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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
HistoAtlas
 
Resource Report
Resource Website
HistoAtlas (RRID:SCR_028056) data or information resource, atlas Pan-cancer morphology atlas linking histological features to molecular and clinical outcomes. Structured way to explore cancer morphology at scale and connect tissue organization with patient outcomes and molecular signatures, enabling translational researchers to systematically discover and evaluate pathology-based biomarkers. Pan-cancer morphology atlas, histological features, molecular and clinical outcomes, Free, Freely available SCR_028056 2026-08-09 09:09:36 0
compareGroups
 
Resource Report
Resource Website
1+ mentions
compareGroups (RRID:SCR_027994) software toolkit, software resource Software R package to create tables displaying results of univariate analyses, stratified or not by categorical variable groupings. create tables, displaying results, univariate analyses, categorical variable groupings, Free, Available for download, Freely available https://github.com/isubirana/compareGroups SCR_027994 2026-08-09 09:09:49 1
Poly Pipeline
 
Resource Report
Resource Website
Poly Pipeline (RRID:SCR_027993) software application, software resource Software data analysis pipeline for spatial transcriptomics data tailored to polyploid organisms. Spatial transcriptomics data, polyploid organisms, data analysis, Free, Available for download, Freely available https://zenodo.org/records/18655692 SCR_027993 2026-08-09 09:09:34 0
Brain Connectivity Toolbox
 
Resource Report
Resource Website
100+ mentions
Brain Connectivity Toolbox (RRID:SCR_004841) BCT software toolkit, software resource A large selection of complex network measures in Matlab that are increasingly used to characterize structural and functional brain connectivity datasets. Several people have contributed to the toolbox, and if you wish to contribute with a new function or set of functions, please contact Olaf Sporns. All efforts have been made to avoid errors, but users are strongly urged to independently verify the accuracy and suitability of toolbox functions for the chosen application. Please report bugs or substantial improvements. brain, connectivity, matlab, brain network, c++, structure, function, brain connectivity, matlab, magnetic resonance, os independent, statistical operation is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Human Connectome Coordination Facility
is related to: Graphtools
has parent organization: Indiana University; Indiana; USA
CSIRO ICT Centre scholarship ;
J.S. McDonnell Foundation Brain NRG JSMF22002082
PMID:19819337 nlx_143925 http://www.nitrc.org/projects/bct SCR_004841 2026-08-09 09:04:09 370
splitneuron
 
Resource Report
Resource Website
splitneuron (RRID:SCR_005001) software application, software resource A database-based neuron simulation tool. An innovative approach to large-scale, biologically plausible, neural-network simulation library. Based on data structures and methods directly coded into database, information flow implying separation of data representing neurons, conceived to share load on multiple machines and calibrating operational load on each machine. nlx_95900 SCR_005001 splitneuron library 2026-08-09 09:04:01 0
DISCO
 
Resource Report
Resource Website
100+ mentions
DISCO (RRID:SCR_004586) DISCO service resource, software resource DISCO is an information integration approach designed to facilitate interoperation among Internet resources. It consists of a set of tools and services that allows resource providers who maintain information to share it with automated systems such as NIF. NIF is then able to harvest the information and keep those sets of information up-to-date. How is this accomplished? By using a series of files and/or scripts which are then placed in the root directory of the resource developer''s resource. (NIF can also host the files on its servers and crawl for changes there.) Once the files of the resource providers are in place, and DISCO is notified, the DISCO server can then recognize and consume the information shared, providing machine understandable information to NIF Integrator Servers (also known as Aggregators) about your resource. What can DISCO do for my resource? * Inform search engines about your resource and keep your NIF Registry resource description up-to-date. * Expose your data (semi-structured datasets or fields within your structured database) through NIF''s Data Federation you choose what data will be shared. * Create links from an NCBI database (e.g., PubMed, Protein, Nucleotide, etc.) to your data records in NIF using Entrez LinkOut. * Advertise your terminology or ontological information. * Share your resource''s news with the NIF community., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. interoperation, sitemap, linkout, news, harvest, aggregate, FASEB list is used by: NIF Data Federation
has parent organization: Neuroscience Information Framework
has parent organization: Yale School of Medicine; Connecticut; USA
NIH PMID:20387131
PMID:18975149
THIS RESOURCE IS NO LONGER IN SERVICE nlx_143827 SCR_004586 registration and interoperation framework, DISCO: Extensible Web resource DISCOvery 2026-08-09 09:03:55 332
MAKER
 
