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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Flye
 
Resource Report
Resource Website
100+ mentions
Flye (RRID:SCR_017016) data processing software, data analysis software, software resource, sequence analysis software, software application, software toolkit Software package as de novo assembler for single molecule sequencing reads. Used for assembling long, error prone reads such as those produced by PacBio and Oxford Nanopore Technologies, for fast and accurate genome reconstructions. Available for Linux and MacOS platforms. assembler, single, molecule, sequencing, long, error, read, fast, accurate, genome, reconstruction, nucleotide, quality, data, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at San Diego; California; USA
PMID:27956617 Free, Available for download, Freely available biotools:Flye https://bio.tools/Flye, https://sources.debian.org/src/flye/ SCR_017016 2026-08-04 09:44:03 267
CCTOP
 
Resource Report
Resource Website
10+ mentions
CCTOP (RRID:SCR_016963) CCTOP analysis service resource, web service, software resource, data access protocol, production service resource, service resource Web application providing transmembrane topology prediction. Server incorporates topology information from existing experimental and computational sources using the probabilistic framework of hidden Markov model. Provides the option to precede the topology prediction with signal peptide prediction and transmembrane globular protein discrimination. Given the amino acid sequence of a putative α helical transmembrane protein, CCTOP predicts its topology i.e. localization of membrane spanning regions and orientation of segments between them. transmembrane, topology, prediction, signal, peptide, globular, protein, discrimination, amino, acid, sequence, region, orientation, segment, bio.tools is listed by: Debian
is listed by: bio.tools
works with: PDBTM
works with: Topology Data Bank of Transmembrane Proteins
works with: TopDom
Hungarian Scientific Research Fund PMID:25943549 Free, Freely available biotools:cctop https://bio.tools/cctop SCR_016963 CCTOP, Consensus Constrained TOPology 2026-08-04 09:44:01 29
Illuminating the Druggable Genome
 
Resource Report
Resource Website
10+ mentions
Illuminating the Druggable Genome (RRID:SCR_016924) IDG portal, storage service resource, consortium, organization portal, data repository, service resource, data or information resource Program to improve understanding of properties and functions of proteins that are currently unannotated within three most commonly drug protein families: targeted G-protein coupled receptors, ion channels, and protein kinases. Includes Data and Resource Generating Centers (DRGC), Knowledge Management Center (KMC), and Resource Dissemination and Outreach Center (RDOC). understudied, target, protein, G protein, coupled, receptor, ion, channel, kinase, bio.tools is recommended by: National Library of Medicine
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
NIH Common Fund biotools:pharos https://pharos.nih.gov/, https://bio.tools/pharos, https://darkmatter.ucsf.edu/about https://druggablegenome.net SCR_016924 Pharos, Illuminating the Druggable Genome, IDG, Illuminating Druggable Genome 2026-08-04 09:44:01 45
Thunder STORM
 
Resource Report
Resource Website
10+ mentions
Thunder STORM (RRID:SCR_016897) ThunderSTORM data processing software, data analysis software, software resource, software application, software toolkit Software tool for automated processing, analysis, and visualization of data acquired by single molecule localization microscopy methods such as PALM and STORM. ImageJ interactive and modular plugin for SMLM data analysis and super-resolution imaging. automated, processing, analysis, visualization, data, acquired, single, molecule, localization, microscopy, SMLM, imaging, bio.tools is listed by: Debian
is listed by: bio.tools
is a plug in for: ImageJ
Czech Science Foundation ;
Charles University ;
European Regional Development Fund ;
European Social Fund
PMID:24771516 Free, Available for download, Freely available biotools:thunderstorm https://bio.tools/thunderstorm SCR_016897 2026-08-04 09:44:00 42
CRISPR-P
 
Resource Report
Resource Website
10+ mentions
CRISPR-P (RRID:SCR_016941) analysis service resource, web service, software resource, data access protocol, production service resource, service resource Web tool for synthetic single-guide RNA design of CRISPR-system in plants. Allows to search for high specificity Cas9 target sites within DNA sequences of interest, which also provides off-target loci prediction for specificity analyses and marks restriction enzyme cutting site to every sgRNA for further convenient in experiment. synthetic, single, RNA, CRISP, plant, Cas9, target, DNA, sequence, analysis, restriction, enzyme, sgRNA, bio.tools is listed by: Debian
is listed by: bio.tools
National Basic Research Program of China ;
Program for New Century Excellent Talents in University ;
Fundamental Research Funds for the Central Universities
PMID:24719468 Free, Freely available biotools:CRISPR-P https://bio.tools/CRISPR-P SCR_016941 CRISPR-P 2.0, Clustered Regularly Interspaced Short Palindromic Repeats P, CRISPR P 2026-08-04 09:44:02 30
ascat
 
