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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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ProOpDB Resource Report Resource Website 10+ mentions |
ProOpDB (RRID:SCR_006111) | ProOpDB | data or information resource, database | The Prokaryotic Operon DataBase (ProOpDB) constitutes one of the most precise and complete repository of operon predictions in our days. Using our novel and highly accurate operon algorithm, we have predicted the operon structures of more than 1,200 prokaryotic genomes. ProOpDB offers diverse alternatives by which a set of operon predictions can be retrieved including: i) organism name, ii) metabolic pathways, as defined by the KEGG database, iii) gene orthology, as defined by the COG database, iv) conserved protein motifs, as defined by the Pfam database, v) reference gene, vi) reference operon, among others. In order to limit the operon output to non-redundant organisms, ProOpDB offers an efficient protocol to select the more representative organisms based on a precompiled phylogenetic distances matrix. In addition, the ProOpDB operon predictions are used directly as the input data of our Gene Context Tool (GeConT) to visualize their genomic context and retrieve the sequence of their corresponding 5�� regulatory regions, as well as the nucleotide or amino acid sequences of their genes. The prediction algorithm The algorithm is a multilayer perceptron neural network (MLP) classifier, that used as input the intergenic distances of contiguous genes and the functional relationship scores of the STRING database between the different groups of orthologous proteins, as defined in the COG database. Nevertheless, the operon prediction of our method is not restricted to only those genes with a COG assignation, since we successfully defined new groups of orthologous genes and obtained, by extrapolation, a set of equivalent STRING-like scores based on conserved gene pairs on different genomes. Since the STRING functional relationships scores are determined in an un-bias manner and efficiently integrates a large amount of information coming from different sources and kind of evidences, the prediction made by our MLP are considerably less influenced by the bias imposed in the training procedure using one specific organism. | genome, operon, gene pair, gene, operon prediction, metabolic pathway, gene orthology, conserved protein motif, protein motif, reference gene, reference operon, visualization, regulatory region, nucleotide, amino acid, sequence, phylogeny, FASEB list |
is related to: COG is related to: KEGG is related to: Pfam has parent organization: National Autonomous University of Mexico; Mexico City; Mexico |
CONACyT 60127-Q; CONACyT SALUD-2007-C01-68992; DGAPA IN212708 |
PMID:20385580 | nlx_151585 | SCR_006111 | Prokaryotic Operon DataBase (ProOpDB), Prokaryotic Operon DataBase | 2026-08-29 11:29:46 | 35 | ||||||
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PRED-CLASS Resource Report Resource Website |
PRED-CLASS (RRID:SCR_006216) | PRED-CLASS | analysis service resource, data analysis service, production service resource, service resource | A system of cascading neural networks that classifies any protein, given its amino acid sequence alone, into one of four possible classes: membrane, globular, fibrous, mixed. | classification, protein, fibrous, globular, protein class, membrane, sequence, algorithm, protein classification, neural network, transmembrane, genome annotation, genome-wide analysis |
is related to: DAM-Bio has parent organization: University of Athens Biophysics and Bioinformatics Laboratory |
European Union ERBFMRXCT960019 | PMID:11455609 | nlx_151762 | SCR_006216 | PRED-CLASS - Classification of proteins into one of four possible classes | 2026-08-29 11:29:46 | 0 | ||||||
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GENCODE Resource Report Resource Website 5000+ mentions Rating or validation data |
GENCODE (RRID:SCR_014966) | data or information resource, dataset, portal, project portal | Human and mouse genome annotation project which aims to identify all gene features in the human genome using computational analysis, manual annotation, and experimental validation. | human, mouse, genome, annotation, sequence, gene features, bio.tools |
is listed by: Debian is listed by: bio.tools is affiliated with: ENCODE |
NHGRI 5U54HG004555; Wellcome Trust WT098051 |
PMID:22955987 | Free | biotools:GENCODE | https://bio.tools/GENCODE | SCR_014966 | ENCODE | 2026-08-29 11:28:44 | 8811 | |||||
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Center for Computational Biology at JHU Resource Report Resource Website 1+ mentions |