Resource Report
Resource Website
1000+ mentions
MAKER (RRID:SCR_005309) software toolkit, software resource Software genome annotation pipeline. Portable and easily configurable genome annotation pipeline. Used to allow smaller eukaryotic and prokaryotic genomeprojects to independently annotate their genomes and to create genome databases. MAKER identifies repeats, aligns ESTs and proteins to genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence based quality values. gene prediction, genome annotation, identifies repeats, aligns ESTs and proteins to genome, data management, genome annotation, annotation, curation, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
is related to: MAKER Web Annotation Service
has parent organization: University of Utah; Utah; USA
PMID:25501943 SCR_023883, nlx_144363, biotools:maker https://bio.tools/maker, https://github.com/Yandell-Lab/maker SCR_005309 Maker2, maker 2026-08-09 09:04:13 1519
Alien hunter
 
Resource Report
Resource Website
1+ mentions
Alien hunter (RRID:SCR_004575) software application, software resource Alien_hunter is an application for the prediction of putative Horizontal Gene Transfer (HGT) events with the implementation of Interpolated Variable Order Motifs (IVOMs). This program is free software; you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation; either version 2 of the License, or (at your option) any later version. An IVOM approach exploits compositional biases using variable order motif distributions and captures more reliably the local composition of a sequence compared to fixed-order methods. Optionally the predictions can be parsed into a 2-state 2nd order Hidden Markov Model (HMM), in a change-point detection framework, to optimize the localization of the boundaries of the predicted regions. The predictions (embl format) can be automatically loaded into the freely available Artemis genome viewer. is listed by: SoftCite
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:16837528 nlx_56835 SCR_004575 Alien_hunter: Interpolated Variable Order Motifs for Identification of Horizontally Acquired DNA 2026-08-09 09:04:07 3
TDTPOWER
 
Resource Report
Resource Website
TDTPOWER (RRID:SCR_005021) TDTPOWER software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5th,2023. Software application that calculates the sample size required for obtaining a prescribed power against a specified alternative for TDT. (entry from Genetic Analysis Software) gene, genetic, genomic, sas macro is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154678 SCR_005021 2026-08-09 09:04:01 0
FSST - Functional Similarity Search Tool
 
Resource Report
Resource Website
FSST - Functional Similarity Search Tool (RRID:SCR_005819) FSST software application, software resource The Functional Similarity Search Tool (FSST) has been implemented for comparing user defined sets of annotated entities. FSST supports the computation of functional similarity scores based on an individual ontology and of combined scores. Its multi-threaded Java implementation takes advantage of symmetric multi-processing computers, decreasing runtime considerably. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible other analysis, functional similarity search, annotation, ontology, java, training tools is listed by: 3DVC
is listed by: Gene Ontology Tools
is related to: Gene Ontology
is related to: GOTaxExplorer
has parent organization: Max-Planck-Institute for Informatics; Saarbrucken; Germany
BMBF 016R0453;
DFG KFO 129/1-1;
European Union F6 contract LSHG-CT-2003-503265
PMID:17346342 Free for academic use nlx_149320 SCR_005819 Functional Similarity Search Tool (FSST), Functional Similarity Search Tool 2026-08-09 09:04:16 0
Eigensoft
 
Resource Report
Resource Website
1000+ mentions
Issue
Eigensoft (RRID:SCR_004965) EIGENSOFT software toolkit, software resource EIGENSOFT package combines functionality from our population genetics methods (Patterson et al. 2006) and our EIGENSTRAT stratification method (Price et al. 2006). The EIGENSTRAT method uses principal components analysis to explicitly model ancestry differences between cases and controls along continuous axes of variation; the resulting correction is specific to a candidate marker''s variation in frequency across ancestral populations, minimizing spurious associations while maximizing power to detect true associations. The EIGENSOFT package has a built-in plotting script and supports multiple file formats and quantitative phenotypes. Source code, documentation and executables for using EIGENSOFT 3.0 on a Linux platform can be downloaded. New features of EIGENSOFT 3.0 include supporting either 32-bit or 64-bit Linux machines, a utility to merge different data sets, a utility to identify related samples (accounting for population structure), and supporting multiple file formats for EIGENSTRAT stratification correction. population genetics, genetics, stratification, variation is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: Harvard Medical School; Massachusetts; USA
PMID:17194218
DOI:10.1038/ng1847
OMICS_07868, nlx_93059 https://sources.debian.org/src/eigensoft/ http://genepath.med.harvard.edu/~reich/Software.htm SCR_004965 EIGENSOFT Software 2026-08-09 09:04:10 1299
Unipro UGENE
 
