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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Ribosomal Database Project
 
Resource Report
Resource Website
1000+ mentions
Ribosomal Database Project (RRID:SCR_006633) RDP data or information resource, database, resource A database which provides ribosome related data services to the scientific community, including online data analysis, rRNA derived phylogenetic trees, and aligned and annotated rRNA sequences. It specifically contains information on quality-controlled, aligned and annotated bacterial and archaean 16S rRNA sequences, fungal 28S rRNA sequences, and a suite of analysis tools for the scientific community. Most of the RDP tools are now available as open source packages for users to incorporate in their local workflow. microbiome, database, rrna gene sequence, rrna, ribosome, genome browser, high-throughput sequencing, bacteria, archaea, fungi, FASEB list is listed by: OMICtools
is listed by: Human Microbiome Project
has parent organization: Michigan State University; Michigan; USA
is parent organization of: RDPipeline
DOE DE-FG02-99ER62848;
DOE DE-SC0004601;
DOE DE-FC02-07ER64494;
NIEHS P42 ES004911;
NSF DBI-0328255;
USDA 2008-35107-04542;
NHLBI U01HL098961;
NIDDK UH3 DK083993
PMID:24288368
PMID:17586664
Open source r3d100012372, nif-0000-03404, OMICS_01513 https://doi.org/10.17616/R3C087 SCR_006633 Ribosomal Database Project 2026-09-19 12:51:15 1724
Ontology Lookup Service
 
Resource Report
Resource Website
10+ mentions
Ontology Lookup Service (RRID:SCR_006596) OLS data access protocol, data or information resource, database, software resource, source code, web service Interactive and programmatic interfaces to query, browse and navigate an increasing number of biomedical ontologies and controlled vocabularies. It provides a web service interface to query multiple ontologies from a single location with a unified output format. It can integrate any ontology available in the Open Biomedical Ontology (OBO) format. The database can be queried to obtain information on a single term or to browse a complete ontology using AJAX. Auto-completion provides a user-friendly search mechanism. An AJAX-based ontology viewer is available to browse a complete ontology or subsets of it. A weekly MySQL database export file can be downloaded from the EBI public FTP directory. ontology, ontology or annotation browser, ontology or annotation search engine, gold standard lists: Cell Type Ontology
is listed by: Gene Ontology Tools
is listed by: OMICtools
is related to: Gene Ontology
is related to: OBO-Edit
is related to: OBO
has parent organization: European Bioinformatics Institute
BBSRC ;
iSPIDER ;
European Union FP6 Felics contract 021902 (RII3)
PMID:18467421
PMID:16507094
Apache License, v2, Acknowledgement requested OMICS_02275, nif-0000-10390, r3d100010413 https://doi.org/10.17616/R3GS9G http://www.ebi.ac.uk/ols SCR_006596 OLS - Ontology Lookup Service, Ontology Lookup Service (OLS) 2026-09-19 12:51:14 24
ALEXA-Seq
 
Resource Report
Resource Website
1+ mentions
ALEXA-Seq (RRID:SCR_006700) ALEXA-Seq software resource A method for using massively parallel paired-end transcriptome sequencing for ''alternative expression analysis''. is listed by: OMICtools OMICS_01328 SCR_006700 2026-09-19 12:51:16 6
Rice Genome Annotation
 
Resource Report
Resource Website
1000+ mentions
Rice Genome Annotation (RRID:SCR_006663) Osa1 analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Database and resource that provides sequence and annotation data for the rice genome. This website provides genome sequence from the Nipponbare subspecies of rice and annotation of the 12 rice chromosomes. All structural and functional annotation is viewable through our Rice Genome Browser which currently supports 75 tracks of annotation. Enhanced data access is available through web interfaces, FTP downloads and a Data Extractor tool developed in order to support discrete dataset downloads. Rice is a model species for the monocotyledonous plants and the cereals which are the greatest source of food for the world''s population. While rice genome sequence is available through multiple sequencing projects, high quality, uniform annotation is required in order for genome sequence data to be fully utilized by researchers. The existence of a common gene set and uniform annotation allows researchers within the rice community to work from a common resource so that their results can be more easily interpreted by other scientists. The objective of this project has always been to provide high quality annotation for the rice genome. They generated, refined and updated gene models for the estimated 40,000-60,000 total rice genes, provided standardized annotation for each model, linked each model to functional annotation including expression data, gene ontologies, and tagged lines. They have provided a resource to extend the annotation of the rice genome to other plant species by providing comparative alignments to other plant species. Analysis/Tools are available including: BLAST, Locus Name Search, Functional Term Search, Protein Domain Search, Anatomy Expression Viewer, Highly Expressed Genes rice, oryza sativa, maize, corn, zea mays, wheat, triticum aestivum, gene, genome, annotation, FASEB list is listed by: OMICtools
has parent organization: Michigan State University; Michigan; USA
NSF DBI-0321538;
NSF DBI-0834043
PMID:17145706 Acknowledgement requested OMICS_01563, nif-0000-31459 http://rice.tigr.org http://rice.plantbiology.msu.edu/pseudomolecules/info.shtml SCR_006663 Rice Genome Annotation Project, MSU Rice Genome Annotation Project Database and Resource 2026-09-19 12:51:15 1600
qSNP
 