Center for Computational Biology at JHU (RRID:SCR_016680) | CCB at JHU | data or information resource, organization portal, portal | Center for Computational Biology as a joint research center in the McKusick-Nathans Institute of Genetic Medicine, spanning the School of Medicine, the Whiting School of Engineering, the Bloomberg School of Public Health, and the Krieger School of Arts & Sciences. Multidisciplinary center dedicated to research on genomics, genetics, DNA sequencing technology, and computational methods for DNA and RNA sequence analysis. | center, computational, biology, genomics, genetics, DNA, RNA, sequence, technology, analysis |
has parent organization: Johns Hopkins University; Maryland; USA is parent organization of: Centrifuge Classifier |
SCR_016680 | CCB at Johns Hopkins University, CCB at JHU, Center for Computational Biology at JHU, Center for Computational Biology at Johns Hopkins University | 2026-08-29 11:28:51 | 1 | |||||||||
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tbl2asn Resource Report Resource Website 10+ mentions |
tbl2asn (RRID:SCR_016636) | data processing software, software application, software resource | Software tool as a command-line program that automates the creation of sequence records for submission to GenBank. Records need no additional manual editing before submission. | command, line, program, automate, creation, sequence, record, submit, data, GenBank | has parent organization: NCBI | Free, Freely available | SCR_016636 | 2026-08-29 11:28:57 | 11 | ||||||||||
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Gene-conservation-informed-contig-alignment Resource Report Resource Website 1+ mentions |
Gene-conservation-informed-contig-alignment (RRID:SCR_017617) | GCICA | data processing software, software application, software resource | Software tool for separation haplotigs from genome assembly. Method to separate haplotigs based on sequence similarity. | Separation, haplotig, genome, assembly, sequence, similarity | Free, Available for download, Freely available | SCR_017617 | 2026-08-29 11:28:59 | 1 | ||||||||||
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Invitrogen Clones Resource Report Resource Website 1+ mentions |
Invitrogen Clones (RRID:SCR_005371) | Invitrogen Clones | biomaterial supply resource, material resource | The Invitrogen Clone Collection: * Ultimate ORF Clones: Full-insert sequenced human and mouse open reading frames (ORFs) in a Gateway entry vector offering the highest utility for your downstream analysis needs. * GeneStorm Clones: GeneStorm Clones are human ORFs cloned and tested for expression in a mammalian, insect, or bacterial expression system. They are sequenced for identity and classification and are not guaranteed at the nucleotide level. * Full-Length Clones: An unparalleled repository of clones enriched for full-length inserts, derived from both public and proprietary sources. * BAC/PAC Clones: Invitrogen offers several genomic libraries from a selection of tissues and sources to facilitate your research and discovery. These collections are available in a variety of formats including clones, plates, pools and high-density colony membrane filters. * Yeast Deletions: Each yeast deletion represents a unique gene-knockout of the S. cerevisiae genome. Each open reading frame is knocked out using a PCR-based gene deletion strategy. Yeast deletions are available as clones, pools, plates and complete collections. * Yeast GFP Clones: The Yeast GFP Clone Collection of S. cerevisiae tagged open reading frames were generated by Dr. Erin O''Shea and Dr. Jonathan Weissman at University of California-San Francisco. The GFP fusion proteins are integrated into the yeast chromosome through homologous recombination and are expressed using endogenous promoters. | open reading frame, sequence, full-length clone, bac/pac clone, clone, yeast deletion clone, yeast gfp clone, yeast |
is related to: Xenopus Gene Collection is related to: Mammalian Gene Collection has parent organization: Life Technologies |
nlx_144443 | SCR_005371 | 2026-08-29 11:31:00 | 2 | |||||||||
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VAGrENT Resource Report Resource Website 10+ mentions |
VAGrENT (RRID:SCR_005180) | VAGrENT | software resource, software toolkit | Software tool set for calculating the biological consequences of genomic variations. The suite of perl modules compares genomic variations with reference genome annotations and generates the possible effects each variant may have on the transcripts it overlaps. It evaluates each variation/transcript combination and describes the effects in the mRNA, CDS and protein sequence contexts. It provides details of the sequence and position of the change within the transcript / protein as well as Sequence Ontology terms to classify its consequences. | perl, genomic variation, transcript, mrna, cds, protein sequence, protein, sequence |
is listed by: OMICtools is related to: SO has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom |
OMICS_00192 | SCR_005180 | VAGrENT: Variation Annotation Generator, Variation Annotation Generator | 2026-08-29 11:31:00 | 17 | ||||||||
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TraDES Resource Report Resource Website 1+ mentions |
