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https://www.ohsu.edu/flow-cytometry-core

Core facility that provides the following services: Analytical flow cytometry service, Cell sorting service, Flow cytometry data analysis service, Grant preparation support service, Flow cytometry instrument training, Flow cytometry consultation service. The OHSU Flow Cytometry Shared Resource (FCSR) has operated as a core resource for OHSU Knight Cancer Institute members since 1996 and provides advanced flow cytometry instrumentation, technical expertise and technical services. The FCSR also provides training in data interpretation, experiment design and routine operation to researchers, offering an additional cost-saving option of doing some of the work themselves. Finally, this resource saves valuable investigator time by analyzing specimens and preparing them, if needed.

Proper citation: OHSU Flow Cytometry and Monoclonal Antibody Shared Resource Core Facility (RRID:SCR_009974) Copy   

•   Source: SciCrunch Registry

http://ohsu.eagle-i.net/i/0000013c-e05d-718e-6d01-360380000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 6,2022. Core facility provides the following services: Data Management Consultation, Research Databases: REDCap & Customized Databases, Functional Genomics Consultation: Microarray Proteomics. The Biomedical Informatics Program (BMIP) provides investigators with informatics tools and methodologies to support translational researchers. Using a hybrid of collaborative and service approaches, BMIP is continually developing and deploying an array of informatics tools for bench research (bioinformatics), bedside research (clinical research informatics), and translation to practice (medical informatics). BMIP also provides a platform for collaborative and multidisciplinary informatics education and research. The Biomedical Informatics Program includes two major areas of emphasis: Translational Bioinformatics - Novel methodology development, Statistical Genetics, Functional Genomics, Clinical Research Informatics, Research Data Warehouse - Using Epic and other clinical data for research, Clinical research data management software, Epic as an interventional tool for research

Proper citation: Oregon Clinical and Translational Research Institute Biomedical Informatics Program (RRID:SCR_009965) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/pharmacokinetics-core

Core for analysis of drugs and their metabolites and bio-molecules such as simple peptides, oligonucleotides, carbohydrates, lipids, fatty acids and steroids. Provides open access to laboratory where users prepare and analyze their own samples by HPLC, GC/MS or LC/MS on equipment maintained by core personnel. Provides analysis of samples including development of analytical methods, sample preparation, and data analysis for clinical trials as well as basic science investigations.

Proper citation: OHSU Bioanalytical Shared Resource Pharmacokinetics Core Facility (RRID:SCR_009963) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/advanced-imaging-research-center/about-advanced-imaging-research-center

Provides magnetic resonance instruments including Siemens 3 Tesla Prisma, Siemens Magnetom 7 Tesla, and Bruker 11.75 Tesla to support research investigating normal physiology, brain development and aging, and disease pathophysiology with high performance non invasive imaging capabilities.

Proper citation: OHSU Advanced Imaging Research Center Core Facility (RRID:SCR_009960) Copy   

•   Source: SciCrunch Registry

https://www.ohsu.edu/proteomics-shared-resource

Core facility that provides the following services: Protein identification and partial sequencing, Determination of whole protein mass, Targeted SRM analysis of known proteins, Protein quantitation assay, Gel electrophoresis. The OHSU Protemics Shared Resource facility was established to make state-of-the-art mass spectrometry based protein analysis analytical capabilities available to the biomedical research community at OHSU.

Proper citation: OHSU Proteomics Shared Resource Core Facility (RRID:SCR_009991) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7ce8-c10b-fbab-3b8480000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1,2023. Core facility that provides the following services: Flow cytometry analysis service, Cell sorting and analysis service, Flow cytometer analyzer access, Introductory flow cytometry training, Advanced and customized flow cytometry training, Flow cytometry consultation service, FACSAria training, Flow cytometry data analysis, BSL2+ biohazardous human cell sorting, BSL2+ murine biohazardous cell sorting, BSL2+ murine cell sorting access, Non-infectious cell sorting access. The Flow Cytometry and Cell Sorting Resource Laboratory is currently recognized as one of the largest and most comprehensive flow cytometry laboratories in the US. In 2010 it was designated a laboratory of exceptional merit by the National Cancer Institute. Using state-of-the-art technology, the resource provides a broad array of, instrumentation, support, education and consultation to the research community at the University of Pennsylvania. A wide variety of cell sorting applications are supported, from high-speed multicolor (up to 14 colors) cell sorting to low-speed, large nozzle, improved viability sorting. Additionally, a wide variety of cell analysis services (up to 20 parameters) are offered, from traditional analog, easier to use tabletop analyzers to many-laser, many-color, high-speed, fully-digital modern instrumentation. Currently the facility offers 6 cell sorters and 19 analytical instruments. A very active training and consultation program is in place to support these activities. The Scientific Director, Dr. Jonni Moore, and the Technical Director, each have over 25 years experience in the field of cytomics. Researchers at the University of Pennsylvania are increasingly engaged in research projects that require 8-plus-parameter cell sorting of infectious cells and primary human tissues. Investigators using the Flow Cytometry and Cell Sorting Shared Resource have access to virtually any type of cytometric services required for a vast array of applications.