Resource Report
Resource Website
10+ mentions
qSNP (RRID:SCR_005105) qSNP software resource A single nucleotide variant caller optimised for identifying somatic variants in low cellularity cancer samples. is listed by: OMICtools
has parent organization: University of Queensland; Brisbane; Australia
Cancer PMID:24250782 OMICS_00089 SCR_005105 2026-09-19 12:50:47 26
SAMtools/BCFtools
 
Resource Report
Resource Website
1000+ mentions
SAMtools/BCFtools (RRID:SCR_005227) BCFtools software resource Provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format. snp, indel, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SAMTOOLS
DOI:10.1101/090811 biotools:bcftools, OMICS_13458 https://bio.tools/bcftools, https://sources.debian.org/src/bcftools/ SCR_005227 2026-09-19 12:50:49 1066
MiTie
 
Resource Report
Resource Website
1+ mentions
MiTie (RRID:SCR_005228) MiTie software resource Software framework for simultaneous RNA-Seq-based Transcript Identification and Quantification in Multiple Samples. They define a likelihood function based on the negative binomial distribution, use a regularization approach to select a few transcripts collectively explaining the observed read data, and show how to find the optimal solution using Mixed Integer Programming. MiTie can a) take advantage of known transcripts, b) reconstruct and quantify transcripts simultaneously in multiple samples, as well as c) resolve the location of multi-mapping reads. It is designed for genome- and assembly-based transcriptome reconstruction. c++, rna-seq, transcript is listed by: OMICtools OMICS_01279 SCR_005228 MiTie: Simultaneous RNA-Seq-based Transcript Identification and Quantification in Multiple Samples 2026-09-19 12:50:49 4
ORMAN
 
Resource Report
Resource Website
1+ mentions
ORMAN (RRID:SCR_005188) ORMAN software resource A software tool for resolving multi-mappings within an RNA-Seq SAM file. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24130305 OMICS_01284, biotools:orman https://bio.tools/orman SCR_005188 ORMAN : Optimal Resolution of Ambiguous RNA-Seq Multi-mappings in the Presence of Novel Isoforms 2026-09-19 12:50:49 4
FRCbam
 
Resource Report
Resource Website
10+ mentions
FRCbam (RRID:SCR_005189) software resource Software package containing tools to process bam files in order to evaluate and analyze de novo assembly / assemblers and identify Structural Variations suspicious genomics regions. The tools have been already successfully applied in several de novo and resequencing projects. This package contains two tools: # FRCbam: tool to compute Feature Response Curves in order to validate and rank assemblies and assemblers # FindTranslocations: tool to identify chromosomal rearrangements using Mate Pairs standalone software, sam, bam is listed by: OMICtools PMID:23284938 GNU General Public License, v3 OMICS_04070 SCR_005189 2026-09-19 12:50:49 11
SeqAnt
 
Resource Report
Resource Website
1+ mentions
SeqAnt (RRID:SCR_005186) SeqAnt analysis service resource, data analysis service, production service resource, service resource, software resource A free web service and open source software package that performs rapid, automated annotation of DNA sequence variants (single base mutations, insertions, deletions) discovered with any sequencing platform. Variant sites are characterized with respect to their functional type (Silent, Replacement, 5' UTR, 3' UTR, Intronic, Intergenic), whether they have been previously submitted to dbSNP, and their evolutionary conservation. Annotated variants can be viewed directly on the web browser, downloaded in a tab delimited text file, or directly uploaded in a Browser Extended Data (BED) format to the UCSC genome browser. SeqAnt further identifies all loci harboring two or more coding sequence variants that help investigators identify potential compound heterozygous loci within exome sequencing experiments. In total, SeqAnt resolves a significant bottleneck by allowing an investigator to rapidly prioritize the functional analysis of those variants of interest. annotation, dna sequence variant, single base mutation, insertion, deletion, sequencing, mutation, variant, sequence variant, perl, sequence, genome is listed by: OMICtools
has parent organization: Emory University; Georgia; USA
has parent organization: SourceForge
PMID:20854673 GNU General Public License, v2 OMICS_00182 SCR_005186 SeqAnt - Sequence Annotator 2026-09-19 12:50:49 2
NGS-SNP
 