Resource Report
Resource Website
100+ mentions
Unipro UGENE (RRID:SCR_005579) UGENE software toolkit, software resource A multiplatform open-source software to assist molecular biologists without much expertise in bioinformatics to manage, analyze and visualize their data. UGENE integrates widely used bioinformatics tools within a common user interface. The toolkit supports multiple biological data formats and allows the retrieval of data from remote data sources. It provides visualization modules for biological objects such as annotated genome sequences, Next Generation Sequencing (NGS) assembly data, multiple sequence alignments, phylogenetic trees and 3D structures. Most of the integrated algorithms are tuned for maximum performance by the usage of multithreading and special processor instructions. UGENE includes a visual environment for creating reusable workflows that can be launched on local resources or in a High Performance Computing (HPC) environment. UGENE is written in C++ using the Qt framework. The built-in plugin system and structured UGENE API make it possible to extend the toolkit with new functionality. c++, windows, mac os, linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22368248
DOI:10.1093/bioinformatics/bts091
GNU General Public License, v2, Acknowledgement requested OMICS_01022, biotools:ugene https://bio.tools/ugene, https://sources.debian.org/src/ugene/ SCR_005579 2026-08-09 09:04:08 183
DONE: Detection of Outlier NEurons
 
Resource Report
Resource Website
DONE: Detection of Outlier NEurons (RRID:SCR_005299) DONE software application, software resource Software that performs a morphology-based approach for the automatic identification of outlier neurons based on neuronal tree structures. This tool was used by Zawadzki et al. (2012), who reported on and its application to the NeuroMorpho database. For the analysis, each neuron is represented by a feature vector composed of 20 measurements, which are projected into lower dimensional space with PCA. Bivariate kernel density estimation is then used to obtain a probability distribution for cells. Cells with high probabilities are understood as archetypes, while those with the small probabilities are classified as outliers. Further details about the method and its application in other domains can be found in Costa et al. (2009) and Echtermeyer et al. (2011). This version requires Matlab (Mathworks Inc, Natick, USA) and allows the user to apply the workflow using a graphical user interface. neuron, feature-space, archetype, outlier, matlab, neuromorphometry, computational neuroscience is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: NeuroMorpho.Org
has parent organization: Newcastle University; Newcastle upon Tyne; United Kingdom
FAPESP 05/00587-5;
CNPq 301303/06-1;
CNPq 573583/2008-0;
FAPESP sponsorship 2010/01994-1;
FAPESP sponsorship 2010/16310-0;
EPSRC EP/G03950X/1;
EPSRC EP/E002331/1;
National Research Foundation of Korea R32-10142
PMID:22615032 GNU General Public License nlx_144348 http://www.nitrc.org/projects/done SCR_005299 Detection of Outlier NEurons 2026-08-09 09:04:13 0
Kickstarter
 
Resource Report
Resource Website
10+ mentions
Kickstarter (RRID:SCR_004246) Kickstarter service resource, funding resource Kickstarter is the world''s largest funding platform for creative projects. Every week, tens of thousands of amazing people pledge millions of dollars to projects from the worlds of music, film, art, technology, design, food, publishing and other creative fields. A new form of commerce and patronage. This is not about investment or lending. Project creators keep 100% ownership and control over their work. Instead, they offer products and experiences that are unique to each project. All or nothing funding. On Kickstarter, a project must reach its funding goal before time runs out or no money changes hands. Why? It protects everyone involved. Creators aren''t expected to develop their project without necessary funds, and it allows anyone to test concepts without risk. Each and every project is the independent creation of someone like you. Projects are big and small, serious and whimsical, traditional and experimental. They''re inspiring, entertaining and unbelievably diverse. We hope you agree... Welcome to Kickstarter! nlx_143647 SCR_004246 2026-08-09 09:04:04 19
POPDIST
 
Resource Report
Resource Website
POPDIST (RRID:SCR_004904) POPDIST software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 11, 2023. Software application that calculates a number of different genetic identities, phylogeny reconstructing measures, and distance reconstructing measures (entry from Genetic Analysis Software) gene, genetic, genomic, unix, (aix/irix/decalpha), linux, macos, ms-dos, ms-windows, (95) is listed by: Genetic Analysis Software PMID:21564908 THIS RESOURCE IS NO LONGER IN SERVICE nlx_154542 SCR_004904 2026-08-09 09:04:00 0
ORION Software
 
Resource Report
Resource Website
1+ mentions
ORION Software (RRID:SCR_004389) service resource, software resource ORION is our neuron reconstruction software package developed for the morphological reconstruction of neurons from confocal and multiphoton microscopy data. It accepts raw neuron stack data as input and it is capable of reconstructing the neuron structure, visualizing the output, and exporting the reconstruction in a variety of formats. We are developing tools that will enable Neuroscientists to explore single neuron function via sophisticated image analysis. Advanced optical imaging can produce both structural and functional data and is at the forefront of experimentally exploring the fast, small-scale dynamics of living neurons. Further, compartmental modeling of neuronal function enables rapid testing of hypotheses and estimating experimentally inaccessible parameters. Combining these two techniques will afford unprecedented capabilities in the study of single neuron function. Our software utility bridges the two Neuroscience techniques by rapidly, accurately, and robustly generating, from structural image data, a cylindrical morphology model suitable for simulating neuronal function. has parent organization: University of Houston; Texas; USA University of Houston; Texas; USA ;
NIA RO1-AG027577;
NSF IIS-0431144;
NSF IIS-0638875;
NSF DMS-0915242
nlx_40212 SCR_004389 2026-08-09 09:03:55 1
Yabi
 