Resource Report
Resource Website
10+ mentions
ascat (RRID:SCR_016868) ASCAT data processing software, software application, software resource, data analysis software Software R package to infer tumor purity, ploidy and allele-specific copy number profiles. It is platform and species independent, and works for both Illumina and Affymetrix SNP arrays, as well as for massively parallel sequencing data. allele, specific, copy, number, analysis, tumor, purity, ploidy, sequencing, data, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:20837533 Free, Available for download, Freely available BioTools:ascat, biotools:ascat https://github.com/VanLoo-lab/ascat, https://www.crick.ac.uk/research/labs/peter-van-loo/software, https://bio.tools/ascat, https://sources.debian.org/src/r-other-ascat/ SCR_016868 ASCAT 3.0, ASCAT 2.0, ASCAT 4.0, ASCAT 1.0, Allele-Specific Copy Number Analysis of Tumors, Allele Specific Copy Number Analysis of Tumors 2026-08-04 09:44:00 33
EMAN
 
Resource Report
Resource Website
100+ mentions
EMAN (RRID:SCR_016867) EMAN data processing software, software application, image processing software, software resource Software suite for processing data from transmission electron microscopes. Used in supercomputing facilities as a test application for large-scale computing. Used for single particle reconstruction, helical reconstruction, 2-D crystallography and whole-cell tomography. image, processing, data, transmission, electron, microscope, single, particle, reconstruction, helical, 2D, whole, cell, tomography, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
NIH PMID:16859925 Free, Available for download, Freely available biotools:eman https://bio.tools/eman https://blake.bcm.edu/emanwiki/EMAN1 SCR_016867 EMAN1, EMAN2 2026-08-04 09:44:00 106
clusterProfiler
 
Resource Report
Resource Website
10000+ mentions
clusterProfiler (RRID:SCR_016884) data processing software, data analysis software, software resource, software application, data visualization software Software R package for statistical analysis and visualization of functional profiles for genes and gene clusters. data, statistical, analysis, visualization, gene, cluster, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
National 973 Projects of China ;
2007 Chang-Jiang Scholars Program ;
National Natural Science Foundation of China ;
Guangdong Natural Science Research Grant ;
Fundamental Research Funds for the Central Universities
PMID:22455463 Free, Available for download, Freely available biotools:clusterprofiler https://github.com/GuangchuangYu/clusterProfiler, https://guangchuangyu.github.io/software/clusterProfiler/, https://bio.tools/clusterprofiler SCR_016884 Cluster Profiler 2026-08-04 09:44:00 10762
QuickNII
 
Resource Report
Resource Website
10+ mentions
QuickNII (RRID:SCR_016854) QuickNII data processing software, registration software, software resource, software application, image processing software, image analysis software Histological brain section series aligner to volumetric atlases. Software tool for user guided affine registration (anchoring) of 2D experimental image data, typically high resolution microscopic images, to 3D atlas reference space, facilitating data integration through standardized coordinate systems. Part of the QUINT workflow. section, series, aligner, volumetric, 3D, atlas, reference, space, anchoring, data, image, microscopic, standardized, coordinate, system, bio.tools is used by: BICCN
is listed by: Debian
is listed by: bio.tools
is listed by: EBRAINS
is related to: LocaliZoom
is related to: Allen Institute for Brain Science
has parent organization: University of Oslo; Oslo; Norway
European Union Horizon 2020 Framework Programme for Research and Innovation under the Framework Partnership Agreement PMID:31141518 Free, Available for download, Freely available biotools:QuickNII https://quicknii.readthedocs.io; https://bio.tools/QuickNII, https://github.com/Tevemadar/QuickNII SCR_016854 2026-08-04 09:44:00 37
Heatmapper
 
Resource Report
Resource Website
100+ mentions
Heatmapper (RRID:SCR_016974) data processing software, web service, software resource, data access protocol, software application Software tool to create and provide heat maps through a graphical interface. Allows to create an expression, pairwise comparison, image overlay, geomap, and geocoordinate heat maps for different data types and applications. Used to interactively visualize data. expression, based, heat, map, pairwise, comparison, distance, correlation, image, overlay, latitude, longitude, geomap, geopolitical, geocoordinate, choropleth, data, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
has parent organization: Wishart Research Group
is provided by: University of Alberta; Alberta; Canada
Canadian Institutes of Health Research ;
Genome Alberta
PMID:27190236 Freely available, Free, Acknowledgement requested OMICS_12077, biotools:heatmapper http://www.heatmapper.ca, https://github.com/WishartLab/heatmapper, https://bio.tools/heatmapper SCR_016974 Heatmapper, HeatMapper, heat mapper 2026-08-04 09:44:01 131
Gigwa
 