Resource Report
Resource Website
10+ mentions
NGS-SNP (RRID:SCR_005182) NGS-SNP software resource A collection of command-line scripts for providing rich annotations for SNPs identified by the sequencing of transcripts or whole genomes from organisms with reference sequences in Ensembl. Included among the annotations, several of which are not available from any existing SNP annotation tools, are the results of detailed comparisons with orthologous sequences. These comparisons allow, for example, SNPs to be sorted or filtered based on how drastically the SNP changes the score of a protein alignment. Other fields indicate the names of overlapping protein domains or features, and the conservation of both the SNP site and flanking regions. NCBI, Ensembl, and Uniprot IDs are provided for genes, transcripts, and proteins when applicable, along with Gene Ontology terms, a gene description, phenotypes linked to the gene, and an indication of whether the SNP is novel or known. A ?Model_Annotations? field provides several annotations obtained by transferring in silico the SNP to an orthologous gene, typically in a well-characterized species. annotation, snp, sequencing, transcript, genome, reference sequence, indel, annotate, reference chromosome, reference transcript, gene, command-line is listed by: OMICtools
is related to: Ensembl
has parent organization: University of Alberta; Alberta; Canada
OMICS_00177 SCR_005182 2026-09-19 12:50:49 33
Indelocator
 
Resource Report
Resource Website
10+ mentions
Indelocator (RRID:SCR_005258) Indelocator software resource A software tool for calling short indels in next generation sequencing data. is listed by: OMICtools
has parent organization: Broad Institute
OMICS_00098 SCR_005258 2026-09-19 12:50:50 45
GASVPro
 
Resource Report
Resource Website
1+ mentions
GASVPro (RRID:SCR_005259) GASVPro data analysis software, data processing software, sequence analysis software, software application, software resource Software tool combining both paired read and read depth signals into probabilistic model which can analyze multiple alignments of reads. Used to find structural variation in both normal and cancer genomes using data from variety of next-generation sequencing platforms. Used to predict structural variants directly from aligned reads in SAM/BAM format.Combines read depth information along with discordant paired read mappings into single probabilistic model two common signals of structural variation. When multiple alignments of read are given, GASVPro utilizes Markov Chain Monte Carlo procedure to sample over the space of possible alignments. structural variation, genome, genomics, alignment, sequencing, variant, variation, detection, dna, paired, end, read, sequence is listed by: OMICtools
is related to: GASV
has parent organization: Brown University; Rhode Island; USA
Burroughs Wellcome Career Award at the Scientific Interface ;
NHGRI R01 HG5690
PMID:22452995 Free, Available for download, Freely available OMICS_00317 http://code.google.com/p/gasv/downloads/list SCR_005259 GASVPro: Geometric Analysis of Structural Variants 2026-09-19 12:50:50 8
PRISM (Stanford database)
 
Resource Report
Resource Website
10000+ mentions
PRISM (Stanford database) (RRID:SCR_005375) PRISM analysis service resource, data analysis service, data or information resource, database, production service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5,2022.Tool that predicts interactions between transcription factors and their regulated genes from binding motifs. Understanding vertebrate development requires unraveling the cis-regulatory architecture of gene regulation. PRISM provides accurate genome-wide computational predictions of transcription factor binding sites for the human and mouse genomes, and integrates the predictions with GREAT to provide functional biological context. Together, accurate computational binding site prediction and GREAT produce for each transcription factor: 1. putative binding sites, 2. putative target genes, 3. putative biological roles of the transcription factor, and 4. putative cis-regulatory elements through which the factor regulates each target in each functional role., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. genomic, transcription factor, function, transcription factor binding site, transcription factor regulator, biological role, target gene, target genomic region, genome, FASEB list is listed by: OMICtools
is listed by: SoftCite
is related to: GREAT: Genomic Regions Enrichment of Annotations Tool
has parent organization: Stanford University School of Medicine; California; USA
PMID:23382538 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00489 SCR_005375 Predicting Regulatory Information from Single Motifs 2026-09-19 12:50:52 40822
Knime4Bio
 
