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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://pctriadd.com/genomic-analysis/overview
Core offers sequencing and microarray services, solutions for the profiling of FFPE tissues, and complete, project-tailored downstream bioinformatics analysis. The core's structure enables the management of research projects from experimental design to analysis and interpretation of data as well as support for grant applications and publications. The LAGA provides open fee-for-service access as a core facility (intra-institutional services to its researchers) and as regional, national and international facility (inter-institutional services).
Proper citation: Vancouver Prostate Centre Laboratory for Advanced Genome Analysis (RRID:SCR_012394) Copy
https://systemsbiology.columbia.edu/genome-center
Core sells sequencing data and bioinformatic analytics services to the scientific community. Core aims to permit the development of research on sequencing protocols and encourage collaboration with clinicians to develop the next generation genomic DNA testing.
Proper citation: JP Sulzberger Columbia Genome Center (RRID:SCR_012650) Copy
http://www.sbpdiscovery.org/technology/sr/Pages/LaJolla_Cheminformatics.aspx
Core facility that supports assay development, high throughput (HTS), ultra-high throughput (uHTS), and high-content screening (HCS) activities performed at the Conrad Prebys Center for Chemical Genomics by providing databases and tools for compound registration and inventory, HTS plate formatting and tracking, HTS and HCS bioassay data processing as well as related data and information handling. Data mining and reporting are also facilitated with a user-friendly database interface. The Cheminformatics core also supports the design and obtaining of appropriate compound collections, as well as SAR follow-up of hits, hit-to-lead optimization and in silico screening through docking and other molecular modeling approaches.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cheminformatics Core (RRID:SCR_014875) Copy
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
http://www.salk.edu/science/core-facilities/integrative-genomics-and-bioinformatics-core/
Core facility established to assist the Salk community with integrating genomics data into their research. The primary focus of the core is to provide analysis support for next-generation sequencing applications.
Proper citation: Salk Institute Razavi Newman Integrative Genomics and Bioinformatics Core Facility (IGC) (RRID:SCR_014842) Copy
http://chicagodiabetesresearch.org/cores/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 30,2023. Core facility that provides analytic support for a wide range of projects in diabetes translation research ranging from program evaluation to cost-effectiveness analysis.
Proper citation: Chicago Center for Diabetes Translation Research Quantitative Analysis Core (RRID:SCR_015208) Copy
http://depts.washington.edu/cfrtc/genomics/
Core provides genomics-based tools, data management and analysis tools, and creates platforms that integrate data from the Clinical and Immunology Cores for human samples and bacterial isolates. Services include consultation and experimental design assistance for using new-generation sequencing technology, data analysis, bioinformatic support, data access and storage, high throughput and new-generation whole-genome sequencing, and RNA-seq analysis of transcriptomes.
Proper citation: University of Washington Genomics Core Cystic Fibrosis Research Translation Center and Research Development Program (RRID:SCR_015404) Copy
http://digestivediseasescenters.org/content/ddrc-emory-university-overview
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 5th,2023. Core facility for the Emory Epithelial Pathobiology Research Development Center.
Proper citation: Emory Epithelial Pathobiology Research Development Center Image Analysis Core (RRID:SCR_015909) Copy
The Centre d''Etude du Polymorphisme Humain (CEPH) is a research laboratory, the main activities of which are the setting up, storage, processing and distribution of DNA collections for the identification of genetic factors conferring susceptibility to complex disorders. These collections are established in partnership and full collaboration with external French or international research groups. The Foundation currently hosts the CEPH reference panel, the HGDP panel (Human genome Diversity Cell Line Panel) and several collections amounting mid-2008 to more than 250 000 samples. The goal of CEPH is to understand complex multifactorial disorders necessitates the establishment of structures facilitating access to large and integrated collection of individuals, characterized by a large number of variables emanating from different technologies and platforms. To achieve this goal, CEPH facilitates the setting up of integrated analyses combining clinical, genetic and environmental data, for the identification of susceptibility factors to complex multifactorial disorders Additionally, CEHP allows the reception, storage, processing and distribution of biological sample collections. At the same time, it promotes and participates in the design and setting up of genetic studies: - in partnership and full collaboration with external research groups - giving access to a large number of variables - in a sufficient number of subjects - allowing large scale integrated analyses
Proper citation: Centre dEtude du Polymorphisme Humain (RRID:SCR_008026) Copy
http://www.imagwiki.nibib.nih.gov/
Special interest group that brings together program officers who have a shared interest in applying modeling and analysis methods to biomedical systems. The meetings are formatted to facilitate an open discussion of what is currently being supported, and for planning future directions in these areas. At each meeting, time is allotted to hear focused presentations from one or two participants to discuss issues relating to modeling and analysis across the government agencies. Discussions also occur online, and participants are informed of talks, conferences and other activities of interest to the group. IMAG recognized that the modeling community is on the forefront of thinking across the biological continuum, rather than just focusing at one scale or level of resolution. In addition IMAG identified a strong desire among modelers to form multi-disciplinary partnerships across varied research communities. Overall Intent of IMAG through the MSM Consortium is: * To develop new methodologies that span across biological scales * To develop multiscale methodologies applicable to biomedical, biological and behavioral research * To develop methodologies within the local multidisciplinary team and within the larger Framework environment * To further promote multiscale modeling through model sharing This wiki contains information relevant to the IMAG (Interagency Modeling and Analysis Group) and the MSM (Multi-scale Modeling Consortium).