TraDES (RRID:SCR_006142) | TraDES | software application, software resource | With Trajectory Directed Ensemble Sampling (TraDES) create large ensembles of high-quality protein structures quickly, ranging from near-native to partially unfolded to intrinsically unfolded. TraDES is a system for directly controlling and sampling protein conformational space. TraDES has been previously used for measuring the vastness of protein conformational space and testing the hypothesis of a brute force solution to the protein folding problem. Over 10 Billion protein structures have been produced by TraDES software in previous distributed computing experiments. The package is comprised of binary executable programs and accessory programs and scripts as well as protein structure data files that map out protein conformational space in a probabilistic way. The main programs are: * trades - generates protein structures following the Trajectory Distribution (see below) * seq2trj - makes Trajectory Distributions from sequences for sampling * str2tr - makes Trajectory Distributions from 3D structures for sampling Trajectory Distributions - Controlling the Sampling of Conformational Space The concept of the trajectory distribution may be new to many protein scientists. A trajectory distribution is simply a map of available conformational space at an amino acid residue. NMR scientists are the primary users of the TraDES package. | protein, protein structure, structure, trajectory, sequence, protein folding | has parent organization: Christopher Hogues Research Lab at the National University of Singapore | PMID:11746699 PMID:10737933 |
Open-source | nlx_151632 | SCR_006142 | Trajectory Directed Ensemble Sampling, TraDES - Trajectory Directed Ensemble Sampling | 2026-08-29 11:30:58 | 8 | ||||||
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ProP Server Resource Report Resource Website 50+ mentions |
ProP Server (RRID:SCR_014936) | software resource, web application | Web application which predicts arginine and lysine propeptide cleavage sites in eukaryotic protein sequences using an ensemble of neural networks. Furin-specific prediction is the default. It is also possible to perform a general proprotein convertase prediction. | web application, prediction, arginine, lysine, cleavage, propeptide, eukaryotic, protein, sequence, bio.tools |
is listed by: Debian is listed by: bio.tools |
DOI:10.1093/protein/gzh013 | Open source | biotools:prop, BioTools:prop | https://bio.tools/prop, https://bio.tools/prop, https://bio.tools/prop | SCR_014936 | ProP, ProP 1.0 Server, ProP 1.0 | 2026-08-29 11:28:17 | 78 | ||||||
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SeqEM Resource Report Resource Website 1+ mentions |
SeqEM (RRID:SCR_002021) | algorithm resource, data analysis software, data processing software, sequence analysis software, software application, software resource, web application | Online tool for utilizing a genotype calling algorithm for next-generation sequence data. | genotype, algorithm, sequence, rna, dna, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian has parent organization: University of Miami Miller School of Medicine; Florida; USA |
PMID:20861027 | THIS RESOURCE IS NO LONGER IN SERVICE | OMICS_00074, biotools:seqem | https://bio.tools/seqem | SCR_002021 | 2026-08-29 11:27:35 | 1 | |||||||
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RNA Ontology Resource Report Resource Website 1+ mentions |
RNA Ontology (RRID:SCR_003470) | RNAO | controlled vocabulary, data or information resource, ontology | An ontology to capture all aspects of RNA - from primary sequence to alignments, secondary and tertiary structure from base pairing and base stacking to sophisticated motifs. | owl, obo, molecular structure, molecular, rna, sequence, alignment, structure, base pairing, base stacking, motif |
is listed by: BioPortal is listed by: OBO is listed by: Google Code |
Free, Available for download, Freely available | nlx_157566 | http://purl.bioontology.org/ontology/RNAO, http://rnao.googlecode.com/svn/trunk/rnao.obo | SCR_003470 | 2026-08-29 11:27:41 | 1 | |||||||
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Influenza Ontology Resource Report Resource Website |
Influenza Ontology (RRID:SCR_003346) | FLU | controlled vocabulary, data or information resource, ontology | An application ontology established by a collaborative group of influenza researchers that includes consolidated influenza sequence and surveillance terms from resources such as the BioHealthBase (BHB), a Bioinformatics Resource Center (BRC) for Biodefense and Emerging and Re-emerging Infectious Diseases, the Centers for Excellence in Influenza Research and Surveillance (CEIRS) | owl, health, pathological, organismal, cellular, sequence, surveillance |
is listed by: BioPortal is listed by: OBO is related to: Information Artifact Ontology has parent organization: University of Maryland; Maryland; USA |