Resource Report
Resource Website
1+ mentions
Gigwa (RRID:SCR_017080) data processing software, data analysis software, analysis service resource, data management software, data distribution software, web service, software resource, application programming interface, software application, data access protocol, production service resource, service resource, biomaterial analysis service, material analysis service Web tool to explore genotyping metdata by filtering it on basis of variant features, including functional annotations and matching genotype patterns. May be deployed on workstation or as data portal. Allows to feed MongoDB database with VCF, PLINK or HapMap files and provides interface to filter data in real time. Used to export filtered data into formats and features connectivity with online genomic tools and with standalone software such as FlapJack or IGV. Gigwa hosted datasets are interoperable via two standard REST APIs such GA4GH and BrAPI. metadata, genotyping, filter, variant, functional, annotation, pattern, bio.tools is listed by: Debian
is listed by: bio.tools
UMR DIADE and Agropolis Fundation PMID:27267926 Free, Freely available biotools:Gigwa https://github.com/SouthGreenPlatform/Gigwa2, https://bio.tools/Gigwa SCR_017080 GIGWA, GIGWA2, Genotype Investigator for Genome Wide Analysis 2026-08-04 09:44:06 2
CATALYST
 
Resource Report
Resource Website
100+ mentions
CATALYST (RRID:SCR_017127) data processing software, data analysis software, software resource, software application, software toolkit Software R package to provide pipeline for preprocessing of cytometry data, including normalization using bead standards, single cell deconvolution, and bead based compensation. preprocessing, cytometry, data, normalization, bead, standard, single, cell, deconvulsion, compensation, bio.tools uses: CATALYSTLite
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
Swiss National Science Foundation ;
SNSF Assistant Professorship grant ;
PhosphonetPPM and MetastasiX SystemsX grant ;
NIDDK UC4 DK108132;
European Research Council ;
Roche Postdoctoral Fellowship
PMID:29605184 Free, Available for download, Freely available biotools:catalyst https://github.com/HelenaLC/CATALYST, https://bio.tools/catalyst SCR_017127 Cytometry dATa anALYSis Tools 2026-08-04 09:44:05 223
SwiftOrtho
 
Resource Report
Resource Website
1+ mentions
SwiftOrtho (RRID:SCR_017122) data processing software, software application, software resource, data analysis software Software tool for orthology analysis to identify orthologs, paralogs and co orthologs for genomes. Used to perform homology classification across genomes of different species in large genomic datasets. orthology, analysis, identify, ortholog, paralog, co ortholog, genome, homology, different, species, large, dataset, bio.tools uses: Python Programming Language
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
DOI:10.1101/543223 Free, Available for download, Freely available OMICS_30890, biotools:SwiftOrtho https://bio.tools/SwiftOrtho SCR_017122 2026-08-04 09:44:04 4
Experimental Design Assistant
 
Resource Report
Resource Website
100+ mentions
Experimental Design Assistant (RRID:SCR_017019) EDA web application, software resource, service resource Web based tool to help in vivo researchers improve design, conduct, analysis and reporting of animal experiments.Provides automated feedback on proposed design and generates graphical summary that aids communication with colleagues, founders and regulatory authorities. Addresses causes of irreproducibility. in vivo, design, conduct, analysis, reporting, animal, experiment, irreproducibility, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: NC3Rs
PMID:28957312 Free, Freely available biotools:eda https://bio.tools/eda SCR_017019 EDA, Experimental Design Assistant (EDA), Experimental Design Assistant 2026-08-04 09:44:03 187
ClustVis
 
Resource Report
Resource Website
500+ mentions
Issue
ClustVis (RRID:SCR_017133) data analysis service, analysis service resource, web service, software resource, data access protocol, production service resource, service resource Web user interface for visualizing clustering of multivariate data. Web server allows users to upload their own data and create Principal Component Analysis plots and heatmaps. visualizing, clustering, multivariate, data, principal, component, analysis, plot, heatmap, bio.tools uses: Shiny
uses: ggplot2
uses: pheatmap
uses: RColorBrewer
uses: FactoMineR
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: R Project for Statistical Computing
has parent organization: University of Tartu; Tartu; Estonia
Innovative Medicines Initiative Joint Undertaking ;
European Union Seventh Framework Programme ;
European Federation of Pharmaceutical Industries and Associations ;
European Regional Development Fund ;
Estonian Research Council ;
European Commission ;
EFPIA
PMID:25969447 biotools:clustvis, OMICS_08539 https://github.com/taunometsalu/ClustVis, https://bio.tools/clustvis SCR_017133 2026-08-04 09:44:05 798
Comparative Metatranscriptomics Workflow
 