Proper citation: Interagency Modeling and Analysis Group and Multi-scale Modeling Consortium Wiki (RRID:SCR_008046) Copy
http://wiki.c2b2.columbia.edu/honiglab_public/index.php/Software:Jackal
Jackal is a collection of programs designed for the modeling and analysis of protein structures. Its core program is a versatile homology modeling package. It contains twelve individual programs, each with their own function.
Proper citation: Jackal (RRID:SCR_008665) Copy
Ratings or validation data are available for this resource
http://www.ingenuity.com/products/pathways_analysis.html
A web-based software application that enables users to analyze, integrate, and understand data derived from gene expression, microRNA, and SNP microarrays, metabolomics, proteomics, and RNA-Seq experiments, and small-scale experiments that generate gene and chemical lists. Users can search for targeted information on genes, proteins, chemicals, and drugs, and build interactive models of experimental systems. IPA allows exploration of molecular, chemical, gene, protein and miRNA interactions, creation of custom molecular pathways, and the ability to view and modify metabolic, signaling, and toxicological canonical pathways. In addition to the networks and pathways that can be created, IPA can provide multiple layering of additional information, such as drugs, disease genes, expression data, cellular functions and processes, or a researchers own genes or chemicals of interest.
Proper citation: Ingenuity Pathway Analysis (RRID:SCR_008653) Copy
https://www.nature.com/articles/s41467-018-03367-w
Nanodroplet processing platform for deep and quantitative proteome profiling of 10 to 100 mammalian cells. It enhances efficiency and recovery of sample processing by downscaling processing volumes.
Proper citation: nanoPOTS (RRID:SCR_017129) Copy
Manufacturer located in Palo Alto, California, USA, that has made developments in fields of radiotherapy, radiosurgery, X-ray tube technology, digital image detectors, cargo screening, and non-destructive testing. Varian technology and software for processing diagnostic X-ray images is being used in radiotherapy and analysis.
Proper citation: Varian Medical Systems, Inc. (RRID:SCR_017372) Copy
http://www.informatics.jax.org/batch_data.shtml
Software tool to access various mouse genome information in batch format. Batch data and analysis tools.
Proper citation: Batch Data and Analysis Tool (RRID:SCR_017515) Copy
https://www.bio-rad.com/en-us/product/bio-plex-200-systems?ID=715b85f1-6a4e-41b3-b5d9-80202d779e13
Suspension array system which offers protein and nucleic acid researchers multiplex assay solution permiting analysis of up to 100 biomolecules in single sample.
Proper citation: Bio-Rad: Bio-Plex 200 System (RRID:SCR_018026) Copy
https://pedsresearch.org/uploads/pages/img/LuminexManual_LX100.pdf
Flow cytometry analyzer system for individual labs that performs up to 100 different tests in single reaction volume and can use either magnetic beads or plain polystyrene beads.
Proper citation: Luminex: 100 Flow Cytometry Analyzer System (RRID:SCR_018025) Copy
http://www.genboree.org/java-bin/EpigenomeAtlas/workbench.jsp?isPublic=yes&context=EpigenomeAtlas
Service where users are able to upload and store data, access bioinformatics tools, and perform analyses.
Proper citation: Genboree Workbench (RRID:SCR_011864) Copy
http://www.compudrug.com/metabolexpert
Software tool for initial estimation of the structural formula of metabolites, which might be formed by a substance in humans, animals or in plants. MetabolExpert is also capable of predicting the most common metabolic pathways in animals, exporting results to SDF and RDF format and graphical highlighting that empasizes the essence of metabolic reactions that occurred.
Proper citation: MetabolExpert (RRID:SCR_014908) Copy
Commercial developer of database and predictive model software tools used in chemical toxicity assessment.
Proper citation: Leadscope (RRID:SCR_014904) Copy
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