Proper citation: Penn Flow Cytometry and Cell Sorting Resource Laboratory (RRID:SCR_010011) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-9652-3f24-55da-381e80000000

Core facility that provides the following services: Double- and triple-labeling experiments, Acquisition of high-resolution images: 2048 x 2048 pixels, Single molecule visualization, allowing dynamic observation and functional analyses of both in vivo and living cells, Total internal reflection fluorescence experiments (TIRF).

This Core consists of a Zeiss LSM 5 Pascal laser confocal microscope with a Zeiss RGB vario laser module and Nikon C1 Confocal/TIRF System with 3 PMT. A Zeiss Axiovert 200 fully motorized light microscope is available with fluorescence, bright-field, phase-contrast and Nomarski (DIC) capabilities. Image acquisition and analyses are performed using Zeiss LSM 5 Pascal Confocal Microscopy Software (Release 3.2) on 2 workstations. Zeiss Physiology software is available also. Live cell imaging is available using a Zeiss temperature controller with custom chamber and heating stage. The Nikon C1 Confocal/TIRF System fully motorized Nikon Eclipse Ti microscope is available with fluorescence, bright-field and TIRF capabilities. Imaging acquisition and analyses are performed using EZ-C1 and NIC-Elements Software.

Proper citation: MGH Confocal Microscope Core (RRID:SCR_009921) Copy   

•   Source: SciCrunch Registry

http://montana.eagle-i.net/i/0000012a-2502-98a0-f94c-e32480000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 22, 2025. Core facility that provides the following services: Microscopy facility training and access.

The Center for Biofilm Engineering Microscopy Facility is a research-only facility on the MSU campus, located on the third floor of the EPS building. The Microscopy Facilities Manager trains and assists faculty, research staff and students with capturing images of samples via optical microscopy and fluorescent confocal microscopy. The microscopy facilities include three separate laboratories - the Optical Microscopy Lab, the Confocal Microscopy Lab, and the Microscope Resource Room and Digital Imaging Lab. Large inventory of fluorescent stains. Inquire for availability, applications and collaborations.

Proper citation: MSU Microscopy Core Facility (RRID:SCR_009943) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013f-52ff-7e24-a468-831a80000000

The MR Sub-Core of the SAIF provides the instrumentation and expertise necessary to perform a broad spectrum of magnetic resonance imaging and spectroscopy studies on a wide range of biological samples including small animals (cats, rabbits, rats, mice), tissue specimens, cultured cells and tissue extracts. This facility includes a conveniently located, well equipped surgery room used for preparing the animals for MR exams and a wide assortment of supporting equipment, i.e. anesthesia machines, MR compatible vital signs monitors (SA Instruments), infusion pumps (Harvard), heating pads, etc. A variety of perishable supplies used in animal preparation are provided by the facility.

Proper citation: Penn Small Animal Imaging Facility: MRI/MRS Sub-Core (RRID:SCR_010032) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/gtp/vectorcore/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core whose main aim is to provide vector technology for preclinical studies and other basic research applications. Its services include rovision of AAV, adenoviral and lentiviral based vectors, consultation and advice in the design of custom vectors and in vector serotype/pseudotype selection, and design, cloning and production of plasmid DNA for the production of custom vectors.

Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Vector Core Facility (RRID:SCR_010038) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012a-250b-efe2-43fb-601a80000000

These laboratories house large, relatively expensive research instruments, which are shared among the faculty, students and staff on campus.

Proper citation: UPR RCMI Program Shared Instrumentation Laboratories (RRID:SCR_010132) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-c95d-a6f3-a272-8ee780000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Research support, Research Training. The DMSRSU provides study design, data management, quality assurance, and statistical analysis support for UCC researchers. The DMSRSU has a strong infrastructure which includes the following subunits: Data Abstraction and Management; Data Entry; Quality Control; Data Analysis and Consultant; and Administrative and Computer Systems. Each of these subunits consists of experienced professionals readily available to assist researchers and to provide data management and statistical research support to investigators. In addition, the DMSRSU counts on a highly experienced and reliable consulting team.

