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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://github.com/calebclayreagor/DELAY
Software application as convolutional neural network for inference of gene-regulatory relationships across pseudotime-ordered single-cell trajectories. Used for depicting pseudotime-lagged causality for accurate gene-regulatory inference.
Proper citation: DELAY (RRID:SCR_027302) Copy
https://pypi.org/project/transformers/
Software framework for machine learning models in text, computer vision, audio, video, and multimodal model, for both inference and training.
Proper citation: Transformers (RRID:SCR_027381) Copy
https://bioconductor.org/packages/CNVMetrics/
Software R package to calculate similarity metrics to facilitate copy number variant comparison among samples and/or methods.
Proper citation: CNVMetrics (RRID:SCR_027263) Copy
https://github.com/wenmm/EssSubgraph/tree/main
A model algorithm that integrates omics data and network data to predict essential genes.
Proper citation: EssSubgraph (RRID:SCR_027354) Copy
Software application that provides search and clustering functionality, typically used with amplicon sequence data. Used to assign sequences to clusters.
Proper citation: USEARCH (RRID:SCR_027438) Copy
https://github.com/kermitt2/grobid
Software tool for extracting information from scholarly documents.
Proper citation: Grobid (RRID:SCR_027539) Copy
https://github.com/hejDMC/napari-dmc-brainmap
Software napari plugin for flexible mapping of various features (cell bodies, axonal densities, injections sites, optical fibers, Neuropixels probes) to standardized reference spaces included in BrainGlobe. Used for anatomical mapping.
Proper citation: DMC-BrainMap (RRID:SCR_027433) Copy
https://github.com/hejDMC/dmc-fluoimager
Software Python project for whole slide image acquisition using a fluorescence microscope.
Proper citation: DMC-FluoImager (RRID:SCR_027435) Copy
https://github.com/jmschrei/memesuite-lite
Software application as lightweight reimplementation of some of the algorithms in the MEME suite in Python.
Proper citation: memesuite-lite (RRID:SCR_027429) Copy
public research and teaching hospital network in Toronto, Ontario, Canada. It is affiliated with the Temerty Faculty of Medicine at the University of Toronto, and is the largest health research organization in Canada, ranking first in the country for total research funding.
Proper citation: University Health Network (RRID:SCR_027533) Copy
https://github.com/wheaton5/souporcell
Software tool to cluster cells using the genetic variants detected within the scRNAseq reads. Robust clustering of single-cell RNA-seq data by genotype without reference genotypes. Used for clustering scRNAseq by genotypes.
Proper citation: Souporcell (RRID:SCR_027462) Copy
https://github.com/HazyResearch/hyena-dna
Software application as long-range genomic foundation model pretrained on context lengths of up to 1 million tokens at single nucleotide resolution.
Proper citation: HyenaDNA (RRID:SCR_027471) Copy
https://github.com/MANO-B/U3-Nomogram
Software application for C-CAT CALICO database. Used for Germline-focUsed analysis of tUmoUr-detected variants with Nomogram for C-CAT CALICO database.
Proper citation: U3-Nomogram (RRID:SCR_027696) Copy
https://guolab.wchscu.cn/ImmuCellAI/#!/
Software tool for comprehensive T‐Cell subsets abundance prediction and its application in cancer immunotherapy.
Proper citation: ImmuCellAI (RRID:SCR_027645) Copy
https://atlantis.bioinfolab.sns.it
Integrative database for human proteome structural and functional sites. Used for understanding role of specific residues in protein structures, complexes, and interaction networks. Integrates various structural and functional annotation layers for each residue, offering comprehensive understanding of protein functionality.
Proper citation: Atlantis (RRID:SCR_027648) Copy
https://github.com/broadinstitute/multiVIB
Software tool as comprehensive framework for integration of single-cell omics data with probabilistic contrastive learning.
Proper citation: multiVIB (RRID:SCR_027589) Copy
https://github.com/cancerit/ClusterSV
Software application to group genetic structural variant rearrangements into rearrangement clusters and footprints. Used in the PCAWG-6 project.
Proper citation: ClusterSV (RRID:SCR_027722) Copy
https://github.com/BioDepot/SpatialProteomics
Software graphical and containerized spatial proteomics workflow. End-to-end containerized spatial proteomics analysis workflow with QuPath integration. Consists of cell segmentation, batch correction, unsupervised clustering, validation of clusters on the image, and cell type clustering results visualization.
Proper citation: SpatialProteomics (RRID:SCR_027835) Copy
https://github.com/bbglab/intogen-plus
Software tool for automatic and comprehensive knowledge extraction based on mutational data from sequenced tumor samples from patients. Summarizes somatic mutations, genes and pathways involved in tumorigenesis.
Proper citation: IntOGen (RRID:SCR_027727) Copy
https://github.com/eyzhao/hrdetect-pipeline
Software tool for detection and analysis of homologous recombination events.
Proper citation: HRDetect (RRID:SCR_027726) Copy
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