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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
http://www.salk.edu/science/core-facilities/integrative-genomics-and-bioinformatics-core/
Core facility established to assist the Salk community with integrating genomics data into their research. The primary focus of the core is to provide analysis support for next-generation sequencing applications.
Proper citation: Salk Institute Razavi Newman Integrative Genomics and Bioinformatics Core Facility (IGC) (RRID:SCR_014842) Copy
https://www.seattlechildrens.org/research/resources/behavioral-phenotyping-core/
Core dedicated to the protocol driven collection, analysis, and reporting of behavioral data using a blend of classic and innovative assays. Supports neuroscience, psychology, pharmacology, genetics, cancer, and development by providing advanced tools and expertise for the precise measurement and interpretation of behavior.
Proper citation: Seattle Childrens Research Institute Behavioral Phenotyping Core Facility (RRID:SCR_026371) Copy
https://www.bioconductor.org/packages/release/bioc/html/singleCellTK.html
Software R package provides interface to popular tools for importing, quality control, analysis, and visualization of single cell RNA-seq data. Allows users to integrate tools from various packages at different stages of analysis workflow.
Proper citation: singleCellTK (RRID:SCR_026813) Copy
Facility provides training and access to advanced light microscopy systems at an hourly rate. In addition, we are available to consult with and support users at every stage of a project including: experimental design, sample preparation, image acquisition, analysis, and data preparation.
Proper citation: University of Connecticut Advanced Light Microscopy Core Facility (RRID:SCR_027547) Copy
Core facility provides tools for imaging, analysis, environmental testing, and micro/nanofabrication. Offers data, expertise, and hands-on training. From advanced materials to environmental systems, MCFF is the hub where discovery meets precision.
Proper citation: Michigan Technological University Materials Characterization and Fabrication Core Facility (RRID:SCR_027872) Copy
Core specializes in the analysis of small organic and organometallic analytes. Provides access to mass spectrometers for all.
Proper citation: Cornell University Chemistry MS Core Facility (RRID:SCR_028079) Copy
https://www.roswellpark.org/shared-resources/biostatistics-statistical-genomics
Core offers services in design, oversight, implementation, analysis, publication, and reporting of scientific studies including articulating study objectives and hypotheses, grant writing, conceiving appropriate cost-effective designs and models for achievement of study objectives, monitoring interim and final analyses, and co-authoring abstracts and manuscripts.
Proper citation: Roswell Park Comprehensive Cancer Center Biostatistics and Statistical Genomics Shared Resource BSGSR Core Facility (RRID:SCR_028371) Copy
The Centre d''Etude du Polymorphisme Humain (CEPH) is a research laboratory, the main activities of which are the setting up, storage, processing and distribution of DNA collections for the identification of genetic factors conferring susceptibility to complex disorders. These collections are established in partnership and full collaboration with external French or international research groups. The Foundation currently hosts the CEPH reference panel, the HGDP panel (Human genome Diversity Cell Line Panel) and several collections amounting mid-2008 to more than 250 000 samples. The goal of CEPH is to understand complex multifactorial disorders necessitates the establishment of structures facilitating access to large and integrated collection of individuals, characterized by a large number of variables emanating from different technologies and platforms. To achieve this goal, CEPH facilitates the setting up of integrated analyses combining clinical, genetic and environmental data, for the identification of susceptibility factors to complex multifactorial disorders Additionally, CEHP allows the reception, storage, processing and distribution of biological sample collections. At the same time, it promotes and participates in the design and setting up of genetic studies: - in partnership and full collaboration with external research groups - giving access to a large number of variables - in a sufficient number of subjects - allowing large scale integrated analyses
Proper citation: Centre dEtude du Polymorphisme Humain (RRID:SCR_008026) Copy
http://www.imagwiki.nibib.nih.gov/
Special interest group that brings together program officers who have a shared interest in applying modeling and analysis methods to biomedical systems. The meetings are formatted to facilitate an open discussion of what is currently being supported, and for planning future directions in these areas. At each meeting, time is allotted to hear focused presentations from one or two participants to discuss issues relating to modeling and analysis across the government agencies. Discussions also occur online, and participants are informed of talks, conferences and other activities of interest to the group. IMAG recognized that the modeling community is on the forefront of thinking across the biological continuum, rather than just focusing at one scale or level of resolution. In addition IMAG identified a strong desire among modelers to form multi-disciplinary partnerships across varied research communities. Overall Intent of IMAG through the MSM Consortium is: * To develop new methodologies that span across biological scales * To develop multiscale methodologies applicable to biomedical, biological and behavioral research * To develop methodologies within the local multidisciplinary team and within the larger Framework environment * To further promote multiscale modeling through model sharing This wiki contains information relevant to the IMAG (Interagency Modeling and Analysis Group) and the MSM (Multi-scale Modeling Consortium).