Proper citation: UCC Data Management and Statistical Research Support Unit (RRID:SCR_010074) Copy   

•   Source: SciCrunch Registry

http://www.premierbiosoft.com/dnamicroarray/index.html

Oligo and cDNA Microarray Design Software that designs thousands of primers and probes for oligo and cDNA microarrays in seconds.

Proper citation: Array Designer (RRID:SCR_010960) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/proteomics-metabolomics-facility/

Core facility that provides the following services: In-gel protease digestion service, LC-MS/MS protein identification service, Gel/LC-MS/MS Comprehensive analysis of a subproteome or proteome, MudPIT (LC/LC-MS/MS) analyis?comprehensive analysis of a subproteome or proteome, Reverse phase microbore HPLC peptide mapping service, MALDI mass spectrometry, ESI of intact proteins, Post-translational modification identifications, Custom proteomics database creation, Custom proteomics data analysis, Proteomics methods development. The Wistar Proteomics Facility provides mass spectrometry (MS) and sequence analysis of proteins and peptides at maximum sensitivity using state-of-the-art instruments and methods. The most commonly used services are identifications of either purified proteins or complex protein mixtures, such as sub-proteomes or complete proteomes, using electrospray ionization tandem mass spectrometry (ESI MS/MS). Typically, either individual bands are excised from 1-D SDS gels, or the entire gel lane is analyzed by slicing it into uniform fractions followed by trypsin digestion and nanocapillary HPLC interfaced directly with hybrid ion trap mass spectrometry (Gel/LC-MS/MS). Data is analyzed and filtered to produce low false-positive rates. Several options are available for quantitatively comparing protein changes in related samples, and additional options will be implemented in the future. Complementary services include reverse-phase microbore HPLC peptide mapping with UV detection and mass measurements of intact peptides and proteins using MALDI MS or ESI MS. Posttranslational modification (PTM) analyses including identifications of specific modified residues also are provided, although investigators should recognize that in most cases these studies are quite complex and require substantial effort. These studies, as well as analyses of complex protein mixtures, usually require preparation of custom sequence databases and/or custom data analyses, which can be provided by the facility as needed.

Proper citation: Wistar Proteomics and Metabolomics Core Facility (RRID:SCR_010211) Copy   

•   Source: SciCrunch Registry

http://www.systat.com/

A commercial software tool for statistical analysis.

Proper citation: SyStat (RRID:SCR_010455) Copy   

•   Source: SciCrunch Registry

http://www.genomics.agilent.com/en/Microarray-Data-Analysis-Software/GeneSpring-GX/?cid=AG-PT-130&tabId=AG-PR-1061

Powerful, accessible statistical tools for fast visualization and analysis of microarrays - expression arrays, miRNA, exon arrays and genomics copy number data.

Proper citation: GeneSpring GX (RRID:SCR_010972) Copy   

•   Source: SciCrunch Registry

http://datasift.net/

A portal that allows users to track specific words, phrases or nearby relationships from social media sources including Twitter, Digg and others. Datasift aggregates, filters, records, and analyzes real-time data from a variety of social sources using our Curation Stream Definition Language (CSDL) allowing customers to curate their own news.

Proper citation: DataSift (RRID:SCR_010708) Copy   

•   Source: SciCrunch Registry

http://protocols.io/

A commercial protocol sharing tool, which allows scientists to check in protocols the way that computer scientists check in code.

Proper citation: Protocols.io (RRID:SCR_010490) Copy   

•   Source: SciCrunch Registry

https://dna.uga.edu/

Core laboratory for nucleic acid sequencing and bioinformatics. Used for research support, education, and training. Services include genomic techniques and applications, sequencing technologies, and bioinformatics analyses, writting letters of support for grant applications submitted to funding agencies. GGBC operates multiple platforms for short-, long-, and single-molecule sequencing reads (i.e., Illumina MiSeq and NextSeq, PacBio Sequel, and Oxford Nanopore MinIon).

Proper citation: Georgia Genomics and Bioinformatics Core at the University of Georgia (RRID:SCR_010994) Copy   

•   Source: SciCrunch Registry

https://www.ibtbioservices.com/

Research organization offering R&D services to identify and develop vaccines and therapeutics for infectious diseases.

Proper citation: IBT Bioservices (RRID:SCR_012195) Copy   

•   Source: SciCrunch Registry