Resource Report
Resource Website
1+ mentions
Knime4Bio (RRID:SCR_005376) Knime4Bio software resource A set of custom nodes for the KNIME (The Konstanz Information Miner) graphical workbench, for analysing next-generation sequencing (NGS) data without the requirement of programming skills. node, next-generation sequencing, knime, bioinformatics, workflow, sequencing, flow, data, bam, wig, bed, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:21984761 GNU General Public License, v3 biotools:knime4bio, OMICS_01143 https://bio.tools/knime4bio SCR_005376 Knime4Bio: custom nodes for the interpretation of Next Generation Sequencing data with KNIME 2026-09-19 12:50:52 2
Ergatis
 
Resource Report
Resource Website
1+ mentions
Ergatis (RRID:SCR_005377) Ergatis software resource A web interface and scalable software system for bioinformatics workflows that is used to create, run, and monitor reusable computational analysis pipelines. It contains pre-built components for common bioinformatics analysis tasks. These components can be arranged graphically to form highly-configurable pipelines. Each analysis component supports multiple output formats, including the Bioinformatic Sequence Markup Language (BSML). The current implementation includes support for data loading into project databases following the CHADO schema, a highly normalized, community-supported schema for storage of biological annotation data. Ergatis uses the Workflow engine to process its work on a compute grid. Workflow provides an XML language and processing engine for specifying the steps of a computational pipeline. It provides detailed execution status and logging for process auditing, facilitates error recovery from point of failure, and is highly scalable with support for distributed computing environments. The XML format employed enables commands to be run serially, in parallel, and in any combination or nesting level. workflow, bioinformatics, workflow management, pipeline, computation, genomics, genome, processing is listed by: OMICtools
has parent organization: SourceForge
has parent organization: University of Maryland School of Medicine; Maryland; USA
PMID:20413634 Artistic License OMICS_01140 SCR_005377 ergatis: workflow creation and monitoring interface 2026-09-19 12:50:52 2
PAZAR
 
Resource Report
Resource Website
10+ mentions
PAZAR (RRID:SCR_005410) PAZAR data or information resource, data repository, database, service resource, software resource, storage service resource Database that unites independently created and maintained data collections of transcription factor and regulatory sequence annotation. The flexible PAZAR schema permits the representation of diverse information derived from experiments ranging from biochemical protein-DNA binding to cellular reporter gene assays. Data collections can be made available to the public, or restricted to specific system users. The data ''boutiques'' within the shopping-mall-inspired system facilitate the analysis of genomics data and the creation of predictive models of gene regulation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor, target gene, regulatory sequence, transcription factor profile, annotation, sequence, profile, transcription factor binding profile, chip, chip-seq, gene, cis-regulatory element, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of British Columbia; British Columbia; Canada
has parent organization: SourceForge
PMID:18971253 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00540, biotools:pazar https://bio.tools/pazar SCR_005410 2026-09-19 12:50:53 32
CREST
 
Resource Report
Resource Website
50+ mentions
CREST (RRID:SCR_005257) CREST software resource An algorithm for detecting genomic structural variations at base-pair resolution using next-generation sequencing data. CREST uses pieces of DNA called soft clips to find structural variations. Soft clips are the DNA segments produced during sequencing that fail to properly align to the reference genome as the sample genome is reassembled. CREST uses the soft clips to precisely identify sites of chromosomal rearrangement or where pieces of DNA are inserted or deleted. genome, structural variation, next-generation sequencing, soft clip is listed by: OMICtools
has parent organization: Pennsylvania State University
PMID:21666668 OMICS_00312 SCR_005257 2026-09-19 12:50:50 57
MolBioLib
 
Resource Report
Resource Website
MolBioLib (RRID:SCR_005372) MolBioLib software resource A compact, portable, and extensively tested C++11 software framework and set of applications tailored to the demands of next-generation sequencing data and applicable to many other applications. It is designed to work with common file formats and data types used both in genomic analysis and general data analysis. A central relational-database-like Table class is a flexible and powerful object to intuitively represent and work with a wide variety of tabular datasets, ranging from alignment data to annotations. MolBioLib includes programs to perform a wide variety of analysis tasks such as computing read coverage, annotating genomic intervals, and novel peak calling with a wavelet algorithm. This package assumes fluency in both UNIX and C++. c++, next-generation sequencing, genomic, analysis, genome is listed by: OMICtools
has parent organization: SourceForge
PMID:22815363 OMICS_01145 SCR_005372 MolBioLib: C++11 framework for rapid develop and deploy of bioinformatic tasks 2026-09-19 12:50:52 0
pyDNase
 
Resource Report
Resource Website
10+ mentions
pyDNase (RRID:SCR_005406) pyDNase software resource A software library for analyzing DNase-seq data. is listed by: OMICtools OMICS_00518 SCR_005406 2026-09-19 12:50:53 43

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