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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://eagle-i.ea.vanderbilt.edu/i/00000139-10e8-f177-dacb-da6080000000
Core facility that provides the following services: Simple Protein Identification, Multidimensional Protein Identification Technology, 2D Difference Gel Electrophoresis (2D-DIGE). The Proteomics Laboratory provides state-of the-art MS instrumentation and analytical methods to analyze proteins and proteomes.
Proper citation: Vanderbilt Mass Spectrometry Research Center Proteomics Laboratory (RRID:SCR_010190) Copy
https://labnodes.vanderbilt.edu/community/profile/id/1133
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core facility that provides training and expertise in nutrition/diet methodology to obtain valid and reliable assessment and analyses of dietary intakes, nutritional status, body composition and metabolism.
Proper citation: Vanderbilt Diabetes Research and Training Center Vanderbilt Diet Body Composition and Metabolism Core Facility (RRID:SCR_010191) Copy
http://eagle-i.ea.vanderbilt.edu/i/00000139-2ffc-7399-dacb-da6080000000
The overall goal of the Histology and Morphometry Core is 1) to provide a common facility and expertise for the broad spectrum of morphologic studies that may be required for interpretation of studies of various models of kidney disease and their response to interventions; 2) to provide tissue samples from existing archival specimens from various mouse and rat kidney disease models that may be used for exploration and characterization of expression patterns of various novel target molecules; and 3) to develop and enhance existing morphologic techniques to improve the ability of center investigators to localize specific molecules and tissue sections, and to interpret their significance based on the spatial localization and relationship to patterns of injury.
Proper citation: Vanderbilt Mouse Kidney Histology and Morphometry Core (RRID:SCR_010192) Copy
http://hawaii.eagle-i.net/i/0000012b-3599-5885-2f73-b43980000000
Core facility that provides the following services: Construction and validation of random-sheared DNA fragment libraries, DNA sequencing (Sanger) service, 96-well plasmid preparation service, Genotyping/fragment analysis, BAC end sequencing, Plasmid library construction service, Genome sequencing project. The ASGPB genome infrastructure currently consists of several state-of-the-art capillary-based DNA sequencers and accessory equipment to deal with large sample volumes. The facility can process up to 9000 samples per day with a projected sequence output of 6.75 Million bases. Several prokaryotic and one eukaryotic genome project are currently in progress. The facility offers DNA sequencing services for a wide range of templates including plasmid DNA, PCR fragments, cosmid DNA, and Bacterial Artificial Chromosomes (BACs). Sequencing reactions are performed using Applied Biosystems BigDye terminator chemistry and are run on ABI 3730XL capillary-based DNA sequencers.
Proper citation: UH Manoa Sequencing Facility (RRID:SCR_010114) Copy
http://upr.eagle-i.net/i/0000012b-00bf-6765-9e37-5ded80000000
Core facility that provides the following services: Sequencing service, Genotyping service. We are a low cost, fee-for-service facility designed to provide students and researchers in Puerto Rico with access to state-of-the-art equipment for collecting sequence and genotype data. We offer full service sequencing (reaction set-up, clean up, run and delivery) and fragment analysis data generation and offer personalized support to our users.
Proper citation: UPR AABRE Program: Sequencing and Genotyping Facility (RRID:SCR_010118) Copy
http://upr.eagle-i.net/i/0000012a-f732-79cc-6bbe-6fcf80000000
THIS RESOURCE IS NO LONGER IN SERVCE, documented January 24, 2019. Core aims to enhance biomedical research in Puerto Rico by providing resources for research, education and training. These resources will work to advance these specific aims: 1. enhance biomedical research in PR by providing researchers with the bioinformatics tools and technical support they require to perform cutting-edge biomedical research; 2. enhance the computational biology research environment in Puerto Rico by establishing research collaborations with biomedical, computational and mathematics researchers; 3. enhance multidisciplinary research by developing new courses and educational materials in computational biology, statistics and bioinformatics in collaboration with research faculty and the Science and Technology Competency Enhancement (STCE) Core; 4. enhance research by promoting advanced networking between PRAABRE member institutions, to enable collaborative research on and off the island; 5. enhance biomedical research by promoting effective access to scientific literature and databases for the biomedical researchers in PRAABRE; and 6. enhance biomedical research by enabling effective management of bibliographic information by fostering the use of bibliographic software and applying it to literature searches, articles and references management and manuscript writing.