Influenza | Free, Freely available | nlx_157440 | http://purl.obolibrary.org/obo/flu.owl, http://influenzaontologywiki.igs.umaryland.edu/ | http://purl.bioontology.org/ontology/FLU | SCR_003346 | 2026-08-29 11:27:32 | 0 | |||||
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COnsensus-DEgenerate Hybride Oligonucleotide Primers Resource Report Resource Website 1+ mentions |
COnsensus-DEgenerate Hybride Oligonucleotide Primers (RRID:SCR_002875) | analysis service resource, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource | This COnsensus-DEgenerate Hybrid Oligonucleotide Primer (CODEHOP) strategy has been implemented as a computer program that is accessible over the World-Wide Web and is directly linked from the BlockMaker multiple sequence alignment site for hybrid primer prediction beginning with a set of related protein sequences. This is a new primer design strategy for PCR amplification of unknown targets that are related to multiply-aligned protein sequences. Each primer consists of a short 3' degenerate core region and a longer 5' consensus clamp region. Only 3-4 highly conserved amino acid residues are necessary for design of the core, which is stabilized by the clamp during annealing to template molecules. During later rounds of amplification, the non-degenerate clamp permits stable annealing to product molecules. The researchers demonstrate the practical utility of this hybrid primer method by detection of diverse reverse transcriptase-like genes in a human genome, and by detection of C5 DNA methyltransferase homologs in various plant DNAs. In each case, amplified products were sufficiently pure to be cloned without gel fractionation. Sponsors: This work was supported in part by a grant from the M. J. Murdock Charitable Trust and by a grant from NIH. S. P. is a Howard Hughes Medical Institute Fellow of the Life Sciences Research Foundation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 15,2026. | fractionation, gel, 3', amplification, clone, dna, genome, homolog, human, hybrid, molecule, oligonucleotide, pcr, plant, primer, protein, sequence, transcriptase-methyltransferase |
is related to: OMICtools has parent organization: University of Washington; Seattle; USA |
THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-25557 | SCR_002875 | CODEHOP | 2026-08-29 11:27:32 | 8 | ||||||||
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LAST Resource Report Resource Website 100+ mentions |
LAST (RRID:SCR_006119) | LAST | analysis service resource, data analysis service, data processing software, production service resource, service resource, software application, software resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for aligning sequences, similar to BLAST 2 sequences that colour-codes the alignments by reliability. Another useful feature of LAST is that it can compare huge (vertebrate-genome-sized) datasets. Unfortunately, this only applies to the downloadable version of LAST, not the web service. The web service can just about handle bacterial genomes, but it will take a few minutes and the output will be large. LAST can: * Handle big sequence data, e.g: ** Compare two vertebrate genomes ** Align billions of DNA reads to a genome * Indicate the reliability of each aligned column. * Use sequence quality data properly. * Compare DNA to proteins, with frameshifts. * Compare PSSMs to sequences * Calculate the likelihood of chance similarities between random sequences. LAST cannot (yet): * Do spliced alignment., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | sequence alignment, align, vertebrate, genome, sequence, alignment, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian is related to: RecountDB has parent organization: National Institute of Advanced Industrial Science and Technology |
National Genome Research Network ; INTEuropean Union Systems Institute ; Japanese Ministry of Education Culture Sports Science and Technology MEXT |
PMID:21209072 PMID:20144198 PMID:20110255 DOI:10.1093/nar/gkq010 |
THIS RESOURCE IS NO LONGER IN SERVICE | nlx_151594, OMICS_15813, biotools:last | https://bio.tools/last, https://sources.debian.org/src/last-align/ | SCR_006119 | 2026-08-29 11:27:48 | 403 | |||||
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FASTA Resource Report Resource Website 500+ mentions |
FASTA (RRID:SCR_011819) | FASTA | data analysis software, data processing software, sequence analysis software, software application, software resource | Software package for DNA and protein sequence alignment to find regions of local or global similarity between Protein or DNA sequences, either by searching Protein or DNA databases, or by identifying local duplications within a sequence. | sequence, alignment, DNA, protein, similarity, searching |
is listed by: OMICtools is listed by: SoftCite has parent organization: European Bioinformatics Institute |
Free, Freely available | OMICS_00994 | SCR_011819 | Federal Acquisition STreamlining Act | 2026-08-29 11:27:38 | 896 | |||||||
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DOLOP: A Database of Bacterial Lipoproteins Resource Report Resource Website 10+ mentions |
