maximum sensitivity across all detection technologies. Provides higher sensitivity for time-resolved fluorescence TRF applications, and Enhanced Security software option includes tools to facilitate 21 CFR Part 11 compliance for integration into regulated environments GxP.
Proper citation: Perkin Elmer: EnVision 2105 Multimode Plate Reader (RRID:SCR_018038) Copy
http://www.syntechinnovation.com/images/catalog/advance-analytical/8chromatography/HPLC_Brochure.pdf
Liquid chromatography analyzer that achieves high levels of sample throughput by use of either binary or quaternary pumps and interchangeable autosamplers. High pressure operation and use of short columns with small diameter media result in fast, high resolution separations. Features includedu al-lamp design and temperature control of diode array detectors.
Proper citation: Agilent: 1200 High Performance Liquid Chromatography System (RRID:SCR_018037) Copy
https://www.tekyard.com/Item/inventoryId/209687
Molecular imager system for performing gel and blot analysis. This system provides both PhosphorImager capabilities along with non-radioactive fluorescent labeling techniques-direct fluorescence and chemifluorescence. It can be used for non-radioactive gel and blot analysis methods or radioisotope techniques. Storm 840 scans storage phosphor screens plus fluorescent gels and chemifluorescent blots in the 35 x 43 cm scanning area.
Proper citation: Molecular Devices: Molecular Dynamics Storm 840 Molecular Imager (RRID:SCR_018031) Copy
http://apexx-equipment.com/veterinary-mfg/agfa/agfa-cp1000-automatic-film-processor-1
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 10,2024. Automatic film processor for low-volume processing or back-up purposes. Its features include fast start up (7 minutes from cold start) and 125-second cycle time. Uses simple, accessible film transport system with fewer rollers than conventional heavy roller racks, infrared dryer instead of hot-air dryer, 400 watts of power when in operation and 100 watts in standby mode, and automatic temperature control and drying.
Proper citation: AGFA: CP1000 Automatic Film Processor (RRID:SCR_018030) Copy
https://www.thermofisher.com/order/catalog/product/00-0079#/00-0079
Microarray processor that washes and stains GeneChip arrays.110V and 220V compatible.
Proper citation: Thermo Fisher: Affymetrix: GeneChip 450 Fluidics Station Microarray Processer (RRID:SCR_018034) Copy
Microarray scanner that performs genetic and compound analysis. Coupled with GenePix ProMicroarray Image Analysis Software and Acuity Microarray Informatics Software for acquisition and analysis of data from all types of arrays, including nucleic acids, proteins, tissues, and cells. Scanner flexibility allows to configure scanning and analysis of one slide or many, whether they are all alike or each is different. Slide loader accommodates low- and high-density, opaque, mirrored, or translucent, plastic or glass, commercial or homebrew slides.
Proper citation: Molecular Devices: GenePix 4000B Microarray Scanner (RRID:SCR_018049) Copy
https://www.thermofisher.com/order/catalog/product/ND-2000
Full-spectrum, UV-Vis spectrophotometer used to quantify and assess purity of DNA, RNA, Protein and more. The NanoDrop 2000 is microvolume spectrophotometer with patented sample retention technology that measure sample volumes as small as 0.5L.
Proper citation: Thermo Fisher: NanoDrop 2000 Spectrophotometer (RRID:SCR_018042) Copy
Personal sized 96-well thermal cycler that performs both basic PCR and cycle-sequencing applications using 0.2 mL reaction tubes or 96-well reaction plates. Its dimensions are 21 cm (8.3 in.) wide and 36 cm (14.2 in.) deep with cooling vents.
Proper citation: Thermo Fisher: Applied Biosystems: 2720 Thermal Cycler (RRID:SCR_018045) Copy
https://www.labx.com/product/roche-454-gs-flx
Genetic sequencer that sequences clinically relevant exons and identifies genomic variations in solid tumors treated with antibody-based medicine. Scaled version of Genome Sequencer FLX System for use by individual labs. Features include simple sample preparation workflow, overnight sequencing and data processing, and suite of data analysis software.
Proper citation: Roche: 454 GS FLX Genome Sequencer (RRID:SCR_018028) Copy
https://www.bio-rad.com/en-us/product/bio-plex-200-systems?ID=715b85f1-6a4e-41b3-b5d9-80202d779e13
Suspension array system which offers protein and nucleic acid researchers multiplex assay solution permiting analysis of up to 100 biomolecules in single sample.
Proper citation: Bio-Rad: Bio-Plex 200 System (RRID:SCR_018026) Copy
https://pedsresearch.org/uploads/pages/img/LuminexManual_LX100.pdf
Flow cytometry analyzer system for individual labs that performs up to 100 different tests in single reaction volume and can use either magnetic beads or plain polystyrene beads.
Proper citation: Luminex: 100 Flow Cytometry Analyzer System (RRID:SCR_018025) Copy
https://www.sonybiotechnology.com/us/instruments/sp6800/
Analyzer that uses spectral technology to collect photons from 420nm to 800nm. Global standardization mode automatically sets system to master specification with single click. Sony patented Flowpoint core stability and tracking system and automated QC ensure highest resolution possible of target populations.
Proper citation: Sony biotechnology: SP6800 Spectral Cell Analyzer (RRID:SCR_018067) Copy
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