Proper citation: University of Puerto Rico Biomedical Informatics Research Core (RRID:SCR_010119) Copy
http://upr.eagle-i.net/i/0000012d-1479-c6f4-bc92-16e380000000
Cayo Santiago is one of the world''s most renowned field sites for short term and longitudinal non-human primate studies. Its unique research value consists of:a stable and minimally disrupted long-term population management policy which allows investigators to plan and conduct longitudinal studies, an extensive and detailed computerized demographic database on the colony that provides information on individuals dating back to 1957, and DNA fingerprinting which is applied to confirm maternal and paternal relatedness of individuals.
Proper citation: UPR Cayo Santiago Caribbean Primate Research Center (RRID:SCR_010120) Copy
http://upr.eagle-i.net/i/0000012a-250a-2ace-43fb-601a80000000
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Oligonucleotide synthesis service, Automated DNA sequencing, Genotyping analysis service, Analysis of DNA, RNA or proteins, Microarray service. The long-term goal of the Center for Genomics in Health Disparities and Rare Diseases (CGHDRD) is to provide the critical environment that will enable high quality translational and biomedical research in pharmacogenomics, human genetics and genomics, molecular biology. We aim to develop and strengthen a collaborative research environment by providing research infrastructure that supports the focal areas of research at the University of Puerto Rico Medical Sciences Campus (UPR-MSC), which encompass common diseases such as cancer, neurological and cardiovascular disorders as well as rare disorders, by improving the human and physical resources. The Center focuses these initiatives on externally funded, interdisciplinary, collaborative projects which enhance the quality of translational, biomedical and clinical research at the Medical Sciences Campus linked to health disparities and rare disorders in Puerto Rico and nationally. Collaborations with researchers at institutions outside of Puerto Rico or other RCMI institutions, as well as other academic units in the island and in the UPR system are encouraged. The Center provides the necessary expertise to apply high throughput genotyping, expression profiling and sequencing technologies at the UPR-MSC. Specialized technical staff trains researchers at different levels of their scientific careers in supported technologies. Novel DNA and RNA isolation methodologies are applied to a diverse group of organisms and biological samples for nucleic acids sequence analysis in general.
Proper citation: UPR Center for Genomics in Health Disparities and Rare Disorders (RRID:SCR_010122) Copy
http://www.med.upenn.edu/genetics/dnaseq/index.shtml
Core facility that provides the following services: Large sequencing project support, Sanger sequencing service, High throughput DNA sequencing, Ion Torrent Personal Genome Machine sequencing, Template preparation and purification, Roche 454 sequencing, Sequence analysis and database search support, Construction of targeting vector for gene targeting, Genotyping and Fragment Analysis service, Molecular biology services, Mouse genotyping, and Ion Personal Genome Machine sequencing data analysis. The DNA Sequencing Facility provides long read, automated Sanger sequencing; microsatellite-based genotyping and fragment analysis; plasmid and BAC DNA preparation and purification; and related molecular biological services including PCR, cloning, sub-cloning, site-directed mutagenesis, and preparation of targeting vectors for gene targeting in mice. Core also provides services and support for analysis and interpretation of sequence data as well as the design of approaches to complex sequencing projects. For the last four years the facility has been providing Roche 454 sequencing service that includes library preparation, emulsion PCR and pyrosequencing for both genomic DNA and amplicons.
Proper citation: University of Pennsylvania Genomics Analysis Core (RRID:SCR_011061) Copy
http://nextgen.mgh.harvard.edu
Core facility that provides the following services: NextGen sequencing, Data Analysis. The NextGen Core is a collaboration between the Department of Molecular Biology, the Center for Human Genetics Research, the Center for Computational Biology, and the Executive Committee on Research (ECOR). Currently, the Core operates using a single Ilumina HiSeq instrument, accompanied by Illumina''''s cBot for cluster generation. This upgrade from our Genome Analyzer II doubled our capacity and greatly increased the data amount, quality, and stability over extra-long reads. The Core is located in the state-of-the-art Richard Simches Research Center on Cambridge St. as part of the MGH main campus in Boston. The many multi-investigator groups in the building - including those that study human genetics, stem cells, genomics, and more - make it the perfect location for the Core to service the researchers in those groups. The majority of customers come from MGH, but they also service customers at other academic medical centers and industry.
Proper citation: MGH NextGen Sequencing Core (RRID:SCR_012294) Copy
http://www.mmc.edu/research/centers/research-centers/metrc/core-facilities.html
Core facility that aids investigators and trainees with high performance computation in proteomics, as well as other omics type applications needing efficient analysis of large-scale biological data sets. The ability to incorporate proteomics into translational and clinical biomedical research is critical for the discovery of therapeutic interventions and high fidelity biomarkers of disease and response to therapy. The Core provides state-of-the-art services, training, and bioinformatics-driven data analysis to the Meharry translational research community.
