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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.biotech.cornell.edu/core-facilities-brc/facilities/biomolecular-interactions-properties
Provides investigators with access to advanced tools for measuring biomolecular interactions and properties through variety of techniques from high throughput screening via automation to single reaction cuvette based methods.Facility complements technologies and techniques available through our Imaging facility and Proteomics and Metabolomics facility.
Proper citation: Cornell University Biotechnology Resource Center Biomolecular Interactions and Properties Core Facility (RRID:SCR_023117) Copy
https://chemh.stanford.edu/research/knowledge-centers
Shared resource to provide instrumentation and scientific expertise to Stanford researchers.Each Knowledge Center is organized around specific scientific area and offers services to the research community. Services, advice, training and instrument access, include area in High-Throughput Screening, Medicinal Chemistry, Crystallography, Cryo-EM, Metabolomics, Protein engineering, Protein expression.
Proper citation: Stanford Sarafan Chemistry, Engineering and Medicine for Human Health Knowledge Centers Core Facility (RRID:SCR_023238) Copy
Sequencing Core offers Illumina next generation sequencing services to University of Pittsburgh research community. Offers expertise in next generation sequencing technologies. Encourages to contact Assistant Director to arrange for consultation.Staff is available to share their experience and expertise to assist with development of projects of all sizes, standard or custom assay design, and other specialized application needs.
Proper citation: University of Pittsburgh Medical Center Children Hospital of Pittsburgh Health Sciences Sequencing Core Facility (RRID:SCR_023116) Copy
https://chemh.stanford.edu/research/knowledge-centers/protein-engineering
MSKC is main gateway for Stanford faculty and students interested to study biological molecules using SLAC X-ray facilities and other major bioimaging facilities.
Proper citation: Stanford Sarafan Protein Engineering Knowledge Center Core Facility (RRID:SCR_023237) Copy
https://chemh.stanford.edu/research/knowledge-centers/metabolomics
Provides scientific expertise and instrumentation for measurement of small molecules such as metabolites and lipids to ChEM-H and Stanford communities. Leverages expertise in mass spectrometry and allied techniques to understand biology of small molecules both metabolites and xenobiotics and to apply that understanding to advances in human health.
Proper citation: Stanford Sarafan Metabolomics Knowledge Center Core Facility (RRID:SCR_023236) Copy
Provides equipment and expertise for analysis of variety of biological and small molecules.Services include protein analysis encompassing protein identification, protein and peptide sequence confirmation, intact protein molecular weight determination, complex protein sample analysis, and protein/antibody drug interactions.Developed metabolomics library to support metabolomic and lipidomics analysis. Can identify range of post-translational modifications, determining their presence or absence, as well as quantitating PTMs.Proteomics and small molecule services include workflows for label free,chemical labeling (iTRAQ/TMT) and metabolic labeling (SILAC).Service for molecular synthesis, with monitoring reaction steps,calculating percentage of product, testing for purity, and molecule characterization with high resolution and high mass accuracy.Provides molecular weight and chemical composition determinations, structure elucidations and compound identification analysis or confirmation and accurate mass measurements of synthetic products, measurement of polymers, nucleic acids (DNA/RNA), peptides, proteins, natural products, and assistance with determination of unknowns.
Proper citation: University of Arizona Analytical and Biological Mass Spectrometry Core Facility (RRID:SCR_023370) Copy
http://www.arpege.cnrs.frCore FacilityArpege
Offers functional and structural analysis of protein complexes.Offers possibility to characterize all types of molecular interactions: ligand-target binding, protein-protein interactions, signal transduction, and signalling complexes. Staff members are skilled specialists in luminescence-based techniques and in receptor biology.Application portfolio includes Analysis of cell signalling, by measuring signal transduction;Ligand-target binding (pharmacological analysis, affinity, selectivity); Protein-protein interactions (oligomerization, effectors...); Activation of signalling pathways (G proteins, GRK, arrestins & internalization); Intracellular production of second messengers (cAMP, IP1, Ca2+); Phosphorylation of signalling proteins (ERK, AKT...); Measurement of global cell functions and of different cell parameters (proliferation, migration, invasion...).
Proper citation: Arpege Core Facility (RRID:SCR_023092) Copy
Provides microscopy expertise and access to high resolution, state-of-the-art imaging technologies to Stanford University and surrounding academic and biotech researchers. Core provides training, design, implementation, and analysis assistance.
Proper citation: Stanford Neuroscience Microscopy Service Core Facility (RRID:SCR_023257) Copy
https://www.crg.eu/en/programmes-groups/crgupf-proteomics-unit
Proteomics Unit is joint effort of Universitat Pompeu Fabra and Center of Genomic Regulation. Provides proteomics services by offering state-of-the-art methods, advise and expertise to support basic and translational researchers; developing new methods and techniques that keep the unit up to date and at the forefront of the proteomics field; training community and actively disseminating proteomics science and methods.Part of Spanish National Infrastructure for Omics Technologies and European Proteomics Infrastructure Consortium, and it coordinates European innovative and interdisciplinary Research and Training network. The Proteomics Unit is also part of Spanish National Health System.
Proper citation: Centre for Genomic Regulation Proteomics Unit Core Facilitiy (RRID:SCR_023377) Copy
Provides preclinical Magnetic Resonance Imaging technology and expertise to Stanford community. Offers range of support from full project to independent user operation and training.