Resource Report
Resource Website
Yabi (RRID:SCR_005359) Yabi service resource, software resource A web-based analytical environment framework for bioinformatics applications that can be customized for a diverse range of -omics applications. The software system is adaptable to a range of both pluggable execution and data backends in an open source implementation. Enabling seamless and transparent access to heterogenous HPC environments at its core, it then provides an analysis workflow environment that can create and reuse workflows as well as manage large amounts of both raw and processed data in a secure and flexible way across geographically distributed compute resources. Yabi can be used via a web-based environment to drag-and-drop tools to create sophisticated workflows. It can also be accessed through the Yabi command line which is designed for users that are more comfortable with writing scripts or for enabling external workflow environments to leverage the features in Yabi. Configuring tools can be a significant overhead in workflow environments. Yabi greatly simplifies this task by enabling system administrators to configure as well as manage running tools via a web-based environment and without the need to write or edit software programs or scripts. grid computing, high performance computing, cloud computing, bioinformatics, pipeline, workflow, command line, python, linux, storage, compute, genomics, transcriptomics, proteomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Murdoch University; Perth; Australia
PMID:22333270 GNU General Public License, v3 OMICS_01148, biotools:yabi https://bio.tools/yabi SCR_005359 2026-08-09 09:04:05 0
CATIE - Clinical Antipsychotic Trials in Intervention Effectiveness
 
Resource Report
Resource Website
CATIE - Clinical Antipsychotic Trials in Intervention Effectiveness (RRID:SCR_005615) CATIE, CATIE Schizophrenia, Clinical Antipsychotic Trials in Intervention Effectiveness clinical trial The NIMH-funded Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Study was a nationwide public health-focused clinical trial that compared the effectiveness of older (first available in the 1950s) and newer (available since the 1990s) antipsychotic medications used to treat schizophrenia. These newer medications, known as atypical antipsychotics, cost roughly 10 times as much as the older medications. CATIE is the largest, longest, and most comprehensive independent trial ever done to examine existing therapies for this disease. Schizophrenia is a brain disorder characterized by hallucinations, delusions, and disordered thinking. The course of schizophrenia is variable, but usually is recurrent and chronic, often causing severe disability. Previous studies have shown that taking antipsychotic medications consistently is far more effective than taking no medicine and that the drugs are necessary to manage the disease. The aim of the CATIE study was to determine which medications provide the best treatment for schizophrenia. Additional information may be found by following the links, http://www.nimh.nih.gov/trials/practical/catie/index.shtml, http://www.clinicaltrials.gov/ct/show/NCT00014001?order=1 schizophrenia, clinical trial, treatment, outcome, antipsychotic is used by: Limited Access Datasets From NIMH Clinical Trials
is listed by: ClinicalTrials.gov
is related to: CATIE - Alzheimers Disease
is related to: NIMH Repository and Genomics Resources
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
Schizophrenia NIMH SCR_005512, nlx_146233, nlx_146234 http://www.nimh.nih.gov/health/trials/practical/catie/phase1results.shtml http://www.nimh.nih.gov/health/trials/practical/catie/index.shtml SCR_005615 CATIE Schizophrenia Study, Clinical Antipsychotic Trials in Intervention Effectiveness, Clinical Antipsychotic Trials in Intervention Effectiveness - Schizophrenia 2026-08-09 09:04:16 0
Centre for Neuro Skills
 
Resource Report
Resource Website
Centre for Neuro Skills (RRID:SCR_006106) CNS assessment test provider, material resource A topical portal and providers of brain injury rehabilitation services. Resources * Pharmacology Guide * Glossary of Brain Injury Terms * Brain Injury Research Articles * Common Brain Injury Assessment Tools / Rating Scale * Certified Continuing Education Courses * Links to Resource Sites brain, rehabilitation, therapy Traumatic brain injury, Brain injury nlx_151579 SCR_006106 CNS - Centre for Neuro Skills, Center for Neuro Skills 2026-08-09 09:04:22 0
LDSUPPORT
 
Resource Report
Resource Website
LDSUPPORT (RRID:SCR_007036) software application, software resource Software application (entry from Genetic Analysis Software) gene, genetic, genomic, c, unix, linux is listed by: Genetic Analysis Software nlx_154427 SCR_007036 2026-08-09 09:04:36 0

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