Proper citation: Meharry Proteomics Core (RRID:SCR_012179) Copy
Core facility that positions digital imaging resources right where the research is being done: in Harvard Medical School''s quad-based basic science departments. The convenience of these locations makes it easy for researchers to access digital imaging expertise when faced with research imaging questions. This accessibility and convenience is supplemented by substantial web-based assistance, making Research Imaging Solutions a 24/7 resource. Seminars, Workshops and printed training materials guide faculty, students, post-docs and lab personnel on supported imaging hardware and software products. Supported hardware and software packages includes: Adobe products including Acrobat, Photoshop, and Illustrator; ACD Canvas; Microsoft Office applications including Word, PowerPoint and Excel; film recorders, slide and flatbed scanners, and color output devices such as color laser printers, poster printers and photo quality printers.
Proper citation: HMS Research Imaging Solutions (RRID:SCR_012302) Copy
http://dartmouth.eagle-i.net/i/0000013f-dd9e-c2d6-8fa3-ce9080000000
The SYNERGY Clinical Research Unit (CRU) is an outpatient research support unit that offers investigators a full array of services for the conduct of clinical research. The CRU is available to any Dartmouth faculty or researcher wishing to access dedicated space and staff resources for the efficient conduct of clinical research.
Proper citation: Dartmouth SYNERGY Clinical Research Unit (RRID:SCR_005645) Copy
http://hunter-cuny.eagle-i.net/i/00000136-7eb5-5555-949b-425080000000
Core facility that provides the following services: Training Service, TEM Analysis Service. ?The Nanoscale Analytical Facility is equipped with Jeol 2100 EDAX operated at 200kV. Nanomaterial containing samples of inorganic as well as organic building blocks, macromolecular constructs, metallic nanoparticles, metal oxide nano-powders are often imaged.
Proper citation: Hunter Nanoscale Analytical Facility (RRID:SCR_005617) Copy
http://harvard.eagle-i.net/i/0000012b-00c4-1614-db6e-7a3f80000000
Core facility that provides the following services: Magnetic resonance spectrometer training service, Magnetic Resonance Instrument Access. Welcome to the Magnetic Resonance Facility of the Department of Chemistry and Chemical Biology, Harvard University, in the Laukien-Purcell Instrumentation Center.
Proper citation: Harvard FAS Magnetic Resonance Laboratory (RRID:SCR_008476) Copy
http://www.med.upenn.edu/idom/drc/cores/cellbio.html
Core that gives support including experimental design, islet isolation, and performance of and training in an expansive range of assays for physiological and morphometric assessment of pancreatic islet function and growth. It contributes to the basic and translational research activities of the Institute of Diabetes, Obesity and Metabolism (IDOM) at the Perelman School of Medicine of the University of Pennsylvania. Its services include perform individual islet and single cell fluorescence imaging, respirometry with islet batches using a Seahorse Extracellular Flux Analyzer, perifusion coupled with respirometry, and closed respirometry experiments for our investigators.
Proper citation: University of Pennsylvania School of Medicine Penn Diabetes Research Center Pancreatic Islet Cell Biology Core Facility (RRID:SCR_008265) Copy
http://eagle-i.itmat.upenn.edu/i/00000139-4f55-f0f9-eb5b-b63c80000000
Core facility that provides the following services: Laser confocal microscope access. Penn Dental Medicine houses a Radiance 2100 laser confocal microscope available for use by researchers throughout the School as well as others inside and outside the University.
Proper citation: Penn Laser Confocal Microscope Core (RRID:SCR_009533) Copy
http://harvard.eagle-i.net/i/0000012e-3502-595e-550e-f59280000000
An Core facility
Proper citation: HSPH Organic Chemistry Laboratory (RRID:SCR_008280) Copy
http://harvard.eagle-i.net/i/00000137-e1a0-4fec-d807-77a880000000
The Weld Hill Growth Facilities consist of 12 individually controlled greenhouses and several types of Conviron growth chambers for precise control of growing conditions.
Proper citation: Arnold Arboretum of Harvard University: Weld Hill Growth Facilities (RRID:SCR_009649) Copy
http://www.itmat.upenn.edu/ctsa/acard/
A core facility in the Center for Pharmacoepidemiology Research and Training created to foster epidemiologic research into therapeutics, using large population-based automated claims databases (Medicaid/Medicare) and medical records databases (GPRD and THIN), and the FDA''s adverse event reporting system (FAERS) database. Goals: * Encourage investigators with diverse training to conduct studies focused on translational therapeutics and drug safety * Provide access to large databases that allow for rapid and cost-effective research on therapeutics and drug safety * Foster collaboration with CTSA sites outside of Penn who wish to use these databases for clinical research
Proper citation: Penn Automated Claims and Medical Record Databases (RRID:SCR_009643) Copy
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