Proper citation: Interagency Modeling and Analysis Group and Multi-scale Modeling Consortium Wiki (RRID:SCR_008046) Copy
http://wiki.c2b2.columbia.edu/honiglab_public/index.php/Software:Jackal
Jackal is a collection of programs designed for the modeling and analysis of protein structures. Its core program is a versatile homology modeling package. It contains twelve individual programs, each with their own function.
Proper citation: Jackal (RRID:SCR_008665) Copy
Ratings or validation data are available for this resource
http://www.ingenuity.com/products/pathways_analysis.html
A web-based software application that enables users to analyze, integrate, and understand data derived from gene expression, microRNA, and SNP microarrays, metabolomics, proteomics, and RNA-Seq experiments, and small-scale experiments that generate gene and chemical lists. Users can search for targeted information on genes, proteins, chemicals, and drugs, and build interactive models of experimental systems. IPA allows exploration of molecular, chemical, gene, protein and miRNA interactions, creation of custom molecular pathways, and the ability to view and modify metabolic, signaling, and toxicological canonical pathways. In addition to the networks and pathways that can be created, IPA can provide multiple layering of additional information, such as drugs, disease genes, expression data, cellular functions and processes, or a researchers own genes or chemicals of interest.
Proper citation: Ingenuity Pathway Analysis (RRID:SCR_008653) Copy
https://www.nature.com/articles/s41467-018-03367-w
Nanodroplet processing platform for deep and quantitative proteome profiling of 10 to 100 mammalian cells. It enhances efficiency and recovery of sample processing by downscaling processing volumes.
Proper citation: nanoPOTS (RRID:SCR_017129) Copy
Manufacturer located in Palo Alto, California, USA, that has made developments in fields of radiotherapy, radiosurgery, X-ray tube technology, digital image detectors, cargo screening, and non-destructive testing. Varian technology and software for processing diagnostic X-ray images is being used in radiotherapy and analysis.
Proper citation: Varian Medical Systems, Inc. (RRID:SCR_017372) Copy
http://www.informatics.jax.org/batch_data.shtml
Software tool to access various mouse genome information in batch format. Batch data and analysis tools.
Proper citation: Batch Data and Analysis Tool (RRID:SCR_017515) Copy
https://www.bio-rad.com/en-us/product/bio-plex-200-systems?ID=715b85f1-6a4e-41b3-b5d9-80202d779e13
Suspension array system which offers protein and nucleic acid researchers multiplex assay solution permiting analysis of up to 100 biomolecules in single sample.
Proper citation: Bio-Rad: Bio-Plex 200 System (RRID:SCR_018026) Copy
https://pedsresearch.org/uploads/pages/img/LuminexManual_LX100.pdf
Flow cytometry analyzer system for individual labs that performs up to 100 different tests in single reaction volume and can use either magnetic beads or plain polystyrene beads.
Proper citation: Luminex: 100 Flow Cytometry Analyzer System (RRID:SCR_018025) Copy
http://www.genboree.org/java-bin/EpigenomeAtlas/workbench.jsp?isPublic=yes&context=EpigenomeAtlas
Service where users are able to upload and store data, access bioinformatics tools, and perform analyses.
Proper citation: Genboree Workbench (RRID:SCR_011864) Copy
http://www.compudrug.com/metabolexpert
Software tool for initial estimation of the structural formula of metabolites, which might be formed by a substance in humans, animals or in plants. MetabolExpert is also capable of predicting the most common metabolic pathways in animals, exporting results to SDF and RDF format and graphical highlighting that empasizes the essence of metabolic reactions that occurred.
Proper citation: MetabolExpert (RRID:SCR_014908) Copy
Commercial developer of database and predictive model software tools used in chemical toxicity assessment.
Proper citation: Leadscope (RRID:SCR_014904) Copy
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