DOLOP: A Database of Bacterial Lipoproteins (RRID:SCR_013487) | data or information resource, data repository, database, service resource, storage service resource | DOLOP is an exclusive knowledge base for bacterial lipoproteins by processing information from 510 entries to provide a list of 199 distinct lipoproteins with relevant links to molecular details. Features include functional classification, predictive algorithm for query sequences, primary sequence analysis and lists of predicted lipoproteins from 43 completed bacterial genomes along with interactive information exchange facility. This website along will have additional information on the biosynthetic pathway, supplementary material and other related figures. DOLOP also contains information and links to molecular details for about 278 distinct lipoproteins and predicted lipoproteins from 234 completely sequenced bacterial genomes. Additionally, the website features a tool that applies a predictive algorithm to identify the presence or absence of the lipoprotein signal sequence in a user-given sequence. The experimentally verified lipoproteins have been classified into different functional classes and more importantly functional domain assignments using hidden Markov models from the SUPERFAMILY database that have been provided for the predicted lipoproteins. Other features include: primary sequence analysis, signal sequence analysis, and search facility and information exchange facility to allow researchers to exchange results on newly characterized lipoproteins. | figure, functional, algorithm, analysis, bacterial, biosynthetic, classification, genome, lipid, lipoprotein, modification, molecular, molecule, pathogenesis, predictive, primary, prokaryote, query, sequence, signal | has parent organization: University of Cambridge; Cambridge; United Kingdom | nif-0000-21124 | SCR_013487 | DOLOP | 2026-08-29 11:24:32 | 16 | |||||||||
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A plasmid Editor Resource Report Resource Website 100+ mentions |
A plasmid Editor (RRID:SCR_014266) | ApE | data analysis software, data processing software, sequence analysis software, software application, software resource, standalone software | Software tool for plasmid and sequence editing, annotating and drawing plasmid sequences. Used to view circular or linear maps of DNA sequences. Users can perform virtual digests whereby they select predefined DNA ladder, or specify their own, and visualize theoretical DNA fragments. Used to highlight restriction sites in editing window, accurately reflect Dam/Dcm blocking of enzyme sites, highlighting and drawing graphic maps using feature annotations from genbank and embl files, highlighting text using pre-defined and custom feature libraries, and directly BLASTing selected sequence at NCBI or Wormbase. Runs across Windows, OS X, and Linux/Unix. | Plasmid, editing, sequence, annotating, drawing, restriction, site, enzyme, map, DNA, fragment |
works with: GenBank works with: NCBI works with: WormBase |
Free, Available for download, Freely available | https://jorgensen.biology.utah.edu/wayned/ape/ | http://ape-a-plasmid-editor.wikispaces.com | SCR_014266 | A plasmid Editor | 2026-08-29 11:24:47 | 114 | ||||||
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Multiple Mapping Method Server Resource Report Resource Website 1+ mentions |
Multiple Mapping Method Server (RRID:SCR_018015) | MMM server | alignment software, data access protocol, data processing software, image analysis software, service resource, software application, software resource, web service | Web server for modeling protein structure by using Multiple Mapping Method. Approach to sequence-to-structure alignment in comparative protein structure modeling. | Modeling protein structure, multiple mapping method, sequence, structure, alignment, comparative protein structure | PMID:16437570 | Free, Freely available | SCR_018015 | Multiple Mapping Method server | 2026-08-29 11:25:52 | 3 | ||||||||
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MUMmer Resource Report Resource Website 500+ mentions |
MUMmer (RRID:SCR_018171) | alignment software, data processing software, image analysis software, software application, software resource | Software package as system for rapidly aligning entire genomes. Alignment tool for DNA and protein sequences. Can align incomplete genomes. | Align, genome, DNA, protein, sequence, , bio.tools |
is listed by: bio.tools is listed by: Debian is listed by: OMICtools is listed by: SoftCite is related to: MUMmerGPU |
NIAID N01 AI15447; NLM R01 LM06845; NSF IIS 9902923 |
PMID:14759262 | Free, Available for download, Freely available | OMICS_14554, biotools:mummer | https://github.com/mummer4/mummer, https://bio.tools/mummer, https://sources.debian.org/src/mummer/ | SCR_018171 | MUMmer4, MUMmer 3.0 | 2026-08-29 11:26:05 | 547 |
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