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Conducts comprehensive analysis of cellular lipids that encompass fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, and prenol lipids.
Proper citation: Wayne State University School of Medicine Lipidomics Core Facility (RRID:SCR_022682) Copy
http://cils.northeastern.edu/facilities
Located in ISEC research center and includes advanced imaging instruments. CILS has three core facilities: Microscopy Core (confocal/multi-photon/lightsheet microscopes), Flow Cytometry Core (cell analyzer/sorter) and Preclinical Imaging Core (3T small animal MRI and ultrasound).
Proper citation: Northeastern University Institute for Chemical Imaging of Living Systems Core Facility (RRID:SCR_022681) Copy
https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/
Provides secure environment for investigators analyzing protected health information. �It coordinates acquisition, storage, and analysis of data from private and government sources (e.g., Medicare, Medicaid, and others) and facilitates their use by researchers who seek to answer important questions regarding health policy and health care.�
Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Health Services Research Data Center Core Facility (RRID:SCR_022439) Copy
https://www.vet.upenn.edu/research/core-resources-facilities/comparative-pathology-core
Provides support to investigators utilizing animal models to study disease. Comparative Pathology Core, Abramson Cancer Center shared resource, provides expert pathological characterization and validation of mouse and other animal models used in biomedical research by offering expertise of board certified veterinary pathologists and access to histology, immunohistochemistry, and digital pathology services.
Proper citation: University of Pennsylvania Penn Vet Comparative Pathology Core Facility (RRID:SCR_022438) Copy
https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/
Provides LDI affiliated investigators access to high quality, skilled data analysts. HEDAP recruits, trains, and manages group of masters level and PhD level statistical analysts. These analysts work with multi disciplinary investigators across funded projects using statistical software packages such as SAS, Stata, and R to manipulate and analyze health care data under guidance of investigators and other collaborators.
Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Data Analyst Pool Core Facility (RRID:SCR_022437) Copy
https://www.vet.upenn.edu/research/core-resources-facilities/imaging-core
Provides access to optical imaging capabilities for researchers at the University of Pennsylvania, Perelman School of Medicine, Children's Hospital of Philadelphia, and Wistar Institute. Provides instruments and expertise to perform widefield, confocal, multiphoton/intravital imaging, fluorescence lifetime imaging, high content live cell screening, long term single cell imaging, second harmonic imaging, structured illumination super resolution, and total internal reflection fluorescence microscopy, as well as software tools for image analysis. Core has adjacent (in and out) ULAR approved facility to house animals for long term live animal studies.
Proper citation: University of Pennsylvania Penn Vet Imaging Core Facility (RRID:SCR_022436) Copy
https://www.vet.upenn.edu/research/core-resources-facilities/animal-model-core-corl
Supports discovery to invention to innovation in medical translation.Provides animal model development to enhance scientific rigor during in vivo studies in experimental or naturally occurring disease models. Studies can start on small scale leading towards pivotal non-clinical IND/IDE-enabling trials in support of FDA or OUS-FDA submissions. Core hosts PIs, trainees and sponsors during clinical procedures to support and enrich their experience in cross functional team setting.
Proper citation: University of Pennsylvania Animal Model Core Facility (RRID:SCR_022435) Copy
https://www.cardiff.ac.uk/biosciences/research/technology-research-hubs/bioimaging-unit
Provides advanced light microscopy imaging modalities and histological services. Offers training and application support in experimental design, sample preparation, data generation and analysis through to scientific publication and grant assistance.
Proper citation: Cardiff University Bioimaging Hub Core Facility (RRID:SCR_022556) Copy
https://med-upenn.corefacilities.org/service_center/5129/?tab=about
Offers Illumina sequencing and bioinformatic expertise to assist researchers�with gene therapy trial evaluations, viral integration profiling,�CRISPR off-target�analyses. Assists with bioinformatic analyses including RNAseq transcription profiling�and 16S taxonomic assignments.�
Proper citation: University of Pennsylvania Perelman School of Medicine Viral Molecular High Density Sequencing Core Facility (RRID:SCR_022433) Copy
https://www.ohsu.edu/integrated-genomics-laboratory
Lab houses three cores providing support and services from nucleic acid isolation through data generation on multiple genomic and molecular analysis platforms. Nucleic acid extraction, qPCR, and Nanostring profiling services are available through the Gene Profiling Shared Resource for gene expression profiling, microRNA profiling, DNA genotyping and copy number analysis, and DNA methylation analyses. Currently running QuantStudio real-time PCR system. Comprehensive RNA and DNA extraction and quality assessment services available. Massively parallel sequencing (NGS) services, including library preparation, are available through Massively Parallel Sequencing Shared Resource on Illumina NovaSeq 6000 and NextSeq platforms. 10x Genomics single-cell and single-nuclei analysis services available. Cell line authentication, DNA plating, and custom oligo services are available through DNA Services Core.