Proper citation: Stanford Neuroscience Preclinical Imaging Laboratory Core Facility (RRID:SCR_023254) Copy
https://geochronology.stanford.edu/
Core for comprehensive examination of evolution of Earth's crust using geochronologic approaches. Provides spectrum of analytical facilities that are all housed within School of Earth, Energy and Environmental Sciences.Provides data to many disciplines throughout geosciences, including tectonics, geodynamics, petrology, geochemistry, geomorphology, sedimentology, stratigraphy, paleontology, and paleoclimatology.
Proper citation: Stanford Geochronology Cluster Core Facility (RRID:SCR_023252) Copy
https://www.crg.eu/en/programmes-groups/bioinformatics-unit
Provides services of consultation, planning NGS and other genomic experiments, NGS data processing, analysis and management, software and database development, bioinformatics training, and access to high-performance computing resources at CRG. The Unit works in synergy with the Genomics Unit and the Biomolecular Screening and Protein Technologies Unit to support users using high throughput sequencing technologies from experiment planning to delivery of timely and reliable results.
Proper citation: Centre for Genomic Regulation Bioinformatics Unit Core Facility (RRID:SCR_023373) Copy
https://www.rockefeller.edu/crispr/
Provides gene targeting and mouse embryonic stem cell technology for members of Rockefeller University, Memorial Sloan-Kettering Cancer Center and their collaborators.CRISPR and Genome Editing services include mouse genomic knock-out and knock-in, mouse conditional knock-out, establishing new ES lines for gene targeting services, establishing ES lines from mutant mouse embryos, preparing ES cells introduced from off campus resources for injection or other application, assisting in embryoid body culture and in vitro differentiation of ES cells, and purification and evaluation of DNA for pronuclear injection.
Proper citation: Rockefeller University CRISPR and Genome Editing Resource Center Core Facility (RRID:SCR_023097) Copy
https://www.crg.eu/en/programmes-groups/advanced-light-microscopy-unit
Core provides support with experimental design, sample preparation, acquisition, bioimage analysis and visualization.Consists of microscope systems specifically designed for fluorescence microscopy ranging from confocal, widefield to super resolution systems and helps reveal structures from macro to nanoscale.
Proper citation: Centre for Genomic Regulation Advanced Light Microscopy Unit Core Facility (RRID:SCR_023371) Copy
http://web.stanford.edu/~profitt/
Core for assisting with custom instrumentation and equipment needs at affordable price.Projects devices include microcontrollers, LCD displays, keypad interfaces, serial communication, signal conditioning electronics, analog and digital computer interfaces, photomultiplier tube amplifiers, DC motor, stepper motor and linear motor controllers, servomotors, rotary encoders, timed sequenced equipment, temperature controllers, peltier devices, solenoid valves, actuators, force transducers, profusion chambers, microscope adapters as well as mechanical design and limited machine shop services.
Proper citation: Stanford University Instrumentation Shop Core Facility (RRID:SCR_023408) Copy
https://cyclotron.stanford.edu/
Provides clinical and pre-clinical radiotracers for understanding and detecting cancer, cardiac conditions, inflammatory disorders, and neurodegenerative diseases.
Proper citation: Stanford University Cyclotron and Radiochemistry Core Facility (RRID:SCR_023407) Copy
Provides variety of Macintosh, Windows, and Linux software for scientific research.Obtains concurrent network licenses that work under control of software license manager.This allows facility to purchase limited number of copies of expensive software and distribute software within Stanford network.CSBF has user community of over 200 research labs in 36 different departments at Stanford. Staff members have many years of experience in providing computer support to biomedical researchers.
Proper citation: Stanford University School of Medicine Computational Services and Bioinformatics Core Facility (RRID:SCR_023404) Copy
Laboratory at Wu Tsai Neursciences Institute provides preclinical discovery platform for central nervous system target validation in preclinical in vivo and in vitro models. Neurobehavioral assessment tools in CNS disease models provide platform for screening and profiling of experimental therapeutics and genetic rodent models. Used to support understanding of human CNS disorders and development of therapeutic interventions.
Proper citation: Stanford Behavioral and Functional Neuroscience Laboratory Core Facility (RRID:SCR_023249) Copy
Small animal imaginig service center.Instruments range from systems typically found in clinical setting, but scaled for rodent usage (such as MRI, PET, CT and ultrasound), optical systems for measuring bioluminescence, fluorescence, and Cherenkov light (IVIS, Ami, Lago and Maestro systems), new modalities (MPI and photoacoustic), as well as access to advanced image analysis software, computer workstations, and surgical preparation areas. Scientists are trained to use instruments independently and can schedule studies as needed.
Proper citation: Stanford University School of Medicine Center for Innovation in In vivo Imaging Core Facility (RRID:SCR_023345) Copy
https://med.stanford.edu/lucasmri.html
Houses four whole-body MRI systems (three 3.0T, one 7.0T). 3T2 and 3T3 are part of the Lucas Service Center. Individual researchers are trained in magnet safety and scanner operations by the magnet manager or MR research technologists.
Proper citation: Stanford University School of Medicine Richard M. Lucas Center for Imaging Core Facility (RRID:SCR_023344) Copy
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