Resource Report
Resource Website
1+ mentions
Comparative Metatranscriptomics Workflow (RRID:SCR_017109) CoMW data processing software, data analysis software, workflow, software resource, training material, sequence analysis software, software application, narrative resource, data or information resource Software tool for standardized and validated workflow to functionally classify quality filtered mRNA reads from metatranscriptomic or total RNA studies generated using NGS short reads. Used for classification of these reads using assembled contigs to reference databases. workflow, functionally, classify, mRNA, metatranscriptomic, RNA, next, generation, sequencing, NGS, short, read, assembly, contig, reference, database, bio.tools is listed by: bio.tools
is listed by: Debian
h2020 EU MicroArctic ITN Free, Available for download, Freely available biotools:comw https://bio.tools/CoMW SCR_017109 2026-08-04 09:44:04 3
HaTSPiL
 
Resource Report
Resource Website
1+ mentions
HaTSPiL (RRID:SCR_017059) data processing software, data analysis software, software resource, sequence analysis software, software application Software Python tool for high throughput sequencing analysis, focused on high reliability, modularity and customisability. next, generation, sequencing, pipeline, metadata, analysis, mutation, barcoding, customisability, modularity, bio.tools uses: Python Programming Language
is listed by: Debian
is listed by: bio.tools
has parent organization: Italian Institute for Genomic Medicine; Turin; Italy
Free, Available for download, Freely available biotools:HatSPiL https://bio.tools/HaTSPiL SCR_017059 2026-08-04 09:44:04 1
PRSice
 
Resource Report
Resource Website
50+ mentions
PRSice (RRID:SCR_017057) data processing software, software application, software resource, data analysis software Software R package for calculating, applying, evaluating and plotting results of polygenic risk scores analysis. Performs simulation study to estimate P value significance threshold for high resolution PRS studies and produces plots for inspection of results. Operating Unix/Linux. polygenic, risk, score, calculating, applying, plotting, result, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
EU ;
NIHR Biomedical Research Centre
PMID:25550326 Free, Available for download, Freely available OMICS_23656, biotools:prsice https://choishingwan.github.io/PRSice/, https://bio.tools/prsice SCR_017057 prsice, PRSice-2, Polygenic Risk Score software, PRSice1, PRSice2 2026-08-04 09:44:03 97
BinPacker
 
Resource Report
Resource Website
10+ mentions
BinPacker (RRID:SCR_017038) data processing software, software application, software resource, data analysis software Software tool as de novo trascriptome assembler for RNA-Seq data. Used to assemble full length transcripts by remodeling problem as tracking set of trajectories of items over splicing graph. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux. de novo, transcriptome, assembler, RNAseq, data, full, length, transcript, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China ;
NSF 1553680;
NCRR P20 RR01 6460;
NIGMS P20 GM103429
PMID:26894997 Free, Available for download, Freely available OMICS_11199, biotools:binpacker http://sourceforge.net/projects/transcriptomeassembly/files/BinPacker_1.0.tar.gz/download, http://sourceforge.net/projects/transcriptomeassembly/files/BinPacker_binary.tar.gz/download, https://bio.tools/binpacker SCR_017038 2026-08-04 09:44:03 10
PS-Plant Framework
 
Resource Report
Resource Website
1+ mentions
PS-Plant Framework (RRID:SCR_017032) PS-Plant segmentation software, data processing software, code testing framework, data analysis software, time-series analysis software, software development tool, software resource, 3d time-series analysis software, software application, workflow software, image analysis software, image, 2d spatial image, 3d visualization software, data visualization software, data or information resource Software tool as end to end software for data acquisition, processing, and result extraction of Arabidopsis thaliana growth. Framework uses photometric stereo based 3D imaging system with computer vision and deep learning for tracking and quantifying both plant growth and movement parameters. photometric, 3D, imaging, tracking, plant, growth, arabidopsis, thaliana, leaf, angle, segmentation, machine, learning, near-infrared, (NIR), LED, photomorphogenesis, thermomorphogenesis, bio.tools uses: Python Programming Language
is listed by: bio.tools
is listed by: Debian
BBSRC BB/N02334X/1;
BBSRC BB/M025551/1;
BBSRC BB/N005147/1
Free, Available for download, Freely available biotools:PS-Plant https://bio.tools/PS-Plant SCR_017032 2026-08-04 09:44:03 1

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