Proper citation: Oregon Health and Science University Integrated Genomics Laboratory Core Facility (RRID:SCR_022651) Copy
https://www.sfu.ca/fhs/research/research-centres-labs/flow-cytometry-laboratory.html
Offers high speed cell sorting and bench top flow cytometric analysis services as well as training and support to research community.Instruments include BD FACSAria Fusion Cell Sorter,4-Laser | 16-Colour (2B/3R/5YG/6V) within Class II Type A2 BioSafety Cabinet and BD LSRFortessa X-20 Cell Analyzer 4-laser | 16-Colour (2B/3R/5YG/6V).
Proper citation: Simon Fraser University Flow Cytometry Lab Core Facility (RRID:SCR_022492) Copy
https://www.cincinnatichildrens.org/research/cores/mmac
Provides solutions in areas of study design, bioinformatic processing of amplicon and shotgun metagenomic sequencing data, integration of metagenomic and clinical data structures, and statistical analyses of microbial community samples. MMAC works closely with Microbial Genomics and Metagenomics Laboratory to streamline workflows for metagenomic sequencing, bioinformatic processing, and statistical analysis of microbiome projects.
Proper citation: Cincinnati Children's Hospital Microbial Metagenomics Analysis Center Microbial Genomics and Metagenomics Core Facility (RRID:SCR_022649) Copy
Facilitates scientific research of nervous system function to enhance development and testing of novel therapeutic strategies for treatment of nervous system disorders. Provides resource capacity typically unavailable or impractical in individual laboratory. Major areas of specialization include surgical approaches to model production and assessment, behavior testing of sensorimotor functions, in vivo electrophysiological recording (EEG, EMG, ERP). Procedures are intended for mice and rats. Procedures can be developed based on client interests.
Proper citation: University of Texas Southwestern Medical Center Neuro Models Core Facility (RRID:SCR_022529) Copy
https://bauercore.fas.harvard.edu/
Helps to advance research efforts in life sciences that cannot readily be accomplished in the traditional academic laboratory because of need for expensive instrumentation or automation, scientific or organizational infrastructure, or multidisciplinary expertise. Provides expertise and hands-on training and use of instrumentation for nominal fee. Researchers can sign up to use instrumentation through on-line scheduling system and conduct their experiments independently.
Proper citation: Harvard University Bauer Core Facility (RRID:SCR_022656) Copy
https://www.cincinnatichildrens.org/research/cores/dna-sequencing-genotyping
Supports production and analysis of DNA and RNA related data. Provides DNA and RNA sequencing, Next Generation sequencing, DNA extraction and high and low throughput SNP genotyping.
Proper citation: Cincinnati Children's Hospital DNA Sequencing and Genotyping Core Facility (RRID:SCR_022630) Copy
Supports development, scale -up and processing of innovative cell based therapies for clinical studies.
Proper citation: Cincinnati Children's Hospital Cell Manipulation Laboratory Core Facility (RRID:SCR_022627) Copy
https://www.cincinnatichildrens.org/research/cores/dmac
Centralized resource for clinical research data management, programming for clinical research databases, and statistical analysis.
Proper citation: Cincinnati Children's Hospital Data Management and Analysis Center Core Facility (RRID:SCR_022625) Copy
https://www.cincinnatichildrens.org/research/cores/mouse-core
Offers services for researchers exploring cancer systems through animal models. Provides animals from specific inbred mouse strains primarily used in cancer and hematopoietic research, offers cell transplant, harvest and irradiation services and can handle animal cancer model systems involving xenotransplant procedures.
Proper citation: Cincinnati Children's Hospital Comprehensive Mouse and Cancer Core Facility (RRID:SCR_022624) Copy
Supplies mononuclear cells, stem cells or other enriched cell populations. Provides stem cells and other tissue samples from normal donor or patient populations such as disease specific repositories or specific research studies requiring sample processing. Samples are provided fresh or cryopreserved according to availability, unprocessed or with further lab processing.Common processing techniques include PBMC isolation,Serum and plasma isolation,Separation of marker specific populations,Flow cytometric characterization of samples,Interferon gamma EliSpot.Additional services may be available upon request
Proper citation: Cincinnati Children's Hospital Cell Processing Core Facility (RRID:SCR_022623) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/camri/index.html
Provides research MRI capabilities for investigators at UNMC and across greater Omaha area. Housed in Hixson-Lied Center, CAMRI operates Siemens 3T Prisma MRI instrument that can collect high quality data of any MR modality using advanced gradients and research grade pulse sequences. Variety of head coils (20-, 32-, and 64-channel) are available to optimize data collection for needs of specific studies. Studies incorporating functional MRI can take advantage of CAMRI�s suite of MRI-compatible response devices, mirrored 32-inch LCD screen, and integrated stimulus display computer.
Proper citation: University of Nebraska Medical Center Advanced Magnetic Resonance Imaging Core Facility (RRID:SCR_022468) Copy
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